Patents by Inventor Peter Klein

Peter Klein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydroxyl-containing compounds
    Publication number: 20030207901
    Abstract: Disclosed are therapeutic compounds having the formula:
    Type: Application
    Filed: May 14, 2003
    Publication date: November 6, 2003
    Applicant: Cell Therapeutics, Inc.
    Inventors: Gail E. Underiner, David Porubek, J. Peter Klein, Paul Woodson, Stephen J. Klaus, Anil M. Kumar, John Tulinsky
  • Transdermal therapeutical system with a reduced tendency of the active substance to crystallize
    Publication number: 20030175330
    Abstract: A transdermal therapeutic system in patch form for the controlled delivery of active substances to the human or animal skin comprises a backing layer, an active substance-containing reservoir attached thereto and a detachable protective layer, is characterized in that the active substance-containing reservoir contains as main components thereof at least one film former as well as at least one polymer which prevents or suppresses the crystallisation of the active substance or active substances.
    Type: Application
    Filed: May 5, 2003
    Publication date: September 18, 2003
    Inventors: Reinhold Meconi, Robert-Peter Klein, Frank Seibertz
  • Tricyclic compounds and their uses
    Publication number: 20030162801
    Abstract: Novel tricyclic compounds are found to be useful for the treatment or prevention of symptoms or manifestations associated with diseases or disorders affected by cytokine intracellular signaling.
    Type: Application
    Filed: January 24, 2003
    Publication date: August 28, 2003
    Inventors: Baoqing Gong, J. Peter Klein, Michael Coon
  • Aryl triazines as LPAAT-SS inhibitors and uses thereof
    Publication number: 20030153570
    Abstract: The invention relates to aryl triazines and uses thereof, including to inhibit lysophosphatidic acid acyltransferase &bgr; (LPAAT-&bgr;) activity and/or proliferation of cells such as tumor cells.
    Type: Application
    Filed: October 30, 2002
    Publication date: August 14, 2003
    Applicant: Cell Therapeutics, Inc.
    Inventors: Rama Bhatt, Baoqing Gong, Feng Hong, Scott A. Jenkins, J. Peter Klein, Anil M. Kumar, John Tulinsky
  • Portable digital readout scale
    Patent number: 6600110
    Abstract: A portable scale is provided that includes a fulcrum, a balance beam pivotally mounted on the fulcrum, the balance beam supporting a load pan on one end and including an elongated portion having a measurement strip extending along the elongated portion of the balance beam. The portable scale includes a dynamic weight movable along the elongated portion of the balance beam. The dynamic weight includes a display unit on the elongated portion of the balance beam for detecting the location of the dynamic weight along the measurement strip, for electrically converting the location to a weight measurement, and for displaying the weight measurement. The portable scale may include luminescent material.
    Type: Grant
    Filed: October 1, 2001
    Date of Patent: July 29, 2003
    Assignee: Gram Precision
    Inventors: Mohan Thadani, Peter Klein
  • Tricyclic fused xanthine compounds and their uses
    Patent number: 6586429
    Abstract: Novel tricyclic compounds are found to be useful for the treatment or prevention of symptoms or manifestations associated with diseases or disorders affected by cytokine intracellular signaling. The compounds have the following formulas where R1, R2 and R3 are defined in the written description of the invention.
    Type: Grant
    Filed: November 29, 2000
    Date of Patent: July 1, 2003
    Assignee: Cell Therapeutics, Inc.
    Inventors: Baoqing Gong, J. Peter Klein, Michael Coon
  • LPAAT-beta inhibitors and uses thereof
    Publication number: 20030100557
    Abstract: The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase &bgr; (LPAAT-&bgr;) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT-&bgr; activity.
    Type: Application
    Filed: September 6, 2002
    Publication date: May 29, 2003
    Applicant: Cell Therapeutics, Inc.
