Abstract: Compounds of the Formula I: ##STR1## and pharmaceutically acceptable salts thereof are inhibitors of leukotriene biosynthesis. These compounds inhibit lipoxygenase, thus preventing the metabolism of arachidonic acid to the leukotrienes. These compounds are thus useful in the treatment of asthma, allergic disorders, inflammation, skin diseases and certain cardiovascular disorders.

Abstract: 3-Hydroxybenzo[b]thiophene derivatives, such as 2-aralkyl, 2-alkyl and 2-alkenyl-3-hydroxybenzo[b]-thiophenes, were prepared by, among other methods, ring closure of 2-(2-carboxy-phenylthio)-.alpha.-substituted acetic acids. These compounds are found to be useful in the treatment of pain, fever, inflammation, arthritic conditions, asthma, allergic disorders, skin diseases, cardiovascular disorders, psoriasis, inflammatory diseases and other prostaglandin and/or leukotriene mediated diseases.

Abstract: New magnetic hydride Nd.sub.2 Fe.sub.14 BH.sub.x (0<x<5) and family corresponding to other rare earths and yttrium. Possible substitution of Fe by Co. Preparation from Nd.sub.2 Fe.sub.14 B by hydrogenation (ambient temperature; pH.sub.2 >20 bar), which can be reversed to give powdered Nd.sub.2 Fe.sub.14 B. Remarkable magnetic properties.

Abstract: Described are derivatives of glycolipids with substituted steroids bridged via a medium length hydrocarbon chain to 1-thio-D-mannopyranoses or 1-thio-L-fucopyranoses. These compounds protect an immunocompromised human or animal host against opportunistic infection by virtue of their immunostimulant properties.

Abstract: A method for the analysis of particles in suspension in a fluid having a conductivity different from that of the particles, in particular a method for the analysis of blood particles is disclosed. The method includes the following steps: passing the fluid through an orifice, applying an electronic signal across the orifice, and producing electronic pulses corresponding to the changes in the signal level caused by the passage of the particles through the orifice. The invention is also concerned with a device for carrying out the method.

Abstract: N-arylated oxazolidine-2-one derivatives corresponding to the formula: ##STR1## and of S(+) configuration, A representing in this case the hydroxyl radical or of R (+) configuration, A designating then the N-methylamino group, as well as the acid addition salts thereof.Application in therapeutics more particularly as monoamine oxidase inhibitors.

Abstract: Apparatus for sample transfer and analysis by centrifugation, comprising a rotor having rotary joints at its periphery, to which cuvette carriers are connected so as to be able to perform a tipping movement through an angle of 90.degree., a locking device for locking the cuvette carriers in an inclined position, and cuvette assemblies for use in the cuvette carriers, the rotor preferably being in the form of a rotary beam at the two ends of which two cuvette carriers are disposed, and the cuvette carrier is in the form of a comb so that the teeth engage between the cuvette rows of the cuvette assembly. This apparatus enables samples to be transferred without mixing the cuvette contents.

Abstract: Disclosed is a chiral, total synthesis of thienamycin from D-glucose which proceeds via intermediates I, II and III to known aldehyde IV which is known to be useful in the total synthesis of thienamycin (V): ##STR1## wherein: R is lower alkyl having 1-6 carbon atoms or bi-valent alkyl having 2-6 carbon atoms which joins the two sulfur atoms; R.sup.1 is lower alkyl or aralkyl, such as benzyl and the like; and R.sup.2 is hydrogen or a removable protecting group, such as triorganosilyl wherein the organo groups are independently selected from lower alkyl, phenyl and phenylloweralkyl.

Abstract: There are disclosed nor-tropane derivatives substituted at the 3 position with aroylamino or heteroaroylamino and substituted at the 8 position with benzyl, substituted benzyl, 2-methyl thiophene, 3-methyl thiophene, 2-methyl furan or cyclohexylmethyl. The compounds are prepared by condensing the carboxylic acids corresponding to said aroyl or heteroaroyl group with the corresponding .beta.-3-amino-8-substituted nor-tropanes. The compounds possess neuroleptic properties.

Abstract: Compounds of the Formula I: ##STR1## and pharmaceutically acceptable salts thereof are inhibitors of leukotriene biosynthesis. These compounds inhibit lipoxygenase, thus preventing the metabolism of arachidonic acid to the leukotrienes. These compounds are thus useful in the treatment of asthma, allergic disorders, inflammation, skin diseases and certain cardiovascular disorders.

Abstract: A compound of the formula ##STR1## where R is selected from the group consisting of CH.sub.3 --CO--(CH.sub.2).sub.2 --O--, ##STR2## The compounds are useful in treating depression.

