Abstract: The invention relates to quinazoline derivatives of formula (I), wherein m is an integer from 1 to 3; R1 represents halogeno or C1-3alkyl; X1 represents —O—; R2 is selected from one of the following three groups: 1) C1-5alkylR3 (wherein R3 is piperidin-4-yl which may bear one or two substituents selected from hydroxy, halogeno, C1-4 alkyl, C1-4hydroxyalkyl and C1-4alkoxy; 2) C2-5alkenylR3 (wherein R3 is as defined hereinbefore); 3) C2-5alkynylR3 (wherein R3 is as defined hereinbefore); and wherein any alkyl, alkenyl or alkynyl group may bear one or more substituents selected from hydroxy, halogeno and amino; and salts thereof; processes for their preparation, pharmaceutical compositions containing a compound of formula (I) or a pharmaceutically acceptable salt thereof as active ingredient. The compounds of formula (I) and the pharmaceutically acceptable salts thereof inhibit the effects of VEGF, a property of value in the treatment of a number of disease states including cancer and rheumatoid arthritis.

Abstract: A method for measuring load performance of a positive displacement motor (PDM) test coupon. The test coupon includes a partial length of a PDM stage and is received inside a sealable test chamber. In some embodiments, the test coupon may be cut from a failed PDM stage. The test chamber is filled with test fluid. In some embodiments, the test fluid may be drilling fluid sampled from a live well. Rotation of the rotor on the test coupon actuates rotation of the stator. A braking torque is applied to the stator rotation, enabling evaluation of, for example, fatigue load performance of test coupon. Additional embodiments comprise the rotor axis and the stator axis being offset in order to simulate rotor/stator eccentricity in a full size PDM stage.

Abstract: Embodiments disclosed herein provide compression/distraction methods and tools useful for fitting a spinal stabilization system in a patient through minimally invasive surgery. The spinal stabilization system may comprise screws anchored in vertebrae. The vertebrae may need to be compressed or distracted. One embodiment of an instrument disclosed herein may comprise a shaft for engaging one of the screws through an extender sleeve. A driver may engage another screw through an opening of the instrument. Through this engagement, a surgeon may use the rack and pinion of the instrument to compress or distract one or more levels of the vertebrae in a parallel motion, which can be advantageous clinically in certain situations.

Abstract: Example embodiments relates to method and systems to restore content of a volume at a given point in time.

Abstract: A torque transmission comprising input and output shaft adapters. Pins disposed on an outer surface of the input shaft adapter. Each pin provides a curved pin portion oriented generally perpendicular to the input shaft adapter's longitudinal axis. The output shaft adapter provides a recess with a plurality of notches formed in the recess's periphery, wherein the recess is shaped and sized such that when the input shaft adapter is received inside the recess, each pin is received into a corresponding notch. The torque transmission further comprises torsional bearings interposed between the pins and the notches, each torsional bearing providing a curved laminate portion such that the curve laminate portions contact the curved pin portions when the pins are received into their corresponding notches. The torsional bearings may further provide flat laminate portions that contact the notch when the pins are received into the notches.

Abstract: A connector for connecting control conductors provided in conduits also containing power conductors, the connector including a first guide for receiving a first at least one control conductor provided in a first conduit also containing at least one power conductor, a second guide for receiving a second at least one control conductor provided in a second conduit also containing at least one power conductor, at least one jumper for electrically connecting the first at least one control conductor and the second at least one control conductor and a housing for containing the first guide, second guide and the at least one jumper.

Abstract: A method for browsing a collection of digital images on a soft-copy display comprising: receiving a collection of digital images; interactively user selecting a digital image using a user interface; determining a plurality of subsets of the digital images, wherein each subset shares a common category with the selected digital image; and displaying the subsets of digital images on the soft-copy display, together with the selected digital image.

Abstract: A flywheel apparatus that magnetically unloads a top rotor bearing is described. The apparatus includes a flywheel housing, a rotor with a vertical axis of rotation that includes a magnetic material, a magnet configured to apply a desired upward off-loading force along the vertical axis of rotation, an upper bearing connected to an upper shaft of the rotor, and a bearing housing disposed between the upper bearing and the flywheel housing that substantially prevents downward axial motion of the upper bearing. The magnet includes an electromagnet. A force sensor is used to measure a force on the upper bearing which is provided as input to a controller that updates the current to the electromagnet. The rotor is maintained in a fixed axial position and a spring disposed below a lower bearing absorbs axial dimension growth of the rotor.

