Abstract: A system for generating a topology of components based on a set of components provided by a user. The system identifies, for each particular component of the first set of components, one or more characteristics. The characteristics may include at least one of: a rule associated with the particular component, a requirement associated with the particular component, a data input type corresponding to the particular component, and data output type corresponding to the particular component. Based on the characteristics, the system determines that an additional component not included in the first set of components is required for connecting the first set of components. The system selects the additional component and determines a topology of components that includes the first set of components and the additional component. The system also determines a dataflow between components in the topology of components.

Abstract: A method for controlling vehicle propulsion may include identifying at least one route characteristic of a portion of a route being traversed by a vehicle and determining a profile for a target vehicle speed based on the at least one route characteristic and a vehicle energy consumption profile. The method may also include, in response to detecting a lead vehicle, determining a vehicle speed of the lead vehicle and determining whether to avoid triggering initiation of the vehicle follow mode by the vehicle propulsion controller based on (i) a distance between the vehicle and a triggering threshold and (ii) the vehicle speed of the vehicle. The method may also include, in response to not triggering vehicle follow mode, determining, based on the vehicle speed of the lead vehicle and the profile for the target vehicle speed, a traveling distance between the vehicle and a trigger threshold.

Abstract: A flexible, flame-retardant composite material includes a fabric layer; and at least one impregnated or coated Polyvinyl Butyral (PVB) coating layer, which is integral with said fabric layer. The PVB coating layer contains 20 to 60% by weight of PVB, at least one plasticizer in an amount of 5 to 40% by weight of the coating layer, and at least one flame retardant in a total amount of 5 to 75% by weight with respect to the coating layer. A manufacturing method thereof is also described, and includes an impregnation or coating of a water-based dispersion of PVB onto the fabric layer, and a further curing.

Abstract: An apparatus includes a CPU core and a L1 cache subsystem including a L1 main cache, a L1 victim cache, and a L1 controller. The apparatus includes a L2 cache subsystem coupled to the L1 cache subsystem by a transaction bus and a tag update bus. The L2 cache subsystem includes a L2 main cache, a shadow L1 main cache, a shadow L1 victim cache, and a L2 controller. The L2 controller receives a message from the L1 controller over the tag update bus, including a valid signal, an address, and a coherence state. In response to the valid signal being asserted, the L2 controller identifies an entry in the shadow L1 main cache or the shadow L1 victim cache having an address corresponding to the address of the message and updates a coherence state of the identified entry to be the coherence state of the message.

Abstract: The present disclosure provides controllers for power distribution network circuit interrupting devices and provides electronic control circuits for inclusion in such controllers. The electronic control circuit has a boost circuit, a capacitor storage unit and a pulse width modulator control circuit. The boost circuit boosts an input voltage to a value to supply sufficient energy to a protective relay solenoid to energize the solenoid. The capacitor storage unit stores the boosted voltage from the boost circuit. The pulse width modulator control circuit is responsive to a control and enable circuit to selectively enable energy from the capacitor to energize the one or more protective relays in power distribution system circuit interrupting device.

Abstract: This invention relates to binding molecules that bind specifically Vascular Endothelial Growth Factor (VEGF) and Tropomyosin receptor kinase B (TrkB) and their use in medicine, pharmaceutical compositions comprising the same, and methods of using the same as agents for treatment and/or prevention of diseases of the eye.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for generating synthetic training data representing network disruptions. One of the methods includes obtaining data representing one or more first travel time distributions between at the at least two entities in the supply chain network. Synthetic network disruption data is generated including sampling from one or more second travel time distributions corresponding respectively to one or more simulated network disruptions. A second dataset having the synthetic network disruption data is generated, and a network policy agent is trained using the second dataset.

Abstract: An orchestration cluster node system may include a plurality of local orchestration cluster nodes. Each local cluster node may include a service request executor, coordination function, and a resource manager. Each local cluster node may operate in a geography and the coordination functions of local cluster codes may communicate to coordinate execution of services across geographies.

