Patents by Inventor Peter H.R. Persicaner

Peter H.R. Persicaner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Natural combination hormone replacement formulations and therapies
    Patent number: 11103513
    Abstract: Pharmaceutical compositions for co-administering estradiol and progesterone to a human subject in need thereof are provided. In some embodiments, the pharmaceutical composition comprises solubilized estradiol, suspended progesterone, and a solubilizing agent comprising a medium chain (C6-C12) oil.
    Type: Grant
    Filed: May 27, 2020
    Date of Patent: August 31, 2021
    Assignee: TherapeuticsMD
    Inventors: Brian A. Bernick, Peter H. R. Persicaner, Julia M. Amadio
  • STEROID HORMONE PHARMACEUTICAL FORMULATIONS
    Publication number: 20210244747
    Abstract: This disclosure provides pharmaceutical compositions for delivering estradiol to a subject in need thereof, as well as methods of administering the compositions, and methods of using them.
    Type: Application
    Filed: February 5, 2021
    Publication date: August 12, 2021
    Inventors: Veeran Giwda KADAJJI, Mafruhul BARI, Annette Shadiack, Thorsteinn THORSTEINSSON, Peter H.R. PERSICANER
  • Soluble estradiol capsule for vaginal insertion
    Patent number: 11065197
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided. In various embodiments, such formulations are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Grant
    Filed: April 1, 2020
    Date of Patent: July 20, 2021
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Julia M. Amadio, Peter H. R. Persicaner, Thorsteinn Thorsteinsson, Janice Louise Cacace, Frederick D. Sancilio, Neda Irani
  • Progesterone formulations having a desirable pk profile
    Patent number: 11033626
    Abstract: This disclosure provides progesterone formulations, methods of using these formulations, and their related pharmacokinetic parameters. In particular embodiments, the formulations disclosed herein allow for a reduction in the amount of progesterone administered to a patient in need thereof, while still providing the benefits of a larger dosage amount.
    Type: Grant
    Filed: September 20, 2019
    Date of Patent: June 15, 2021
    Assignee: TherapeuticsMD, Inc.
    Inventors: Janice Cacace, Peter H. R. Persicaner, Thorsteinn Thorsteinsson, Frederick Sancilio, Julia Amadio, Brian Bernick, Neda Irani
  • Soluble estradiol capsule for vaginal insertion
    Patent number: 10888516
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided. In various embodiments, such formulations are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: January 12, 2021
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Julia M. Amadio, Peter H. R. Persicaner, Thorsteinn Thorsteinsson, Janice Louise Cacace, Frederick D. Sancilio, Neda Irani
  • Vaginal inserted estradiol pharmaceutical compositions and methods
    Patent number: 10835487
    Abstract: According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: November 17, 2020
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Julia M. Amadio, Peter H. R. Persicaner
  • SOLUBLE ESTRADIOL CAPSULE FOR VAGINAL INSERTION
    Publication number: 20200352961
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided. In various embodiments, such formulations are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Application
    Filed: April 1, 2020
    Publication date: November 12, 2020
    Applicant: TherapeuticsMD, Inc.
    Inventors: Brian A. BERNICK, Julia M. AMADIO, Peter H.R. PERSICANER, Thorsteinn THORSTEINSSON, Janice Louise CACACE, Frederick D. SANCILIO, Neda IRANI
  • Vaginal inserted estradiol pharmaceutical compositions and methods
    Patent number: 10806697
    Abstract: According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: October 20, 2020
    Assignee: TherapeuticsMD, Inc.
    Inventors: Brian A. Bernick, Julia M. Amadio, Peter H. R. Persicaner
  • Natural combination hormone replacement formulations and therapies
    Patent number: 10806740
    Abstract: Pharmaceutical formulations for co-administering estradiol and progesterone are provided herein. In some embodiments, the formulation comprises solubilized estradiol, suspended progesterone, and a medium chain (C6-C12) oil.
    Type: Grant
    Filed: October 10, 2014
    Date of Patent: October 20, 2020
    Assignee: TherapeuticsMD, Inc.
    Inventors: Peter H. R. Persicaner, Brian A. Bernick, Julia M. Amadio
  • SOLUBLE ESTRADIOL CAPSULE FOR VAGINAL INSERTION
    Publication number: 20200323881
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided. In various embodiments, such formulations are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Application
    Filed: June 25, 2020
    Publication date: October 15, 2020
    Inventors: Brian A. Bernick, Julia M. Amadio, Peter H.R. Persicaner, Thorsteinn Thorsteinsson, Janice Louise Cacace, Frederick D. Sancilio, Neda Irani
  • VAGINAL INSERTED ESTRADIOL PHARMACEUTICAL COMPOSITIONS AND METHODS
    Publication number: 20200297735
    Abstract: According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Application
    Filed: March 27, 2020
    Publication date: September 24, 2020
    Applicant: TherapeuticsMD, Inc.
