Abstract: Provided herein are intranasal fluid delivery devices and apparatus comprising a dispensing tip a shot chamber carrying a fluid, the shot chamber having a diaphragm at one end and a plunger at the other end, and an actuator connected to a push rod moveable toward the shot chamber.

Abstract: Disclosed herein, are compositions, methods, systems, and apparatus for collecting biological material from the nasal cavity of a subject or the olfactory region of a subject's nasal cavity. In some embodiments, the biological material is collected from a targeted sub-region of the nasal cavity, such as a targeted sub-region of the olfactory region, wherein such biological material is specific to the targeted sub-region. In some embodiments, the biological material collected from a targeted sub-region is preserved according to its localization. In some embodiments, the biological material comprises cerebrospinal fluid, one or more microbes of the patient's microbiome, one or more components of the patient's metabolome, one or more pathogens, and/or one or more biomarkers of interest. In some embodiments, a specific formulation is delivered to the region in the nasal cavity for facilitating biological material collection located therein.

Abstract: Provided herein are intranasal fluid delivery devices and apparatus comprising a dispensing tip a shot chamber carrying a fluid, the shot chamber having a diaphragm at one end and a plunger at the other end, an actuator connected to a push rod moveable toward the shot chamber, and a sheath covering at least a distal end of the dispensing tip, wherein the distal end of the dispensing tip is configured to extend from the sheath and into a subject's nasal cavity.

Abstract: Embodiments relate to an intranasal drug delivery device, system, and process. The drug delivery device can have a compliant/flexible soft nib. The drug delivery device can have an actuator and shot chamber. The drug delivery device can have a non-air interface mechanically pressurized fluid reservoir. The drug delivery device can have a facial or device recognition application to prevent intentional or unintentional misuse.

Abstract: Provided herein are intranasal fluid delivery devices and apparatus comprising a dispensing tip a shot chamber carrying a fluid, the shot chamber having a diaphragm at one end and a plunger at the other end, and an actuator connected to a push rod moveable toward the shot chamber.

Abstract: Embodiments relate to an intranasal drug delivery device, system, and process. The drug delivery device can have a compliant/flexible soft nib. The drug delivery device can have an actuator and shot chamber. The drug delivery device can have a non-air interface mechanically pressurized fluid reservoir. The drug delivery device can have a facial or device recognition application to prevent intentional or unintentional misuse.

Abstract: Disclosed herein, are compositions, methods, systems, and apparatus for collecting biological material from the nasal cavity of a subject or the olfactory region of a subject's nasal cavity. In some embodiments, the biological material is collected from a targeted sub-region of the nasal cavity, such as a targeted sub-region of the olfactory region, wherein such biological material is specific to the targeted sub-region. In some embodiments, the biological material collected from a targeted sub-region is preserved according to its localization. In some embodiments, the biological material comprises cerebrospinal fluid, one or more microbes of the patient's microbiome, one or more components of the patient's metabolome, one or more pathogens, and/or one or more biomarkers of interest. In some embodiments, a specific formulation is delivered to the region in the nasal cavity for facilitating biological material collection located therein.

Abstract: Embodiments relate to an intranasal drug delivery device, system, and process. The drug delivery device can have a compliant/flexible soft nib. The drug delivery device can have an actuator and shot chamber. The drug delivery device can have a non-air interface mechanically pressurized fluid reservoir. The drug delivery device can have a facial or device recognition application to prevent intentional or unintentional misuse.

Abstract: An actuating device is provided for moving a closure panel between an open position spaced apart from a vehicle body and a closed position abutting the vehicle body to close an access opening thereof. The actuating device includes a telescopic arm having a first member coupled to one of the closure panel and the vehicle body and a second member coupled to the other of the closure panel and the vehicle body. The first and second members are slidable relative to one another to move the actuating device between a retracted position corresponding with the closed position and an extended position corresponding with the open position. A screw is rotatable relative to the first member. The screw includes a cavity formed therewithin. A nut is secured to the second member and threadingly engages the screw such that rotation of the screw moves the second member towards and away from the first member to move the actuating device between the respective retracted and extended positions.

Abstract: A power drive assembly (110) for controlling movement of a closure panel (102, 105) of a vehicle includes a closure panel (102, 105) that moves relative to the vehicle between open and closed positions, and a latch (108, 115) for cinching the closure panel (102, 105) to the vehicle. The drive assembly (110) includes an actuator (134), a first torque output (136) coupled to effect movement of the closure panel (102, 105), a second torque output (138) coupled to the latch (115), and a clutch assembly (114, 150) coupled between the actuator (134) and the torque outputs (136, 138) for selectively transferring torque between the actuator (134) and the torque outputs (136, 138).

Abstract: A vehicle door for fitting to a vehicle body includes a vehicle door frame, and a pivot arm coupled to the door frame. The door frame includes an upper portion, a lower portion, and a pair of opposite sides extending between the upper and lower portions. The pivot arm is coupled to the door frame adjacent one of the opposite sides, and includes a pair of opposite ends. One of the ends of the pivot arm includes a first hinge for pivotally coupling the pivot arm to the vehicle body about a first pivot axis. The other end includes a second hinge pivotally coupling the door frame to the pivot arm about a second pivot axis.

Abstract: A power drive assembly (110) for controlling movement of a closure panel (102, 105) of a vehicle includes a closure panel (102, 105) that moves relative to the vehicle between open and closed positions, and a latch (108, 115) for cinching the closure panel (102, 105) to the vehicle. The drive assembly (110) includes an actuator (134), a first torque output (136) coupled to effect movement of the closure panel (102, 105), a second torque output (138) coupled to the latch (115), and a clutch assembly (144, 150) coupled between the actuator (134) and the torque outputs (136, 138) for selectively transferring torque between the actuator (134) and the torque outputs (136, 138).

Abstract: A pair of manually-manipulatable spring-loaded buttons are accessible outwardly of the side walls of a pair of respective vise brackets secured beneath the table of a portable foldable workbench. When the buttons are pressed laterally inwardly, respective latching mechanisms are released to enable the workbench to be raised from a lowered storage position into an erected working position, and vice-versa. The buttons facilitate a rapid movement of the workbench from one position to another, and the buttons are conveniently located on the workbench for improved ergonomics.

Abstract: A pair of manually-manipulatable spring-loaded buttons are accessible outwardly of the side walls of a pair of respective vise brackets secured beneath the table of a portable foldable workbench. When the buttons are pressed laterally inwardly, respective latching mechanisms are released to enable the workbench to be raised from a lowered storage position into an erected working position, and vice-versa. The buttons facilitate a rapid movement of the workbench from one position to another, and the buttons are conveniently located on the workbench for improved ergonomics.