Abstract: An integrated vectorcardiogram (VCG) device having 3 pairs of electrodes placed in three orthogonal directions with the capability to continuously measure the electrical activity of the heart. All of the electrode pairs may be contained within a single miniaturized housing thereby eliminating the need for cumbersome wires required with current 12-lead ECG systems, while providing the same amount and quality of information as the 12-lead ECG system. The integrated VCG device also includes a communications function to allow the data collected by the electrodes to be transmitted wirelessly to a remote device, such as a pacemaker, to control its function or to a remote monitoring station for continuous real-time patient monitoring.

Abstract: An image article comprises a substrate having a security image coated on at least a portion thereof, which security image effects less than 50% reflectance of radiation of a wavelength between 800 and 900 nm, wherein the security image comprises a defined infrared-absorbing compound, for example Pigment Green 8, wherein said infrared-absorbing compound does not create a strongly colored security image.

Abstract: A scanner (200) is arranged to detect a unique spectral signature acquired from a sample (230) coded with a security marker (700) made up from one or more overt or covert coloured features (704a-704b) having known and uniquely identifiable spectral characteristics. More particularly, a narrowband light source (218), operating in the middle/near ultraviolet to short/near infra-red wavelength ranges, pulses light onto the security marker fixed to or formed in the sample (230). A lens system (222, 216) collects spectral data for analysis by a processing engine (201), such as a smartphone. The light source (218), which may be an array of differently coloured LEDs (224), selectively illuminates the security marker with discrete wavelengths as LEDs are selectively energized. The coloured features (704a-704d) are realized by combinations of dyes, pigments or inks that may fluoresce that are difficult to replicate and therefore typically pantone-based. The coloured features each have unique spectral responses, i.e.

Abstract: Methods for treating Down syndrome and improving cognitive function of a patient with an intellectual disability are disclosed. 5-hydroxytryptamine sub-receptor six (5-HT 6) receptor antagonists are provided for improving the cognition of a Down syndrome patient. Through the use of a mouse model of DS, the Ts65Dn mouse, we disclose evidence herein that 5-HT 6 receptor antagonists may alleviate the cognitive deficits observed in human subjects suffering from DS. Species within the claimed genus of 5-HT6 receptor antagonists restored the cognitive function of Ts65Dn mice almost to the level of control mice as demonstrated by an improved ability to differentiate between a familiar object in a familiar location and a novel object in a novel location. Consequently, the data disclosed herein support the claimed use of 5-HT 6 receptor antagonists for the treatment of cognitive deficits associated with DS.

Abstract: An integrated vectorcardiogram (VCG) device having 3 pairs of electrodes placed in three orthogonal directions with the capability to continuously measure the electrical activity of the heart. All of the electrode pairs may be contained within a single miniaturized housing thereby eliminating the need for cumbersome wires required with current 12-lead ECG systems, while providing the same amount and quality of information as the 12-lead ECG system. The integrated VCG device also includes a communications function to allow the data collected by the electrodes to be transmitted wirelessly to a remote device, such as a pacemaker, to control its function or to a remote monitoring station for continuous real-time patient monitoring.

Abstract: Methods for treating Down syndrome and improving cognitive function of a patient with an intellectual disability are disclosed. 5-hydroxytryptamine sub-receptor six (5-HT6) receptor antagonists are provided for improving the cognition of a Down syndrome patient.

Abstract: Methods for treating Down syndrome and improving cognitive function of a patient with an intellectual disability are disclosed. 5-hydroxytryptamine sub-receptor six (5-HT6) receptor antagonists are provided for improving the cognition of a Down syndrome patient.

Abstract: An anesthetic administration device comprising an infusion device, which is in fluid connection with a regional anesthetic needle by means of a feed tube. The infusion device comprises one or more anesthetic flow devices capable of triggering forward flow, and optionally backward flow, of the local anesthetic through the regional anesthetic needle. Forward, and optionally backward flow, of the local anesthetic through the regional anesthetic needle is controlled by a controller that comprises one or more actuator switches. The one or more actuator switches are positioned on the device such that they may be operated by hand.

Abstract: A sampling connector for use in sampling a body fluid such as arterial blood or cerebrospinal fluid. The sampling connector comprises at least two apertures in fluid communication via a fluid flow conduit and a one-way valve (14) disposed to allow fluid flow from the first aperture, through the fluid flow conduit and out of the second aperture, but not to allow fluid to flow into the second aperture and through the fluid flow conduit to the first aperture. In use, the sampling connector is connected to a body cavity to enable the sampling of a body fluid by withdrawal of the body fluid through the first aperture, and to prevent the introduction of a separate fluid to the body cavity. The first aperture can be within a male end and the second aperture can be within a female end or vice versa. A sampling device comprising a sampling connector according to the present invention and use of the sampling connector and/or sampling device is also claimed.

