Abstract: Described herein are an emulsifiable concentrate (EC) including one or more pesticides, one or more emulsifiers and certain lactone-derived solvents, an emulsion-in-water (EW) formulation formed from the emulsifiable concentrate (EC), and a method of using the certain lactone-derived solvents as a solvent in an agrochemical emulsifiable concentrate.

Abstract: A method may include obtaining, for a thread executing application code, a recurring task, a recurring interval, a previous callback time, a starting counter value, and a counter trigger, initializing a current counter value to the starting counter value, and performing checks in response to adjustments to the current counter value. Each check may determine whether the respective adjusted current counter value satisfies the counter trigger. The method may further include in response to a check determining that the adjusted current counter value satisfies the counter trigger, invoking a callback handler with a callback that performs the recurring task, and in response to an elapsed time exceeding the recurring interval, executing, by the callback handler, the callback. The elapsed time may be an amount of time elapsed between the previous callback time and the first invocation. The method may further include modifying the starting counter value using the elapsed time.

Abstract: A method may include generating, for a host application, an image including an image heap including objects and a writeable object partition including a subset of the objects. The method may further include initializing, by executing the image in a process of a computer system, a first isolate including a first address space and a first read-only map of the image heap. The first read-only map may designate the writeable object partition of the image heap as copy-on-write. The method may further include initializing, by executing the image in the process, a second isolate including a second address space and a second read-only map of the image heap. The method may further include performing, in the first isolate and using the first read-only map, a first task that accesses an object, and performing, in the second isolate and using the second read-only map, a second task that accesses the object.

Abstract: A method may include obtaining, for a thread executing application code, a recurring task, a recurring interval, a previous callback time, a starting counter value, and a counter trigger, initializing a current counter value to the starting counter value, and performing checks in response to adjustments to the current counter value. Each check may determine whether the respective adjusted current counter value satisfies the counter trigger. The method may further include in response to a check determining that the adjusted current counter value satisfies the counter trigger, invoking a callback handler with a callback that performs the recurring task, and in response to an elapsed time exceeding the recurring interval, executing, by the callback handler, the callback. The elapsed time may be an amount of time elapsed between the previous callback time and the first invocation. The method may further include modifying the starting counter value using the elapsed time.

Abstract: A method may include generating, for a host application, an image including an image heap including objects and a writeable object partition including a subset of the objects. The method may further include initializing, by executing the image in a process of a computer system, a first isolate including a first address space and a first read-only map of the image heap. The first read-only map may designate the writeable object partition of the image heap as copy-on-write. The method may further include initializing, by executing the image in the process, a second isolate including a second address space and a second read-only map of the image heap. The method may further include performing, in the first isolate and using the first read-only map, a first task that accesses an object, and performing, in the second isolate and using the second read-only map, a second task that accesses the object.

Abstract: Suggested are agrochemical compositions, comprising (a) biocides, and (b) alkoxylation products of di- and/or oligosaccharide esters.

Abstract: Suggested are agrochemical compositions, comprising (a) biocides, and (b) alkoxylation products of di- and/or oligosaccharide esters.

Abstract: Suggested is an improved process for making polyol esters with improved colour quality by transesterification of polyols or their alkoxylation products with fatty acid alkyl esters, which is characterised in that the reaction is carried out in the presence of a reducing mineral or organic acid as a catalyst selected from the group consisting of (i) sulphuric or sulphonic acids with an oxidation value of sulphur of less than 6 or their salts, and/or (ii) phosphoric or phosphonic acids with an oxidation value of phosphor of less than 5 or their salts.

Abstract: The invention is related to alkylene oxide adducts of oligosaccharides, obtained by a process comprising alkoxylating at least one water-soluble oligosaccharide in aqueous solution at a temperature in the range of 90 to 160° C. The compounds are useful as adjuvants in agrochemical compositions.

Abstract: In a method for determining an absolute number of electron spins in an extended sample (3) with the assistance of an apparatus for measuring magnetic resonance, the extended sample (3) is disposed within a measurement volume (2) of a radiofrequency RF resonator (1) of the apparatus during an electron spin resonance measurement (ESR).

Abstract: The present invention comprises compounds having the general formula I: 1

Abstract: Disclosed are compounds having formula (II): wherein: Q3, Q6a, Q6b and Q8 are independently a bond, C1-8 alkylene, C2-8 alkenylene and C2-8 alkynylene, and R3, R6a, R6b and R8 are independently hydrogen, aryl or heteroraryl, optionally substituted by halogen, hydroxy, alkoxy, nitro, cyano and carboxy, provided that: Q3R3 is not hydrogen or methyl. The compounds are effective PDE IV inhibitors and possess improved PDE IV inhibition and improved selectivity with regard to PDE III inhibition.

Abstract: Disclosed are compounds of the formula: wherein R3, R6a, R6b and R8 are substituted as disclosed herein. The compounds are effective in effecting PDE IV inhibition in patients in need thereof.

Abstract: Novel compounds which are effective PDE IV inhibitors are disclosed. The compounds possess improved PDE IV inhibition as compared to theophylline or rolipram, with improved selectivity with regard to, e.g., PDE III inhibition.

