Patents by Inventor Peter Probst

Peter Probst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8263089
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: September 11, 2012
    Assignee: Corixa Corporation
    Inventors: Ajay Bhatia, Yasir A. W. Skeiky, Peter Probst
  • Publication number: 20120114684
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Application
    Filed: September 30, 2011
    Publication date: May 10, 2012
    Applicant: CORIXA CORPORATION
    Inventors: Ajay Bhatia, Yasir A.W. Skeiky, Peter Probst
  • Publication number: 20110300206
    Abstract: The present invention relates to compositions comprising proteins or polynucleotides of Chlamydia sp., in particular combinations of proteins or polynucleotides encoding them, and methods for the use of the proteins or polynucleotides in the treatment, prevention and diagnosis of Chlamydia infection.
    Type: Application
    Filed: December 21, 2010
    Publication date: December 8, 2011
    Applicants: GlaxoSmithKline Biologicals, sa, Corixa Corporation
    Inventors: Mark ALDERSON, Ajay BHATIA, Yves LOBET, Brenda MAISONNEUVE, Jean-Francois L. MAISONNEUVE, Martine MARCHAND, Pascal METTENS, Florence Bernadette NOZAY, Peter PROBST, Yasir A. SKEIKY, Samira H. SKEIKY
  • Patent number: 8052975
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: November 8, 2011
    Assignee: Corixa Corporation
    Inventors: Ajay Bhatia, Yasir A. W. Skeiky, Peter Probst
  • Publication number: 20110142872
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Application
    Filed: October 30, 2007
    Publication date: June 16, 2011
    Applicant: CORIXA CORPORATION
    Inventors: Ajay Bhatia, Yasir A.W. Skeiky, Peter Probst
  • Publication number: 20100239579
    Abstract: Provide herein are fusion polypeptides that comprise a CD47 extracellular domain or a variant thereof that is fused to a Fc polypeptide. The fusion polypeptides are useful for treating an immunological disease or disorder in a subject according to the methods described herein. The fusion polypeptides are capable of suppressing immunoresponsiveness of an immune cell, inhibiting production of proinflammatory cytokines, including inhibiting immune complex-induced production of cytokines.
    Type: Application
    Filed: January 14, 2010
    Publication date: September 23, 2010
    Applicant: VIRAL LOGIC SYSTEMS TECHNOLOGY CORP.
    Inventors: Craig A. Smith, Steven Wiley, Ajamete Kaykas, Peter Probst
  • Publication number: 20100172927
    Abstract: Methods and compositions for the treatment or prevention of ocular Chlamydia trachomatis infection. Compositions comprise one or more Chlamydia trachomatis proteins, immunogenic fragments thereof or polynucleotides encoding such proteins or fragments.
    Type: Application
    Filed: October 3, 2007
    Publication date: July 8, 2010
    Inventors: Mark Alderson, Rhea Coler, Yves Lobet, Jean-Francois L. Maisonneuve, Pascal Mettens, Peter Probst, Steven Reed
  • Publication number: 20090117112
    Abstract: The poxvirus proteins designated A41L and 130L bind to three receptor-like protein tyrosine phosphatases (RPTP), leukocyte common antigen related protein (LAR), RPTP-?, and RPTP-?, that are present on the cell surface of immune cells. When a host is infected with the poxvirus, binding of A41L to cell surface proteins on the host cells results in suppression of the immune response. The present invention provides agents such as antibodies, and antigen-binding fragments thereof, small molecules, aptamers, small interfering RNAs, and peptide-IgFc fusion polypeptides that interact with one or more of LAR, RPTP-?, and RPTP-? expressed by immune cells or interact with a polynucleotide encoding the RPTP. Also provided are RPTP Ig domain oligomers and Fc fusion polypeptides. Such agents are useful for treating an immunological disorder in a subject according to the methods described herein.
