Abstract: Provided is a system and method for determining an appropriate dosage of a product. The method includes, receiving from a User a User Request for a Dosage, the User Request including at least a User Reason and a User Location; accessing a Database of Products, each Product having at least one Constituent, at least one Established Reason, a Dosage for each Established Reason, and Provider Location; querying the Database of Products with the User Request to determine at least a first subset of Products having the at least one Established Reason correlating to the User Reason; and providing the User with the first subset of Products arranged by proximity of the Provider Location to the User Location, the first subset of Products further including the Dosage for each Product in the first subset of Products. An associated system is also provided.

Abstract: Disclosed are systems and methods that automatically classify, segment, and parse content data using artificial intelligence and natural language processing technology, and generate graphical user interfaces that allow end users to dynamically filter content data for display. The systems processes volumes of content data to identify interrogative data, content sources that generated the interrogative data, and subject identifiers relating to the content data. The system generates graphical user interfaces that allow end users to effectively filter the data by choosing between layouts that display one or more of the various categories of data, including the interrogative data, content source identifiers, and/or subject identifiers.

Abstract: A dental cleaning appliance includes a handle, a fluid reservoir for storing a working fluid, and a fluid delivery system for receiving working fluid from the reservoir, and for delivering working fluid to the oral cavity of a user. The fluid reservoir includes a fluid port from which fluid is dispensed from the fluid reservoir, and through which the fluid reservoir is replenished. The fluid reservoir is moveable along the handle between a first position in which the fluid port is connected to the fluid delivery system, and a second position in which the fluid port is exposed to allow the fluid reservoir to be replenished.

Abstract: Various embodiments include methods and devices for implementing a criterion aware cache replacement policy by a computing device. Embodiments may include updating a staling counter, writing a value of a local counter to a system cache in association with a location in the system cache for with data, in which the value of the local counter includes a value of the staling counter when (i.e., at the time) the associated data is written to the system cache, and using the value of the local counter of the associated data to determine whether the associated data is stale.

Abstract: A tube seal device suitable for use in a heat exchange reactor comprising one or more tubes is described, said tube seal device comprising a seal tube and an inner tube disposed within the seal tube to provide an overlapping region, said inner tube having within said overlapping region, (i) an interior constriction of reduced cross sectional area forming a low-pressure region, (ii) an expansion region adjacent the constriction of cross sectional area greater than that of the constriction, and (iii) one or more passages through the wall of the inner tube connecting said low-pressure region to the exterior of the inner tube, wherein the tube seal device further comprises one or more grooves formed around an inner face of the seal tube in the overlapping region corresponding to the low-pressure region of the inner tube.

Abstract: An article of footwear includes an upper defining an interior void and a first cable movable in a tightening direction to move the upper into a tightened state and movable in a loosening direction to move the upper into a loosened state. The article of footwear also includes a tightening grip operable to be moved away from the upper in a first direction to move the first cable in the tightening direction and a cable lock operable in a locked state to restrict movement of the first cable in the loosening direction and operable in an unlocked state to permit movement of the first cable in the loosening direction. A release grip is operable to be moved away from the upper in a second direction to move the cable lock from the locked state to the unlocked state, whereby the release grip is separate from the tightening grip.

Abstract: Provided are anti-CD8 antibodies that bind human CD8 and do not stimulate or inhibit the activation of CD8+ T cells. Also provided are nucleic acids encoding such anti-CD8 antibodies, vectors comprising such nucleic acids, host cells comprising same, and methods of making such anti-CD8 antibodies. Also provided are anti-CD8 antibodies conjugated to a detectable label. Provided are methods of using such anti-CD8 antibodies to detect CD8+ T cells in a subject, monitor disease progress in a subject having cancer, and monitor treatment progress in a subject having cancer.

Abstract: Compositions for prevention of Foot and Mouth Disease (FMD) are provided, comprising an antigen component in the amount equivalent to 0.5-20 ?g FMD virus and an adjuvant component comprising oil, an immunostimulatory oligonucleotide, and a polycationic carrier. Methods of using the composition, as well as the methods of reducing FMD persistence are also provided.

Abstract: Examples of methods are described. In some examples, a method includes sending a video feed from a client device to a host device. In some examples, the method includes receiving a stream from the host device. In some examples, the stream includes a region based on the video feed. In some examples, the method includes replacing the region with the video feed.

