Patents by Inventor Peter Mohr

Peter Mohr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11014963
    Abstract: The invention provides novel compounds having the general formula (I) wherein R2, R3, R4, R5, R6, R7, R3, R8, R10, R11 and R23 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: May 25, 2021
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Benoit Hornsperger, Roberto Iacone, Hans P. Maerki, Peter Mohr, Michael Reutlinger
  • Patent number: 11001555
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, A, X and R11 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: May 11, 2021
    Assignee: Hoffman-La Roche Inc.
    Inventors: Benoit Hornsperger, Hans P. Maerki, Peter Mohr, Michael Reutlinger, Markus Rudolph
  • Patent number: 10870623
    Abstract: The invention provides novel compounds having the general formula (I) wherein R2, R3, R4, R5, R6, R7, R8, X, A and R11 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: December 22, 2020
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Benoit Hornsperger, Hans Peter Maerki, Peter Mohr, Michael Reutlinger, Markus Rudolph
  • Patent number: 10865182
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R3, R8, R9, R10 and R11 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: December 15, 2020
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Hans P. Maerki, Benoit Hornsperger, Peter Mohr, Michael Reutlinger, Markus Rudolph
  • Patent number: 10646929
    Abstract: A clamping device for clamping a workpiece or a tool or, more specifically, a tool holding fixture in a machine part of a machine tool includes a tension rod slidably mounted within the machine part; a clamping set movable by the tension rod between clamped and released positions; a tension spring dedicated to the tension rod so as to generate the pull-in force of the clamping set; and a release mechanism, by which the clamping set can be moved against the force of the tension spring into the released position by the tension rod. To make possible effective clamping at optimum force, the tension spring is clamped between first and second rod parts of the tension rod. The second rod part can move relative to the first rod part, and, as the clamping set moves into the released position, is compressed on both ends by the release mechanism by moving the two rod parts in opposite directions.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: May 12, 2020
    Assignee: Ott-Jakob Spanntechnik GmbH
    Inventors: Josef Greif, Peter Mohr, Conrad Rösch, Bartholomäus Reisacher
  • Patent number: 10428108
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: October 1, 2019
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Benoit Hornsperger, Roberto Iacone, Eric A. Kitas, Hans P. Maerki, Michael Reutlinger, Peter Mohr
  • Publication number: 20190185427
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, A, X and R11 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: February 22, 2019
    Publication date: June 20, 2019
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Benoit Hornsperger, Hans P. Maerki, Peter Mohr, Michael Reutlinger, Markus Rudolph
  • Publication number: 20190185426
    Abstract: The invention provides novel compounds having the general formula (I) wherein R2, R3, R4, R5, R6, R7, R8, X, A and R11 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: February 22, 2019
    Publication date: June 20, 2019
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Benoit HORNSPERGER, Hans Peter MAERKI, Peter MOHR, Michael REUTLINGER, Markus RUDOLPH
  • Patent number: 10316316
    Abstract: The present invention is directed compositions for targeted delivery of RNA interference (RNAi) polynucleotides to hepatocytes in vivo. Targeted RNAi polynucleotides are administered together with co-targeted delivery polymers. Delivery polymers provide membrane penetration function for movement of the RNAi polynucleotides from outside the cell to inside the cell. Reversible modification provides physiological responsiveness to the delivery polymers.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: June 11, 2019
    Assignee: Arrowhead Pharmaceuticals, Inc.
    Inventors: David L Lewis, David B Rozema, Darren H Wakefield, Torsten Hoffman, Erik Kitas, Peter Mohr, Philipp Hadwiger, Wilma Thuer, Linda Valis
  • Publication number: 20190152895
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R3, R8, R9, R10 and R11 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: January 17, 2019
    Publication date: May 23, 2019
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Hans P. MAERKI, Benoit HORNSPERGER, Peter MOHR, Michael REUTLINGER, Markus RUDOLPH
  • Publication number: 20180371015
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R3, R8, R9, R10, R11 and R23 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: September 4, 2018
    Publication date: December 27, 2018
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Hans P. Maerki, Benoit Hornsperger, Peter Mohr, Michael Reutlinger, Roberto Iacone
  • Publication number: 20180371016
    Abstract: The invention provides novel compounds having the general formula (I) wherein R2, R3, R4, R5, R6, R7, R3, R8, R10, R11 and R23 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: September 4, 2018
    Publication date: December 27, 2018
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Benoit Hornsperger, Roberto Iacone, Hans P. Maerki, Peter Mohr, Michael Reutlinger
  • Patent number: 10163224
    Abstract: For an image processing concept, a database including data derived from a plurality of frames of a video is provided in a device. A live video feed is obtained from a camera of the device. Information is extracted from an image of the video feed. A search is performed in the database using the extracted information to retrieve a list of potential frames out of the plurality of frames. An initial pose of the selected image is estimated with respect to one frame of the list as a function of the extracted information and the data derived from the one frame. Respective subsequent poses for subsequent images from the live video feed are iteratively estimated, wherein the associated subsequent pose is estimated based on said subsequent image and a respective previously estimated pose. The video feed is augmented on the device with virtual information based on the estimated initial pose and the subsequent poses.
