Abstract: A composition of psilocin that is stable including at least one agent or chemical modification that provides enhanced stability. A method making stable psilocin, by providing a formulation of psilocin including at least one agent or chemical modification that provides enhanced stability. A method of treatment of a disease or condition, by administering a composition of psilocin that is stable to an individual and treating the disease or condition.

Abstract: A solid oral immediate release formulation of LSD, including LSD contained within a dosage form of a capsule, tablet, or orally disintegrating tablet. A method of making a solid oral immediate release formulation of LSD as a free base or in a salt form by granulation, including moisture-activated dry granulation or dry blending. A method of treating an individual, by administering a solid oral immediate release formulation of LSD and treating the individual.

Abstract: A solid oral immediate release formulation of LSD, wherein the composition is produced by lyophilization of a feedstock in a pre-formed mold to form an orally disintegrating tablet. A method of making a solid oral immediate release formulation of LSD by lyophilizing a flash frozen stock solution of LSD and excipients, including a non-gelling matrix former, filler, and binder in a pre-formed mold, and forming an orally disintegrating tablet. A method of treating an individual by administering a solid oral immediate release formulation of LSD, wherein the composition is produced by lyophilization of a feedstock in a pre-formed mold to form an orally disintegrating tablet and treating the individual.

Abstract: A solid oral immediate release formulation of LSD, wherein the composition is produced by lyophilization of a feedstock in a pre-formed mold to form an orally disintegrating tablet. A method of making a solid oral immediate release formulation of LSD by lyophilizing a flash frozen stock solution of LSD and excipients, including a non-gelling matrix former, filler, and binder in a pre-formed mold, and forming an orally disintegrating tablet. A method of treating an individual by administering a solid oral immediate release formulation of LSD, wherein the composition is produced by lyophilization of a feedstock in a pre-formed mold to form an orally disintegrating tablet and treating the individual.

Abstract: A solid oral immediate release formulation of LSD, including LSD contained within a dosage form of a capsule, tablet, or orally disintegrating tablet. A method of making a solid oral immediate release formulation of LSD as a free base or in a salt form by granulation, including moisture-activated dry granulation or dry blending. A method of treating an individual, by administering a solid oral immediate release formulation of LSD and treating the individual.

Abstract: A solid oral immediate release formulation of LSD, wherein the composition is produced by lyophilization of a feedstock in a pre-formed mold to form an orally disintegrating tablet. A method of making a solid oral immediate release formulation of LSD by lyophilizing a flash frozen stock solution of LSD and excipients, including a non-gelling matrix former, filler, and binder in a pre-formed mold, and forming an orally disintegrating tablet. A method of treating an individual by administering a solid oral immediate release formulation of LSD, wherein the composition is produced by lyophilization of a feedstock in a pre-formed mold to form an orally disintegrating tablet and treating the individual.

Abstract: A solid oral immediate release formulation of LSD, including LSD contained within a dosage form of a capsule, tablet, or orally disintegrating tablet. A method of making a solid oral immediate release formulation of LSD as a free base or in a salt form by granulation, including moisture-activated dry granulation or dry blending. A method of treating an individual, by administering a solid oral immediate release formulation of LSD and treating the individual.

Abstract: A composition of psilocin that is stable including at least one agent or chemical modification that provides enhanced stability. A method making stable psilocin, by providing a formulation of psilocin including at least one agent or chemical modification that provides enhanced stability. A method of treatment of a disease or condition, by administering a composition of psilocin that is stable to an individual and treating the disease or condition.

Abstract: A composition of psilocin that is stable including at least one agent or chemical modification that provides enhanced stability. A method making stable psilocin, by providing a formulation of psilocin including at least one agent or chemical modification that provides enhanced stability. A method of treatment of a disease or condition, by administering a composition of psilocin that is stable to an individual, and treating the disease or condition.

Abstract: Microfluidic structures featuring substantially circular channels may be fabricated by embossing polymer sheets.

