Abstract: The invention provides a lighting module for use in a reflector which comprises at least one first light source emitting first light having a first light distribution with a first main direction and at least one second light source emitting second light having a second light distribution with a second main direction opposite to the first main direction. A base connects the lighting module to a luminaire socket. The base has a longitudinal axis extending from the base. The first light source is positioned on the longitudinal axis and the second light source is positioned at a non-zero distance to the longitudinal axis. The first main direction and the second main direction are substantially perpendicular with respect to the longitudinal axis.

Abstract: A magnetic coupling assembly for coupling of a first rotary shaft and a second rotary shaft. The magnetic coupling assembly includes a first and second rotary hub, a sleeve, coaxial with the first rotary hub and arranged to be rotatable with respect to the first rotary hub, a first and second displacement element threadingly connected to the sleeve, and a first and a second rotatable inductor rotor arranged to co-rotate with the rotation of the first rotary hub. The first and second rotatable inductor rotors are connected to the first and second displacement element, respectively, and rotatable central magnet rotor. The sleeve includes threaded outer surfaces of opposite threading engaged by the first and second displacement elements so as to displace the first and second displacement elements in opposite directions.

Abstract: It was found that plants with loss of functional Msi2 protein due to a nucleotide polymorphism resulting in the introduction of a premature stop codon in the Msi2 protein, are able to induce haploid offspring after a cross to or with a wild type plant comprising a functional Msi2 protein. The invention relates to generation of haploid and doubled haploid plants.

Abstract: A retrofit light bulb (1) is disclosed. The retrofit light bulb (1) comprises a substantially flat heat spreader (2) having an opening (5); first and second cover members (7, 8) sandwiching the heat spreader (2), each cover member (7, 8) having a protruding portion (9, 10) directed away from the heat spreader (2) and aligned with the opening (5), the two protruding portion (9, 10) together forming a compartment (11); and one or more solid state lighting devices (18) mounted on a carrier (19) arranged in said compartment (11), in thermal contact with the heat spreader (2), wherein said one or more solid state lighting devices (18) are arranged so that each protruding portion (9, 10) receives light directly from each solid state lighting device (18). The compartment thus forms a single light mixing chamber in which light emitted by all of the SSL devices is mixed.

Abstract: A method for manufacturing a rotationally adjustable lamp (1) is disclosed. The method comprises: molding a shell (6) having a guiding slot (7a); providing a base (2) configured to receive the shell (6) and connect to a lamp socket; inserting the shell (6) into the base (2) so as to enclose the guiding slot (7a) by the base (2); and forming in the base (2), when the shell (6) is inserted into the base (2), a notch (5) protruding into the guiding slot (7a), the notch (5) being movable along the guiding slot (7a) so as to allow for the shell (6) to be rotated relative to the base (2).

Abstract: A lithographic apparatus is disclosed that includes a projection system, and a liquid confinement structure configured to at least partly confine immersion liquid to an immersion space defined by the projection system, the liquid confinement structure and a substrate and/or substrate table. Measures are taken in the lithographic apparatus, for example, to reduce the effect of droplets on the final element of the projection system or to substantially avoid such droplet formation.

Abstract: A lighting device comprising at least one light source (4) adapted for, in operation, emitting light, a heat sink element (3) comprising a first part (31) on which the at least one light source is arranged and a second part (32), the second part comprising a plurality of ribs (341, 342, 343, 344) extending from the first part, and a cover element (2) comprising an outer surface (21) adapted for forming a light exit surface of the lighting device, the cover element (2) comprising a first plurality of grooves (231, 232, 233) comprising a V-shaped cross-section and being provided in the outer surface of the cover element, the cover element being arranged such as to extend over the heat sink element in such a way that the first plurality of grooves extends over the plurality of ribs of the second part of the heat sink element.

Abstract: The invention provides a lighting module for use in a reflector which comprises at least one first light source emitting first light having a first light distribution with a first main direction and at least one second light source emitting second light having a second light distribution with a second main direction opposite to the first main direction. A base connects the lighting module to a luminaire socket. The base has a longitudinal axis extending from the base. The first light source is positioned on the longitudinal axis and the second light source is positioned at a non-zero distance to the longitudinal axis. The first main direction and the second main direction are substantially perpendicular with respect to the longitudinal axis.

Abstract: The present invention relates to a method for obtaining rubber from rubber-containing plant material, the method comprising the steps of subjecting a composition comprising rubber-containing plant material and a fermentation culture to conditions allowing anaerobic fermentation, wherein the composition preferably has a water content of less than 95 wt. %. The fermentation preferably does not involve movement of the rubber-containing plant material (or parts thereof), and preferably the fermentation is performed in the absence of oxygen ventilation. Additionally, it is preferred that the fermentation culture is cycled through the composition by percolation. A further step of the method involves obtaining the rubber from the composition.

Abstract: To enable better sharing and preservation of immersive experiences, a graphics system reconstructs a three-dimensional scene from a set of images of the scene taken from different vantage points. The system processes each image to extract depth information therefrom and then stitches the images (both color and depth information) into a multi-layered panorama that includes at least front and back surface layers. The front and back surface layers are then merged to remove redundancies and create connections between neighboring pixels that are likely to represent the same object, while removing connections between neighboring pixels that are not. The resulting layered panorama with depth information can be rendered using a virtual reality (VR) system, a mobile device, or other computing and display platforms using standard rendering techniques, to enable three-dimensional viewing of the scene.

