Abstract: The present invention concerns a reusable surgical guide for osteosynthesis surgery, forming an aimer for guiding and inserting axial wires into bone portions; said guide comprises a grip constituted by a head extending at the upper end of a base, a trigger adapted to be displaced in a first slide formed in the head of the grip and whose distal end is provided with a through hole for the insertion of a wire, a blade secured to the distal end of the head of the grip, under the trigger, and a so-called aiming piece adapted to be displaced in a second slide formed in the base of the grip, said aiming piece comprising at the distal end thereof means for supporting at least one wire.

Abstract: The disclosure relates generally to bacteria that have been modified to metabolize a bile acid, pharmaceutical compositions including the bacteria, and methods of using the bacteria and pharmaceutical compositions to treat disorders associated with an elevated amount of bile acid, e.g., bile acid diarrhea.

Abstract: A reusable surgical guide for osteosynthesis surgery. for the insertion of wires into bone portions. and a method of using the same. The guide includes a grip including a head extending an end of a base, a blade secured to the head. a trigger that is displaceable in a first slide formed in the head, and an aiming piece that is displaceable in a second slide formed in the base. The trigger includes a guide element for insertion of a pull wire. and the aiming piece includes a means for supporting at least one positioning wire. The method includes retracting the trigger to move a first bone portion relative to a second bone portion; and inserting a first wire through the supporting means and into the first and second bone portions in a state in which the surgical guide and a draw wire holds relative positions of the bone portions.

Abstract: The present invention is related to a novel process for production of retinyl acetate in a host cell, particularly oleaginous yeast such as e.g. Yarrowia, wherein the product purity could be increased with reduction of unwanted side-products. Particularly, the novel process comprises fermentation in the presence of ethanol, such as e.g. in a fed-batch fermentation process. Such process is especially useful in a biotechnological process for production of vitamin A.

Abstract: The present invention is related to production of retinyl esters, such as in particular retinyl acetate, an important building block for production of vitamin A. The retinyl esters might be generated via enzymatic conversion of retinol which process includes the use of enzymes with acetyl-transferase (ATF) activity, thus acetylating retinol into retinol/retinyl acetate. Said process is particularly useful for biotechnological production of vitamin A.

Abstract: The present disclosure relates to ejector mechanisms and devices for generating a directed stream of droplets, as well as improved methods for delivering an ejected stream of droplets to a target. The device and methods may be useful for the delivery of fluid for ophthalmic, topical, oral, nasal, or pulmonary use, more particularly, for use in the delivery of ophthalmic fluid to the eye. Certain aspects of the disclosure relate to devices and methods for the delivery of a therapeutically effective low dosage volume medicament composition to a target, e.g., by controlling charge, droplet size and/or droplet deposit parameters of the medicament composition.

Abstract: An article of footwear includes an upper defining an interior void and a first cable movable in a tightening direction to move the upper into a tightened state and movable in a loosening direction to move the upper into a loosened state. The article of footwear also includes a tightening grip operable to be moved away from the upper in a first direction to move the first cable in the tightening direction and a cable lock operable in a locked state to restrict movement of the first cable in the loosening direction and operable in an unlocked state to permit movement of the first cable in the loosening direction. A release grip is operable to be moved away from the upper in a second direction to move the cable lock from the locked state to the unlocked state, whereby the release grip is separate from the tightening grip.

Abstract: A server for identifying and prioritizing IT security events associated with a network is caused to receive a dataset representing IT security events specific to one or more resources associated with the network, generate, by defined algorithms, individual scores for the IT security events, correlate each of the individual scores for the IT security events with the one or more resources, aggregate, for a resource of the one or more resources, each of the individual scores correlated with the resource into a security score specific to the resource, determine whether the security score exceeds a defined threshold, and in response to the security score exceeding the defined threshold, generate and transmit a security incident alert specific to the resource to a security operation center. Example servers, systems, apparatuses, methods, and non-transitory computer readable medium for identifying and prioritizing IT security events associated with a network are also disclosed.

Abstract: A sole structure for an article of footwear, the sole structure including a forefoot region and a heel region. The sole structure further includes a chassis plate, an outsole plate extending from the forefoot region to the heel region, the outsole plate including a recess disposed in a top surface, wherein the outsole plate is disposed below the chassis plate, and a cushioning element disposed within the recess.

Abstract: A sole structure for an article of footwear, the sole structure including a forefoot region and a heel region. The sole structure further includes a chassis plate, an outsole plate extending from the forefoot region to the heel region, the outsole plate including a recess disposed in a top surface, wherein the outsole plate is disposed below the chassis plate, and a cushioning element disposed within the recess.

Abstract: An article of footwear includes an upper defining an interior void and a first cable movable in a tightening direction to move the upper into a tightened state and movable in a loosening direction to move the upper into a loosened state. The article of footwear also includes a tightening grip operable to be moved away from the upper in a first direction to move the first cable in the tightening direction and a cable lock operable in a locked state to restrict movement of the first cable in the loosening direction and operable in an unlocked state to permit movement of the first cable in the loosening direction. A release grip is operable to be moved away from the upper in a second direction to move the cable lock from the locked state to the unlocked state, whereby the release grip is separate from the tightening grip.

