Abstract: A method of treating HIV comprising intramuscular administration once every 4 weeks or less frequently of a combination of cabotegravir or a pharmaceutically acceptable salt thereof and rilpivirine or a pharmaceutically acceptable salt thereof, including the option of discontinuing administration of a first oral anti-retroviral regimen and intramuscularly administering, once four weeks or less often said combination of cabotegravir and rilpivirine.

Abstract: A method for producing conductive materials from Nb-doped TiO2-particles, in which Nb-doped TiO2-particles are pressed to form bodies and the bodies are treated in an oxygen-containing atmosphere and at a reducing atmosphere.

Abstract: In a dosage system for delivering a predetermined amount and type of cleaning concentrate to a solvent inside a fluid tank, a pod holder is configured to form an inner volume for holding a pod containing the cleaning concentrate. A connector is configured to form a fluid connection between the inner volume of the pod holder and the inside of the fluid tank. A piercing device is configured to pierce the pod held by the pod holder. A push mechanism is configured to push the piercing device into the inner volume of the pod holder for piercing the pod to release the cleaning concentrate from the pod via the fluid connection of the connector into the inside of the fluid tank.

Abstract: A wafer test device includes a test interconnect to interface with a microcircuit of the wafer at a first side and an interposer to interface with the test interconnect at a second side of the test interconnect, opposite the first side. The interposer connects the test interconnect, via a printed circuit board (PCB), to a test apparatus that determines and controls test patterns that are applied to the microcircuit via the test interconnect. A support structure supports the test interconnect and the interposer. The support structure includes an inner bearing to tilt the test interconnect to match a tilt of a surface of the microcircuit. An elastomer between the test interconnect and the interposer reduces deflection of the test interconnect during a process of connecting the test interconnect to the microcircuit.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for generating data specifying a three-dimensional mesh of an object using an auto-regressive neural network.

Abstract: A computer-implemented method, in which an access request in relation to data is received. There is Error Correcting Code (ECC) data relating to the data, and the ECC data is configured to enable correction of multiple-bit errors spanning up to a predetermined number of consecutive bits of the data. The ECC data is configured to enable correction of multiple-bit errors spanning up to a predetermined number of consecutive bits of the data. A first integrity verification verifies the integrity of at least the data. If the first integrity verification procedure fails, an error analysis procedure is performed based on the data and the ECC data. Responsive to generation of corrected data by the error analysis procedure, a second integrity verification verifies the integrity of the corrected data. If the second integrity verification is successful, the access request is allowed using the corrected data.

Abstract: Examples of methods are described. In some examples, a method includes evaluating, by an electronic device, resource state information based on a policy. In some examples, the method includes determining, by the electronic device, to change from a second encoder to a first encoder based on the evaluation. In some examples, the first encoder is to encode a desktop display image sequence. In some examples, the method includes communicating, by the electronic device, the encoded desktop display image sequence.

Abstract: A method of treating HIV comprising intramuscular administration once every 4 weeks or less frequently of a combination of cabotegravir or a pharmaceutically acceptable salt thereof and rilpivirine or a pharmaceutically acceptable salt thereof, including the option of discontinuing administration of a first oral anti-retroviral regimen and intramuscularly administering, once four weeks or less often said combination of cabotegravir and rilpivirine.

Abstract: The present disclosure relates generally to culture media formulations and culture methods. More particularly, the present disclosure provides defined serum-free culture media, kits and methods for generating progenitor T cells and derivatives thereof, including mature T cells. The present disclosure further provides the cells generated using the media, kits and methods, as well as methods of treatment using the generated cells.

Abstract: A method may include receiving a consent-processing request at a consent management platform from a content-presentation device, and using an identifier string in the request to establish a secure interactive session configured for user selection of consent options associated with a particular consent package of the platform, where the package may include identifiers of consent features of a media distribution system that require user consent in order to be activated for the device. The platform may then receive, via the interactive session, user consent data including a respective consent choice for each of one or more consent options, where each respective consent choice indicates acceptance or rejection of consent to activating an associated consent feature identified with the particular consent package. The received respective consent choices may be stored in a database of the consent management platform. Corresponding data may be stored in a whitelist on the content-presentation device.

Abstract: In one aspect, a drug delivery device is provided for delivering drug from a plurality of drug cartridges. The drug delivery device includes: a cylindrical cassette configured to accommodate the plurality of drug cartridges; a reversibly advanceable plunger; and, an indexer for incrementally rotating the cassette to align the plurality of drug cartridges individually with the plunger. The indexer includes first and second shafts with cooperating elements which cause incremental rotation of the first shaft, relative to the second shaft, upon the second shaft engaging the first shaft.

Abstract: The disclosure provides an oral extended release formulation for the treatment of treatment-resistant depression and treatment-resistant anxiety.

Abstract: A top drive for well operations having a gearbox, a traction motor connected to the gearbox so that a motor shaft of the traction motor extends into the gearbox, a quill extending into the gearbox, a gear train positioned within the gearbox and mechanically connected between the traction motor shaft and the quill, and a connector positioned in the gear train, wherein in a coupled configuration the connector communicates torque through the gear train, and wherein in a decoupled configuration the connector does not communicate torque through the gear train. A method for operating a top drive by applying a first torque to a quill with two traction motors, disconnecting one of the traction motors from the quill, and applying a second torque less than the first torque to the quill with the non-disconnected traction motor.

Abstract: A method for forming a composite fluid conduit includes providing an inner pipe having a variation in cross-section between at least two different longitudinal sections thereof and applying a fiber reinforced composite material to the inner pipe. In some disclosed examples the variation in cross section may be provided intermediate opposing ends of the inner pipe. In other disclosed examples the variation in cross section may be provided at an end region of the inner pipe.

Abstract: A reinforcement learning system and method that selects actions to be performed by an agent interacting with an environment. The system uses a combination of reinforcement learning and a look ahead search: Reinforcement learning Q-values are used to guide the look ahead search and the search is used in turn to improve the Q-values. The system learns from a combination of real experience and simulated, model-based experience.

Abstract: A method for the production of conductive structures, wherein nanofibers are applied with a photocatalytic component onto a substrate, in particular by electrospinning, and wherein a metallic layer is deposited photolytically on the substrate.

Abstract: The invention provides an oral extended release formulation for the treatment of treatment-resistant depression, treatment-resistant anxiety, and phobia.

Abstract: A solenoid comprises first and second coils connected to an electrical power supply circuit. In a first mode of operation the power supply circuit is arranged to provide a current flowing in opposite directions through the respective first and second coils, e.g. to produce a self-heating effect. In a second mode of operation the power supply circuit is arranged to provide a current flowing in the same direction through the respective first and second coils, e.g. to generate a magnetic force. In some embodiments, the power supply circuit includes a bridge rectifier or full wave rectifier connected to a bi-directional current driver.

Abstract: An article of footwear includes an upper defining an interior void and a first cable movable in a tightening direction to move the upper into a tightened state and movable in a loosening direction to move the upper into a loosened state. The article of footwear also includes a tightening grip operable to be moved away from the upper in a first direction to move the first cable in the tightening direction and a cable lock operable in a locked state to restrict movement of the first cable in the loosening direction and operable in an unlocked state to permit movement of the first cable in the loosening direction. A release grip is operable to be moved away from the upper in a second direction to move the cable lock from the locked state to the unlocked state, whereby the release grip is separate from the tightening grip.

Abstract: The invention provides an oral extended release formulation for the treatment of treatment-resistant depression, treatment-resistant anxiety, and phobia.