Patents by Inventor Philip James Stephens

Philip James Stephens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • KIF5B-RET fusion molecules and uses thereof
    Patent number: 9297011
    Abstract: Novel RET fusion molecules and uses are disclosed.
    Type: Grant
    Filed: February 23, 2014
    Date of Patent: March 29, 2016
    Assignee: FOUNDATION MEDICINE, INC.
    Inventors: Sean R. Downing, Matthew J. Hawryluk, Doron Lipson, Alexander N. Parker, Philip James Stephens
  • METHODS OF TREATING CHOLANGIOCARCINOMA
    Publication number: 20150366866
    Abstract: Methods and compositions for treating cholangiocarcinoma.
    Type: Application
    Filed: January 17, 2014
    Publication date: December 24, 2015
    Inventors: Siraj Mahamed Ali, Matthew J. Hawryluk, Jie He, Doron Lipson, Vincent A. Miller, Jeffrey S. Ross, Philip James Stephens
  • NOVEL NTRK1 FUSION MOLECULES AND USES THEREOF
    Publication number: 20150073036
    Abstract: Novel NTRK1 fusion molecules, detection reagents, and uses and kits for evaluating, identifying, assessing and/or treating a subject having a cancer are disclosed.
    Type: Application
    Filed: August 29, 2014
    Publication date: March 12, 2015
    Inventors: Matthew J. Hawryluk, Doron Lipson, Vincent A. Miller, Philip James Stephens
  • SYSTEM AND METHOD FOR MANAGING GENOMIC INFORMATION
    Publication number: 20150046191
    Abstract: Various embodiments provide interfaces to access genomic testing information and incorporate it into daily physician practice. According to one aspect, a graph-based data model is used that may be used to organizes and revise precision medicine knowledge. In one example structure, gene states are abstracted into alteration groups, where alteration groups are built using reverse engineering actionable information and storing that information within the graph-based data structure. Volumes of genomic alterations and associated information (e.g., journal articles, clinical trial information, therapies, etc.) are analyzed and synthesized into actionable information items viewable on an alteration system in a graph-based data format. According to one embodiment, the system can be configured to focus practitioners on discrete portions of the alteration information on which they can act.
    Type: Application
    Filed: August 19, 2014
    Publication date: February 12, 2015
    Inventors: Helena Futscher de Deus, Rachel Lauren Erlich, Ronald David Collette, Alexander N. Parker, Michael Pellini, Gary Palmer, Mary Pat Lancelotta, Matthew J. Hawryluk, Philip James Stephens, Eric Karl Neumann, Jeffrey B. Collemer
  • SYSTEM AND METHOD FOR MANAGING GENOMIC INFORMATION
    Publication number: 20150046180
    Abstract: Various embodiments provide interfaces to access genomic testing information and incorporate it into daily physician practice. According to one aspect, a graph-based data model is used that may be used to organizes and revise precision medicine knowledge. In one example structure, gene states are abstracted into alteration groups, where alteration groups are built using reverse engineering actionable information and storing that information within the graph-based data structure. Volumes of genomic alterations and associated information (e.g., journal articles, clinical trial information, therapies, etc.) are analyzed and synthesized into actionable information items viewable on an alteration system in a graph-based data format. According to one embodiment, the system can be configured to focus practitioners on discrete portions of the alteration information on which they can act.
    Type: Application
    Filed: August 19, 2014
    Publication date: February 12, 2015
    Inventors: Helena Futscher de Deus, Rachel Lauren Erlich, Ronald David Collette, Alexander N. Parker, Michael Pellini, Gary Palmer, Mary Pat Lancelotta, Matthew J. Hawryluk, Philip James Stephens, Eric Karl Neumann
  • HUMAN PAPILLOMA VIRUS AS PREDICTOR OF CANCER PROGNOSIS
    Publication number: 20150030587
    Abstract: Methods of treating a head and neck cancer are disclosed.