Abstract: Novel compounds which are effective PDE IV inhibitors are disclosed. The compounds possess improved PDE IV inhibition compared to theophylline or rolipram, with improved selectivity with regard to, e.g., PDE V inhibition. The present invention includes compounds of Formula I: wherein the substituents are as disclosed herein.

Abstract: A compound of the formula: wherein R2 is O or S; R3, R6a and R8 are the same or different and each represent a C1-8 alkyl which is unbranched or branched and unsubstituted or substituted with OH, alkoxy, CO2H, ═NOH, ═NOCONH2, or ═O; C3-8 cycloalkyl which is unsubstituted or substituted with OH, alkoxy, CO2H, ═NOH, ═NOCONH2, or ═O; C4-8 cycloalkylalkyl wherein the cycloalkyl portion is unsubstituted or substituted with OH, alkoxy, CO2H, ═NOH, ═NOCONH2, or ═O; aryl which is unsubstituted or substituted with Cl, NH2, alkylamino, dialkylamino, amido, C1-C8 alkylamido, C1-C3 dialkylamido, OH, alkoxy, HC═NOH, HC═NOCONH2, C1-C3 alkyl, phenyl or benzyl; aralkyl (C1-4); heterocyclyl; heterocyclylalkyl (C1-C4); and heteroaryl; R6b represents a H or R6a, or together R6b, N, and R6a make a 3 to 8 member ring containing at least one carbon, from one to three nitrogen atoms, from zero to two oxygen atoms, from zero to two sulfur atoms, said ring op

Abstract: Hypoxanthine compounds of the structure: are disclosed where R3 and R8 are as described herein. The compounds are useful as intermediates to compounds providing PDE IV inhibition activity.

Abstract: A compound of the formula: wherein R3 represent a C1-8 alkyl which is unbranched or branched and unsubstituted or substituted with OH, alkoxy, CO2H, ═NOH, ═NOCONH2, or ═O; C3-8 cycloalkyl which is unsubstituted or substituted with OH, alkoxy, CO2H, ═NOH, ═NOCONH2, or ═O; C4-8 cycloalkylalkyl wherein the cycloalkyl portion is unsubstituted or substituted with OH, alkoxy, CO2H, ═NOH, ═NOCONH2, or ═O; aryl which is unsubstituted or substituted with Cl, NH2, alkylamino, dialkylamino, amido, C1-C8 alkylamido, C1-C3 dialkylamido, OH, alkoxy, HC═NOH, HC═NOCONH2, C1-C3 alkyl, phenyl or benzyl; aralkyl (C1-4); heterocyclyl; heterocyclylalkyl (C1-C4); and heteroaryl; R8 represents H or a C1-8 alkyl which is unbranched or branched and unsubstituted or substituted with OH, alkoxy, CO2H, ═NOH, ═NOCONH2, or ═O; C3-8 cycloalkyl which is unsubstituted or substituted with OH, alkoxy, CO2H, ═NOH, ═NOCONH2, or ═O; C4-8 cyclo

Abstract: Disclosed is a compound selected from the group consisting of 1,3,8-triethyl-2,6-dithioxanthine; 1,3,8-triethyl-2-thioxanthine; 8-cyclopropyl-1-ethyl-3-(2-methyl-butyl)-6-thioxanthine; 1,3-diethyl-8-isopropyl-6-thioxanthine; 8-cyclopropyl-1,3-dipropyl-6-thioxanthine; 8-isopropyl-1,3-dipropyl-6-thioxanthine; 1,3-diethyl-8-cyclopropyl-2,6-dithioxanthine; 1-(4-chlorobenzyl)-3-ethyl-8-isopropyl-6-thioxanthine; and 8-cyclopropyl-1,3-diethyl-6-thioxanthine. Also disclosed is a pharmaceutical composition comprising at least one pharmaceutically acceptable carrier and a compound selected from the group above. Also disclosed is a method of effecting PDE IV inhibition which comprises administering to a patient suffering from a disease or disorder selected from the group consisting of asthma, allergies, PDE IV modulated inflammation, and depression, a therapeutically effective amount of a compound selected from the group above.

Abstract: With the above and other objects in view, the present invention comprises compounds having the general formula (I): wherein: R1 is a C2-8 alkyl, C2-8 alkenyl, C2-8 alkynyl, C3-8 cycloalkyl, C3-8 cycloalkenyl or cycloalkynyl, wherein said alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl or cycloalkynyl is optionally substituted with hydroxy, C1-5 alkoxy, C3-5 cycloalkoxy, halogen, oxo, carbamido, hydroxycarbamido, oximido, C1-5 alkyloximido, C3-5 cycloalkyloximido, C1-5 acyloximido or C3-5 cycloacyloximido; Q is methylene or ethylene; R3 is aryl or heteroaryl wherein said aryl or heteroaryl has one to three substituents selected from the group consisting of C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-6 cycloalkyl, C3-6 cycloalkenyl, cycloalkynyl, C3-5 alkylene, C3-5 cycloalkylene, haloC1-6 alkyl, haloC1-6 cycloalkyl, hydroxy, C1-5 alkoxy, C3-5 cycloalkoxy, C1-2 alkylenedioxy, C1-6 acyl, C3-6 cycloacyl, C1-6 acyloxy, C3-6 cycloacyloxy, halogen, nitro or cyano; R8 is C1-5 alkyl or C3-5 cycl