Abstract: In a method for manufacturing a food product, a closed dough preform is formed having an arcuate portion that is at least partially hollow. The dough preform is cooked to form a comestible item having an internal chamber in the arcuate portion. The preform has an internal space that is closed off from communication with the ambient atmosphere so that the preform has no openings or holes in an external surface that communicate with the internal space or hollow interior of the preform. An apparatus for carrying out the method includes a transport mechanism moving the dough preforms from an assembly line to a heating device.

Abstract: Disclosed is a conduit that provides a bypass around an occlusion or stenosis in a coronary artery. The conduit is a tube adapted to be positioned in the heart wall to provide a passage for blood to flow between a heart chamber and a coronary artery, at a site distal to the occlusion or stenosis. The conduit has a section of blood vessel attached to its interior lumen which preferably includes at least one naturally occurring one-way valve positioned therein. The valve prevents the backflow of blood from the coronary artery into the heart chamber.

Abstract: Disclosed is a conduit that provides a bypass around an occlusion or stenosis in a coronary artery. The conduit is a tube adapted to be positioned in the heart wall to provide a passage for blood to flow between a heart chamber and a coronary artery, at a site distal to the occlusion or stenosis. The conduit has a section of blood vessel attached to its interior lumen which preferably includes at least one naturally occurring one-way valve positioned therein. The valve prevents the backflow of blood from the coronary artery into the heart chamber.

Abstract: A composition of microscopic devices utilizable in a medical diagnostic or therapeutic procedure. Each microscopic device includes a nanostructure provided with a ligand for effectively coupling the nanostructure to a predetermined chemical or molecular site. A medical method in part comprises inserting the medical devices into a patient, attaching the nanostructures via the respective ligands to instances of a predetermined type of target structure inside the patient, and thereafter activating the nanostructures to perform a preselected medical diagnostic or therapeutic function.

Abstract: A medical system includes a multiplicity of electromechanical transducers disposable in effective pressure-wave-transmitting contact with a patient and mounted to a carrier. Energization componentry is operatively connected to a first plurality of the transducers for supplying the same with electrical signals to produce first pressure waves in the patient. A control unit is operatively connected to the energization componentry and includes an electronic analyzer operatively connected to a second plurality of the transducers for performing electronic 3D volumetric data acquisition and imaging of internal tissue structures. The control unit includes phased-array signal processing circuitry for effectuating an electronic scanning of the internal tissue structures which facilitates one-dimensional, 2D, and 3D data acquisition and circuitry for defining multiple data gathering apertures and for coherently combining structural data from the respective apertures to increase spatial resolution.

Abstract: A composition of microscopic devices utilizable in a medical diagnostic or therapeutic procedure. Each microscopic device includes a nanostructure provided with a ligand for effectively coupling the nanostructure to a predetermined chemical or molecular site. A medical method in part comprises inserting the medical devices into a patient, attaching the nanostructures via the respective ligands to instances of a predetermined type of target structure inside the patient, and thereafter activating the nanostructures to perform a preselected medical diagnostic or therapeutic function.

Abstract: A medical apparatus includes a scanner for generating raw image data of internal tissue structures of a patient, and a computer operatively connected to the scanner and programmed to derive a three-dimensional electronic map or model of the internal tissue structures from the raw data. An image reproduction device is operatively connected to the computer for reproducing the map or model in a visually readable format. The computer controls the image reproduction device to reproduce the map or model. The visually readable format includes graphical representations of the tissue structures alignable on a skin surface of the patient with the tissue structures. In use, a medical practitioner inserts a sharp instrument into a patient through the reproduced map, using the map as a locator assist.

Abstract: In a method for treating cancer, a series of investigatory pressure waves of respective different preselected frequencies are generated in a patient so that the pressure waves are transmitted to a tumor through overlying tissues, while responsive oscillatory motion of the tumor and at least some internal tissues of the patient proximate to the tumor are monitored during this pressure wave generation. From the responsive oscillatory motion of the tumor and the internal tissues, a pressure wave frequency is determined which results in a resonant loading of the tumor and essentially leaves the internal tissues undamaged. Subsequently, treatment pressure waves are generated in the patient and have the determined pressure wave frequency and of an effective amplitude so that the tumor resonates with sufficient energy to mechanically destroy the tumor.

Abstract: A medical system includes a carrier and a multiplicity of electromechanical transducers mounted to the carrier, the transducers being disposable in effective pressure-wave-transmitting contact with a patient. Energization componentry is operatively connected to a first plurality of the transducers for supplying the same with electrical signals of at least one pre-established ultrasonic frequency to produce first pressure waves in the patient. A control unit is operatively connected to the energization componentry and includes an electronic analyzer operatively connected to a second plurality of the transducers for performing electronic 3D volumetric data acquisition and imaging (which includes determining three-dimensional shapes) of internal tissue structures of the patient by analyzing signals generated by the second plurality of the transducers in response to second pressure waves produced at the internal tissue structures in response to the first pressure waves.

Abstract: Disclosed is a conduit that provides a bypass around an occlusion or stenosis in a coronary artery. The conduit is a tube adapted to be positioned in the heart wall to provide a passage for blood to flow between a heart chamber and a coronary artery, at a site distal to the occlusion or stenosis. The conduit has a section of blood vessel attached to its interior lumen which preferably includes at least one naturally occurring one-way valve positioned therein. The valve prevents the backflow of blood from the coronary artery into the heart chamber.

