Patents by Inventor Peter Laurence

Peter Laurence has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090210182
    Abstract: An opacity process for paint, including generating paint color data representing a paint color, based on the scatter and absorption data, or reflectance data, for the paint color, generating, based on the paint color data, full hiding color data representing the reflectance of the paint color at full hiding, generating, for a plurality of undercoat paints with different reflectance levels, color combination data representing the color of at least one coat of the paint color and one of the undercoat paints, respectively, and generating color difference data representing opacity, based on a difference between the full hiding color data and the color data combination.
    Type: Application
    Filed: February 27, 2006
    Publication date: August 20, 2009
    Applicant: ORICA AUSTRALIA PTY LTD
    Inventor: Peter Laurence McGinley
  • Patent number: 7557100
    Abstract: Described herein are antibacterial compounds, methods for making the compounds, pharmaceutical compositions containing the compounds and methods of treating bacterial infections utilizing the compounds and pharmaceutical composition.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: July 7, 2009
    Assignee: Pfizer Inc.
    Inventors: Timothy A. Johnson, Dennis J. McNamara, Debra A. Sherry, Peter Laurence Toogood
  • Patent number: 7456168
    Abstract: The present invention provides substituted 2-aminopyridines useful in treating cell proliferative disorders. The novel compounds of the present invention are potent inhibitors of cyclin-dependent kinases 4 (cdk4).
    Type: Grant
    Filed: April 11, 2007
    Date of Patent: November 25, 2008
    Assignee: Warner-Lambert Company
    Inventors: Mark Barvian, Richard John Booth, John Quin, III, Joseph Thomas Repine, Derek J. Sheehan, Peter Laurence Toogood, Scott Norman Vanderwel, Hairong Zhou
  • Publication number: 20080250590
    Abstract: A cleaning tool is disclosed for cleaning adjacent surfaces. In one embodiment, for instance, the cleaning tool may be used as a toilet bowl brush. The cleaning tool includes a handle comprised of a first handle member pivotally attached to a second handle member. Each handle member terminates in a clamping plate. The clamping plates move towards and away from each other as the handle members are likewise moved towards and away from each other. The handle can include a locking member that engages the first handle member with the second handle member in order to clamp or hold a cleaning pad in between the clamping plates. The clamping plates can include raised wave-like protrusions that further assist in gripping a cleaning pad.
    Type: Application
    Filed: December 29, 2006
    Publication date: October 16, 2008
    Inventors: Susan M. Trefethren, Craig M. Thoms, Brian James Ludka, Maggie VanderHeiden Berger, Christopher James Uecker, Carl Gerard Rippl, Peter Laurence
  • Patent number: 7345171
    Abstract: Disclosed are polymorphs of the isethionate salt of 6-acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one, which is a selective cyclin-dependent kinase 4 (CDK4) inhibitor useful for treating inflammation and cell proliferative diseases such as cancer and restenosis.
    Type: Grant
    Filed: July 6, 2004
    Date of Patent: March 18, 2008
    Assignee: Warner-Lambert Company LLC
    Inventors: Vladimar G. Beylin, Anthony Clyde Blackburn, David Thomas Erdman, Peter Laurence Toogood
  • Publication number: 20080044812
    Abstract: A method for the selective amplification of at least one target nucleic acid in a sample comprising a mixture of at least one target nucleic acid and at least one non-target nucleic acid. The method comprises: a nucleic acid denaturation step, wherein the denaturation step is carried out at a temperature at or above the melting temperature of the at least one target nucleic acid but below the melting temperature of the at least one non-target nucleic acid an amplification step using at least one amplification primer.