    Type: Application
    Filed: February 11, 2014
    Publication date: January 29, 2015
    Applicant: FOUNDATION MEDICINE, INC.
    Inventors: Chris Hendrik Boshoff, Timothy Robert Fenton, Matthias Alexander Lechner, Philip James Stephens, Matthew J. Hawryluk, Garrett Michael Frampton, Roman Yelensky
  • METHODS OF TREATING UROTHELIAL CARCINOMA
    Publication number: 20150023965
    Abstract: Methods and compositions for treating a urothelial and/or a micropapillary carcinoma, such as a micropapillary urothelial carcinoma are disclosed.
    Type: Application
    Filed: July 16, 2014
    Publication date: January 22, 2015
    Applicant: FOUNDATION MEDICINE, INC.
    Inventors: Siraj Mahamed Ali, Matthew J. Hawryluk, Jeffrey S. Ross, Philip James Stephens
  • NOVEL KIF5B-RET FUSION MOLECULES AND USES THEREOF
    Publication number: 20140243390
    Abstract: Novel RET fusion molecules and uses are disclosed.
    Type: Application
    Filed: February 23, 2014
    Publication date: August 28, 2014
    Applicant: FOUNDATION MEDICINE, INC.
    Inventors: Sean R. Downing, Matthew J. Hawryluk, Doron Lipson, Alexander N. Parker, Philip James Stephens
  • NOVEL ESTROGEN RECEPTOR MUTATIONS AND USES THEREOF
    Publication number: 20140221329
    Abstract: Novel mutant ESR1 molecules and uses are disclosed.
    Type: Application
    Filed: April 14, 2014
    Publication date: August 7, 2014
    Applicant: FOUNDATION MEDICINE, INC.
    Inventors: Maureen T. Cronin, Garrett Michael Frampton, Doron Lipson, Vincent A. Miller, Gary Palmer, Jeffrey S. Ross, Philip James Stephens, Roman Yelensky
  • Human papilloma virus as predictor of cancer prognosis
    Patent number: 8673972
    Abstract: Methods of treating a head and neck cancer are disclosed.
    Type: Grant
    Filed: August 2, 2013
    Date of Patent: March 18, 2014
    Assignees: Foundation Medicine, Inc., UCL Business PLC
    Inventors: Chris Hendrik Boshoff, Timothy Robert Fenton, Matthias Alexander Lechner, Philip James Stephens, Matthew J. Hawryluk, Roman Yelensky, Garrett Michael Frampton
  • HUMAN PAPILLOMA VIRUS AS PREDICTOR OF CANCER PROGNOSIS
    Publication number: 20140037622
    Abstract: Methods of treating a head and neck cancer are disclosed.
    Type: Application
    Filed: August 2, 2013
    Publication date: February 6, 2014
    Applicants: UCL BUSINESS PLC, FOUNDATION MEDICINE, INC.
    Inventors: Chris Hendrik Boshoff, Timothy Robert Fenton, Matthias Alexander Lechner, Philip James Stephens, Matthew J. Hawryluk, Roman Yelensky, Garrett Michael Frampton
  • OPTIMIZATION OF MULTIGENE ANALYSIS OF TUMOR SAMPLES
    Publication number: 20120208706
    Abstract: A method of analyzing a tumor sample comprising: (a) acquiring a library comprising a plurality of tumor members from a tumor sample; (b) contacting the library with a bait set to provide selected members; (c) acquiring a read for a subgenomic interval from a tumor member from said library; (d) aligning said read; and (e) assigning a nucleotide value (e.g., calling a mutation) from said read for the preselected nucleotide position, thereby analyzing said tumor sample.
    Type: Application
    Filed: December 29, 2011
    Publication date: August 16, 2012
    Applicant: FOUNDATION MEDICINE, INC.
    Inventors: Sean R. Downing, Mirna Jarosz, Doron Lipson, Geoffrey Alan Otto, Alexander N. Parker, Mikhail G. Shapiro, Philip James Stephens, Roman Yelensky