Patents by Inventor Peter N. Braido

Peter N. Braido has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9913715
    Abstract: A collapsible and expandable stent body includes a generally tubular annulus section, one or more prosthetic valve elements mounted to the stent body, and a cuff attached to the stent body. The prosthetic valve is operative to allow flow in an antegrade direction but to substantially block flow in a retrograde direction. The prosthetic heart valve may include paravalvular leak mitigation features in the form of first and second sealing members. The sealing members are attached to the cuff and extend circumferentially around an abluminal surface of the stent body. The sealing members each have an open side facing in a first axial direction and a closed side facing in an opposite second axial direction. Flow of blood in the second axial direction will tend to force blood into the sealing members and cause the sealing members to billow outwardly relative to the stent body, helping to mitigate paravalvular leak.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: March 13, 2018
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Peter N. Braido, Mina S. Fahim
  • Patent number: 9901447
    Abstract: A prosthetic heart valve includes a stent having an expanded condition and a collapsed condition. The stent includes a plurality of distal cells, a plurality of proximal cells, a plurality of support struts coupling the proximal cells to the distal cells, and at least one support post connected to a plurality of proximal cells. The proximal cells are longitudinally spaced apart from the distal cells. Various strut configurations and connections of the struts to the proximal cells and of the proximal cells to the support post improve stent flexibility and reduce stress in the valve leaflets.
    Type: Grant
    Filed: June 14, 2016
    Date of Patent: February 27, 2018
    Assignee: St. Jude Medical, LLC
    Inventors: Peter N. Braido, Yousef F. Alkhatib, Thomas M. Benson, Aaron J. Chalekian, Ott Khouengboua, Julia A. Schraut
  • Patent number: 9895218
    Abstract: A prosthetic heart valve includes a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end and an aortic section adjacent the distal end, the stent including a plurality of struts. A plurality of commissure features is disposed on the stent and coupled to selected ones of the struts, each commissure feature including a body having a proximal end and a distal end, and at least one eyelet in the body. The heart valve further includes a collapsible and expandable valve assembly including a plurality of leaflets. At least one leaflet is connected to the at least one eyelet and to at least one of the selected ones of the struts via a suture pattern.
    Type: Grant
    Filed: October 27, 2015
    Date of Patent: February 20, 2018
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Yousef F. Alkhatib, Peter N. Braido
  • Publication number: 20180042555
    Abstract: Prosthetic heart devices may be implanted into the heart with a sensor coupled to the device, the sensor being configured to measure physiological data, such as blood pressure, in the heart. Devices that may employ such sensors include prosthetic heart valves and occlusion devices, although sensor systems may be deployed in the heart separate from other implantable devices. The sensors may include a body with different configurations for attaching to the implantable device, such as apertures for sutures or fingers for connecting to structures of the implantable device. The sensors may provide data that allow a determination of aortic regurgitation or other information indicative of function of the implantable device and patient health during and after implantation of the device.
    Type: Application
    Filed: October 6, 2017
    Publication date: February 15, 2018
    Applicant: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Peter N. Braido, Mina S. Fahim, Steven Frederick Anderl, Jason White, Paul E. Ashworth, Morgan Low, Loell Boyce Moon, Neelakantan Saikrishnan
  • Patent number: 9889004
    Abstract: A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent having a proximal end and a distal end, and a valve assembly disposed within the stent, the valve assembly including a plurality of leaflets and a cuff annularly disposed about the stent. The cuff includes a surplus portion capable of forming a sealing structure having a diameter greater than a diameter of the proximal end of the stent when deployed.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: February 13, 2018
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventor: Peter N. Braido
  • Publication number: 20180036121
    Abstract: A prosthetic heart valve includes a stent having a collapsed condition and an expanded condition. The stent includes a plurality of cells, each cell being formed by a plurality of struts, and a plurality of commissure features. The heart valve further includes a valve assembly secured to the stent and including a cuff and a plurality of leaflets, each leaflet being attached to adjacent commissure features and to the stent struts and/or the cuff.
    Type: Application
    Filed: October 18, 2017
    Publication date: February 8, 2018
    Applicant: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Xue Mei Li, Peter N. Braido
  • Patent number: 9867611
    Abstract: An anchoring device for use within a vascular structure includes a head having a first surface and a second surface meeting at a common plane, and an anchor including a shaft having a longitudinal axis, a first end connected at a junction to the first surface of the head, and a free end. A harbor space is bounded by the shaft of the anchor, the first surface of the head, a first theoretical plane perpendicular to the longitudinal axis at a spaced distance from the junction and a second theoretical plane tangential to the head at a point in the common plane. The harbor space has an are sufficient to receive a portion of a stented device therein.