    Inventors: Robert Finney, David Leung, J. Peter Klein, David M. Hollenback, Lynn Bonham, Scott A. Shaffer, Norina M. Tang, Thayer H. White, John Tulinsky, Baoqing Gong
  • Method of endovenous laser treatment
    Publication number: 20030078569
    Abstract: A method of endovenous laser treatment is disclosed. An introducer sheath 40 is introduced into a vein and an optical fibre 12 is introduced through the introducer sheath until a first marking 45 on the optical fibre 12 indicates that the distal end of the optical fibre 12 is substantially in alignment with the distal end of the introducer sheath 40. The introducer sheath 40 is then withdrawn relative to the optical fibre 12 until a second marking 46 on the optical fibre 12 indicates that the distal end of the optical fibre 12 extends a predetermined distance beyond the distal end of said introducer sheath 40. Laser radiation is passed down the optical fibre 12 so that laser radiation is delivered to the inner wall of the vein and the introducer sheath 40 together with the optical fibre 12 are withdrawn a certain distance along the vein.
    Type: Application
    Filed: June 14, 2002
    Publication date: April 24, 2003
    Applicant: Diomed Inc.
    Inventors: Tiziano Caldera, Robert Min, Peter Klein
  • Medical laser device
    Publication number: 20030078568
    Abstract: A medical laser device is disclosed comprising an optical fibre 12 having markings 45,46 which enable the optical fibre 12 to be accurately positioned relative to an introducer sheath 40. The introducer sheath 40 may also have graduated markings to enable the sheath 40 to be withdrawn at a controlled rate. A pulsed or continuous laser source may be provided.
    Type: Application
    Filed: June 14, 2002
    Publication date: April 24, 2003
    Applicant: Diomed Inc.
    Inventors: Tiziano Caldera, Robert Min, Peter Klein
  • Manufacture of polyglutamate-therapeutic agent conjugates
    Publication number: 20030054977
    Abstract: The invention provides new processes for preparing polyglutamic acid-therapeutic agent conjugates for clinical development and pharmaceutical use, and polyglutamic acid-therapeutic agent conjugates prepared by these processes.
    Type: Application
    Filed: July 18, 2002
    Publication date: March 20, 2003
    Applicant: Cell Therapeutics, Inc.
    Inventors: Anil Kumar, J. Peter Klein, Rama Bhatt, Edward Vawter
  • Method and apparatus for adjusting an internal combustion engine with variable valve timing
    Patent number: 6502545
    Abstract: A method for adjusting an internal combustion engine with variable valve timing wherein the current position of the accelerator pedal is associated with a set air mass and a set pressure. The set pressure is compared with a reference pressure and control of the set air mass takes place via the throttling device in the intake pipe when the pressure falls below the reference pressure, and control of the set air mass is carried out via the engine valves when the pressure exceeds the reference pressure.
    Type: Grant
    Filed: November 13, 2000
    Date of Patent: January 7, 2003
    Assignee: DaimlerChrysler AG
    Inventors: Thomas Ganser, Igor Gruden, Rainer Kessler, Peter Klein, Charles Robert Koch, Kurt Maute, Klaus Wunderlich
  • Conversion of modification D to modification A of doxazosin mesylate
    Patent number: 6500830
    Abstract: A process for preparing doxazosin mesylate in modification A which comprises dissolving doxazosin with methanesulfonic acid in methanol or a mixture of an aprotic, polar organic solvent and methanol, removing any turbidity from the resulting solution, and stirring the resulting clear solution until no further precipitate separates out, removing, washing with methanol, heating the precipitate in the moist state in ethanol and, after cooling, isolating the resulting product is described.
    Type: Grant
    Filed: July 3, 2000
    Date of Patent: December 31, 2002
    Assignee: Knoll Aktiengesellschaft
    Inventors: Peter Klein, Marco Thyes, Dieter Hix
  • Polyglutamic acid-camptothecin conjugates and methods of preparation
    Publication number: 20020183243
    Abstract: The invention provides polyglutamic acid-therapeutic agent conjugates and methods for their preparation and use.
    Type: Application
    Filed: January 22, 2002
    Publication date: December 5, 2002
    Applicant: Cell Therapeutics, Inc.
    Inventors: Rama Bhatt, Peter de Vries, J. Peter Klein, John Tulinsky, Robert A. Lewis, Jack W. Singer
  • Medicaments containing doxazosin mesylate of crystalline modification D
    Patent number: 6476033
    Abstract: Drugs comprising modification D of doxazosin mesylate are described. They are suitable for treating high blood pressure.
