Abstract: Provided herein, inter alia, are methods and compositions for treating diabetes mellitus comprising co-transplantation of an insulin-producing cell and a cell derived from a parathyroid gland (PTG), a CD34+ cell derived from a parathyroid gland, a CD34+ cell derived from a stem cell, or other progenitor cell-derived CD34+ cell.

Abstract: A belt tuning device to an accessory belt drive system (ABDS) that utilizes a torsional spring to connect the belt pulley to the shaft of a motor generator unit to isolate the system and allow the pulley to advance ahead of the motor or to be behind the motor. The tuning device also has a free running zone providing a decoupling function for the system, allowing the tuning device to be both a driver and a generator of power. The tuning device has all of the belt pulley, a spring retainer, a torsion spring, a stop ring, and a shaft fixed in relation to each other.

Abstract: A belt tuning device to an accessory belt drive system (ABDS) that utilizes a torsional spring to connect the belt pulley to the shaft of a motor generator unit to isolate the system and allow the pulley to advance ahead of the motor or to be behind the motor. The tuning device also has a free running zone providing a decoupling function for the system, allowing the tuning device to be both a driver and a generator of power. The tuning device has all of the belt pulley, a spring retainer, a torsion spring, a stop ring, and a shaft fixed in relation to each other.

Abstract: An ice-skating stride training system includes a stride pad having visual cues used for teaching ice-skating techniques and improving skating stride mechanics. The system further includes methods of use including methods for developing proper skating techniques. The system offers coaches, teams, and players a cost-effective way to increase hockey specific skating mechanics, develop better overall athletic ability, improve stride strength, and decrease risk of injury and fatigue—all without using ice.

Abstract: An isolator decoupler comprising a shaft, a pulley journalled to the shaft, a one-way clutch engaged with the shaft, a spring carrier engaged with the one-way clutch, the spring carrier having a spring carrier surface, a torsion spring having a first end laser welded to the pulley and a second end laser welded to the spring carrier, the torsion spring having a volute with a width w, an annular spring support member having a spring support member outside surface, the annular spring support member independently moveable from the spring carrier and independently moveable from the shaft, a gap g between the annular spring support member and the spring carrier, the gap g being less than the width w, the first end comprising a first end coil, the first end coil bearing upon the spring support member outside surface, the first end coil laser welded to the spring support member outside surface, a torsion spring radial contraction limited by engagement with the spring carrier surface, and the gap g and the width w hav

Abstract: Implementations for monitoring seismic data recorded in a marine survey of a subterranean formation for coverage gaps are described herein. Implementations include computing Fresnel sum operators for Fresnel zones of the subterranean formation based on a Kirchhoff migration impulse response at horizons of a representative plane layer model of a survey area of the subterranean formation. Implementations also include computing an acceptability map of the survey area based on the Fresnel sum operators. The acceptability map reveals coverage gaps in the survey area. Geoscientist may use the acceptability map to infill seismic data in areas of the survey area that correspond to the coverage gaps.

Abstract: Implementations for monitoring seismic data recorded in a marine survey of a subterranean formation for coverage gaps are described herein. Implementations include computing Fresnel sum operators for Fresnel zones of the subterranean formation based on a Kirchhoff migration impulse response at horizons of a representative plane layer model of a survey area of the subterranean formation. Implementations also include computing an acceptability map of the survey area based on the Fresnel sum operators. The acceptability map reveals coverage gaps in the survey area. Geoscientist may use the acceptability map to infill seismic data in areas of the survey area that correspond to the coverage gaps.

Abstract: An image scaling processor is disclosed comprising a multi-pixel vertical scaler and a multiline horizontal scaler. The multi-pixel vertical scaler includes a plurality of convolvers that convolve a plurality of pixels in parallel with a vertical kernel comprising weights to generate vertically scaled pixels. The multiline horizontal scaler includes horizontal scaling circuits configured to receive vertically scaled pixels from respective line stores, wherein a given horizontal scaling circuit comprises an input configured to receive one vertically scaled pixel at a time, a pipeline of convolver stages configured to, at each stage, convolve vertically scaled pixels with respective horizontal kernel coefficients. The pipeline transfers pixels from a last convolver stage of the pipeline to a second memory, wherein the pixels from the last convolver stage of the pipeline are horizontally and vertically scaled, wherein the pixels stored in the second memory are arranged to be displayed as a scaled image.

Abstract: The invention relates to a cleaning apparatus (9) for cleaning a transparent front element (11) of an optical sensor (4) for a motor vehicle (1), including the transparent front element (11) and including a light source (13) for externally illuminating the front element (11) with light beams (14), including a detector device (18) for receiving the light beams passed through the front element (11), and including an evaluation device (19), which is formed for evaluating the light beams received by the detector device (18) for determining a degree of contamination of the front element (11), wherein a control signal (22) for a cleaning device (10) of the cleaning apparatus (9) is generable depending on the evaluation such that the front element (11) is cleanable by means of the cleaning device (10). Further, the invention relates to an assembly (32) and to a method.

Abstract: The present application provides compositions and methods for treating acute lung injury and acute respiratory distress syndrome. The methods include administering one or more tight junction antagonists to the lung of a subject in need thereof.

Abstract: We describe a method for reducing bow in a composite wafer comprising a silicon wafer and a silicon carbide layer grown on the silicon wafer. The method includes applying nitrogen atoms during the growth process of the silicon carbide layer on the silicon wafer so as to generate a compressive stress within the composite wafer.