Abstract: An in-line sterilization system including a caddie sized and shaped to releasably secure a container and a sterilization system for sterilizing the container using pulsed ultraviolet light. The sterilization system includes a first light source and a second light source positioned within an antechamber and forming a sterilization zone between the first and second light sources, each of the first and second light sources configured to transmit pulsed ultraviolet light into the sterilization zone. The sterilization system includes a transport system having a turntable. The perimeter region of the turntable is arranged to support the caddie upon receipt of the caddie within the antechamber and to move the caddie through the sterilization zone. The caddie and at least the perimeter region of the turntable are transparent to the ultraviolet light. Related systems, devices, compositions, and methods of use are provided.

Abstract: An article of footwear includes an upper defining an interior void and a first cable movable in a tightening direction to move the upper into a tightened state and movable in a loosening direction to move the upper into a loosened state. The article of footwear also includes a tightening grip operable to be moved away from the upper in a first direction to move the first cable in the tightening direction and a cable lock operable in a locked state to restrict movement of the first cable in the loosening direction and operable in an unlocked state to permit movement of the first cable in the loosening direction. A release grip is operable to be moved away from the upper in a second direction to move the cable lock from the locked state to the unlocked state, whereby the release grip is separate from the tightening grip.

Abstract: A lace-receiving assembly includes a substrate, a first sheet, and a lace guide. The substrate includes a first surface and a second surface opposite the first surface. The first sheet includes a third surface and a fourth surface opposite the third surface. The third surface is bonded to the first surface to define a channel extending between the substrate and the first sheet. The lace guide is disposed within the channel.

Abstract: The present invention concerns a reusable surgical guide for osteosynthesis surgery, forming an aimer for guiding and inserting axial wires into bone portions; said guide comprises a grip constituted by a head extending at the upper end of a base, a trigger adapted to be displaced in a first slide formed in the head of the grip and whose distal end is provided with a through hole for the insertion of a wire, a blade secured to the distal end of the head of the grip, under the trigger, and a so-called aiming piece adapted to be displaced in a second slide formed in the base of the grip, said aiming piece comprising at the distal end thereof means for supporting at least one wire.

Abstract: A method for network hardware table management includes: obtaining, by a network device table manager of a network device, a first feature table entry of a first feature table, where the first feature table entry comprises a first prefix and a first action to take for a first feature; obtaining, by the network device table manager, a second feature table entry of a second feature table, where the second feature table entry comprises a second prefix and a second action to take for a second feature; making a first determination that the first prefix and the second prefix include a common portion and that the common portion is an entirety of each of the first and second prefixes; and in response to the first determination, adding a combined feature table entry to a combined feature table.

Abstract: An article of footwear includes a sole structure. The sole structure includes a plate having a first surface defining a ground-contacting surface and a second surface disposed on an opposite side of the plate than the first surface. The plate includes a recess formed into the second surface, which is defined by a first sidewall, a second sidewall, and a bottom wall. The plate includes a first channel, a second channel, a third channel, and a fourth channel each extending from and in fluid communication with the recess. The first channel, a second channel, a third channel, and a fourth channel cooperate with the recess to form a substantially H-shaped structure in the second surface. The article of footwear also includes a cable lock disposed within the recess. The cable lock includes a housing disposed in the recess and a plurality of cable elements received within the channels.

Abstract: The present disclosure relates to ejector mechanisms and devices for generating a directed stream of droplets, as well as improved methods for delivering an ejected stream of droplets to a target. The device and methods may be useful for the delivery of fluid for ophthalmic, topical, oral, nasal, or pulmonary use, more particularly, for use in the delivery of ophthalmic fluid to the eye. Certain aspects of the disclosure relate to devices and methods for the delivery of a therapeutically effective low dosage volume medicament composition to a target, e.g., by controlling charge, droplet size and/or droplet deposit parameters of the medicament composition.

Abstract: A lace-receiving assembly includes a substrate, a first sheet, and a lace guide. The substrate includes a first surface and a second surface opposite the first surface. The first sheet includes a third surface and a fourth surface opposite the third surface. The third surface is bonded to the first surface to define a channel extending between the substrate and the first sheet. The lace guide is disposed within the channel.

Abstract: Methods, systems, and computer readable mediums for network hardware table management including obtaining, by a network device table manager of a network device, a first feature table entry published by a first feature; obtaining, by the network device table manager, a second feature table entry published by a second feature; making a first determination that the first feature table entry and the second table feature entry each comprise a common prefix; and based on the first determination, adding a first combined feature table entry to a combined feature table, the first combined feature table entry comprising the common prefix, a first feature action of the first feature table entry and a second feature action of the second feature table entry.