Abstract: A barrel having a dispensing device for dispensing a fluid, having a fluid reservoir for receiving the fluid, a carrying device having a carrying handle for carrying the fluid reservoir, a valve which is configured to release the fluid from the fluid reservoir when in an actuated state, and a spout which can be connected to the valve for dispensing the fluid released out of the valve. The carrying handle has a recess which forms a receptacle for the spout, the spout can be secured in the receptacle in a carrying state and can be connected to the valve in an operating state.

Abstract: A barrel having a dispensing device for dispensing a fluid, having a fluid reservoir for receiving the fluid, a carrying device with a carrying handle for carrying the fluid reservoir, wherein the carrying handle is movable relative to the fluid reservoir, a valve which is configured to release the fluid from the fluid reservoir when in an actuated state, and a spout which can be connected to the valve for dispensing the fluid released out of the valve. In a connected state in which the spout is connected to the valve, a relative movement of the carrying handle relative to the fluid reservoir leads to an actuation of the valve, while in a non-connected state in which the spout is not connected to the valve, the relative movement of the carrying handle does not lead to actuation of the valve.

Abstract: An implantable medical device implantable in a human or animal heart that carries out the following steps during its operation: a) continuously detecting a cardiac electric signal; b) starting a coagulation timer if the detected cardiac electric signal is indicative for an atrial tachycardia; c) keeping the coagulation timer active during a temporary loss of the cardiac electric signal; and d) stopping the coagulation timer, if the following criteria are fulfilled: i) an amplitude of the cardiac electric signal of a plurality of cardiac intervals being close in time exceeds a presettable significance threshold, and ii) an atrial rate calculated from the plurality of cardiac intervals being close in time is below a predefinable threshold rate indicative for atrial tachycardia, or e) keeping the coagulation timer active for a predefined time period, if the criteria are not fulfilled.

Abstract: The present invention relates to pharmaceutical compositions comprising fixed dose combinations of a DPP-4 inhibitor drug and/or a SGLT-2 inhibitor drug, and metformin XR, processes for the preparation thereof, and their use to treat certain diseases.

Abstract: A method for detecting an error that occurred during data processing, using a computer-implemented monitoring instance. The method provides for a plurality of application software instances executed independently of one another on a non-intrinsically safe computer platform, e.g., for controlling one motor vehicle in each case, to be entangled so that, in the event of a critical error in one application software instance, a reliable and timely error response is triggered in all application software instances. A system for detecting an error that occurred during data processing, to a computer program and a machine-readable storage medium is also described.

Abstract: Method comprising: monitoring whether a network receives an authorization request for establishing a session of an AF with a UE, wherein the authorization request comprises a permanent identifier of the AF, a received temporary identifier of the AF, and a temporary identifier of a UE; if the authorization request is received: forming a key identifier based on the temporary identifier of the UE; retrieving, based on the key identifier, a stored key and a first permanent identifier of the UE; calculating a calculated temporary identifier of the AF based on the permanent identifier of the AF and the stored key; checking whether the calculated temporary identifier of the AF is identical with the received temporary identifier of the AF; inhibiting authorizing the AF for the establishing the session with the UE if the calculated temporary identifier of the AF is not identical with the received temporary identifier of the AF.

Abstract: A serration balloon can have a number of different components and can be made in a number of different manners. One or more longitudinally extending members with periodic raised wedges can be attached to a medical balloon. They can be attached with a fiber coating, a polymer coating, or other methods. A polymer matrix can be used to bond the longitudinally extending member to the surface of the balloon. The fiber coating can be, for example, a thread or mesh that secures the longitudinally extending member to the balloon. The medical balloon can be an angioplasty balloon, such as an off-the-shelf angioplasty balloon.

Abstract: A method for processing sensor data in a control device of a vehicle. The method includes: evaluating sensor data generated by different sensors of the vehicle for detecting its environment, via different evaluation functions which convert at least part of the sensor data as input data into output data, wherein the output data are assigned a priority using an assignment rule based on known insufficiencies of the sensors and/or the evaluation functions and the output data are used according to their priority in order to update an environment model that stores information about objects in the environment of the vehicle; recognizing an insufficiency that differs from the known insufficiencies using at least a part of the sensor data and/or at least a part of the output data; updating the assignment rule based on the recognized insufficiency.

Abstract: A method for checking the integrity of a compute node which is part of a network of compute nodes communicatively connected to one another, and on which at least one portion of a distributed application is executed. The method includes: providing test data for the compute node; generating test results by applying the at least one portion of the distributed application to the provided test data; and checking the integrity of the compute node by comparing the test results to expected results.