Abstract: The invention relates to a process for preparing a meat-analogue food product. More specifically, the present invention relates to a process for preparing a meat-analogue food product having the appearance and the texture of meat and also relates to a meat-analogue food product obtained by the process.

Abstract: In some embodiments, a method is disclosed for manufacturing an undercut stator from a unitary cylindrical workpiece using broaching techniques. In other embodiments, methods are disclosed for manufacturing undercut and non-undercut stators using friction welding techniques to conjoin threaded end sections to stator sections having helical pathways formed therein.

Abstract: Methods, systems and articles of manufacture for creating an electronic spreadsheet using a web-based spreadsheet application. A web-server hosting a web-based spreadsheet website comprises one or more computer(s) having at least one computer processor, memory, data storage and a network communication device (e.g. a network adapter). The web-server is configured to transmit a spreadsheet web application to a user computing device (e.g. a personal computer, smartphone, etc.) having a web-browser via the internet. The spreadsheet web application is configured to program the web-browser of the computing device to display and execute a spreadsheet web application having various features and functionality, including one or more of a separate design section and preview panel, a test data feature, line by line building of a spreadsheet without a starting grid of rows and columns, an embedded spreadsheet feature, an embedded worksheet display within a line feature, or any combination of these features.

Abstract: A mobile drive unit for an inventory system includes a base suspended from a frame by a pivot assembly, such as a first link and a second link. The base supports a platform configured to engage an inventory holder of the inventory system. Movement of the base causes the platform to tip, such as away from a direction of a reaction force acting on the base due to acceleration or deceleration of the mobile drive unit.

Abstract: A photonic modulator is provided that includes a transducer element that receives a RF input signal and converts the RF input signal into an elastic wave. One or more optical waveguides receive the elastic wave that has propagated a specified distance through an acoustic delay line. The one or more optical waveguides perform optomechanical transduction on the elastic wave in the presence of an optical wave, which produces one or more scattered optical waves. An optical circuit sums the one or more scattered waves to produce an optical signal output.

Abstract: The disclosure provides a cosmetic application tool including a top-face having a brush and a bottom-face having a flat and wide portion. The application tool applies skin care product onto an anatomical area to be treated, such as the face. The application tool is formed of a silicone material resistant to microbial contamination, capable of conforming to the contours of the face, and easily cleaned by rinsing with water.

Abstract: A method and apparatus 10 for interacting remotely with a vehicle 12 comprising data transfer means 22 for wirelessly communicating messages between a mobile communications device 18 operable by a user and a vehicle databus 24 located within the vehicle 12. Optionally, the data transfer means 22 is arranged to wirelessly communicate with the mobile communications device 18 via a web server 14, a web portal or other internet-connected host system. The data transfer means 22 may be arranged to wirelessly communicate with the web portal via a GSM or other cellular communications network 13. After the vehicle engine has stopped, communication of messages may continue on an intermittent basis, or may be suspended after a predetermined time has elapsed or when the vehicle battery voltage reaches a predetermined threshold. High priority messages may be communicated at any time after the vehicle engine has stopped.

Abstract: A digital printing machine includes at least one print head for inkjet printing, a drum for transporting printing material, and a spittoon for collecting ink coming from the print head. The drum has a mounting for the spittoon. The spittoon includes a support and an absorber fixed thereto. The absorber is quasi flush with the outer circumference of the drum, and the support and the absorber together form a replaceable disposable unit. A spittoon for use in a digital printing machine is also provided.

Abstract: A method for cutting thin glass, wherein the thin glass is heated with a laser beam along a path forming a cutting line moving along a forward feed direction, such that a crack propagates along the cutting line and cuts through the thin glass. The laser beam is formed by a beam-forming optic in such a way that the beam profile thereof has an elongated shape. The laser beam is orientated on the surface of the thin glass such that the longitudinal direction thereof is aligned in the feed direction. The elongated shape of the beam profile is asymmetric, such that the intensity course differs at the ends of the beam profile in such a way that the increase in intensity at the front end crossing the thin glass first is steeper than the drop in intensity at the opposite rear end.

Abstract: A gaming system includes a plurality of gaming devices and a linked game controller in data communication with the plurality of gaming devices. The linked game controller is arranged to conduct a linked game in which eligible ones of the gaming devices participate and any award is shared between the participating gaming devices. The linked game controller is arranged to conduct the linked game by generating at least one game outcome, and evaluating each game outcome to determine any award associated with the linked game to share based on the number of participating gaming devices.