Abstract: The present disclosure provides exemplary embodiments of voltage harvesting devices used in power distribution systems, and provides power distribution system architectures utilizing the voltage harvesting devices. Generally, the voltage harvesting devices transform distribution line AC voltages to produce a low wattage output for distribution system communication and control type devices. The voltage harvesting device can operate whether irrespective of the presence of load current.

Abstract: The present disclosure provides systems and methods for animal health monitoring. Load data can be obtained from an animal monitoring device including three or more load sensors associated with a platform carrying contained litter thereabove, wherein individual load sensors of the three or more load sensors are separated from one another and receive pressure input from the platform independent of one another, wherein the three or more load sensors individually sample loads at from 2.5 Hz to 110 Hz. An animal behavior property associated with the animal can be recognized if it is determined based on load data that the interaction with the contained litter was due to the animal interaction with the contained litter. The animal behavior property can be classified into an animal classified event using a machine learning classifier.

Abstract: Cargo assemblages including a pallet, a load of packages arranged in one or more layers, and a support layer, in which the support layer is sized and positioned within the cargo assemblage to support and/or stabilize the cargo, thereby providing improved pallet efficiency, improved shipping efficiency, and/or improved stability.

Abstract: The present invention relates to treatment of subgroups of cancer patients, methods for identifying treatment and dosage regimens, as well as methods for identifying these subgroups of cancer patients.

Abstract: This disclosure concerns compositions and methods for novel RNA inhibition molecules (e.g., small/short hairpin RNA (shRNA) molecules), polynucleotides encoding such molecules, use of such novel RNA inhibition molecules to inhibit a target gene by suppressing the expression of the mRNA of the target gene, and for application such as the of control insect pests, and transgenic plants that produce, and are protected, by these novel RNA inhibition molecules are described.

Abstract: Herein is reported a recombinant fusion polypeptide comprising an antibody heavy chain variable domain, a multimerization domain and an antibody light chain variable domain, wherein the antibody heavy chain variable domain is fused (either directly or via a first (peptidic) linker) to one terminus of the multimerization domain, the antibody light chain variable domain is fused (either directly or via a second (peptidic) linker) to the respective other terminus of the multimerization domain, and the antibody heavy chain variable domain or the antibody light chain variable domain has a (intra-peptidic) disulphide bond to the multimerization domain.

Abstract: A computer-implemented method includes obtaining, via a processor, clinical images including vessels and generating, via the processor, straightened-out images for each coronary tree path within respective clinical images, The method also includes extracting, via the processor, segmented 3D image patches, determining, via the processor, overlapping binary mask volumes for each segment, and predicting, via the processor, pressure drops across the segmented image patches using a trained deep neural network.

Abstract: The present invention relates to a protective covering for grapevines to mitigate smoke taint by filtering particles that may affect the grapes. The protective covering: comprises a microporous activated carbon material that is capable of being arranged by a user to cover at least a portion of the grapevine; and an attachment means for securing the activated carbon material to, or about, at least the portion of the grapevine.

Abstract: An apparatus includes a CPU core and a L1 cache subsystem including a L1 main cache, a L1 victim cache, and a L1 controller. The apparatus includes a L2 cache subsystem coupled to the L1 cache subsystem by a transaction bus and a tag update bus. The L2 cache subsystem includes a L2 main cache, a shadow L1 main cache, a shadow L1 victim cache, and a L2 controller. The L2 controller receives a message from the L1 controller over the tag update bus, including a valid signal, an address, and a coherence state. In response to the valid signal being asserted, the L2 controller identifies an entry in the shadow L1 main cache or the shadow L1 victim cache having an address corresponding to the address of the message and updates a coherence state of the identified entry to be the coherence state of the message.

Abstract: Disclosed are genetic control circuits, cells, and methods that use a repressor polypeptide to reduce the transcription rate of an exogenous therapeutic polypeptide encoding gene in response to a change in condition.

Abstract: Techniques are described for a social networking system to provide collective accounts that allow for multiple holders, editors, and/or managers. In some cases, the social networking system may be configured to distribute content associated with the collective accounts based on metrics and relationships associated with accounts of the contributors to the collective account as well as the collective account itself.