Abstract: Certain compounds, or pharmaceutically acceptable salts or prodrugs thereof, are provided herein. Also provided are pharmaceutical compositions comprising at least one compound, or pharmaceutically acceptable salt or prodrug thereof, described herein and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of KMO activity are described, which comprise administering to such patients an amount of at least one compound, or pharmaceutically acceptable salt or prodrug thereof, described herein effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include neurodegenerative disorders such as Huntington's disease.

Abstract: A system and method for mitigating security vulnerabilities of a computer network by detecting a management status of an endpoint computing device attempting to authenticate to one or more computing resources accessible via the computer network includes: detecting an authentication attempt by the endpoint computing device to the computer network; during the authentication attempt, collecting management status indicia from the endpoint computing device, wherein the management status indicia comprise data used to determine a management status of the endpoint computing device; using the management status indicia to identify the management status of the endpoint computing device and identifying the management status of the endpoint computing device; and controlling access to the computer network based on (a) whether the authentication attempt by the endpoint computing device is successful and (b) the identified management status of the endpoint computing device.

Abstract: Polymeric blends having improved flame retardance properties and good ductility at low temperatures are disclosed. The blend is formed from (A) a photoactive additive that is a cross-linkable polycarbonate resin containing a photoactive group derived from a dihydroxybenzophenone; and (B) a polymer resin which is different from the photoactive additive. The additive can be a compound, oligomer, or polymer. When exposed to ultraviolet light, crosslinking will occur between the photoactive additive and the polymer resin, enhancing the chemical resistance and flame retardance while maintaining ductility.

Abstract: A valve may comprise a plug receivable by a seat wherein both the plug and seat comprise superhard material. The valve may be designed and operated in such a way so as not to fracture the superhard material as the plug is received by the seat. Specifically, the valve may comprise a magnetic core translatable within at least one solenoid. Kinetic energy from the translating magnetic core may be transmitted to the plug when the magnetic core impacts an anvil causing the plug to move relative to the seat. The plug may be moved incrementally relative to the seat by a plurality of impacts of the magnetic core.

Abstract: A valve may use fluid pressure to provide bistability to the valve by creating two regions that experience different pressures on one surface of the valve. The two regions may change in size relative to each other as the surface approaches another surface thus changing the combined pressures experienced by the regions. A velocity of fluid flow may increase as it passes one of the regions thus reducing pressure to that region. Additionally, an eddy current may form adjacent another one of the regions thus reducing pressure to that region. Consequently, the valve may be urged open when open and urged closed when closed.

Abstract: Certain chemical entities are provided herein. Also provided are pharmaceutical compositions comprising at least one chemical entity and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of KMO activity are described, which comprise administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include neurodegenerative disorders such as Huntington's disease. Also described are methods of treatment include administering at least one chemical entity as a single active agent or administering at least one chemical entity in combination with one or more other therapeutic agents. Also provided are methods for screening compounds capable of inhibiting KMO activity.

Abstract: Processes for increasing the chemical resistance of a surface of a formed article are disclosed. The formed article is produced from a polymeric composition comprising a photoactive additive containing photoactive groups derived from a monofunctional benzophenone. The surface of the formed article is then exposed to ultraviolet light to cause crosslinking of the photoactive additive and produce a crosslinked surface. The crosslinking enhances the chemical resistance of the surface. Various means for controlling the depth of the crosslinking are also discussed.

Abstract: A downhole drill bit, of the type used to bore into the earth when searching for or extracting subterranean resources, may comprise a working face opposite an attachment end and an opening passing from the attachment end through to the working face. A protrusion on one end of a bottom hole assembly may extend through the opening and be exposed at the working face when the drill bit is attached to the end of the bottom hole assembly. In various embodiments the exposed portion of the protrusion may house conduits or nozzles for handling fluids; sensors, transmitters or wires for handling electrical signals; or mechanical hammers, motors or cutters for degrading an earthen formation. In this way, the protrusion may bring such elements from the bottom hole assembly to the working face of the drill bit.

Abstract: A system and method for mitigating security vulnerabilities of a computer network by detecting a management status of an endpoint computing device attempting to authenticate to one or more computing resources accessible via the computer network includes: detecting an authentication attempt by the endpoint computing device to the computer network; during the authentication attempt, collecting management status indicia from the endpoint computing device, wherein the management status indicia comprise data used to determine a management status of the endpoint computing device; using the management status indicia to identify the management status of the endpoint computing device and identifying the management status of the endpoint computing device; and controlling access to the computer network based on (a) whether the authentication attempt by the endpoint computing device is successful and (b) the identified management status of the endpoint computing device.

Abstract: In one example, a shell includes walls that collectively define an interior space of the shell, the interior space sized and configured to receive heat generating equipment. An internal heat exchanger disposed within the interior space is arranged for thermal communication with heat generating equipment when heat generating equipment is located in the interior space. Additionally, an external heat exchanger is located outside of the shell and arranged for fluid communication with the internal heat exchanger. Finally, a prime mover is provided that is in fluid communication with the internal heat exchanger and the external heat exchanger, and the prime mover is operable to circulate a flow of coolant through the internal heat exchanger and the external heat exchanger.

Abstract: Certain compounds, or pharmaceutically acceptable salts or prodrugs thereof, are provided herein. Also provided are pharmaceutical compositions comprising at least one compound, or pharmaceutically acceptable salt or prodrug thereof, described herein and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of KMO activity are described, which comprise administering to such patients an amount of at least one compound, or pharmaceutically acceptable salt or prodrug thereof, described herein effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include neurodegenerative disorders such as Huntington's disease.

Abstract: Various examples of systems, methods, and programs embodied in computer-readable mediums are provided for fingerprint liveness detection. Fingerprint liveness may be determined by evaluating pixels of a fingerprint image to identify pores along a ridge segment of the fingerprint image. A circular derivative operator can be used to identify the pores. Liveness of the fingerprint can be determined based upon features of the identified pores.

Abstract: In one example, a portion of a shell includes a shell wall portion that has an interior wall portion and an exterior wall portion located near the interior wall portion. In addition, fluid passageways are disposed between the interior wall portion and the exterior wall portion. One or more of the fluid passageways are defined in part by one or both of the interior wall portion and the exterior wall portion. The fluid passageways form part of heat exchanger that is integrated in the shell.

Abstract: Devices and methods for receiving a data file in a communication system. In one embodiment, the wireless communication device includes a transceiver, a memory, and an electronic processor. The transceiver is configured to send and receive data over a wireless communication network. The electronic processor is electrically coupled to the transceiver and the memory and configured to receive, with the transceiver, a first seed, a sequence of blocks, and a subsequent seed, cause the memory to save the sequence of blocks in the memory, and determine whether the subsequent seed is aligned with the first seed. When the subsequent seed is not aligned with the first seed, the electronic processor is configured to cause the memory to delete the sequence of blocks. When the subsequent seed is aligned with the first seed, the electronic processor is configured to cause the memory to maintain the sequence of blocks.

Abstract: Processes for increasing the chemical resistance of a surface of a formed article are disclosed. The formed article is produced from a polymeric composition comprising a photoactive additive containing photoactive groups derived from a monofunctional benzophenone. The surface of the formed article is then exposed to ultraviolet light to cause crosslinking of the photoactive additive and produce a crosslinked surface. The crosslinking enhances the chemical resistance of the surface. Various means for controlling the depth of the crosslinking are also discussed.