    Type: Grant
    Filed: August 19, 2014
    Date of Patent: January 16, 2018
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Kent J. Smith, Peter N. Braido
  • Publication number: 20180008402
    Abstract: A prosthetic heart valve may include a collapsible and expandable stent extending in a flow direction between a proximal end and a distal end, a cuff attached to an annulus section of the stent and having an outer surface facing in a radial direction orthogonal to the flow direction, a plurality of prosthetic valve leaflets attached to the cuff, and a sealing structure attached to the annulus section of the stent at an inner edge of the sealing structure. The flow direction may be defined from the proximal end toward the distal end. The sealing structure may have an outer edge remote from the inner edge. The sealing structure may have a collapsed condition with the outer edge disposed adjacent the outer surface of the cuff and an expanded condition with the outer edge spaced apart from the outer surface of the cuff.
    Type: Application
    Filed: September 20, 2017
    Publication date: January 11, 2018
    Applicant: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Peter N. Braido, Kent J. Smith, Andrea L. McCarthy, Mina S. Fahim
  • Patent number: 9827091
    Abstract: A prosthetic heart valve includes a stent having a collapsed condition and an expanded condition. The stent includes a plurality of cells, each cell being formed by a plurality of struts, and a plurality of commissure features. The heart valve further includes a valve assembly secured to the stent and including a cuff and a plurality of leaflets, each leaflet being attached to adjacent commissure features and to the stent struts and/or the cuff.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: November 28, 2017
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Xue Mei Li, Peter N. Braido
  • Patent number: 9820851
    Abstract: A prosthetic heart valve is designed to be circumferentially collapsible for less invasive delivery into the patient. At the implant site the valve re-expands to a larger circumferential size, i.e., the size that it has for operation as a replacement for one of the patient's native heart valves. The valve includes structures that, at the implant site, extend radially outwardly to engage tissue structures above and below the native heart valve annulus. These radially outwardly extending structures clamp the native tissue between them and thereby help to anchor the prosthetic valve at the desired location in the patient.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: November 21, 2017
    Assignee: St. Jude Medical, LLC
    Inventor: Peter N. Braido
  • Patent number: 9820852
    Abstract: A prosthetic heart valve may include a collapsible and expandable stent extending in a flow direction between a proximal end and a distal end, a cuff attached to an annulus section of the stent and having an outer surface facing in a radial direction orthogonal to the flow direction, a plurality of prosthetic valve leaflets attached to the cuff, and a sealing structure attached to the annulus section of the stent at an inner edge of the sealing structure. The flow direction may be defined from the proximal end toward the distal end. The sealing structure may have an outer edge remote from the inner edge. The sealing structure may have a collapsed condition with the outer edge disposed adjacent the outer surface of the cuff and an expanded condition with the outer edge spaced apart from the outer surface of the cuff.
    Type: Grant
    Filed: January 21, 2015
    Date of Patent: November 21, 2017
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Peter N. Braido, Kent J. Smith, Andrea L. McCarthy, Mina S. Fahim
  • Publication number: 20170319337
    Abstract: A prosthetic valve assembly for implantation in a patient's circulatory system includes a stent, a valve member coupled to the stent and defining a preferred landing zone relative to anatomical structures in the patient's circulatory system, and at least one marker positioned in a predetermined relationship relative to the landing zone of the valve member, the marker being visually distinguishable from the stent using an imaging technique. By observing the marker, the prosthetic valve assembly may be implanted in the patient so that certain ones of the anatomical structures lie within the landing zone.
    Type: Application
    Filed: July 25, 2017
    Publication date: November 9, 2017
    Applicant: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Peter N. Braido, Gary W. Geiger, Thomas Mark Benson, Steven Frederick Anderl, Aditee Kurane
  • Patent number: 9808201
    Abstract: Prosthetic heart devices may be implanted into the heart with a sensor coupled to the device, the sensor being configured to measure physiological data, such as blood pressure, in the heart. Devices that may employ such sensors include prosthetic heart valves and occlusion devices, although sensor systems may be deployed in the heart separate from other implantable devices. The sensors may include a body with different configurations for attaching to the implantable device, such as apertures for sutures or fingers for connecting to structures of the implantable device. The sensors may provide data that allow a determination of aortic regurgitation or other information indicative of function of the implantable device and patient health during and after implantation of the device.
    Type: Grant
    Filed: August 13, 2015
    Date of Patent: November 7, 2017
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Peter N. Braido, Mina S. Fahim, Steven Frederick Anderl, Jason White, Paul E. Ashworth, Morgan Low, Loell Boyce Moon, Neelakantan Saikrishnan
  • Publication number: 20170312075
    Abstract: A prosthetic heart valve having a cuff attached to a stent provides a seal for preventing paravalvular leakage. The cuff may be constructed from known sealing materials to fill in and around paravalvular leakage gaps, while continuously collapsing down into a low profile volume within the stent. The cuff is coupled circumferentially about the stent by members which may be in the nature of dimension and/or shape memory material having a tensioned and relaxed state. The members may be in the form of elongated elastic members or coiled members. When in the tensioned state, the cuff is located within the stent volume to provide a low profile prosthetic heart valve. Upon relaxing of the members, the cuff is pulled over the abluminal surface of the stent to form a cuff seal circumscribing the stent for preventing paravalvular leakage.