Abstract: The systems and methods described herein relate to a high-throughput flow apparatus. The apparatus is used with an array of wells, and is configured to impart a predetermined shear stress on cells cultured within each of the wells of the array of wells. The apparatus includes a plurality of mechanical tips. The plurality of mechanical tips each includes a head with a hemispheroid shape. The apparatus also includes a motor associated with at least one of plurality of mechanical tips. The motor is configured to drive the plurality of mechanical tips to impart the shear stress pattern in each of the wells.

Abstract: Microfluidic structures featuring substantially circular channels may be fabricated by embossing polymer sheets.

Abstract: Microfluidic structures featuring substantially circular channels may be fabricated by embossing polymer sheets.

Abstract: The systems and methods described herein relate to a high-throughput flow apparatus. The apparatus is used with an array of wells, and is configured to impart a predetermined shear stress on cells cultured within each of the wells of the array of wells. The apparatus includes a plurality of mechanical tips. The plurality of mechanical tips each includes a head with a hemispheroid shape. The apparatus also includes a motor associated with at least one of plurality of mechanical tips. The motor is configured to drive the plurality of mechanical tips to impart the shear stress pattern in each of the wells.

Abstract: A high-throughput flow system includes an array of wells and a separate mechanical tip positioned within each well. Each mechanical tip is separately actuated to impart a shear stress pattern. A separate sleeve may be associated with each tip for maintaining a predetermined distance between the tip and a floor of the tip's corresponding well, with each tip being rotatable within its corresponding sleeve. Alternatively, a separate post may be associated with each tip for maintaining a predetermined distance between the tip and a floor of the tip's corresponding well, with each tip being rotatable about its corresponding post.

Abstract: A phase locked loop (PLL) lock detector may be configured to observe the phase error signal from a phase comparator of a PLL circuit. The PLL lock detector may accumulate a sum of phase errors and compare the sum of phase errors to determine whether the PLL circuit is locked in phase with the reference signal. Various modifications to the phase error signal and sum of phase errors may be used to improve the efficiency of the PLL lock detector. Configurable settings for the accumulator and a comparator may be used to adjust the operation of the PLL lock detector.

Abstract: A mechanism can be implemented in a communication unit of a network device to utilize periods of silence encountered in voice communication to conserve power at the network device. In some embodiments, it can be determined that one or more packets of a received RF signal comprise audio data. The communication unit of the network device can determine whether the audio data associated with the one or more packets comprises voice information. The network device can switch to a power save mode based, at least in part, on determining that the audio data associated with the one or more packets does not comprise voice information.

Abstract: A tri-state control mechanism can be implemented for a line driver of a transmitter unit to switch the output impedance of the transmitter unit between a low impedance state in the transmit mode and a high impedance state in the receive mode while minimizing turn-off glitch. It may be determined whether a communication device comprising the transmitter unit is configured in a transmit operating mode or a receive operating mode. If the communication device is configured in the receive operating mode, a first bias voltage can be generated to bias output transistors of the line driver circuit in a sub-threshold state. If the communication device is configured in the transmit operating mode, a second bias voltage can be generated to bias output transistors of the line driver circuit in a saturation state.

Abstract: A hybrid SAR ADC can be implemented to reduce the number of operations that are executed to convert an analog input signal into its digital representation. Pipeline processing operations can be executed on the analog input signal to generate pipeline bits (MSBs of the digital representation) and an analog residue signal. The analog residue signal can be compared against a plurality of thresholds to generate comparator bits that are indicative of a range associated with a subset of the predetermined thresholds that correspond to the analog residue signal. Successive approximation analog-to-digital conversion operations can be executed on the analog residue signal to generate successive approximation bits. The digital representation can be determined based, at least in part, on the pipeline bits, the comparator bits, and the successive approximation bits.

Abstract: A hybrid SAR ADC can be implemented to reduce the number of operations that are executed to convert an analog input signal into its digital representation. Pipeline processing operations can be executed on the analog input signal to generate pipeline bits (MSBs of the digital representation) and an analog residue signal. The analog residue signal can be compared against a plurality of thresholds to generate comparator bits that are indicative of a range associated with a subset of the predetermined thresholds that correspond to the analog residue signal. Successive approximation analog-to-digital conversion operations can be executed on the analog residue signal to generate successive approximation bits. The digital representation can be determined based, at least in part, on the pipeline bits, the comparator bits, and the successive approximation bits.