    Type: Grant
    Filed: September 18, 2001
    Date of Patent: November 5, 2002
    Assignee: Chemische Fabrik Berg GmbH
    Inventors: Marco Thyes, Heinz Einig, Peter Klein, Dieter Hix
  • Method of inhibiting interleukin-12 signaling
    Patent number: 6469017
    Abstract: A method for blocking IL-12 signaling by administration of the following compound: wherein, R1 is H, CH3, sulfate, phosphate, or salt thereof; R2 is alkyl (C1-12), alkoxyalkyl (C1-11), dialkoxyalkyl, CH2C6H5, —CH2-furan, biotin; and R3 is H, CH3 or CH2C6H5.
    Type: Grant
    Filed: January 16, 1998
    Date of Patent: October 22, 2002
    Assignee: Cell Therapeutics, Inc.
    Inventors: Stephen J. Klaus, J. Peter Klein, Anil M. Kumar
  • Method and system for compiling source code containing natural language instructions
    Patent number: 6453465
    Abstract: A system and method for compiling source code comprising natural language declarations, natural language method calls, and natural language control structures into computer-executable object code is disclosed. The system and method allow the compilation of source code containing both natural language and computer language into computer-executable object code. The system and method use a component database, containing components and associated natural language instructions, to select one or more components having an instruction declaration associated with the natural language instruction. A solution manager is used to resolve ambiguities inherent in the use of natural language instructions in the source code.
    Type: Grant
    Filed: November 22, 2000
    Date of Patent: September 17, 2002
    Inventor: Peter A. Klein
  • Benzoxazole LPAAT-B inhibitors and uses thereof
    Publication number: 20020107269
    Abstract: The invention relates to benzoxazoles and the use thereof to inhibit lysophosphatidic acid acyltransferase &bgr; (LPAAT-&bgr;) activity. The invention further relates to methods of treating cancer using said benzoxazoles. The invention also relates to methods for screening for LPAAT-&bgr; activity.
    Type: Application
    Filed: October 31, 2001
    Publication date: August 8, 2002
    Applicant: CELL THERAPEUTICS, INC.
    Inventors: Lynn Bonham, J. Peter Klein, Robert E. Finney, David M. Hollenback, Scott A. Shaffer, Norina M. Tang, Thayer H. White, David W. Leung
  • LPAAT-B inhibitors and uses thereof
    Publication number: 20020103195
    Abstract: The invention relates to triazines and the use thereof to inhibit lysophosphatidic acid acyltransferase &bgr; (LPAAT-&bgr;) activity. The invention further relates to methods of treating cancer using said triazines. The invention also relates to methods for screening for LPAAT-&bgr; activity.
    Type: Application
    Filed: October 31, 2001
    Publication date: August 1, 2002
    Applicant: CELL THERAPEUTICS,INC.
    Inventors: Lynn Bonham, J. Peter Klein, Robert E. Finney, David M. Hollenback, Scott A. Shaffer, Norina M. Tang, Thayer H. White, David W. Leung
  • TRICYCLIC FUSED XANTHINE COMPOUNDS AND THEIR USES
    Publication number: 20020103211
    Abstract: Novel tricyclic compounds are found to be useful for the treatment or prevention of symptoms or manifestations associated with diseases or disorders affected by cytokine intracellular signaling.
    Type: Application
    Filed: November 29, 2000
    Publication date: August 1, 2002
    Applicant: Cell Therapeutics, Inc.
    Inventors: Baoqing Gong, J. Peter Klein, Michael Coon
  • Arrangement for producing a vacuum in a motor vehicle system
    Patent number: 6412277
    Abstract: In an arrangement for producing a vacuum in a motor vehicle system including an internal combustion engine with an air intake system, a vacuum-operated power brake system for braking the vehicle and a fuel vapor adsorption system for collecting fuel vapors, a vacuum pump is provided which has a suction side in communication selectively with the vacuum operated power brake system and the fuel vapor adsorption system and a discharge side in communication with the air intake system of the internal combustion engine.
    Type: Grant
    Filed: January 12, 2001
    Date of Patent: July 2, 2002
    Assignee: DaimlerChrysler AG
    Inventors: Aurel Hagen, Peter Klein, Lothar Mauz, Arthur Pradt, Bernhard Schweizer, Klaus Wunderlich