    Type: Application
    Filed: October 6, 2008
    Publication date: May 7, 2009
    Applicant: VIRAL LOGIC SYSTEMS TECHNOLOGY CORPORATION
    Inventors: Craig A. Smith, Steven Wiley, Ajamete Kaykas, Jalal Vakili, Peter Probst
  • Publication number: 20090035296
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Application
    Filed: October 30, 2007
    Publication date: February 5, 2009
    Applicant: CORIXA CORPORATION
    Inventors: Ajay Bhatia, Yasir A. W. Skeiky, Peter Probst
  • Publication number: 20090028887
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Application
    Filed: October 30, 2007
    Publication date: January 29, 2009
    Applicant: CORIXA CORPORATION
    Inventors: Ajay Bhatia, Yasir A.W. Skeiky, Peter Probst
  • Publication number: 20090022755
    Abstract: The present invention relates to compositions comprising proteins or polynucleotides of Chlamydia sp., in particular combinations of proteins or polynucleotides encoding them, and methods for the use of the proteins or polynucleotides in the treatment, prevention and diagnosis of Chlamydia infection.
    Type: Application
    Filed: March 24, 2006
    Publication date: January 22, 2009
    Applicants: GLAXOSMITHKLINE BIOLOGICALS SA, CORIXA CORPORATION
    Inventors: Brenda Barth, Ajay Bhatia, Mark Alderson, Jean-Francois L. Maisonneuve, Yves Lobet, Florence Bernadette Nozay, Martine Marchand, Pascal Mettens, Yasir A. Skeiky, Peter Probst
  • Publication number: 20080317772
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Application
    Filed: October 30, 2007
    Publication date: December 25, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Ajay Bhatia, Yasir A.W. Skeiky, Peter Probst
  • Patent number: 7462357
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: December 9, 2008
    Assignee: Corixa Corporation
    Inventors: Ajay Bhatia, Yasir A. W. Skeiky, Peter Probst
  • Publication number: 20080299142
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Application
    Filed: October 30, 2007
    Publication date: December 4, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Ajay Bhatia, Yasir A.W. Skeiky, Peter Probst
  • Publication number: 20080213264
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Application
    Filed: October 30, 2007
    Publication date: September 4, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Ajay Bhatia, Yasir A. W. Skeiky, Peter Probst
  • Publication number: 20080181918
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Application
    Filed: October 30, 2007
    Publication date: July 31, 2008
    Applicant: CORIXA CORPORATION
    Inventors: Ajay Bhatia, Yasir A. W. Skeiky, Peter Probst
  • Patent number: 7384638
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Grant
    Filed: January 15, 2004
    Date of Patent: June 10, 2008
    Assignee: Corixa Corporation
    Inventors: Ajay Bhatia, Peter Probst, Erika Jean Stromberg
  • Publication number: 20080131431
    Abstract: Provide herein are fusion polypeptides that comprise a CD47 extracellular domain or a variant thereof that is fused to a Fc polypeptide. The fusion polypeptides are useful for treating an immunological disease or disorder in a subject according to the methods described herein. The fusion polypeptides are capable of suppressing immunoresponsiveness of an immune cell, inhibiting production of proinflammatory cytokines, including inhibiting immune complex-induced production of cytokines.
    Type: Application
    Filed: May 15, 2007
    Publication date: June 5, 2008
    Applicant: Viral Logic Systems Technology Corp.
    Inventors: Craig A. Smith, Steven Wiley, Ajamete Kaykas, Peter Probst
  • Publication number: 20070134234
    Abstract: The poxvirus proteins designated A41L and 130L bind to three receptor-like protein tyrosine phosphatases (RPTP), leukocyte common antigen related protein (LAR), RPTP-?, and RPTP-?, that are present on the cell surface of immune cells. When a host is infected with the poxvirus, binding of A41L to cell surface proteins on the host cells results in suppression of the immune response. The present invention provides agents such as antibodies, and antigen-binding fragments thereof, small molecules, aptamers, small interfering RNAs, and peptide-IgFc fusion polypeptides that interact with one or more of LAR, RPTP-?, and RPTP-? expressed by immune cells or interact with a polynucleotide encoding the RPTP. Also provided are RPTP Ig domain oligomers and Fc fusion polypeptides. Such agents are useful for treating an immunological disorder in a subject according to the methods described herein.
    Type: Application
    Filed: September 29, 2006
    Publication date: June 14, 2007
    Applicant: Viral Logic Systems Technology Corp.
    Inventors: Craig Smith, Steven Wiley, Ajamete Kaykas, Jalal Vakili, Peter Probst
  • Publication number: 20040234536
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Application
    Filed: June 18, 2004
    Publication date: November 25, 2004
    Applicant: Corixa Corporation
    Inventors: Ajay Bhatia, Yasir A.W. Skeiky, Peter Probst