Abstract: Provided is a connector assembly for optically connecting one or more optical fibers and an array of vertical coupling elements of a photonic integrated circuit (PIC). In various embodiments, the connector assembly is constructed to independently optically scale some feature sizes, such as, for example, the transverse mode size, the array size, the array geometry, and/or various incidence angles, the optical scaling being performed, e.g., from a fiber end face plane to a connector-mating plane and further to a PIC coupling plane. In some embodiments, the connector assembly may support a polarization (de)multiplexing functionality.

Abstract: The invention provides a light generating device (1000) comprising (i) a tubular enclosure (100) and (ii) a plurality of light sources (200) configured to generate light source light (201) configured within the tubular enclosure (100), wherein the light sources (200) comprise solid state light sources, wherein the enclosure (100) comprises an enclosure material (300) that is transmissive for at least part of the light source light (201), wherein the enclosure material (300) comprises polymeric foam material (310), wherein the polymeric foam material (310) has a volume fraction of gas voids (320) relative to the total volume of the polymeric foam material (310) including the gas voids (320) selected from the range of 10-95 vol. %, wherein the tubular enclosure (100) has a tube length (L1) of at least 400 mm and a wall thickness (w1) selected from the range of 0.5-6 mm.

Abstract: A system includes a housing having a front panel, a substrate that is positioned at a distance from the front panel, and a data processor mounted on the substrate. The system includes a pluggable module having an optical module, at least one first optical connector, a first fiber optic cable optically coupled between the optical module and the first optical connector, and a fiber guide positioned between the optical module and the first optical connector and provides mechanical support for the optical module and the first optical connector. The optical module receives optical signals from the first optical connector and generates electrical signals based on the received optical signals, and the electrical signals are transmitted to the data processor. The pluggable module has a shape that enables the pluggable module to pass through an opening in the front panel to enable the optical module to be coupled to the substrate.

Abstract: A method of assembling an optical device including: providing a photonic integrated circuit including a plurality of vertical-coupling elements disposed along a main surface of the photonic integrated circuit; attaching an optical subassembly to the photonic integrated circuit; removably connecting a fiber connector to a ferrule frame, in which the fiber connector is attached to an array of optical fibers; aligning the ferrule frame to the optical subassembly using an active alignment process; and securely connecting the ferrule frame to the optical subassembly after the active alignment process.

Abstract: Systems and methods are described for receiving a plurality of input images, a plurality of depth images, and a plurality of view parameters for generating a virtual view of a target subject. The systems and methods may generate a plurality of warped images based on the plurality of input images, the plurality of view parameters, and at least one of the plurality of depth images. In response to providing the plurality of depth images, the plurality of view parameters, and the plurality of warped images to a neural network, the systems and methods may receive, from the neural network, blending weights for assigning color to pixels of the virtual view of the target subject and may generate, based on the blending weights and the virtual view, a synthesized image according to the view parameters.

Abstract: A light emitting device (1) comprising at least one LED filament (2) comprising a flexible substrate (3) and a plurality of LED light sources (4) arranged on the flexible substrate (3), and an encapsulation (5a, 5b) encapsulating the plurality of LED light sources (4) and at least a part of one side of the flexible substrate (3), where the at least one LED filament (2) comprises at least one knot (6) in the form of intentional complication in cordage of the at least one LED filament (2), and where the intentional complication in cordage is any one of a fastening made by looping the at least one LED filament (2) on itself or together with a further LED filament and tightening it, and an intentional complication in cordage in which the at least one LED filament (2) is interlaced with at least one further LED filament at right angles to one another.

Abstract: The present application provides inter alia a fusion protein comprising a polypeptide wherein the polypeptide consists of a fragment of invariant chain which is operably linked to an antigenic sequence and wherein the fragment of invariant chain consists of a portion of residues 17-97 of SEQ ID NO: 1, wherein the portion comprises at least 5 contiguous residues from residues 77-92 of SEQ ID NO: 1.

Abstract: The invention relates to a harvesting device for harvesting fruit hanging from a plant, comprising a frame displaceable in a transport direction, at least one container displaceable relative to the frame in a direction of extension substantially transversely of the transport direction; and at least one catcher mounted on the at least one container, wherein the at least one brush comprises an arm extending substantially in the direction of extension from the container, and a number of bristles which are attached to the arm and extend substantially parallel to the transport direction. The invention also relates to a method for harvesting such fruit, wherein use is made of such a harvesting device.

Abstract: An apparatus includes baseband processing circuitry configured to generate a baseband signal that is transmitted to a first network element and a second network element, and an optical power supply configured to generate a first optical signal and a second optical signal, transmit the first optical signal to the first network element, and transmit the second optical signal to the second network element. The first optical signal and the second optical signal include information that enables synchronization of the first and second network elements.

Abstract: An apparatus includes a fiber-optic connector configured to be connected between one or more optical fibers having a plurality of fiber cores and a photonic integrated circuit including a plurality of vertical-coupling elements disposed along a main surface of the photonic integrated circuit. The fiber-optic connector includes a polarization beam splitter and a patterned birefringent plate. The polarization beam splitter is configured to split an incident light beam from a corresponding fiber core into a first beam having a first polarization and a second beam having a second polarization different from the first polarization. The patterned birefringent plate includes a first region and a second region, the first region has a first optical birefringence, the second region has a second optical birefringence that is different from the first optical birefringence.