Abstract: A cardiac insert or implant is deployed in a patient's heart so as to reduce ventricular volume, thereby improving cardiac function. The insert or implant may be a compressive device such as a tensile member inserted into the patient's heart, and thereafter operated or deployed to bring opposite walls of a ventricle of the patient's heart into at least approximate contact with one another to thereby constrict and close off a lower portion of that ventricle. The compressive device or tensile member is insertable into the patient heart via a catheter threaded through the patient's vascular system and into the patient's heart.

Abstract: A medical system includes a carrier and a multiplicity of electromechanical transducers mounted to the carrier, the transducers being disposable in effective pressure-wave-transmitting contact with a patient. Energization componentry is operatively connected to a first plurality of the transducers for supplying the same with electrical signals of at least one pre-established ultrasonic frequency to produce first pressure waves in the patient. A control unit is operatively connected to the energization componentry and includes an electronic analyzer operatively connected to a second plurality of the transducers for performing electronic 3D volumetric data acquisition and imaging (which includes determining three-dimensional shapes) of internal tissue structures of the patient by analyzing signals generated by the second plurality of the transducers in response to second pressure waves produced at the internal tissue structures in response to the first pressure waves.

Abstract: Methodology and related medical devices for effectively bypassing a blocked or partially blocked coronary artery and providing oxygenated blood to the myocardium. A coronary artery bypass method utilizes a shunt member. An upstream end portion of the shunt member is disposed in the myocardium of a patient's heart so that the upstream end portion communicates with the left ventricle of the patient's heart. An opposite or downstream end portion of the shunt member is placed in communication with a coronary artery of the patient downstream of a blockage in the coronary artery. The shunt member extends into the coronary artery from the myocardium either directly or indirectly with an intermediate or middle portion of the shunt member being disposed in an intrapericardial space of the patient, outside of the myocardium and outside of the coronary artery.

Abstract: A composition of microscopic devices utilizable in a medical diagnostic or therapeutic procedure. Each microscopic device includes a nanostructure provided with a ligand for effectively coupling the nanostructure to a predetermined chemical or molecular site. A medical method in part comprises inserting the medical devices into a patient, attaching the nanostructures via the respective ligands to instances of a predetermined type of target structure inside the patient, and thereafter activating the nanostructures to perform a preselected medical diagnostic or therapeutic function.

Abstract: A medical cauterization snare assembly with a tubular member, an electrically conductive cauterization loop ejectable from a distal end of the tubular member, and a capture pouch also ejectable from the distal end of the tubular member. The pouch is attached to an auxiliary loop which has a size larger than that of the cauterization loop. Alternatively, the tubular member is formed at its distal end with a first port or opening and in a distal end portion with a second port or opening spaced from the first port or opening. The two ports or openings both face in a distal direction (i.e., away from the user). The cauterization loop is alternately ejectable from and retractable into the first port or opening, while the capture pouch is separately ejectable from the second port or opening. Alternatively, the capture pouch is attached to the cauterization loop, to only a proximal portion of the loop to divide the loop's area into a proximal section covered by the pouch and an open or uncovered distal section.

Abstract: In a method for improving cardiac function, a compressive device is inserted into an intrapericardial space about a lower end portion of a heart. Thereafter the compressive device is operated to compress and close off lower portions of both ventricles of the heart.

Abstract: Disclosed is a conduit that provides a bypass around a stenosis or occlusion in a coronary artery. The conduit is adapted to be positioned in the myocardium to provide a passage for blood to flow from a heart chamber to a coronary artery, at a site distal to the blockage or stenosis in the coronary artery. The conduit has a one-way valve positioned therein to prevent the backflow of blood from the coronary artery into the heart chamber.

Abstract: A method for investigating structural integrity utilizes a carrier member having a flexible surface and a plurality of electromechanical transducer elements attached to the carrier member, the transducer elements being spaced from each other along at least two spatial dimensions. The method includes conforming the flexible surface to a solid structural member, so that a substantial portion of the flexible member is in effective wave-transmitting engagement with the structural member, thereafter transmitting pressure waves from at least one of the transducer elements into the structural member, receiving pressure waves reflected from an internal structural defect in the structural member in response to the pressure waves transmitted from the one of the transducer elements, and analyzing the received pressure waves so as to detect the structural defect.

Abstract: In a method for facilitating financing of new technology, a host computer is connected to a global computer network for receiving, over the network from remote computers, information describing purported advances in technology. The host computer is accessed, for example, by a user, to obtain the information downloaded from the global computer network. An evaluation of the advances in technology so obtained is then performed to determine, for each of the advances, a fixed monetary amount to be contributed in exchange for a unit of equity in a prospective technology development venture to develop the respective advance. Identifications of the advances together with respective values of the determined fixed monetary amounts are transmitted over the global computer network to preselected computers.

Abstract: A conduit is provided to provide a bypass around a blockage in the coronary artery. The conduit is adapted to be positioned in the myocardium or heart wall to provide a passage for blood to flow between a chamber of the heart such as the left ventricle and the coronary artery, distal to the blockage. The stent is self-expanding or uses a balloon to expand the stent in the heart wall. Various attachment means are provided to anchor the stent and prevent its migration.