Abstract: The present invention relates to duocarmycin-containing antibody-drug conjugates (ADCs) for use in the treatment of human solid tumors expressing HER2, wherein the human solid tumor expressing HER2 is endometrial cancer, in particular uterine serous carcinoma (USC). In particular, the present invention relates to duocarmycin-containing ADCs for use in the treatment of endometrial cancer, notably USC, with HER2 IHC 2? or 1+ and HER2 FISH negative tumor tissue status.

Abstract: A lithographic apparatus includes a projection system configured to project a patterned radiation beam onto a target portion of a substrate. The projection system has a final element. The apparatus also includes a barrier member surrounding a space between the projection system and, in use, the substrate, to define in part with the final element a reservoir for liquid. The barrier member is spaced from the final element to define a gap therebetween. The apparatus further includes a deformable seal between a radially outer surface of the final element and a radially outer surface of the barrier member. The deformable seal is configured to substantially prevent a gas from flowing past the seal towards or away from the reservoir of liquid.

Abstract: The present invention relates to a method for obtaining Taraxacum plants of considerable size and substantial rubber content, preferably by providing Taraxacum plants having a relatively large genome size and/or having a specific percentage of Taraxacum koksaghyz (TKS) derived genes and a specific percentage of Taraxacum officinale (TO) derived genes; selecting these plants for the presence or absence of certain markers; and subsequently selecting the plants on plant size, and on genome size.

Abstract: The invention provides nucleotide sequences and amino acid sequences of the Dipgene as well as (functional) homologues, fragments and variants thereof, which provides diplospory as a part of apomixis. Also diplospory plants and methods for making these are provided, as are methods of using these, and methods of making apomictic seed.

Abstract: To enable better sharing and preservation of immersive experiences, a graphics system reconstructs a three-dimensional scene from a set of images of the scene taken from different vantage points. The system processes each image to extract depth information therefrom and then stitches the images (both color and depth information) into a multi-layered panorama that includes at least front and back surface layers. The front and back surface layers are then merged to remove redundancies and create connections between neighboring pixels that are likely to represent the same object, while removing connections between neighboring pixels that are not. The resulting layered panorama with depth information can be rendered using a virtual reality (VR) system, a mobile device, or other computing and display platforms using standard rendering techniques, to enable three-dimensional viewing of the scene.

Abstract: To enable better sharing and preservation of immersive experiences, a graphics system reconstructs a three-dimensional scene from a set of images of the scene taken from different vantage points. The system processes each image to extract depth information therefrom and then stitches the images (both color and depth information) into a multi-layered panorama that includes at least front and back surface layers. The front and back surface layers are then merged to remove redundancies and create connections between neighboring pixels that are likely to represent the same object, while removing connections between neighboring pixels that are not. The resulting layered panorama with depth information can be rendered using a virtual reality (VR) system, a mobile device, or other computing and display platforms using standard rendering techniques, to enable three-dimensional viewing of the scene.

Abstract: The present invention relates to a flat lighting device (1) comprising a carrier (2) including a thermally conductive layer (7), at least one solid state light source (3) arranged on a front side of the carrier (2), and an electrically insulating cover member (5a, 5b) in thermal contact with said front side and a back side opposite said front side. The cover member (5a, 5b) is adapted to transfer heat from said carrier (2) out of the lighting device. The cover member (5a, 5b) comprises an optical structure (4) arranged on the carrier (2) in front of the at least one light source (3) and adapted to direct the light emitted by the at least one solid state light source (3).

Abstract: An illumination device includes a carrier, at least two light sources mounted on a first side of a carrier, and an envelope at least partially enclosing light sources and the carrier. At least one of the light sources is mounted on a portion of the carrier and at least another one of the light sources is mounted on a different portion of the carrier, and the carrier is folded such that the second side of the first portion of the carrier at least partially faces the second side of the second portion of the carrier.

Abstract: The present invention relates to duocarmycin-containing antibody-drug conjugates (ADCs) for use in the treatment of human solid tumours and haematological malignancies expressing HER2, in particular breast cancer, gastric cancer, bladder cancer, ovarian cancer, lung cancer, prostate cancer, pancreatic cancer, colorectal cancer, head and neck squamous cell cancer or osteosarcoma, and acute lymphoblastic leukaemia. In particular, the present invention relates to duocarmycin-containing ADCs for use in the treatment of human solid tumours with HER2 IHC 2+ or 1+ and HER2 FISH negative tissue status. Advantageously, the present invention relates to duocarmycin-containing ADCs for use in the treatment of triple negative breast cancer (TNBC).

Abstract: A lighting device (100, 400) comprising a cover having an inside (128) and an outside (129). The cover defines a light emitting portion (112), a driver circuitry chamber (114), a transition portion (113) between the light emitting portion (112) and the driver circuitry chamber (114), and a cap portion (115) at the opposite end of the driver circuitry chamber (114) compared to the transition portion (113). The lighting device (100, 400) further comprises a carrier (104) arranged in the light emitting portion (112) and solid state light sources (106) mounted on the carrier (106). The lighting device (100, 400) further comprises a thermally conductive inlay (120, 121, 420, 421) in thermal contact with the cover and arranged along the inside of the cover for transferring heat from the light emitting portion (112) to at least one of the transition portion (113), the driver circuitry chamber (114) and the cap portion (115).