Abstract: A method executed by a computing entity includes obtaining, in accordance with a securely passing process, control over a secure first token representing a first pending transaction associated with a transaction item. The method further includes obtaining a selection of a first subset of instant assets of a set of candidate instant assets that may be utilized to subsequently provide conversion of credits of a set of selected public benefit assets to complete the first pending transaction. The method further includes generating an updated secure first token in accordance with the securely passing process to represent the selection of the first subset of instant assets of the set of candidate instant assets to subsequently provide the conversion of the set of selected public benefit assets to complete the first pending transaction.

Abstract: In one aspect, an implant for replacing subject tissue includes a nonbiologic portion and a biologic portion grown on the nonbiologic portion. The biologic portion may be grown on the nonbiologic portion before being implanted in the subject. The nonbiologic portion may comprise a porous metal substrate (e.g., scaffolding). The nonbiologic portion may be formed by 3D printing (i.e., additive manufacturing). The nonbiologic portion may be patient-specific. A robot may be used to shape the implant before implantation and/or to shape bone being replaced/resurfaced.

Abstract: The present disclosure provides systems, methods, and compositions for prime-editing modification of c.828 splice site mutations in the peripherin-2 gene. Particularly the present disclosure provides systems, methods, and compositions for correcting one or more disease-causing splice site mutations selected from: c.828+3A>T, c.828+1G>A, c.828+2T>C, c.828+1G>T, and combinations thereof.

Abstract: An endoscopic system includes a shaft comprising a proximal end portion and a distal end portion; a sensor system; a floating ground element electrically coupled to the sensor system; a power regulator electrically coupled to a power transmission line and to the floating ground element, the power regulator configured to convert ground-referenced power received from an earth ground referenced power source into floating ground element referenced power and to output the floating ground element referenced power through the power transmission line; and a circuit enclosure at least partially enclosing a transceiver circuit and the power regulator, the circuit enclosure being electrically coupled with the floating ground element.

Abstract: A method for estimating a remaining range of a vehicle battery charge includes identifying at least one route characteristic of a portion of a selected route, determining a vehicle energy consumption profile for a vehicle, and determining a current state of charge of a vehicle battery of the vehicle. The method also includes determining, for the selected route, a route energy consumption profile and calculating an estimated remaining charge for the vehicle battery at an end of the selected route based on the state of charge of the vehicle battery and the route energy consumption profile. The method also includes, in response to a determination that the estimated remaining charge is less than a lower limit of the vehicle battery charge range, determining a target vehicle speed profile based on the at least one route characteristic, the vehicle energy consumption profile, and the state of charge of the vehicle battery.

Abstract: The disclosure provides a composition for inhibiting thrombosis. The composition includes 5 to 25% by weight of Fish Oil, 15 to 55% by weight of Willow Bark Extract, and 0.2 to 5% by weight of Vitamin E.

Abstract: According to some embodiments, an automated scoring analysis computer may access information in a historical data store, including sets of attribute values and prior results for a plurality of prior associations, to create a scoring model. An indication of a selected potential association from a potential association data store may be received, including a set of attribute values. The scoring analysis computer may then calculate a risk score for the selected potential association based on the scoring model. A front-end application computer server may automatically select a workflow path from a plurality of potential workflow paths.

Abstract: Bed heating systems that include a DC-heated bedding assembly and/or a DC-powered control system. The DC-heated bedding assembly includes a substrate, which supports a heating element configured to receive electrical power from a DC power supply and to generate a heat output to heat the substrate. The heating element may extend sinusoidally along the substrate. The heating element may be configured to generate different heat outputs in two or more zones of the substrate. The DC-powered control systems are configured to selectively regulate electrical power that is supplied to the heating element of the DC-heated bedding assembly. The DC-powered control systems are configured to monitor detected voltage(s) at one or more voltage taps positioned along the length of the heating element. Responsive to detecting a deviation between the detected voltage and an expected voltage, the DC-powered control systems may reduce and/or cease the supply of power to the heating element.

Abstract: A method for power amplification uses circuitry including a main amplifier and an auxiliary amplifier that are constructed and operate such that an input is applied to the main and auxiliary amplifiers via an input network. At low power levels, the auxiliary amplifier is off and the main amplifier sees a large impedance. At maximum power level, both the auxiliary and main amplifiers operate at full power and there is a constant phase shift between them. While transitioning from low to maximum power, systematic AM-AM and AM-PM variations generated due to the phase shift provided by the input network, bias differences between the main and auxiliary amplifiers, and nature of the output combiner to compensate device related distortions.