    Type: Application
    Filed: February 26, 2003
    Publication date: February 21, 2008
    Inventors: Peter Laurence Molloy, Keith Rand, Susan Joy Clark
  • Patent number: 7208490
    Abstract: The invention includes tetrahydroquinoline and related compounds of formula I, and pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens
    Type: Grant
    Filed: October 2, 2003
    Date of Patent: April 24, 2007
    Assignee: Pharmacia & Upjohn Company LLC
    Inventors: Michael Robert Barbachyn, Gordan L. Bundy, Paul Joseph Dobrowolski, Alexander Ross Hurd, Gary E. Martin, Dennis Joseph McNamara, John Raymond Palmer, Donna L. Romero, Arthur Glenn Romero, J. Craig Ruble, Debra Ann Sherry, Lisa Marie Thomasco, Peter Laurence Toogood
  • Patent number: 7208489
    Abstract: The present invention provides substituted 2-aminopyridines useful in treating cell proliferative disorders.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: April 24, 2007
    Assignee: Warner-Lambert Company
    Inventors: Mark Barvian, Richard John Booth, John Quin, III, Joseph Thomas Repine, Derek J. Sheehan, Peter Laurence Toogood, Scott Norman Vanderwel, Hairong Zhou
  • Patent number: 7169778
    Abstract: Disclosed are compounds of Formulae (Ia), (Ib), (Ic), (Id) wherein: W is NH, S, SO, or SO2; R2 is (un)substituted aryl, (un)substituted heteroaryl, or (un)substituted carbocycle or heterocycle; Q is hydrogen or lower alkyl; R4 and R6 are the same or different and represent hydrogen, halogen, lower alkyl, lower alkoxy, (un)substituted aryl, (un)substituted heteroaryl, (un)substituted arylalkyl or (un)substituted heteroarylalkyl; and R8 is hydrogen, lower alkyl or an (un)substituted carbocyclic group containing from 3–7 members, up to two of which members are optionally hetero atoms selected from oxygen and nitrogen; or R8 is (un)substituted aryl, (un)substituted heteroaryl, (un)substituted arylalkyl or (un)substituted heteroarylalkyl. These compounds are useful for treating cell proliferative disorders, such as cancer and restenosis. These compounds are potent inhibitors of cyclin-dependent kinases (cdks) and growth factor-mediated kinases.
    Type: Grant
    Filed: June 21, 2000
    Date of Patent: January 30, 2007
    Assignee: Warner-Lambert Company
    Inventors: William Alexander Denny, Gordon William Rewcastle, Ellen Dobrusin, James Bernard Kramer, Dennis Joseph McNamara, Howard Daniel Hollis Showalter, Peter Laurence Toogood
  • Patent number: 7074400
    Abstract: The invention provides regulatory constructs comprising intron 3 of the prostate specific membrane antigen gene (PSMA). An isolated nucleic acid molecule encoding the partial sequence of intron 3 of PSMA, a vector and a recombinant expression cassette are disclosed. The invention also provides a method of directing expression of a coding sequence in a prostate cell, a bladder cell, a breast cell and a vascular endothelial cell using the said constructs. This invention further provides a method of treatment of cancer using the said constructs.
    Type: Grant
    Filed: March 1, 2000
    Date of Patent: July 11, 2006
    Assignee: The Commonwealth of Australia
    Inventors: Peter Laurence Molloy, Fujiko Watt
  • Patent number: 7053070
    Abstract: Disclosed are compounds of the formula wherein R2, R5, R6, R7, and R8 are as defined herein. These compounds and their pharmaceutical compositions are useful for treating cell proliferative disorders, such as cancer and restenosis. These compounds are potent inhibitors of cdks and growth factor-mediated kinases.
    Type: Grant
    Filed: January 23, 2001
    Date of Patent: May 30, 2006
    Assignee: Warner-Lambert Company
    Inventors: Richard John Booth, Ellen Myra Dobrusin, Vara Prasad Venkata Nagendra Josyula, Dennis Joseph Mc Namara, Peter Laurence Toogood
  • Patent number: 6974879
    Abstract: A process for synthesizing L and D-5,5,5,5?,5?,5?-hexafluoroleucine and protected analogs is disclosed. These compounds have utility in the preparation of fluorous peptides and proteins, which display interesting and unusual properties including strong self-association and an affinity for lipid bilayers.
    Type: Grant
    Filed: August 3, 2004
    Date of Patent: December 13, 2005
    Assignee: Warner-Lambert Company
    Inventors: James T. Anderson, Edward Neil Marsh, Peter Laurence Toogood
  • Patent number: 6936612
    Abstract: The present invention provides substituted 2-aminopyridines useful in treating cell proliferative disorders.
    Type: Grant
    Filed: January 16, 2003
    Date of Patent: August 30, 2005
    Assignee: Warner-Lambert Company
    Inventors: Mark Barvian, Richard John Booth, John Quin, III, Joseph Thomas Repine, Derek J. Sheehan, Peter Laurence Toogood, Scott Norman Vanderwel, Hairong Zhou
  • Publication number: 20040236084
    Abstract: The present invention provides substituted 2-aminopyridines of formula I, wherein R1, A1, W, X, and Y are as defined in the specification, useful in treating cell proliferative disorders.