    Type: Application
    Filed: July 14, 2017
    Publication date: November 2, 2017
    Applicant: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Mina S. Fahim, Peter N. Braido
  • Publication number: 20170296337
    Abstract: A collapsible prosthetic heart valve includes a collapsible and expandable stent and a collapsible and expandable valve assembly. The stent has a proximal end and a distal end. A plurality of commissure points is disposed on the stent. The valve assembly is disposed within the stent and includes a plurality of leaflets. Each leaflet has a free edge. An end portion of the free edge of each leaflet is folded and sutured to a corresponding one of the plurality of the commissure points.
    Type: Application
    Filed: June 28, 2017
    Publication date: October 19, 2017
    Applicant: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Yousef F. Alkhatib, Peter N. Braido
  • Patent number: 9775707
    Abstract: A collapsible prosthetic heart valve includes a stent and a valve assembly. The stent has an annulus section with a relatively small cross-section, and an aortic section with a relatively large cross-section. The valve assembly, including a cuff and a plurality of leaflets, is secured to the stent in the annulus section such that the valve assembly can be entirely deployed in the native valve annulus and function as intended while at least a portion of the aortic section is held by the delivery device in a manner that allows for resheathing. The configuration of the prosthetic valve is such that the valve leaflets can fully coapt and the valve can function properly even when the stent and/or valve assembly become distorted upon deployment or use.
    Type: Grant
    Filed: April 17, 2015
    Date of Patent: October 3, 2017
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Yousef F. Alkhatib, Peter N. Braido
  • Publication number: 20170273783
    Abstract: A prosthetic heart valve may include a stent body with a plurality of cells arranged in circumferential rows and a cuff attached to the stent. A leaflet attachment panel may be attached to and span a portion of one of the cells. A prosthetic valve element, such as a leaflet having a belly, may be mounted to the leaflet attachment panel. The leaflet attachment panel may not be integral with the stent body. A reduced overlap area may be defined between a proximal end of the stent body and a proximalmost point of attachment of the leaflet belly to the cuff. The reduced overlap area may have a size dependent upon the circumferential row of cells the leaflet attachment panel is attached to and a position of the portion of the leaflet attachment panel to which the leaflet is mounted. Alternately, the leaflet may be attached directly to the stent.
    Type: Application
    Filed: June 7, 2017
    Publication date: September 28, 2017
    Applicant: StJude Medical, Cardiology Division, Inc.
    Inventors: Peter N. Braido, Kent J. Smith
  • Publication number: 20170266000
    Abstract: A prosthetic heart valve includes a collapsible and expandable stent and a plurality of commissure features disposed on the stent. A collapsible and expandable valve assembly includes a plurality of leaflets connected to the plurality of commissure features, each commissure feature including a body having a proximal end and a distal end. A plurality of eyelets is arranged in rows and columns on the body for distributing load from the plurality of leaflets.
    Type: Application
    Filed: June 5, 2017
    Publication date: September 21, 2017
    Applicant: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Peter N. Braido, Jacob John Daly, Julia Ann Schraut
  • Patent number: 9757230
    Abstract: A prosthetic heart valve having a cuff attached to a stent provides a seal for preventing paravalvular leakage. The cuff may be constructed from known sealing materials to fill in and around paravalvular leakage gaps, while continuously collapsing down into a low profile volume within the stent. The cuff is coupled circumferentially about the stent by members which may be in the nature of dimension and/or shape memory material having a tensioned and relaxed state. The members may be in the form of elongated elastic members or coiled members. When in the tensioned state, the cuff is located within the stent volume to provide a low profile prosthetic heart valve. Upon relaxing of the members, the cuff is pulled over the abluminal surface of the stent to form a cuff seal circumscribing the stent for preventing paravalvular leakage.
    Type: Grant
    Filed: May 15, 2015
    Date of Patent: September 12, 2017
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Mina S. Fahim, Peter N. Braido
  • Patent number: 9744034
    Abstract: A prosthetic valve assembly for implantation in a patient's circulatory system includes a stent, a valve member coupled to the stent and defining a preferred landing zone relative to anatomical structures in the patient's circulatory system, and at least one marker positioned in a predetermined relationship relative to the landing zone of the valve member, the marker being visually distinguishable from the stent using an imaging technique. By observing the marker, the prosthetic valve assembly may be implanted in the patient so that certain ones of the anatomical structures lie within the landing zone.
    Type: Grant
    Filed: February 21, 2014
    Date of Patent: August 29, 2017
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Peter N. Braido, Gary W. Geiger, Thomas Mark Benson, Steven Frederick Anderl, Aditee Kurane