Abstract: A bone plate system to fixate bone portions comprises a polymeric bone plate incorporating a 1× n aperture array of fastener apertures and a plurality of fasteners. The fastener apertures are undersized relative to the fasteners. The fasteners are made from a harder material than the at least one polymeric bone plate material in which the apertures are formed. The polymeric bone plate has a native configuration and an induced multi-curved configuration. The induced multi-curved configuration includes increased curvature comprising at least two of increased bending curvature, increased twisting curvature, and/or increased lateral curvature relative to the native configuration. Inserting the fasteners into the fastener apertures volumetrically displaces portions of the at least one bone plate material in a manner effective to induce the polymeric bone plate to transition from the native configuration to the multi-curved configuration.

Abstract: A catheter assembly, including a delivery catheter including a delivery catheter body defining an inner lumen of the delivery catheter. The catheter assembly includes a working catheter including a modification device. The working catheter extends through the inner lumen of the delivery catheter, and the working catheter is selectively couplable with the delivery catheter.

Abstract: Provided herein are variant ?4?7 integrin antibodies and methods of use.

Abstract: Provided is a method for authentication. The method may include receiving first password data, first biometric input data, and first secret key data. A second secret key may be generated based on the first secret key and the first password. Fuzzy extractor helper data may be generated based on the first biometric input and the second secret key. The fuzzy extractor helper data and the first secret key may be stored. The user may be authenticated based on an attempted password and/or a second biometric input. A system and computer program product are also disclosed.

Abstract: Systems and methods for providing an interbody implant are disclosed. According to some implementations, the implant includes an implant body having a cranial face and a caudal face disposed opposite the cranial face. In some implementations, the implant includes one or more primary fixation mechanisms, which in turn can include one or more anchor cavities defined by the implant body. In some cases, one or more anchors are configured to be housed at least partially within the anchor cavities in an undeployed position, and the anchors are configured to be translationally deployed to a deployed position in order to couple the implant to a bony endplate of a spinal vertebra. In some implementations, the implant includes one or more actuators configured to effectuate selective deployment of the anchors.

Abstract: This invention relates to a weighbridge (10) having a deck (20) and a bridging portion (50). The deck has first (22) and second ends (24) the bridging portion (50) has a first end (50a) attached to an end (22) of the deck (20) and a free end at second end (50b). The bridging portion (50) is configured to provide a bridge between the end (22) of the deck (22) and a static substrate, in use.

Abstract: A method for providing weight accuracy indications for scales, such as vehicle scales, and systems are provided. A controller receives load data from a weighment from one or more sensors of the scale and determines a weight reading. The controller determines an estimated error magnitude for the weighment based on at least one of: at least a portion of the load data and additional data. The weight reading is electronically displayed at a user device along with at least one additional item based on the estimated error magnitude for the weighment.

Abstract: A bean roasting system comprises a roasting drum including (1) a housing enclosing a roasting chamber and having a curved inner surface defined by a curved lower wall, and (2) an air inlet chamber fluidically coupled to the roasting chamber and configured to direct air toward the curved inner surface which redirects the air in a first rotational direction. A distal end of each blade from a plurality of blades is disposed from a axis of rotation toward the curved lower wall by a distance no greater than R. The curved lower wall is spaced at least a distance R+G from the axis of rotation to provide a minimum gap G. The agitator blade set and the directed air are collectively prevents accumulation of beans along the curved lower surface during a roasting process.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer-readable media that generates a design representation to further construct a digital design multigraph and generate a structural representation for a digital design document from the digital design multigraph. For instance, the disclosed systems generate a design representation of a digital design document that includes design properties with multiple digital design elements. In particular, the disclosed systems construct a digital design (multi-)graph from the design representation by generating nodes to represent digital design elements and edges based on relationships between these elements. In addition, the disclosed systems generate a structural representation based on the digital design multigraph for downstream applications.

Abstract: Provided are compounds comprising a ligand LA of Formula I where the ligand LA is coordinated to Pt.

Abstract: A packet-filtering network appliance such as a threat intelligence gateway (TIG) protects TCP/IP networks from Internet threats by enforcing certain policies on in-transit packets that are crossing network boundaries. The policies are composed of packet filtering rules derived from cyber threat intelligence (CTI). Logs of rule-matching packets and their associated flows are sent to cyberanalysis applications located at security operations centers (SOCs) and operated by cyberanalysts. Some cyber threats/attacks, or incidents, are composed of many different flows occurring at a very high rate, which generates a flood of logs that may overwhelm computer, storage, network, and cyberanalysis resources, thereby compromising cyber defenses.