Abstract: A system, apparatus, and method to monitor an event associated with a person and report the event as a tokens to other devices or to a central server.

Abstract: A system, apparatus, and method to monitor an event associated with a person and report the event as a tokens to other devices or to a central server.

Abstract: Systems and apparatus related to adaptive support garments including adaptive support structures, lacing systems, and an adaptive engine are discussed. In an example, an adaptive support garment can include a textile-based support structure, an adaptive support structure and an adaptive engine is described. The textile-based support structure is configured to support a portion of anatomy of a wearer. The adaptive support structure is integrated into the textile-based support structure and configured to adjust a portion of the textile-based support structure. The adaptive engine is coupled to the adaptive support structure to activate adjustment of the portion of the textile-based support structure.

Abstract: In some examples, an electronic device includes a processor to determine a threshold magnitude. Based on the threshold magnitude, the processor is to determine a bit mapping for a partial timestamp. The partial timestamp is a sequence of bits of a timestamp that is based on a clock signal of the processor. The processor is to determine the partial timestamp based on the bit mapping and the timestamp, append the partial timestamp to a data signal, and cause transmission of the data signal.

Abstract: The disclosure provides a dosing regimen utilizing an oral extended release formulation for the treatment of treatment-resistant depression and treatment-resistant anxiety.

Abstract: This specification describes a simulation system that performs simulations of physical environments using a graph neural network. At each of one or more time steps in a sequence of time steps, the system can process a representation of a current state of the physical environment at the current time step using the graph neural network to generate a prediction of a next state of the physical environment at the next time step. Some implementations of the system are adapted for hardware GLOBAL acceleration. As well as performing simulations, the system can be used to predict physical quantities based on measured real-world data. Implementations of the system are differentiable and can also be used for design optimization, and for optimal control tasks.

Abstract: The disclosure relates to medical devices and methods of manufacturing medical devices. An orthopedic screw includes a shaft having a proximal end, a distal end, a body extending between the proximal end and the distal end, and a longitudinal axis. A distal thread on an external surface of the shaft extends around the longitudinal axis. A head portion includes a series of cutting teeth that lie on a plane that is perpendicular to the longitudinal axis of the shaft. A distal tip portion defines a cutting edge.

Abstract: A system, apparatus, and method to monitor at least one person in at least one environment. A care processing system receives data from at least one sensor in an environment for a monitoring a person under care. The data received is matched to a pattern for such data configured by the signal processing system. Upon the matching of such data, at least a first sensor creates an event that in whole or in part matches such pattern. The signal processing configures a first sensor to collect data created by such event, or instructs a second and subsequent set of sensors to collect data about the event, such that signal processing may determine the accuracy of such data for matching of the pattern. The situation is represented for a monitored person in an environment for the purpose of providing care to that person.

Abstract: A system, apparatus, and method to monitor at least one person in at least one environment. The environment includes at least two sensors capable of detecting the presence of a person in that environment. The person under monitoring has a care condition to be monitored, where such monitoring involves the at least two sensors providing data sets to at least one signal monitoring system. Such data sets are communicated to at least one digital twin representing the person under monitoring and their environment, such that patterns of behavior may be determined for that person. Such patterns may be represented in the at least one digital twin, as to detect behavior that indicates a change in the care condition of that person under monitoring.

Abstract: A bottle assembly has a bottle and a removable cap. The cap includes a nozzle and a vent arrangement. The vent arrangement can include a vent conduit that extends into an air cavity present at the bottom of the bottle assembly when the bottle assembly is inverted. The vent arrangement allows for pressure equalization within the bottom assembly in response to liquid being dispensed from the bottle assembly to permit high flow rates of the dispensed liquid without squeezing of the bottle.

Abstract: A multi-functional slurry processing system (“VARCOR”) and associated methods is disclosed. The present examples provide a multi-functional slurry processing system incorporating systems and methods for separating liquid and solid components in slurries. In particular the systems and methods described herein produce clean water, dried solids, and potential concentration of desirable constituents with a boiling point lower than water. At least one example of the multi-functional slurry processing system provides a self-contained processing facility configured to efficiently convert high water-content slurries into its constituent solid and liquid fractions and subsequently generating and collecting clean water and concentrating desirable constituents with a boiling point lower than water.