Abstract: A belt assembly is provided for use as an endless belt traveling relative to a frame structure. The belt assembly comprises a first fabric layer and a second fabric layer having an outer surface that at least partially forms a bottom surface of the belt. A composition comprising polyvinyl chloride is adhered to the inner surface of the first fabric layer. A composition comprising polyurethane is adhered to the inner surface of the second fabric layer. A coating composition comprising polyvinyl chloride is disposed between the inner surfaces of the first fabric layer and the second fabric layer for joining the first fabric layer and the second fabric layer. An at least substantially solid lubricant composition is impregnated in the second fabric layer and at least partially forms the bottom surface of the belt.

Abstract: An endless treadmill belt includes a bottom-ply fabric that at least partially forms a bottom surface of the belt, and the bottom surface of the belt is for sliding across a treadmill deck. The bottom-ply fabric includes textured synthetic yarns that at least partially form the bottom surface of the belt. A solid lubricant composition is impregnated in the bottom-ply fabric. The solid lubricant composition is a mixture that includes higher and lower viscosity lubricants and a binder.

Abstract: The present invention is transgenic chickens obtained from long-term cultures of avian PGCs and techniques to produce and transgenic birds derived from prolonged PGC cultures. In some embodiments, these PGCs can be transfected with genetic constructs to modify the DNA of the PGC, specifically to introduce a transgene encoding an exogenous protein. When combined with a host avian embryo by known procedures, those modified PGCs are transmitted through the germline to yield transgenic offspring. This invention includes compositions comprising long-term cultures of PGCs that can be genetically modified by gene targeting, that can accept large amounts of foreign DNA and that contribute to the germline of recipient embryos.

Abstract: The present invention is long-term cultures of avian PGCs and techniques to produce germline chimeric and transgenic birds derived from prolonged PGC cultures. In some embodiments, these PGCs can be transfected with genetic constructs to modify the DNA of the PGC, specifically to introduce a transgene encoding an exogenous protein. When combined with a host avian embryo by known procedures, those modified PGCs produce germline chimeric birds. These germline chimeric birds do not have PGC derived somatic cells or tissues. This invention includes compositions comprising long-term cultures of PGCs that can be genetically modified by gene targeting, that can accept large amounts of foreign DNA and that contribute to the germline of recipient embryos.

Abstract: The present invention is long-term cultures of avian PGCs and techniques to produce germline chimeric and transgenic birds derived from prolonged PGC cultures. In some embodiments, these PGCs can be transfected with genetic constructs to modify the DNA of the PGC, specifically to introduce a transgene encoding an exogenous protein. When combined with a host avian embryo by known procedures, those modified PGCs are transmitted through the germline to yield transgenic offspring. These germline chimeric birds do not have substantial contributions of PGC-derived phenotypes in somatic cells or tissues. This invention includes compositions comprising long-term cultures of PGCs that can be genetically modified by gene targeting, that can accept large amounts of foreign DNA and that contribute to the germline of recipient embryos.

Abstract: A composite sheet includes a fabric that is at least partially embedded in a polymeric sheet. The fabric includes longitudinally extending warp yarns and laterally extending weft yarns, with there being one or more pairs of substantially spaced apart, yet adjacent, warp yarns. For each pair, the two warp yarns are sufficiently spaced apart from one another so that the composite sheet can be longitudinally slit between and distant from the two warp yarns, to provide one or more sections of the composite sheet that can be used as conveyor belts. The warp yarns are not exposed at the cut edges.

Abstract: Human antibodies are produced in transgenic chickens having functional genetic components of the human immune system stably integrated in the genome. Techniques are described to integrate unrearranged human heavy and light chain immunoglobulin loci into the genome of the transgenic chicken. The functional description of the endogenous immunoglobulin loci yields an animal whose antibody repertoire in response to antigen is fully human. In the preferred embodiment, the human immunoglobulin locus is at least as large as the native human locus and exhibits functional class switching to yield IgG isotype antibodies. In addition to monoclonal antibodies secreted from immortalized B cell populations, polyclonal antibodies may be obtained from eggs laid by the transgenic chickens of the invention.

Abstract: A composite sheet includes a fabric that is at least partially embedded in a polymeric sheet. The fabric includes longitudinally extending warp yarns and laterally extending weft yarns, with there being one or more pairs of substantially spaced apart, yet adjacent, warp yarns. For each pair, the two warp yarns are sufficiently spaced apart from one another so that the composite sheet can be longitudinally slit between and distant from the two warp yarns, to provide one or more sections of the composite sheet that can be used as conveyor belts. The warp yarns are not exposed at the cut edges.

Abstract: An endless treadmill belt includes a bottom-ply fabric that at least partially forms a bottom surface of the belt, and the bottom surface of the belt is for sliding across a treadmill deck. The bottom-ply fabric includes textured synthetic yarns that at least partially form the bottom surface of the belt. A solid lubricant composition is impregnated in the bottom-ply fabric. The solid lubricant composition is a mixture that includes higher and lower viscosity lubricants and a binder.

Abstract: An endless treadmill includes a bottom-ply fabric that at least partially forms a bottom surface of the belt that is for sliding across a treadmill deck. The bottom-ply fabric has warp yarns that at least partially form the bottom surface of the belt, with a large number of these warp yarns, and preferably all of these warp yarns, being less than about 1000 denier, or more preferably about 500 denier or smaller. In addition, the warp yarns that at least partially form the bottom surface of the belt are twisted about 2.5 complete turns per inch, or less. A solid lubricant composition is preferably impregnated in the bottom-ply fabric. The solid lubricant composition includes a wax mixture and it optionally further includes a lower viscosity lubricant, such as silicone. The wax mixture may include a vegetable wax and a mineral wax, such as a mixture of paraffin wax and carnauba wax.

Abstract: The invention provides methods and compositions for expressing targeted gene products in vertebrate neurons. The compositions include gene trap vectors comprising a polynucleotide comprising promoterless selectable marker and axon reporter encoding sequences, which may be operatively joined to an internal ribosome-entry site, and may comprise a splice acceptor site located 5′ to the selectable marker and axon reporter encoding sequences. The methods include methods of expressing an axon reporter in a cell by transferring the subject vectors into an embryonic stem cell and incubating the cell under conditions whereby the cell or a progeny of the cell differentiates into a neuron comprising an axon or dendrites, and the neuron expresses the axon reporter under the transcriptional control of the gene; and specifically detecting the axon reporter in the axon or dendrites. Neuronal specific expression may also be effected in disclosed binary systems.

Abstract: A multichannel radiotelephony system provides two way cordless communications with a plurality of multichannel transceivers portable within a coverage area comprised by a plurality of cells, each associated with a base station and antennas, such as to permit channel frequency reuse in cells within the coverage area. For at least part of the coverage area, the locations of the antennas within the cells and the locations of the base stations are independently mapped, the antennas being associated with active antenna systems and the active antenna systems being connected to the base stations utilizing broadband transmission by means of a fixed bi-directional signal distribution network. The network is connected to the base stations and the antenna systems through suitable interfaces incorporating frequency translation so that available frequency bands in the signal distribution network which will normally be shared with other services, may be utilised. Plural base stations may be co-located.