    Type: Application
    Filed: January 16, 2004
    Publication date: November 25, 2004
    Applicant: Pfizer Inc
    Inventors: Cathlin Marie Biwersi, Dennis Joseph McNamara, Joseph Thomas Repine, Peter Laurence Toogood, Scott Norman Vanderwel, Joseph Scott Warmus
  • Patent number: 6787664
    Abstract: A process for synthesizing L and D-5,5,5,5′,5′,5′-hexafluoroleucine and protected analogs is disclosed. These compounds have utility in the preparation of fluorous peptides and proteins, which display interesting and unusual properties including strong self-association and an affinity for lipid bilayers.
    Type: Grant
    Filed: September 16, 2003
    Date of Patent: September 7, 2004
    Assignees: Warner-Lambert Company LLC, The Regents of the University of Michigan
    Inventors: James T. Anderson, Edward Neil Marsh, Peter Laurence Toogood
  • Publication number: 20040162279
    Abstract: The invention includes tetrahydroquinoline and related compounds of formula I, and pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens.
    Type: Application
    Filed: October 2, 2003
    Publication date: August 19, 2004
    Inventors: Michael Robert Barbachyn, J. Craig Ruble, Arthur Glenn Romero, Lisa Marie Thomasco, Alexander Ross Hurd, John Raymond Palmer, Peter Laurence Toogood, Dennis Joseph McNamara, Debra Ann Sherry, Paul Joseph Dobrowolski
  • Publication number: 20040158065
    Abstract: Methods and materials for preparing irreversible inhibitors of tyrosine kinases of general Formula 1 are disclosed. Such inhibitors, which include N-[4-(3-chloro-4-floro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide, are useful for treating cancer, restenosis, atherosclerosis, endometriosis and psoriasis. The disclosed methods employ protecting schemes to minimize undesirable diacryloylamino-quinazoline side products.
    Type: Application
    Filed: February 4, 2004
    Publication date: August 12, 2004
    Inventors: Hubert Barth, Alexander James Bridges, Ronald J. Heemstra, Nicole Marcia Horne, Robert Craig Hughes, Thomas Elliott Jacks, Dennis Joseph McNamara, Simon Schneider, Klaus Steiner, Peter Laurence Toogood, Roy Thomas Winters
  • Publication number: 20040110982
    Abstract: A process for synthesizing L and D-5,5,5,5′,5′,5′-hexafluoroleucine and protected analogs is disclosed. These compounds have utility in the preparation of fluorous peptides and proteins, which display interesting and unusual properties including strong self-association and an affinity for lipid bilayers.
    Type: Application
    Filed: September 16, 2003
    Publication date: June 10, 2004
    Inventors: James T. Anderson, Edward Neil Marsh, Peter Laurence Toogood
  • Publication number: 20030149001
    Abstract: The present invention provides substituted 2-aminopyridines useful in treating cell proliferative disorders. The novel compounds of the present invention are potent inhibitors of cyclin-dependent kinases 4 (cdk4).
    Type: Application
    Filed: January 16, 2003
    Publication date: August 7, 2003
    Inventors: Mark Barvian, Richard John Booth, John Ouin, Joseph Thomas Repine, Derek J. Sheehan, Peter Laurence Toogood, Scott Norman Vanderwel, Hairong Zhou
  • Publication number: 20030130286
    Abstract: Disclosed are compounds of Formulae (Ia), (Ib), (Ic), (Id) wherein: W is NH, S, SO, or SO2; R2 is (un)substituted aryl, (un)substituted heteroaryl, or (un)substituted carbocycle or heterocycle; Q is hydrogen or lower alkyl; R4 and R6 are the same or different and represent hydrogen, halogen, lower alkyl, lower alkoxy, (un)substituted aryl, (un)substituted heteroaryl, (un)substituted arylalkyl or (un)substituted heteroarylalkyl; and R8 is hydrogen, lower alkyl or an (un)substituted carbocyclic group containing from 3-7 members, up to two of which members are optionally hetero atoms selected from oxygen and nitrogen; or R8 is (un)substituted aryl, (un)substituted heteroaryl, (un)substituted arylalkyl or (un)substituted heteroarylalkyl. These compounds are useful for treating cell proliferative disorders, such as cancer and restenosis. These compounds are potent inhibitors of cyclin-dependent kinases (cdks) and growth factor-mediated kinases.
    Type: Application
    Filed: March 6, 2002
    Publication date: July 10, 2003
    Inventors: William Alexander Denny, Gordon William Rewcastle, Ellen Dobrusin, James Bernard Kramer, Dennis Joseph McNamara, Howard Daniel Hollis Showalter, Peter Laurence Toogood