Abstract: The present invention provides methods for determining the likelihood and/or severity of GvHD and the likelihood of the occurrence of transplant related mortality.

Abstract: An illuminator (1) is manufactured by embossing an aluminium preform to provide a structured substrate base (21) with cavities (25) for LEDs and recesses (26) for tracks. The substrate is anodised to provide an aluminium oxide insulating layer (30) over the structured surface. A metal layer (35) is then applied over the insulating layer (30), and this is etched to leave metal pads in the cavities and tracks in the recesses (26). LEDs (50) are placed in the cavities and they are wire-bonded to the exposed metal tracks. This manufacturing method allows versatility in choice of configuration of 5 illuminator by simple embossing a desired substrate shape. Also, the anodisation provides an excellent and durable insulating layer, which has the major benefit of being conformal with the structured surface.

Abstract: An embossing master (20) is produced by successively applying epoxy layers (2, 10) over a silicon substrate (1) and selectively exposing them to UV to cross-link according to a pattern. Non-exposed epoxy is developed away to leave a pattern of cured epoxy at each level. This provides a multi-level master, with a desired 3D configuration. The master (20) is then used to emboss a polymer blank to provide a substrate (80) and a different master is used to emboss a blank to provide a superstrate (90). The substrate (80) has aligned socket and channel grooves (80, 81) and the superstrate (90) has a socket groove (91). When the superstrate is mated with the substrate, there is a socket for receiving a fluidic capillary or a detection waveguide. The capillary or waveguide is aligned with the channel for optimum fluidic flow or optical detection.

Abstract: A heat reflection device for footwear includes a first layer of fluid-impervious material, a second layer of fluid-impervious material and a sac arranged between the first and second layers. The sac contains a heat reflective material therein. In use the device is positioned in relation to the sole of the footwear so that at least some heat conducted or converted through the sole is reflected away from the foot of the wearer of the footwear. The heat reflective material may be a mixture of heat reflective powder or particulate, thickening agent and fluid. The heat reflective powder or particulate may be one or a combination of two or more materials selected from titanium dioxide, zirconium and zinc oxide.

Abstract: An adjustable and versatile shelving system for storing articles in the cargo box of a pickup truck in an efficient manner. Brackets which support load bearing members are adjustably mounted to side rails which are connected to the sidewalls of the cargo box. The connection between the brackets and the side rails enable the height of the shelf above the floor of the cargo box to be adjustable within a range of heights. An additional shelf located a spaced distance above the first shelf can be supported by inverting some of the brackets which are connected to the side rails. The brackets can also be connected to the side rails in a manner which provides a surface for securing vertically-oriented side planks above the cargo box sidewalls to temporarily extend the cargo box sidewalls. A knock down tool chest can be provided on the shelf to store tools in a secure manner, or it can be collapsed to provide extra open shelf storage space.

Abstract: A solar-powered lighting system suitable for signs or hoardings (10), navigation beacons or as an emergency supply for hotels, cinemas, hospitals or other services.The system incorporates solar cell arrays (17) which generate electricity which is stored in batteries (22). A sensing circuit (14) selectively connects the batteries (22) to lights (14). A timing/switching circuit (32), (32a) may be provided to selectively connect the lights (14) to a mains supply (30).