Abstract: A brake lining arrangement, in particular for a disk brake of a motor vehicle, has a rear plate and a friction lining that is connected to the rear plate. The rear plate has a bearing face on which the friction lining is placed. The rear plate also has a member configured for fastening the friction lining on the bearing face. The friction lining has at least one cutout that is configured as a blind bore. At least one connecting pin is arranged fixedly on the rear plate so as to project from the bearing face. The connecting pin is configured to engage at least substantially without play into the cutout.

Abstract: A brake lining arrangement, in particular for a disk brake of a motor vehicle, has a rear plate and a friction lining that is connected to the rear plate. The rear plate has a bearing face on which the friction lining is placed. The rear plate also has a member configured for fastening the friction lining on the bearing face. The friction lining has at least one cutout that is configured as a blind bore. At least one connecting pin is arranged fixedly on the rear plate so as to project from the bearing face. The connecting pin is configured to engage at least substantially without play into the cutout.

Abstract: A method for preparing a sample of biological materials containing target cells and accompanying cells for extracting nucleic acids of the target cells includes accumulating the target cells of the sample by separating the target cells or the accompanying cells from the sample. The method also includes digesting the target cells via chemical and/or physical lysis in order to produce a target cell lysate containing the nucleic acids of the target cells. The method furthermore includes purifying the nucleic acids from the target cell lysate in order to extract the nucleic acids of the target cells.

Abstract: A device configured for lysing a sample includes a holding element configured to hold an energy-transmitting element such that the holding element lies around the held part of the energy-transmitting element and envelops the held part of the energy-transmitting element and/or that the holding element lies against the held part of the energy-transmitting element. The holding element is further configured to cause lysis with the energy-transmitting element when the holding element is immersed into the sample to be subjected to lysis or comes into contact with the sample to be subjected to lysis. A method includes inserting the energy-transmitting element into the holding element. A system configured for lysing a sample by way of ultrasound includes the device and the energy transmitting element.

Abstract: An apparatus for hermetically sealed storage of liquids for a microfluidic system includes at least one cavity and at least one sealing cone. A connection to the microfluidic system is established via the at least one sealing cone. Additionally, the at least one sealing cone is configured to close the at least one cavity.

Abstract: A method is disclosed for concentrating sample constituents and for multiplying nucleic acids from a biological sample which are containing in the sample constituents. The nucleic acids are amplified on the same filter on which the sample constituents are also separated off.

Abstract: A method for preparing a sample of biological materials containing target cells and accompanying cells for extracting nucleic acids of the target cells includes accumulating the target cells of the sample by separating the target cells or the accompanying cells from the sample. The method also includes digesting the target cells via chemical and/or physical lysis in order to produce a target cell lysate containing the nucleic acids of the target cells. The method furthermore includes purifying the nucleic acids from the target cell lysate in order to extract the nucleic acids of the target cells.

Abstract: A method for producing a brake lining, including a multiplicity of fibers, for a braking device.

Abstract: A microfluidic storage device for pre-storing a fluid includes a first substrate, a second substrate, and a membrane. The first substrate has a recess formed in a first surface. The second substrate has a second surface formed to form fit with the first surface at least in subregions outside the recess. The membrane is arranged between the first and second substrates and is in contact with the first and second surfaces in regions outside the recess. In the region of the recess, the membrane is configured to line the recess so that a volume region inside the recess, between the membrane and the second substrate, can be filled with the fluid. The first substrate, the membrane, and the second substrate are configured to be joined together at least in subregions, outside the recess, in which the membrane is in contact with the first and second surfaces.

Abstract: A method for digesting biological cells in a reaction container includes treating the cells with pressure pulses. The pressure pulses are generated by at least one eddy current actuator in conjunction with an electric conductor arranged on or in the reaction container.

Abstract: A microfluidic cell for the dielectrophoretic separation, accumulation, and/or lysis of polarizable bioparticles, including an interdigital electrode system composed of two electrode groups having interdigitated electrodes, and a micromixer having microchannels and microelevations. The interdigital electrode system and the micromixer are situated on the same side of the cell to improve the separation, accumulation, and/or lysis characteristics. Moreover, also described is a microfluidic system which includes such a microfluidic cell, and use thereof, and a method for separating, accumulating, and/or lysing polarizable bioparticles.

Abstract: A microvalve, in particular for a micropump, is described, which includes a valve member which is adjustable between an open position and a closed position, in contact with a valve seat in its closed position. The valve seat is made of a polymer material. A micropump and a manufacturing method are also described.

Abstract: A microfluidic chromatography element in which all components are situated in one plane and the mobile phase perfuses the stationary phase laterally.

Abstract: A device configured for lysing a sample includes a holding element configured to hold an energy-transmitting element such that the holding element lies around the held part of the energy-transmitting element and envelops the held part of the energy-transmitting element and/or that the holding element lies against the held part of the energy-transmitting element. The holding element is further configured to cause lysis with the energy-transmitting element when the holding element is immersed into the sample to be subjected to lysis or comes into contact with the sample to be subjected to lysis. A method includes inserting the energy-transmitting element into the holding element. A system configured for lysing a sample by way of ultrasound includes the device and the energy transmitting element.

Abstract: A method and encapsulation of a sensitive mechanical component structure in one embodiment includes a semiconductor substrate, and a film covering a component structure on the substrate, said film including at least one polymer layer, and at least one cavity formed between the component structure and the film, wherein at least one through contact penetrates through the film.

Abstract: An apparatus for hermetically sealed storage of liquids for a microfluidic system includes at least one cavity and at least one sealing cone through which a connection to the microfluidic system is configured to be established and which closes the cavity.

Abstract: A microfluidic storage device for pre-storing a fluid includes a first substrate, a second substrate, and a membrane. The first substrate has a recess formed in a first surface. The second substrate has a second surface formed to form fit with the first surface at least in subregions outside the recess. The membrane is arranged between the first and second substrates and is in contact with the first and second surfaces in regions outside the recess. In the region of the recess, the membrane is configured to line the recess so that a volume region inside the recess, between the membrane and the second substrate, can be filled with the fluid. The first substrate, the membrane, and the second substrate are configured to be joined together at least in subregions, outside the recess, in which the membrane is in contact with the first and second surfaces.

Abstract: A microfluidic component for manipulating a fluid includes a first substrate, a second substrate, and a third substrate that is configured from a resilient material and arranged between the first substrate and the second substrate. At least one first recess that forms a first control chamber is configured on the face of the first substrate facing the third substrate. At least one second recess that forms a fluid channel is configured on the face of the second substrate facing the third substrate. A second control chamber that is spatially separated from the first control chamber and a control channel that connects the first control chamber to the second control chamber are formed in the first substrate. At least one lateral wall of the second control chamber is configured from resilient material and is deformable by an actuator such that the inner volume of the second control chamber decreases.

Abstract: An encapsulation of a sensitive component structure on a semiconductor substrate with a film covering the component structure is disclosed. A cavity for the component structure is provided in the film. A MEMS and a method for encapsulating a sensitive component structure is also disclosed.

Abstract: A method is disclosed for concentrating sample constituents and for multiplying nucleic acids from a biological sample which are containing in the sample constituents. The nucleic acids are amplified on the same filter on which the sample constituents are also separated off.