Abstract: The invention relates to an ultrasonic welding device having an oscillator, having a sonotrode, which can be caused to oscillate with a wavelength, and has a welding region in the vibration antinode of the sonotrode. The sonotrode is supported at the vibration node of the sonotrode in a first bearing. To enable both a radial and an axial alignment of the sonotrode, the first bearing has a projection, which has a U-shaped geometry in a section extending in a longitudinal direction of the sonotrode, which U-shaped geometry has side legs and a cross leg that connects the side legs, the projection engages in a recess in the sonotrode matched to the U-shaped geometry, the sonotrode is supported on the cross leg of the projection in a planar manner, and the sonotrode is axially aligned by means of at least one side leg of the projection.

Abstract: The present invention provides inhibitors and/or antagonists of plasma kallikrein. Also provided are methods of utilizing the inhibitors as therapeutics.

Abstract: A piece of seating furniture has a seat plate (1) with a lower seat framework (2) arranged on the underside of said seat plate (1). Also provided is a tilting device (4), by means of which the person sitting on the piece of furniture can execute a tilting movement about a point of rotation located in the seat region. The tilting device (4) is formed by a structural unit which is separate from the seat plate (1) and is arranged on the seat plate (1) of the piece of furniture.

Abstract: Disclosed are methods for identifying high affinity adaptor molecules that bind to both a circulating antibody and a target molecule and redirect the specificity of the circulating antibody to the target molecule. Exemplary high affinity adaptor molecules are also provided.

Abstract: Methods, devices and arrays for measuring a change in zeta-potential of a surface indicative of a binding event are provided. Pharmacologically active compounds and delivery systems for active pharmaceutical ingredients determined to be pharmacologically active or optimized for pharmacological activity or determined to be useful for delivery of the active pharmaceutical ingredient to a target via measurement of a change in zeta-potential of the compound, ingredient or delivery system are also provided.

Abstract: The present invention relates to reagents and methods for purifying pertussis toxin (PT).

Abstract: The invention relates to an ultrasonic welding device having an oscillator, having a sonotrode, which can be caused to oscillate with a wavelength, and has a welding region in the vibration antinode of the sonotrode. The sonotrode is supported at the vibration node of the sonotrode in a first bearing. To enable both a radial and an axial alignment of the sonotrode, the first bearing has a projection, which has a U-shaped geometry in a section extending in a longitudinal direction of the sonotrode, which U-shaped geometry has side legs and a cross leg that connects the side legs, the projection engages in a recess in the sonotrode matched to the U-shaped geometry, the sonotrode is supported on the cross leg of the projection in a planar manner, and the sonotrode is axially aligned by means of at least one side leg of the projection.

Abstract: A method and a device are provided for producing a fiber composite component. The method includes preparing a long-fiber layer; applying short fibers to the long-fiber layer; and applying a further long-fiber layer to the long-fiber layer provided with the short fibers. The device is configured to carry out the method. The fiber composite component has a layer arrangement composed of at least two long-fiber layers, wherein the layer arrangement has an addition of short fibers. The short fibers are configured and dimensioned and are applied in such a way or are in such an arrangement that propagation of tears in one of the long-fiber layers into in each case the other or an adjacent one of the long-fiber layers and/or delamination between the long-fiber layers is rendered more difficult.

Abstract: The present invention provides inhibitors and/or antagonists of plasma kallikrein. Also provided are methods of utilizing the inhibitors as therapeutics.

Abstract: The invention relates to an ultrasound welding device for welding electrical conductors to produce a node between the conductors, comprising a compression space for receiving the conductors, which is delimited peripherally by two working surfaces delimiting the compression space on opposing sides and two lateral delimitation surfaces running transversely to the working surfaces, and the remaining sides are open. One of the working surfaces is a portion of a sonotrode, excitable in ultrasound oscillation, for the ultrasound welding device and the other working surface is a portion of a counterelectrode and at least the working surfaces are structured.

Abstract: The present invention relates to reagents and methods for purifying pertussis toxin (PT).

Abstract: A device for diagnosing an exhaust gas sensor, in particular a linear oxygen probe, for an internal combustion engine. A diagnostic unit is configured to control a first and a second current source in a coordinated manner in order to generate a first and a second current. Each of the currents has a predefined polarity sign, and is designed to determine the first and/or second and/or third voltages applied at a first and/or second and/or third terminal when first and second currents flow and put the amounts of the voltages in relation to the coordinated currents such that line interruptions and/or short circuits can be detected at the first and/or second and/or third terminal.

Abstract: The present invention provides inhibitors and/or antagonists of plasma kallikrein. Also provided are methods of utilizing the inhibitors as therapeutics.

Abstract: The invention relates to a tilting device (5) for a chair, comprising a lower plate (6) and an upper plate (7). An elastic body (8) is located therebetween. The lower plate (6) has a bulge (9) in the vertical direction, by means of which the tilting device (5) is placed onto the upper end of a gas spring (2). The seat plate (3) of the chair is fastened to the upper plate (7).

Abstract: A method and apparatus for welding lines having metallic braids or strands to form an end node or transit node by introducing a first portion of each line into a compression space of an ultrasonic welding apparatus, wherein the first portions run along a straight line, wherein at least one line has a component at a distance from the end node or transit node to be welded, and at least the line which has the component is attenuated between the compression space and the contact element in a second portion by a change in profile of the line which is imposed using a deflection device. To this end, the line which has the component is oriented in extension of the straight line.

Abstract: A screw spindle machine having a tubular casing (10) that is made of cast metal and is lined with a wear resistant layer (16), with the wear resistant layer (16) being encapsulated in a steel shell (20) that matches the outer peripheral shape of the layer (16).

Abstract: The present invention relates to reagents and methods for purifying pertussis toxin (PT).

Abstract: A method and kit for assaying a cell sample for the presence of at least a threshold number of cells of a given type are disclosed. The kit includes an assay device having a sample chamber for receiving the cell sample and an elongate collection chamber containing a selected-density and/or viscosity medium and having along its length, a plurality of cell-collection regions, and particles which are capable of specific attachment to cells of the selected cell type, and which are effective, when attached to the cells, to increase the density or magnetic susceptibility of the cells. In operation, particle-bound cells and particles in the cell sample are drawn through the elongate collection chamber under the influence of a gravitational or selected centrifugal or magnetic-field force until the particle-bound cells and particles completely fill successive cell-collection regions in the collection chamber.

Abstract: Embodiments of vehicle gesture recognition systems and methods are disclosed. An example vehicle gesture recognition system comprises a data interface configured for receiving 2d image data from a 2d sensor and/or from a portable device camera via a portable device interface. Additionally or alternatively, the data interface is configured for receiving gesture data indicating a gesture. A vehicle processing unit is configured for controlling user interfacing with a user interface based on the gestures recognized from the 2d image data and/or as indicated by the gesture data.

Abstract: Disclosed herein are devices and methods useful for the detection and analysis of various analytes. The analyte detection device of this invention has the general structure of a substrate and a plurality of pillars attached to the surface of the substrate.