Abstract: The present invention relates to the dipeptidyl-peptidase I (DPPI or Cathepsin C) inhibitor of formula (I), which is useful in the prevention and/or treatment of bronchiectasis with certain underlying aetiologies, in the prevention and/or treatment of anti-neutrophil cytoplasmic antibody-associated vasculitis or hidradenitis suppurativa using therapeutically efficacious dosages and to polymorphs of Compound (I) as well as to pharmaceutical compositions comprising Compound (I) and its polymorphs.

Abstract: There is provided an apparatus, method and computer program for causing a first apparatus to: obtain an identifier of a cryptographic key according to a first security communication protocol; signal, to a second apparatus, a first authentication request according to a second security communication protocol, the first authentication request comprising the identifier of the cryptographic key and a first verifying information according to a second security communication protocol, wherein the first verifying information comprises a first value calculated using the cryptographic key; receive, from the second apparatus, an authentication response according to the second security communication protocol, the authentication response comprising a second verifying information according to the second security communication protocol, wherein the second verifying information comprises a second value; and verify the second apparatus for the second security communication protocol using the second value and the cryptographic

Abstract: A current collector and a method for transferring energy from a conductor rail to a vehicle by means of a current collector, the current collector comprising a carrying device, a contact pressing device and a sliding piece which forms a sliding contact surface, the carrying device for mounting the current collector being formed on a vehicle, the contact pressing device being formed such that by means of the contact pressing device, the sliding piece is moveable relative to a conductor rail and pressable against the conductor rail for forming a sliding contact with a contact pressing force in a sliding contact position, the contact pressing device comprising a rocker unit for generating the contact pressing force using a rocker and a spring member, the spring member being rotatable in such a manner that the sliding piece disposed on the rocker is moveable in one direction into the sliding contact position while generating the contact pressing force, the contact pressing device comprising a retaining element wh

Abstract: A method for decomposing and distributing a monolithic application. The method includes: deploying the monolithic application on a data processing device; generating a behavior profile of the monolithic application based on an analysis of the monolithic application during a runtime thereof; determining at least one possible decomposition of the monolithic application into modules based on the generated behavior profile; initiating a deployment of the modules on a distributed system to provide a distributed application; initiating monitoring of a runtime behavior of the distributed application; initiating an optimization of the decomposition and of the deployment of the modules by maximizing a similarity between the monolithic application and the distributed application. A computer program, a device, and a storage medium are also described.

Abstract: The present invention relates to a compound according to formula (I) wherein R1 to R9 are as described herein; and pharmaceutically acceptable salts, stereoisomers, enantiomers, tautomers of the compounds of formula (I) as well as pharmaceutical compositions thereof and their uses in methods of reducing the virulence of bacteria that express AgrA, in methods for preventing or treating diseases caused or exacerbated by bacteria, preferably by Staphylococcus aureus, such as skin or lung infections or atopic dermatitis.

Abstract: A cage can be positioned around a medical balloon, such as an angioplasty balloon, to assist in a medical procedure. The cage can include a plurality of strips, each extending between a set of rings including first and second rings. As the balloon expands, the first and second rings move closer together and allow the strips to expand outward. The cage may have wedge dissectors on the strips.

Abstract: A programming device for programming an implantable medical device for stimulating a human or animal heart, wherein the following steps are performed: a) allowing to select one of at least two electrode lead configurations for stimulating a human or animal heart, wherein the at least two electrode lead configurations comprise a second electrode lead configuration in which at least one electrode lead is connected to an electrode lead port, the electrode lead port being configured to receive an electrode lead for stimulating a second cardiac region or detecting an electric signal at the second cardiac region, wherein the second cardiac region is a part of a ventricular conduction system of the heart, wherein the at least one electrode lead is intended to be implanted or is implanted in the second cardiac region; b) generating and releasing a notification signal if the second electrode lead configuration is selected.

Abstract: A method and system for activating a safety-relevant function of a vehicle is disclosed. The vehicle and/or the system has n ASIL control devices, at least one control device to be monitored and a function control device.

Abstract: A method for checking the plausibility of data of an external environmental sensor system by at least one networked road user. Data of an external data source are received using a communication system of the networked road user. The data include first environmental information, acquired by an external environmental sensor system assigned to the external data source, which represents a first spatial area. The networked road user includes an internal environmental sensor system, having a safe sensor range. Second environmental information is generated using the internal environmental sensor system of the networked road user, wherein the second environmental information originates from a sub-area of the first spatial area. The data of the external environmental sensor system are checked for plausibility depending on the first environmental information and the second environmental information.