Abstract: An isolator comprising a shaft, a pulley journalled to the shaft, a first torsion spring engaged between the shaft and the pulley, a second torsion spring engaged between the shaft and the pulley, the first torsion spring and the second torsion spring wound in opposite directions, the first torsion spring engaged to transmit a first torque in a first direction from the pulley to the shaft, the second torsion spring having a passive engagement with the pulley during transmission of the first torque, and the second torsion spring engaged to transmit a second torque in a second direction from the shaft to the pulley, the first torsion spring having a passive engagement with the pulley during transmission of the second torque.

Abstract: Silicon photomultiplier circuitry is provided that comprises at least one silicon photomultiplier pixel, each pixel comprising a plurality of silicon photomultiplier microcells. The silicon photomultiplier circuitry comprises control circuitry adapted to maintain a substantially constant voltage on a connection node between microcells of the pixel. The control circuitry is adapted to minimise the onset and recovery time of an output signal by maintaining a substantially constant voltage on the connection node.

Abstract: A board game that simulates basketball, including a board, a plurality of markers, a pair of dice and a defense die. The board includes a top playing surface, which includes two halves, a centerline and a plurality of marker player positions. The plurality of marker player positions include benching, initiating, and shooting positions. Each shooting position is associated with a specific roll of two dice that must be met to score. Players are represented by markers, and on each turn, each player can make three moves, each move represent by moving one space on the board. On the third move, a player may opt to take a shot on basket by rolling the dice to try to match a qualifying roll total for the shooting position. If a qualifying roll total is met, then the marker player scores by removing the marker player from the board.

Abstract: The invention relates to a method for providing at least one information from an environmental region (8) of a motor vehicle (2) to a driver of the motor vehicle (2), wherein at least one first image (B3) captured by a vehicle-side camera system (6) and at least one second image (B4) captured by a vehicle-external camera system (7) situated within the field of view (19a, 19b) of the vehicle-side camera system (6) are received in the method, wherein an image-in-image representation (B5) is generated from the at least one first image (B3) and the at least one second image (B4) for displaying on a vehicle-side display device (13) as the at least one information, wherein a first image region (21) for displaying the at least one first image (B3) and a second image region (22) separate from the first image region (21) for displaying the at least one second image (B4) are determined for the image-in-image representation (B5).

Abstract: An isolator decoupler comprising a shaft, a pulley journalled to the shaft, a one-way clutch engaged with the shaft, a spring carrier engaged with the one-way clutch, the spring carrier having a spring carrier surface, a torsion spring having a first end laser welded to the pulley and a second end laser welded to the spring carrier, the torsion spring having a volute with a width w, an annular spring support member having a spring support member outside surface, the annular spring support member independently moveable from the spring carrier and independently moveable from the shaft, a gap g between the annular spring support member and the spring carrier, the gap g being less than the width w, the first end comprising a first end coil, the first end coil bearing upon the spring support member outside surface, the first end coil laser welded to the spring support member outside surface, a torsion spring radial contraction limited by engagement with the spring carrier surface, and the gap g and the width w hav

Abstract: We disclose a high voltage semiconductor device comprising a semiconductor substrate of a second conductivity type; a semiconductor drift region of the second conductivity type disposed over the semiconductor substrate, the semiconductor substrate region having higher doping concentration than the drift region; a semiconductor region of a first conductivity type, opposite to the second conductivity type, formed on the surface of the device and within the semiconductor drift region, the semiconductor region having higher doping concentration than the drift region; and a lateral extension of the first conductivity type extending laterally from the semiconductor region into the drift region, the lateral extension being spaced from a surface of the device.

Abstract: The invention relates to a method for providing at least one information from an environmental region (8) of a motor vehicle (2) to a driver of the motor vehicle (2), wherein at least one first image (B3) captured by a vehicle-side camera system (6) and at least one second image (B4) captured by a vehicle-external camera system (7) situated within the field of view (19a, 19b) of the vehicle-side camera system (6) are received in the method, wherein an image-in-image representation (B5) is generated from the at least one first image (B3) and the at least one second image (B4) for displaying on a vehicle-side display device (13) as the at least one information, wherein a first image region (21) for displaying the at least one first image (B3) and a second image region (22) separate from the first image region (21) for displaying the at least one second image (B4) are determined for the image-in-image representation (B5).

Abstract: Silicon photomultiplier circuitry is provided that comprises at least one silicon photomultiplier pixel, each pixel comprising a plurality of silicon photomultiplier microcells. The silicon photomultiplier circuitry comprises control circuitry adapted to maintain a substantially constant voltage on a connection node between microcells of the pixel. The control circuitry is adapted to minimise the onset and recovery time of an output signal by maintaining a substantially constant voltage on the connection node.

Abstract: The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain 3,3-disubstituted-(8-aza-bicyclo[3.2.1]oct-8-yl)-[5-(1H-pyrazol-4-yl)-thiophen-3-yl]-methanone, 3,3-disubstituted-(6-aza-bicyclo[3.1.1]hept-6-yl)-[5-(1H-pyrazol-4-yl)-thiophen-3-yl]-methanone, and 4,4-disubstituted piperidin-1-yl)-[5-(1H-pyrazol-4-yl)-thiophen-3-yl]-methanone compounds of the following formula that, inter alia, inhibit 11?-hydroxysteroid dehydrogenase type 1 (11?-HSD1).