Abstract: The invention relates to a method of loading a medical device, in particular to a dialysis device, and preferably a peritoneal dialysis device, which comprises a device control and a user interface, wherein at least one fluid-filled container is connected to a corresponding interface of the device, wherein at least one property of the container is checked by the device before or during its connection and the measured value is compared with least one desired value stored in the device control.

Abstract: An air jet spinning machine, air jet spinning machine for producing a thread from a fed sliver, and method for detecting a thread strength, which falls below a target value, of a thread produced at a spinning unit of an airjet spinning machine are provided. A thread manipulation unit is arranged in the region between the airjet spinning machine and the spooling device, which thread manipulation unit acts mechanically on the thread and exerts an adjustable thread tension influencing force, in particular an adjustable braking force, compression force and/or clamping force, onto the thread in order to variably increase thread tension. In the method, an adjustable thread tension influencing force is exerted onto the thread, and a thread breakage and/or thread breakage rate are/is detected and compared with a specified target rate, and thread breakage and/or deviations of thread breakage rate beyond a predetermined limit value are displayed and/or evaluated.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R23 are as described herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein R2, R3, R4, R5, R6, R7, R3, R8, R10, R11 and R23 are as described herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, A, X and R11 are as described herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein R2, R3, R4, R5, R6, R7, R8, X, A and R11 are as described herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R3, R8, R9, R10 and R11 are as described herein, compositions including the compounds and methods of using the compounds.

Abstract: A clamping device for clamping a workpiece or a tool or, more specifically, a tool holding fixture in a machine part of a machine tool includes a tension rod slidably mounted within the machine part; a clamping set movable by the tension rod between clamped and released positions; a tension spring dedicated to the tension rod so as to generate the pull-in force of the clamping set; and a release mechanism, by which the clamping set can be moved against the force of the tension spring into the released position by the tension rod. To make possible effective clamping at optimum force, the tension spring is clamped between first and second rod parts of the tension rod. The second rod part can move relative to the first rod part, and, as the clamping set moves into the released position, is compressed on both ends by the release mechanism by moving the two rod parts in opposite directions.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as described herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein R2, R3, R4, R5, R6, R7, R8, X, A and R11 are as described herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, A, X and R11 are as described herein, compositions including the compounds and methods of using the compounds.

Abstract: The present invention is directed compositions for targeted delivery of RNA interference (RNAi) polynucleotides to hepatocytes in vivo. Targeted RNAi polynucleotides are administered together with co-targeted delivery polymers. Delivery polymers provide membrane penetration function for movement of the RNAi polynucleotides from outside the cell to inside the cell. Reversible modification provides physiological responsiveness to the delivery polymers.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R3, R8, R9, R10 and R11 are as described herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R3, R8, R9, R10, R11 and R23 are as described herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds having the general formula (I) wherein R2, R3, R4, R5, R6, R7, R3, R8, R10, R11 and R23 are as described herein, compositions including the compounds and methods of using the compounds.

Abstract: For an image processing concept, a database including data derived from a plurality of frames of a video is provided in a device. A live video feed is obtained from a camera of the device. Information is extracted from an image of the video feed. A search is performed in the database using the extracted information to retrieve a list of potential frames out of the plurality of frames. An initial pose of the selected image is estimated with respect to one frame of the list as a function of the extracted information and the data derived from the one frame. Respective subsequent poses for subsequent images from the live video feed are iteratively estimated, wherein the associated subsequent pose is estimated based on said subsequent image and a respective previously estimated pose. The video feed is augmented on the device with virtual information based on the estimated initial pose and the subsequent poses.

Abstract: A clamping device for clamping a workpiece or a tool or, more specifically, a tool holding fixture in a machine part of a machine tool includes a tension rod slidably mounted within the machine part; a clamping set movable by the tension rod between clamped and released positions; a tension spring dedicated to the tension rod so as to generate the pull-in force of the clamping set; and a release mechanism, by which the clamping set can be moved against the force of the tension spring into the released position by the tension rod. To make possible effective clamping at optimum force, the tension spring is clamped between first and second rod parts of the tension rod. The second rod part can move relative to the first rod part, and, as the clamping set moves into the released position, is compressed on both ends by the release mechanism by moving the two rod parts in opposite directions.

Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6 and R7 are as described herein, compositions including the compounds and methods of using the compounds.

Abstract: The invention provides novel compounds and conjugates of these compounds useful for the delivery of biologically active substances. Further novel design criteria for chemically stabilized siRNA particular useful when covalently attached to a delivery polymer to achieve in vivo mRNA knock down are disclosed therein.

Abstract: A clamping device for clamping a workpiece or a tool or a tool holder to a machine component of a machine tool, having an axially movable tension rod, a clamping assembly which can be moved by the tension rod between a clamped position and a released position, a spring assembly dedicated to the tension rod with a plurality of series-connected spring units for generating the clamping and draw-in force of the clamping assembly, and a releasing unit by which the clamping assembly can be moved by the tension rod against the force of the spring assembly into the released position. To ensure the most uniform load possible, the axial spring deflection of the spring units is limited by a stop when the spring assembly is compressed.