Abstract: The present invention relates to a functionalised polymer, methods of preparing the functionalised polymer, and compositions comprising the functionalised polymer. The present invention also relates to methods of using the functionalised polymer including for forming a polymer composition comprising cells from a tissue sample and for cell therapy.

Abstract: An oscillating drive mechanism for a surgical tool includes a motor having a rotor, a crank assembly hub, a link secured to the crank assembly hub, a pivot shaft, a shuttle including an arcuate rack gear secured to the link so that rotation of the crank assembly hub provides reciprocating rotary motion to the arcuate rack gear about the pivot shaft. A gear is meshed with the arcuate rack gear and is secured to an output shaft, whereby rotational motion of the motor induces rotary oscillating motion to the output shaft.

Abstract: The present disclosure is directed to a method of manufacture of zeolite. A sol-gel formulation includes a water-soluble fraction of ODSO as an additional component. The resulting products include zeolite with a relative acidity per mole of Al that is greater than a comparative zeolite which is formed in the absence of ODSO and of approximately equivalent compositional ratio effective for the zeolite except for water instead of the added ODSO.

Abstract: The present invention relates to a method of determining the total organic carbon content (TOC) of a purified water stream in a water purification apparatus having at least a first pump, a first conductivity sensor, an oxidiser, and an oxidiser recirculation circuit having a dedicated second pump, the method comprising at least the steps of: (a) using the first pump to pass a water supply stream through the water purification apparatus, including through the first conductivity sensor and the oxidiser, to provide a purified water stream available for dispense; (b) using the first conductivity sensor to measure a first conductivity value of the water supply stream prior to the oxidiser; (c) stopping the first pump; (d) using the second pump in the oxidiser recirculation circuit to recirculate the water in the oxidiser only through the first conductivity sensor and the oxidiser a plurality of times, (e) using the first conductivity sensor to measure a second conductivity value of the recirculated water; and (

Abstract: A discrimination system with optics that collect output electromagnetic radiation from sperm cells within a measurement region, a split detector that generates an electrical signal responsive to the intensity of the collected electromagnetic radiation and which detects the position of sperm cells in the measurement region, and an analyzer for discriminating between X-chromosome bearing sperm and Y-chromosome bearing sperm in the measurement region.

Abstract: A strengthened cover glass or glass-ceramic sheet or article as well as processes and systems for making the strengthened glass or glass-ceramic sheet or article is provided for use in consumer electronic devices. The process comprises cooling the cover glass sheet by non-contact thermal conduction for sufficiently long to fix a surface compression and central tension of the sheet. The process results in thermally strengthened cover glass sheets for use in or on consumer electronic products.

Abstract: An apparatus may include a substrate. The apparatus may also include a first charger terminal disposed on the substrate, including silver, and configured to apply a first electric potential to a first battery terminal of a battery. The apparatus may additionally include a second charger terminal disposed on the substrate, comprising silver, and configured to apply a second electric potential to a second battery terminal of the battery.

Abstract: Provided herein are methods using machine learning to predict protein variants that are likely to occur in nature. Such variants can be used (selected) to improve properties of the proteins. Also provided herein are antibodies and antigen binding portions thereof generated using the provided methods that specifically bind several antigens from coronaviruses, ebolaviruses, and influenza A viruses, various compositions of such antibodies or antigen binding portions thereof, recombinant nucleic acids encoding the antibodies and antigen binding portions thereof, and associated methods of use.

Abstract: The present invention relates to multi-domain, single-chain binding molecules. The molecules comprise i) a peptide-major histocompatibility complex (pMHC) binding domain which binds to a SLLQHLIGL (SEQ ID NO: 1) HLA-A*02 complex, the pMHC domain comprising a first variable region linked to a constant region (VC1) and a second variable region linked to a constant region (VC2); ii) a T cell engaging immune effector domain comprising an antibody light chain variable region (TCE-VL) and an antibody heavy chain variable region (TCE-VH); and iii) a half-life extending domain comprising a first IgG Fc region (FC1) and a second IgG Fc region (FC2), wherein the FC1 region and FC2 region dimerise to form an Fc domain. The binding molecules can be used to treat diseases such as cancer.