    Inventors: Brian A. BERNICK, Thorsteinn THORSTEINSSON, Peter H.R. PERSICANER, Janice Louise CACACE, Frederick D. SANCILIO, Neda IRANI, Julia AMADIO
  • VAGINAL INSERTED ESTRADIOL PHARMACEUTICAL COMPOSITIONS AND METHODS
    Publication number: 20200297736
    Abstract: According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Application
    Filed: March 27, 2020
    Publication date: September 24, 2020
    Applicant: TherapeuticsMD, Inc.
    Inventors: Brian A. BERNICK, Thorsteinn THORSTEINSSON, Peter H.R. PERSICANER, Janice Louise CACACE, Frederick D. SANCILIO, Neda IRANI, Julia AMADIO
  • SOLUBLE ESTRADIOL CAPSULE FOR VAGINAL INSERTION
    Publication number: 20200289529
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided.
    Type: Application
    Filed: March 27, 2020
    Publication date: September 17, 2020
    Applicant: TherapeuticsMD, Inc.
    Inventors: Brian A. BERNICK, Julia M. AMADIO, Peter H.R. PERSICANER, Thorsteinn THORSTEINSSON, Janice Louise CACACE, Frederick D. SANCILIO, Neda IRANI
  • Natural Combination Hormone Replacement Formulations and Therapies
    Publication number: 20200281938
    Abstract: Pharmaceutical compositions for co-administering estradiol and progesterone to a human subject in need thereof are provided. In some embodiments, the pharmaceutical composition comprises solubilized estradiol, suspended progesterone, and a solubilizing agent comprising a medium chain (C6-C12) oil.
    Type: Application
    Filed: May 27, 2020
    Publication date: September 10, 2020
    Inventors: Brian A. BERNICK, Peter H.R. PERSICANER, Julia M. Amadio
  • NATURAL COMBINATION HORMONE REPLACEMENT FORMULATIONS AND THERAPIES
    Publication number: 20200281941
    Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
    Type: Application
    Filed: May 27, 2020
    Publication date: September 10, 2020
    Inventors: Brian A. Bernick, Janice Louise Cacace, Peter H.R. Persicaner, Neda Irani, Julia M. Amadio
  • Natural Combination Hormone Replacement Formulations and Therapies
    Publication number: 20200281940
    Abstract: Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
    Type: Application
    Filed: May 27, 2020
    Publication date: September 10, 2020
    Inventors: Brian A. BERNICK, Janice Louise CACACE, Peter H.R. PERSICANER, Neda IRANI, Julia M. AMADIO
  • VAGINAL INSERTED ESTRADIOL PHARMACEUTICAL COMPOSITIONS AND METHODS
    Publication number: 20200281849
    Abstract: According to various embodiments of this disclosure, pharmaceutical compositions comprising solubilized estradiol are provided. In various embodiments, such compositions are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Application
    Filed: March 30, 2020
    Publication date: September 10, 2020
    Applicant: TherapeuticsMD, Inc.
    Inventors: Brian A. BERNICK, Julia AMADIO, Peter H.R. PERSICANER
  • SOLUBLE ESTRADIOL CAPSULE FOR VAGINAL INSERTION
    Publication number: 20200276210
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided.
    Type: Application
    Filed: May 15, 2020
    Publication date: September 3, 2020
    Applicant: TherapeuticsMD, Inc.
    Inventors: Brian A. BERNICK, Julia M. AMADIO, Peter H.R. PERSICANER, Thorsteinn THORSTEINSSON, Janice Louise CACACE, Frederick D. SANCILIO, Neda IRANI
  • PROGESTERONE FORMULATIONS HAVING A DESIRABLE PK PROFILE
    Publication number: 20200268888
    Abstract: This disclosure provides progesterone formulations, methods of using these formulations, and their related pharmacokinetic parameters. In particular embodiments, the formulations disclosed herein allow for a reduction in the amount of progesterone administered to a patient in need thereof, while still providing the benefits of a larger dosage amount.
    Type: Application
    Filed: September 20, 2019
    Publication date: August 27, 2020
    Applicant: TherapeuticsMD, Inc.
    Inventors: Janice Cacace, Peter H.R. Persicaner, Thorsteinn Thorsteinsson, Frederick Sancilio, Julia Amadio, Brian Bernick
  • SOLUBLE ESTRADIOL CAPSULE FOR VAGINAL INSERTION
    Publication number: 20200230153
    Abstract: According to various embodiments of this disclosure, pharmaceutical formulations comprising solubilized estradiol are provided. In various embodiments, such formulations are encapsulated in soft capsules which may be vaginally inserted for the treatment of vulvovaginal atrophy.
    Type: Application
    Filed: April 1, 2020
    Publication date: July 23, 2020
    Applicant: TherapeuticsMD, Inc.
    Inventors: Brian A. BERNICK, Julia M. AMADIO, Peter H.R. PERSICANER, Thorsteinn THORSTEINSSON, Janice Louise CACACE, Frederick D. SANCILIO, Neda IRANI