Abstract: This invention relates to gels encapsulating organometallic reagents, particularly organolithium reagents. The invention also relates to methods of making said gels and methods of using said gels. The gels are particularly useful in organic synthesis being easier to handle than the organometallic reagent solutions typically used.

Abstract: The present disclosure is directed towards aligning a photonic integrated circuit (PIC) through providing a PIC with a marker waveguide, wherein a marker waveguide is a waveguide having: a first end located at the edge of the PIC wherein the first end is coupled to an edge coupling; and a second end coupled to a grating coupler or a device coupler, wherein: the grating coupler or device coupler is configured to receive light and couple the light to the waveguide to illuminate the waveguide to facilitate the correct alignment of the edge coupler to an external component.

Abstract: A breathing assistance apparatus is configured with features that improve serviceability of the apparatus. The apparatus can include animations to provide instruction regarding correcting easily-identified fault conditions and to provide instruction regarding routine maintenance routines. The apparatus also can be configured with top level control menus that are obscured in a manner to limit manipulation of the top level control elements by unauthorized users.

Abstract: A method of carrying out mass spectrometry, comprising: using an electrostatic or electrodynamic ion trap to contain a plurality of ions, each ion having a mass to charge ratio, the ions having a first plurality of mass to charge ratios, each ion following a path within the electrostatic or electrodynamic ion trap having a radius; and for each of a second plurality of the mass to charge ratios: modulating the radii of the ions in a mass to charge ratio-dependent fashion dependent upon the mass to charge ratio; fragmenting the ions thus modulated in a radius-dependent fashion; and determining a mass spectrum of the ions.

Abstract: Systems, methods, and apparatuses for implementing a behavioral responsive adaptive context engine for emotionally-responsive experiences are disclosed.

Abstract: The present invention provides a breathing assistance apparatus that has a convenient and effective method of cleaning internal conduits inside the apparatus. The breathing assistance apparatus is preferably a gases supply and humidification device. The cleaning method is a method of disinfection that is automated so minimal training is required to disinfect in particular an internal elbow conduit within the device. It is therefore not necessary to dismantle the gases supply and humidification device, therefore, inadvertent damage to the internal parts of the device is avoided. The present invention also provides a method of disinfecting a heated breathing conduit and a patient interface.

Abstract: A latch system for a vehicle includes a synchronizer and a lock unit. The synchronizer is configured to block and allow release of a number of latches of the vehicle such that some latches are blocked from being released if other latches are already released. The lock unit is configured to block selectively the release of the number of latches.

Abstract: Disclosed herein are methods of cancer treatment comprising administration of a natural killer (NK) cell or cell line in combination with an IL-6 antagonist, such as an antibody to IL-6 or its receptor, especially for treatment of cancer expressing IL-6 receptors and in which checkpoint inhibitory receptors, such as PDL-1 and/or PDL-2 are expressed/upregulated during disease.

Abstract: There is accordingly provided a device for measuring a person's ventilation including oxygen consumption. The device includes a breathing conduit with at least one sensor sampling port. The device includes a dehumidification conduit extending from the sensor sampling port towards a sensor. The dehumidification conduit has a proximal end portion flush with the sensor sampling port. The dehumidification conduit has a longitudinal axis about which the proximal end portion thereof extends. The breathing conduit is shaped to promote a flow of air adjacent the sensor sampling port in one or more directions perpendicular to the longitudinal axis.

Abstract: A surround for protecting an acoustic device for sending and/or receiving acoustic signals positioned therein from impact as the surround is rolled along an interior surface of a fluid-containing pipeline, the surround comprising: a shell comprising an exterior segment configured to roll along the interior surface, the exterior segment defining at least one acoustic aperture configured to allow the passage of acoustic signals therethrough; and a lattice configured between the exterior segment and the acoustic device, the lattice comprising a plurality of unit cells, each unit cell defining an opening, wherein the plurality of unit cells are interconnected and define a plurality of openings, wherein the plurality of openings allow fluid to move between the interior of the surround and the exterior of the surround and enable the passage of the acoustic signals transmitted and/or received by the acoustic device such that the surround reduces the diminution of the quality and/or strength of the acoustic signals.