Abstract: Phosphatidyl inositol analogs are found to be effective phospholipase C inhibitors and thereby potent anti-inflammatory and analgesic agents. These phosphatidyl inositol analogs are prepared by condensation of a protected inositol with a substituted phosphonic or phosphorous acid followed by removal of protecting groups.

Abstract: The present invention concerns novel heterocyclic aminoalcoyl derivatives having the formula: ##STR1## wherein n=1, 2 or 3; A represents a nitrogen atom or the CH group, X=CH.sub.2 or CH.sub.2 O; R represents a phenyl nucleus possibly substituted; NR.sub.1 R.sub.2 =amino, methylamino, N,N-dialkylamino or an heterocyclic radical; and R.sub.3 =H, halogen, alkyl, alkyloxy or methoxy.These derivatives are useful as drugs, especially as analgesics and antidepressants.

Abstract: Disclosed is a chiral, total synthesis of thienamycin from D-glucose which proceeds via intermediates I, II, III and IV to known lactone V which is known to be useful via acid VI in the total synthesis of thienamycin (VII): ##STR1## wherein R.sup.1 is hydrogen or a removable protecting group; R is a removable protecting group.

Abstract: Process for preparing a para-quinone or ortho-quinone derivative, possibly alkoxylated or aryloxylated, which consists in oxidizing respectively the corresponding hydroquinone or pyrocatechic derivative, by means of the complex prepared, in situ or separately, by combining a cuprous salt, a hydrocarbon substituted by a cyano group and molecular oxygen, the oxidation being possibly carried out in the presence of an alkoxylating or aryloxylating agent of the hydroxylated derivative type.

Abstract: Derivatives corresponding to the general formula: ##STR1## in which Ar represents a phenyl group; a phenyl group substituted by a halogen atom or by a trifluoromethyl group; or the (chloro-3 fluoro-4) phenyl group and n is either equal to zero or equal to 1 in which case X is a chain chosen from the following: --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH--, --C.tbd.C--, --CH.sub.2 --O-- whose CH.sub.2 group is linked to Ar.These compounds are useful as medicaments more especially for the treatment of troubles of the central nervous system and senescence.

Abstract: There are disclosed nor-tropane derivatives substituted at the 3 position with aroylamino or heteroaroylamino and substituted at the 8 position with benzyl, substituted benzyl, 2-methyl thiophene, 3-methyl thiophene, 2-methyl furan or cyclohexylmethyl. The compounds are prepared by condensing the carboxylic acids corresponding to said aroyl or heteroaroyl group with the corresponding .beta.-3-amino-8-substituted nor-tropanes. The compounds possess neuroleptic properties.

Abstract: Method of treating the central nervous system troubles such as the Parkinson's disease and the senescence troubles, generally treated by the B type monoamine oxidase inhibitors, which comprises administering internally to a human being requiring such treatment a therapeutically effective amount of N-aryl 5-aminomethyl oxazolidine-2-one derivatives.

Abstract: Compounds having analgesic activity are disclosed which have the general formula: ##STR1## wherein R.sub.1 is hydrogen, alkyl having 1 to 4 carbon atoms, cyclohexyl or benzyl; R is selected from the group consisting of alkyl having at least 4 carbon atoms; cyclohexyl; unsubstituted phenyl or phenyl substituted with one or more halogen atoms, methyl, methoxy, hydroxy, cyano, nitro, trifluoromethyl, carboxyl, ethoxycarbonyl, acetamido, methylsulfonyl, phenoxy, benzoyl, phenyl, .alpha.-hydroxybenzyl, cyclohexyl or carbamoyl; thienyl; pyridyl; naphthyl; naphthyl substituted with methoxy; adamantyl; and benzyl; and n is 1, 2 or 3, with the provisos that (1) when R is carboxyphenyl, benzoylphenyl, or (.alpha.-hydroxybenzyl) phenyl, n is not 3, and (2) when R is (.alpha.-hydroxy benzyl) phenyl, R.sub.1 is not benzyl, and acid addition salts thereof.

Abstract: A data byte element E located at position d in entry i of memory section M.sub.a having reference entry TR is addressed. Memory section M.sub.a is one section of a table in a data processory memory, such that each of the entries in section M.sub.a has a predetermined number (t) of elements E. Signals having values related to the values of i, t and TR of several memory sections are stored in a storage device and read out when the storage device is addressed. A signal related to the value of d is also derived as a result of read-out from the storage device. The signals having values related to the values of i, t, TR and d are combined to derive an addressing signal for element E in memory section M.sub.a of the table of the data processing memory. An address circuit for the data processing memory responds to the addressing signal to addressing element E in memory section M.sub.a.