Abstract: Disclosed are novel methods of using elongation factor p (efp) and related constituents of ribosomal complexes which comprise efp, the 50S ribosomal subunit, the 30S ribosomal subunit, the 70S initiation complex, and related proteins, cofactors and enzymes. Methods of identifying compounds which modulate prokaryotic elongation factor p and modify cell function are described. Both in vitro and in vivo methods for identifying compounds which modulate such constituents and affect cell function are described. Such identified compounds, including various antibiotics, which specifically affect cell growth, methods of treating various disorders with such compounds, and antiseptics containing such compounds are described. The present invention is also directed to methods and compounds that modulate prokaryotic elongation factor p.

Abstract: A cable tie includes a head having an elongate passage therethrough and a strap insertable into the head. The head includes a metallic barb supported therein which extends into the passage for locking engagement with the strap. The barb includes a portion embedded into the head and a portion extending therefrom. A cable tie exhibiting high withdrawal or pull-out strength with low strap insertion force is obtained by significantly increasing the length of the unembedded portion of the barb with respect to both the embedded portion and the thickness of the strap.

Abstract: A printed circuit board guide rail has one or more detents projecting far enough into the area traversed by the board to apply a horizontal holding and an antivibration pressure thereto. A notch window is formed in the part of the rail under the detent to give it a fixed-fixed suspended leaf spring quality for minimumizing vibration. The unnotched remainder of the rail enables a printed circuit board to slide freely thereover. The rail is arched to give vertical stability.