    Type: Grant
    Filed: February 9, 2017
    Date of Patent: December 25, 2018
    Assignee: AR4 GMBH
    Inventors: Clemens Arth, Philipp Fleck, Denis Kalkofen, Peter Mohr, Dieter Schmalstieg
  • Publication number: 20180290215
    Abstract: A clamping device for clamping a workpiece or a tool or, more specifically, a tool holding fixture in a machine part of a machine tool includes a tension rod slidably mounted within the machine part; a clamping set movable by the tension rod between clamped and released positions; a tension spring dedicated to the tension rod so as to generate the pull-in force of the clamping set; and a release mechanism, by which the clamping set can be moved against the force of the tension spring into the released position by the tension rod. To make possible effective clamping at optimum force, the tension spring is clamped between first and second rod parts of the tension rod. The second rod part can move relative to the first rod part, and, as the clamping set moves into the released position, is compressed on both ends by the release mechanism by moving the two rod parts in opposite directions.
    Type: Application
    Filed: March 28, 2018
    Publication date: October 11, 2018
    Applicant: Ott-Jakob Spanntechnik GmbH
    Inventors: Josef GREIF, Peter MOHR, Conrad RÖSCH, Bartholomäus REISACHER
  • Patent number: 9980929
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6 and R7 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: August 22, 2017
    Date of Patent: May 29, 2018
    Assignee: Hoffman-La Roche Inc.
    Inventors: Benoit Hornsperger, Roberto Iacone, Bernd Kuhn, Hans P. Maerki, Peter Mohr, Michael Reutlinger
  • Patent number: 9968647
    Abstract: The invention provides novel compounds and conjugates of these compounds useful for the delivery of biologically active substances. Further novel design criteria for chemically stabilized siRNA particular useful when covalently attached to a delivery polymer to achieve in vivo mRNA knock down are disclosed therein.
    Type: Grant
    Filed: April 4, 2016
    Date of Patent: May 15, 2018
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Philipp Hadwiger, Torsten Hoffmann, Kerstin Jahn-Hofmann, Eric A. Kitas, David L. Lewis, Peter Mohr, Hans Martin Mueller, Guenther Ott, Ingo Roehl, David B. Rozema
  • Patent number: 9962772
    Abstract: A clamping device for clamping a workpiece or a tool or a tool holder to a machine component of a machine tool, having an axially movable tension rod, a clamping assembly which can be moved by the tension rod between a clamped position and a released position, a spring assembly dedicated to the tension rod with a plurality of series-connected spring units for generating the clamping and draw-in force of the clamping assembly, and a releasing unit by which the clamping assembly can be moved by the tension rod against the force of the spring assembly into the released position. To ensure the most uniform load possible, the axial spring deflection of the spring units is limited by a stop when the spring assembly is compressed.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: May 8, 2018
    Assignee: OTT-JAKOB SPANNTECHNIK GMBH
    Inventors: Josef Greif, Peter Mohr, Bartholomäus Reisacher, Jr.
  • Patent number: 9931700
    Abstract: A clamping device for clamping a workpiece or a tool or a tool holder to a machine component of a machine tool, including an axially movable tension rod, a clamping assembly which can be moved by the tension rod between a clamped position and a released position, a spring assembly dedicated to the tension rod for generating the clamping and draw-in force of the clamping assembly, and a releasing unit by which the clamping assembly can be moved by the tension rod against the force of the spring assembly into the released position. The spring assembly has a minimum of one spring unit with a plurality of flexible spring members disposed between a first and a second spring holder, with the first and second spring holders being secured against torsion relative to the tension rod.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: April 3, 2018
    Assignee: OTT-JAKOB SPANNTECHNIK GMBH
    Inventors: Josef Greif, Peter Mohr, Bartholomäus Reisacher, Jr.
  • Publication number: 20180057526
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: November 7, 2017
    Publication date: March 1, 2018
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Benoit HORNSPERGER, Roberto IACONE, Eric A. KITAS, Hans P. MAERKI, Michael REUTLINGER, Peter MOHR
  • Publication number: 20170348257
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6 and R7 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: August 22, 2017
    Publication date: December 7, 2017
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Benoit Hornsperger, Roberto Iacone, Bernd Kuhn, Hans P. Maerki, Peter Mohr, Michael Reutlinger