Abstract: The invention provides compounds of formula (I): wherein E, A, B?, R6, R7, R8, and R9 are defined in the specification which compounds exhibit anticancer activity and are useful for treating cancer.

Abstract: The present invention discloses a method and system for developing and operating interactive Web applications in a unified, light-weight, on-demand, modular server application framework. The present invention provides a novel unified approach utilizing a single programming language to develop interactive Web applications. The modular Web applications of the present invention operate at the server-side. The Web application of the present invention comprises one or more Web application modules written entirely in a scripting programming language. The Web application modules are interpreted and executed by the scripting language interpreter engine to generate all of the code necessary, such as the HTML and JavaScript code, to service the requests from the clients. Unlike existing server-based integrated solutions, however, the present invention does not require the entire Web application to be loaded at all times to be operational.

Abstract: An interface for maintaining man-machine communication with a control system for tuning appliances that influence the ambience, wherein a user command given during operation is converted to settings of these appliances in accordance with at least one predetermined conversion model, wherein the conversion model is a three-dimensional one, with parameter axes that refer to predetermined aspects of ambience, and in that the conversion model possesses adjustable discrete values pertaining to these aspects of ambience, and that the model provides an unambiguous interrelation that is continuous between said discrete values, linking a user command to the ensuing settings of the appliance depending on said values of the ambience aspects and the given user command.

Abstract: Battery cells having lithium intercalation anodes protected by surface coatings and active sulfur cathodes, and methods for their fabrication, provide improved battery cell performance.

Abstract: A computer bus system comprises: a direct address bus; at least one bus master device and at least one bus slave device, the bus master device and bus slave device being connected to the bus so that the bus master device may communicate with the bus slave device over the bus. The bus has an address space assigned to different devices connected to the bus and is a multiplexed address/data bus for transferring blocks of data (63,76) in a direct address transaction (60) between the devices. Each direct address transaction (60) comprises a burst transaction (61) having an address phase (12,62) with a bus space address value (62) followed by a data phase (63). The bus slave device includes an indirect address device addressable in an indirect address transaction (70) that has an address register load transaction (71) followed by a data register load transaction (72).

Abstract: Embodiments of the present invention relate to the determination of analyte characteristics based upon binding properties using mass analysis and differential labeling reagents.

Abstract: A computer bus system comprises: a direct address bus; at least one bus master device and at least one bus slave device, the bus master device and bus slave device being connected to the bus so that the bus master device may communicate with the bus slave device over the bus. The bus has an address space assigned to different devices connected to the bus and is a multiplexed address/data bus for transferring blocks of data (63,76) in a direct address transaction (60) between the devices. Each direct address transaction (60) comprises a burst transaction (61) having an address phase (12,62) with a bus space address value (62) followed by a data phase (63). The bus slave device includes an indirect address device addressable in an indirect address transaction (70) that has an address register load transaction (71) followed by a data register load transaction (72).

Abstract: A device for changing a termination voltage of a differential data bus having a first and second data bus. The device comprises a first adjustable termination path connectable to the first data bus and a second adjustable termination path connectable to the second data bus. The device further comprises a switch connectable in parallel with the first adjustable termination path and the second adjustable termination path.

Abstract: A method of comparing multiple seismic survey data sets of a reservoir, is provided, wherein a first seismic survey data set is taken at a first time and a second seismic survey data set is taken at a second time, to detect changes in the reservoir between the first time and the second time. Generally, the method comprises design of a crossequalization function for the second data set based on a comparison of unchanging portions of the two data sets. Also provided is a processing method for preparing each survey according to similar processing steps with information taken from each survey.

Abstract: The invention relates to a process for preparing a food ingredient suitable for use as a fat replacer, the process comprising the steps of: (a) forming an aqueous slurry of ground cereal, the slurry having a dry solids content of 10 to 50 weight percent; (b) enzymatically digesting the slurry at 60-95.degree. C. with an .alpha.-amylase enzyme capable of being deactivated by temperatures below 100.degree. C., whereby the enzymatic digestion is effected without any significant protein degradation; and (c) thermally deactivating the .alpha.-amylase enzyme. The products of this process are useful as fat replacers in a wide variety of foods, including baked products, dairy products and meat products. Also disclosed is the use of certain products as fat replacers in food.

Abstract: This invention describes carrier-drug conjugates prepared from disulfide analogs of the calicheamicin family of potent antitumor antibiotics and their derivatives, as well as similar analogs from related antitumor antibiotics such as the esperamicins. The carrier can be an antibody, growth factor, or steroid which targets an undesired population of cells, such as those of a tumor. Whole protein carriers as well as their antigen-recognizing fragments and their chemically or genetically manipulated counterparts are useful for the targeting portion of the conjugates. This invention includes compounds required for the synthesis of these conjugates, appropriate pharmaceutical compositions of the carrier-drug conjugates, and their method of use.

Abstract: This invention describes carrier-drug conjugates prepared from disulfide analogs of the calicheamicin family of potent antitumor antibiotics and their derivatives, as well as similar analogs from related antitumor antibiotics such as the esperamicins. The carrier can be an antibody, growth factor, or steroid which targets an undesired population of cells, such as those of a tumor. Whole protein carriers as well as their antigen-recognizing fragments and their chemically or genetically manipulated counterparts are useful for the targeting portion of the conjugates. This invention includes compounds required for the synthesis of these conjugates, appropriate pharmaceutical compositions of the carrier-drug conjugates, and their method of use.

Abstract: This invention describes carrier-drug conjugates prepared from disulfide analogs of the calicheamicin family of potent antitumor antibiotics and their derivatives, as well as similar analogs from related antitumor antibiotics such as the esperamicins. The carrier can be an antibody, growth factor, or steroid which targets an undesired population of cells, such as those of a tumor. Whole protein carriers as well as their antigen-recognizing fragments and their chemically or genetically manipulated counterparts are useful for the targeting portion of the conjugates. This invention includes compounds required for the synthesis of these conjugates, appropriate pharmaceutical compositions of the carrier-drug conjugates, and their method of use.

Abstract: This invention describes carrier-drug conjugates prepared from disulfide analogs of the calicheamicin family of potent antitumor antibiotics and their derivatives, as well as similar analogs from related antitumor antibiotics such as the esperamicins. The carrier can be an antibody, growth factor, or steroid which targets an undesired population of cells, such as those of a tumor. Whole protein carriers as well as their antigen-recognizing fragments and their chemically or genetically manipulated counterparts are useful for the targeting portion of the conjugates. This invention includes compounds required for the synthesis of these conjugates, appropriate pharmaceutical compositions of the carrier-drug conjugates, and their method of use.

Abstract: A continuous boiling water unit is disclosed and comprises a water heating tank (1) containing an electric heating element (2) near the bottom of the tank (1) and a level control tank (3) mounted alongside the heating tank (1). An interconnecting steam communication port (21) is located between the level control tank (3) and the heating tank (1), together with a draw-off connection (23) and a flow connection (10). There further comprises an electronic temperature sensor in the form of a thermister (50) operable to sense the temperature of water in the heating tank (1), and upon sensing boiling of the water in the heating tank (1), operable to cause cut-off of the supply to the heating element (2).

Abstract: A device for illuminating residence information. More specifically, it relates to a device which can be quickly and easily installed on a new or existing vertical lamppost and connected to a power supply for illuminating the resident's name and/or street number.