Abstract: A method for controller vehicle propulsion. The method includes identifying at least one route characteristic of a portion of a most probable path, determining a vehicle energy consumption profile for a vehicle based on at least historical data indicating energy consumption of the vehicle for at least a portion of a route previously traversed by the vehicle having at least one route characteristic corresponding to the at least one route characteristic of the portion of the most probable path, and determining, for the most probable path, a route energy consumption profile based on the at least one route characteristic of the portion of the most probable path and the vehicle energy consumption profile. The method also includes determining a target vehicle speed profile based on the at least one route characteristic and the vehicle energy consumption profile and selectively controlling vehicle propulsion based on the target vehicle speed profile.

Abstract: Provided herein are inhibitors of SLC26A3, which is an anion (Cl?, HCO3?, oxalate) exchanger expressed in intestinal epithelial cells. SLC26A3 inhibitors have potential utility for treatment of constipation including chronic idiopathic constipation (CIC), opioid-induced constipation (OIC), constipation-predominant irritable bowel syndrome (IBS-C), cystic fibrosis-associated constipation, meconium ileus, distal intestinal obstruction syndrome, calcium oxalate kidney stone disease, enteric hyperoxaluria and primary hyperoxalurias.

Abstract: A collet member for a colleting fixture includes a monolithic collet body having a clamping block engaging outer wall and a workpiece engaging inner wall extending circumferentially between first and second end walls, with each of the outer wall, the inner wall, and the first and second end walls extending axially between first and second radial walls to enclose at least one internal cavity.

Abstract: A mechanical wallet or cardholder can be opened using one hand by sliding a top or second plate along rails parallel to a bottom or first plate. A card arm forces cards in the cardholder (i.e., located between the first and second plates) out a second end of the cardholder in a fanned or stepped fashion. A magnet in the card arm and in a first end of the frame (opposite the second end of the cardholder and frame) cooperate to return and retain the card arm and first plate in the closed position. A card lock at the second end of the frame retains cards in the cardholder when the cardholder is in the closed position and allows the cards to be pushed from the second end of the cardholder by the card arm when the second plate is moved to the open position.

Abstract: A disinfecting system includes a housing. An ultraviolet light (UV) source is secured to the housing and configured to emit UV light for disinfection of a target. A processor is secured to the housing in communication with the UV light source. The processor is configured to activate the UV light source for a selected amount of time suitable for disinfection of the target.

Abstract: A manufacturing method is provided during which an aperture is machined into workpiece using a laser beam. An image of an interaction between the laser beam and the workpiece is captured during the machining of the aperture using a camera with an electronic shutter. A parameter associated with the aperture is determined based on information from the image.

Abstract: Devices and systems useful in concurrently receiving and transmitting Wi-Fi signals and Bluetooth signals in the same frequency band are provided. By way of example, an electronic device includes a transceiver configured to transmit data and to receive data over channels of a first wireless network and a second wireless network concurrently. The transceiver includes a plurality of filters configured to allow the transceiver to transmit the data and to receive the data in the same frequency band by reducing interference between signals of the first wireless network and the second wireless network.

Abstract: The invention primarily relates to fastening and stabilizing tissues, implants, and/or bondable materials, such as the fastening of a tissue and/or implant to a bondable material, the fastening of an implant to tissue, and/or the fastening of an implant to another implant. This may involve using an energy source to bond and/or mechanically to stabilize a tissue, an implant, a bondable material, and/or other biocompatible material. The invention may also relate to the use of an energy source to remove and/or install an implant and/or bondable material or to facilitate solidification and/or polymerization of bondable material.

Abstract: A method and apparatus are provided for sorting or retrieving items to/from a plurality of destinations areas. The items are loaded onto one of a plurality of independently controlled delivery vehicles. The delivery vehicles follow a track that guides the delivery vehicles to/from the destination areas, which are positioned along the track. Once at the appropriate destination area, an item is transferred between the delivery vehicle and the destination area.

Abstract: A method includes a computing entity issuing to an asset authenticity computing entity a request to select and authenticate a digital record that represents an available contingent asset based on a digital record representing a hypothetical contingent asset to produce a selected contingent asset. The method further includes determining that authenticity information associated with the selected contingent asset indicates that the selected contingent asset matches the hypothetical contingent asset. The method further includes, when approved, generating a smart contract to indicate availability of the selected contingent asset and obtaining a copy of an object distributed ledger. The method further includes causing inclusion of a next block on the object distributed ledger that includes the smart contract to represent the selected contingent asset.

Abstract: In some implementations, a device may obtain an input indicating information associated with one or more attributes of an entity. The device may analyze the input to identify one or more words or phrases from the input. The device may detect one or more domain specific language (DSL) keywords, from the one or more words or phrases, indicative of one or more brand parameters associated with the entity. The device may provide, to a machine learning model, an indication of the entity and the one or more words or phrases. The device may obtain, via an output of the machine learning model and based on providing the indication of the entity and the one or more words or phrases, an indication of updates to be made for the one or more brand parameters. The device may perform an action based on the output of the machine learning model.