Abstract: A flow generator includes a housing, a blower structured to generate a flow of pressurized breathable air, and a suspension device to support the blower within the housing and provide a pressure seal between low and high pressure sides of the blower. The suspension device includes a bellows-like portion provided along the perimeter of the blower to absorb shock applied at least radially to the blower and one or more cones provided along upper and/or lower sides of the blower to absorb shock applied at least axially to the blower.

Abstract: A computer implemented method for fusing images taken by a plurality of cameras is disclosed, comprising the steps of: receiving a plurality of images of the same scene taken by the plurality of cameras; generating Laplacian pyramid images for each source image of the plurality of images; applying contrast normalization to the Laplacian pyramids images; performing pixel-level fusion on the Laplacian pyramid images based on a local salience measure that reduces aliasing artifacts to produce one salience-selected Laplacian pyramid image for each pyramid level; and combining the salience-selected Laplacian pyramid images into a fused image. Applying contrast normalization further comprises, for each Laplacian image at a given level: obtaining an energy image from the Laplacian image; determining a gain factor that is based on at least the energy image and a target contrast; and multiplying the Laplacian image by a gain factor to produce a normalized Laplacian image.

Abstract: A method and apparatus for optimizing image quality based on scene content comprising a sensor for generating a sequence of frames where each frame in the sequence of frames comprises content representing a scene and a digital processor, coupled to the sensor, for performing scene content analysis and for establishing a window defining a number of input frames from the sensor and processed output frames, and for aligning and combining the number of frames in the window to form an output frame, wherein sensor parameters and frame combination parameters are adjusted based on scene content.

Abstract: The present invention provides a method and a system for high performance image signal processing of continuous images in real time. The system comprising a focal plane array for generating continuous source image frames in real time. The focal plane array divided logically into blocks of sub-frames. The system also comprising an analog to digital converter (ADC) layer having an array of ADC elements for converting the source image frames into a digital data. The system further comprising a digital processor layer having an array of processing elements for processing the digital data and an interconnecting layer for connecting each one of the ADC elements and the digital processing elements substantially vertically to the focal plane and substantially parallel to one another. The processing comprising reducing image motion blur, increasing image dynamic range, increasing image depth of field and obtaining features of the images.

Abstract: A method for making a poly-phase field winding for a slotless stator includes: forming the first coil group by winding an insulated wire for each coil winding in a first direction around a mandrel; axially shifting along the mandrel the insulated wire from a trailing edge of each coil winding a distance substantially equal to one half of twice the number of coil groups multiplied by the number of coil windings minus one times the width of one of the completed windings to position the wires at a leading edge of each of coil winding in the second coil group; forming the second coil group by winding the insulated wire for each coil winding in the first direction; removing the mandrel from the wound coil groups; collapsing the wound coil groups to a single layer web, and wrapping the single layer web into a cylinder to form the field winding.

Abstract: A device for the detection of an open and unattended closure of an enclosure to prevent theft comprises a detector adapted to detect if the closure is open and a detector adapted to detect if the closure is unattended, the detectors being operably connected to an effector adapted to alert a user to the open and unattended condition of the closure.

Abstract: An insulator for a stator assembly includes at least a first insulator adapted to be mounted to the stator core and structured to insulate the stator core from the coils. The at least one insulator includes structure to perform at least one additional function. For example, the structure may include a support member to support and/or locate the PCBA on the stator core, a wire guide to guide cross-over wires that form a connection between coils, and/or positioning structure to precisely position the PCBA with respect to the coils.

Abstract: An image article comprises a substrate having a security image coated on at least a portion thereof, which security image effects less than 50% reflectance of radiation of a wavelength between 800 and 900 nm, wherein the security image comprises a defined infrared-absorbing compound, for example Pigment Green 8, wherein said infrared-absorbing compound does not create a strongly coloured security image.

Abstract: A blower includes a housing including an inlet and an outlet, a bearing-housing structure provided to the housing and adapted to rotatably support a rotor, a motor provided to the bearing-housing structure and adapted to drive the rotor, and an impeller provided to the rotor. The bearing-housing structure includes a bearing shaft having a bearing surface that rotatably supports the rotor. The bearing shaft provides only a single bearing of the non-ball bearing type for the rotor.

Abstract: An insulator for a stator assembly includes at least a first insulator adapted to be mounted to the stator core and structured to insulate the stator core from the coils. The at least one insulator includes structure to perform at least one additional function. For example, the structure may include a support member to support and/or locate the PCBA on the stator core, a wire guide to guide cross-over wires that form a connection between coils, and/or positioning structure to precisely position the PCBA with respect to the coils.

Abstract: An insulator for a stator assembly includes at least a first insulator adapted to be mounted to the stator core and structured to insulate the stator core from the coils. The at least one insulator includes structure to perform at least one additional function. For example, the structure may include a support member to support and/or locate the PCBA on the stator core, a wire guide to guide cross-over wires that form a connection between coils, and/or positioning structure to precisely position the PCBA with respect to the coils.