Abstract: An electrical connector assembly (1) comprising a connector housing (5), a ceiling holder (3) and a cooling body (4), which ceiling holder (3) is provided between the connector housing (5) and the cooling body (4). The connector housing (5) comprises at least one clip lock mechanism (13, 14) with a resilient locking arm 15 which is provided with a first and a second clip (18, 19). Further the at least one clip lock mechanism (13, 14) comprises at least a first clip arm (21) which is provided with a first abutment protrusion (25) and a second abutment protrusion (26), respectively. The ceiling holder (3) may be manufactured of a number of materials, and depending of the chosen material, the thickness of the ceiling holder may differ.

Abstract: A distributed data processing system includes a first data processing system and a second data processing system. The first data processing system includes a first housing, a first data processor, and a first optical module that is configured to convert output electrical signals from the first data processor to output optical signals that are provided to a first optical fiber cable. The second data processing system includes a second housing, a second data processor, and a second optical module that is configured to convert output electrical signals from the second data processor to output optical signals that are provided to a second optical fiber cable. An optical power supply includes at least one laser that is configured to provide a first light source to the first optical module through a first optical link and to provide a second light source to the second optical module through a second optical link.

Abstract: An apparatus includes a rackmount device, in which the rackmount device includes a housing configured to be installed in a server rack, in which the housing has a width in a range from 16 to 20 inches and a height in a range from 1 to 12 inches, the housing includes a front panel, a rear panel, and a bottom surface. The rackmount device includes a first circuit board or substrate having a first surface that defines a length and a width of the first circuit board or substrate, in which the first circuit board or substrate is positioned relative to the housing such that the first surface of the first circuit board or substrate is at an angle relative to the bottom surface of the housing, and the angle is in a range from 45° to 90°.

Abstract: A harvesting device for harvesting fruit hanging from a plant, includes a frame which is displaceable in a transport direction and carries a loop-like conveyor track which can be driven in circular manner, and at least one harvesting bin connected to the conveyor track. The conveyor track lies in a plane which is substantially parallel to the transport direction and which lies at a first acute angle to the horizon in a direction transversely of the transport direction during normal use of the harvesting device. A method for harvesting fruit hanging from a plant, wherein the harvesting device is used.

Abstract: An apparatus includes: at least one of a circuit board or a substrate; and a first structure attached to the at least one of a circuit board or a substrate. The first structure is configured to enable an optical module with connector to be removably coupled to the first structure, and the optical module with connector is configured to enable an optical fiber connector to be removably coupled to the optical module with connector.

Abstract: There is disclosed alighting device (8) comprising: at least one light-emitting filament comprising (12) a plurality of solid-state light sources (14); and an elongated reflector (9) arranged to reflect light emitted by the light-emitting filament (12), wherein the reflector (9) has a longitudinal groove (11) in which the light-emitting filament (12) is arranged such that the reflector (9) and the at least one light-emitting filament (12) extend longitudinally along a common path, and wherein said path is curved in three dimensions. A light bulb (5) comprising the lighting device (8) and a luminaire (1) comprising the lighting device (8) are also disclosed. The lighting device (8) can be produced cost-efficiently and adapted to conform well to a predetermined emission pattern.

Abstract: Provided is a connector assembly for optically connecting one or more optical fibers and an array of vertical coupling elements of a photonic integrated circuit (PIC). In various embodiments, the connector assembly is constructed to independently optically scale some feature sizes, such as, for example, the transverse mode size, the array size, the array geometry, and/or various incidence angles, the optical scaling being performed, e.g., from a fiber end face plane to a connector-mating plane and further to a PIC coupling plane. In some embodiments, the connector assembly may support a polarization (de)multiplexing functionality.

Abstract: The present invention relates to duocarmycin-containing antibody-drug conjugates (ADCs) for use in the treatment of human solid tumours and haematological malignancies expressing HER2, in particular breast cancer, gastric cancer, bladder cancer, ovarian cancer, lung cancer, prostate cancer, pancreatic cancer, colorectal cancer, head and neck squamous cell cancer or osteosarcoma, and acute lymphoblastic leukaemia. In particular, the present invention relates to duocarmycin-containing ADCs for use in the treatment of human solid tumours with HER2 IHC 2+ or 1+ and HER2 FISH negative tissue status. Advantageously, the present invention relates to duocarmycin-containing ADCs for use in the treatment of triple negative breast cancer (TNBC).

Abstract: A WNT5A peptide or derivatives thereof in combination with one or more checkpoint inhibitors for use in treatment of cancer in a subject in need thereof. Furthermore, WNT5A peptides or derivatives thereof may be used in treatment of cancer in a subject, wherein the subject is responsive to immune checkpoint inhibitors.

Abstract: The invention provides nucleotide sequences and amino acid sequences of the Dip gene as well as (functional) homologues, fragments and variants thereof, which provides diplospory as a part of apomixis. Also diplospory plants and methods for making these are provided, as are methods of using these, and methods of making apomictic seed.