Abstract: The gases temperature supplied to a patient when the patient is undergoing treatment such as oxygen therapy or positive pressure treatment for conditions such as Obstructive Sleep Apnea (OSA) or Chronic Obstructive Pulmonary Disease (COPD) is often measured for safety and to enable controlling of the humidity delivered to the patient. The invention disclosed is related to measurement of properties, particularly temperature (thermistor), of gases flowing through a heated tube, supplying gases to a patient, which utilises the heating wire within the tube.

Abstract: The breathing assistance apparatus of the present invention includes a manifold that is provided with or retrofittable to gases supply and humidifying devices. The manifold allows gases from an oxygen concentrator to be combined with the flow through a gases supply and humidifying device, most usually air. The combined output of oxygen and other breathing gases (air) is then humidified. The breathing assistance apparatus and manifold of the present invention provides a safe method to add oxygen to the input air stream of a gases supply and humidifying device and reduces the amount of accumulation of oxygen within the gases supply device, reducing fire risk should sparking occur within the device.

Abstract: A breathing assistance apparatus is configured with features that improve serviceability of the apparatus. The apparatus can include animations to provide instruction regarding correcting easily-identified fault conditions and to provide instruction regarding routine maintenance routines. The apparatus also can be configured with top level control menus that are obscured in a manner to limit manipulation of the top level control elements by unauthorized users.

Abstract: A pack comprising: a dispenser for anaerobically curable composition; and anaerobically curable composition held within the dispenser. The dispenser has (a) a reservoir in which anaerobically curable composition is held, the reservoir having an outlet through which the anaerobically curable composition can be dispensed; (b) a dispensing pump for pumping the anaerobically curable composition from the reservoir out through the outlet. The reservoir and pump together form an airless pump assembly. An applicator with an applicator surface, for example a roller, is in communication with the outlet, the applicator for applying to a substrate the anaerobically curable composition that is dispensed by the pump from the reservoir out through the outlet. The pack provides a convenient way of forming of applying anaerobically curable composition in a thin even layer.

Abstract: Described is a respiratory therapy system that comprises a respiratory therapy apparatus that is configured to provide a flow of breathable gas at, at least a first pressure and a second pressure to a patient. The respiratory therapy apparatus comprises a flow generator configured to provide the flow of breathable gas, a controller, coupled to a trigger sensor, to control respiratory therapy apparatus operations, a breathing conduit assembly that conveys the breathable gas to a patient via a patient interface, a trigger that produces a signal detectable by the trigger sensor. The controller is configured to control the flow generator to provide the flow of breathable gas at, at least the first pressure or the second pressure based on detection of the signal from the trigger.

Abstract: The catheter probe comprises a catheter tip and a catheter body. The catheter tip comprises a plurality of channels for housing a plurality of optical sensors. Each one of said plurality of optical sensors comprises a ferrule comprising a via, a microlens aligned with said via and attached to said ferrule and an optical fiber for optically coupling said microlens to a monitoring means.

Abstract: A breathing assistance apparatus and method of controlling a breathing assistance apparatus is disclosed. Particularly, the breathing assistance apparatus is controlled such that it has a drying cycle to enable drying of the tubing that supplies gases to a user and prevent the harbouring of pathogens within the tube. The drying cycle is preferably operated automatically by internal controllers in the apparatus. However, it may be manually activated by pressing a button on the apparatus. The drying cycle is preferably activated at the end of a user's treatment session.

Abstract: Systems and method of wrapping an object are disclosed. An object wrapping system includes a contractible loop, a positioning system, and a wrapping material system. The contractible loop is configured to be deployed in an expanded position and a contracted position. The positioning system is configured to position an object in alignment with an aperture defined by the contractible loop. The wrapping material system is configured to position a wrapping material between the object and the aperture. The positioning system is configured to move the object into the wrapping material and through the aperture when the contractible loop is deployed in the expanded position. The contractible loop is configured to deploy into the contracted position to at least partially close the wrapping material around the object.