Abstract: A system for delivering an implant device to a vascular site in a patient a delivery pusher apparatus, an implant device detachably connected to the delivery pusher apparatus by a tether having a distal end connected to a proximal end of the implant device, wherein the tether is substantially non-tensioned when connecting the implant device to the delivery pusher, and an electrical heating element configured coaxially around at least a portion of the tether, wherein heat generated by the heating element severs the tether at a point near the proximal end of the implant device.

Abstract: Embodiments of the present disclosure provide an introducer device and method for introducing a delivery apparatus into a patient's vasculature. Disclosed methods can include positioning a sleeve of an introducer sheath in a blood vessel of a patient, the sleeve having a lattice layer with a lumen therethrough, inserting a distal end portion of the delivery apparatus and a prosthetic heart valve into the lumen, and advancing the distal end portion of the delivery apparatus through the lumen from the proximal end to the distal end. The method can then include expanding the lumen from a first diameter smaller to a second diameter at least equal to the diameter of the prosthetic heart valve to allow passage of the prosthetic heart valve through the lumen, and returning the lumen of the sleeve to a diameter smaller than the second diameter after advancing the prosthetic heart valve through the lumen.

Abstract: Methods of braiding using a braiding mechanism are described. The braiding machine includes first and second annular members, the second annular member being concentric with the first annular member. A mandrel extends perpendicularly to and intersects a horizontal plane defined by a substantially circular region of the second annular member substantially at the center of the circular region. Each of the annular members has a plurality of tubular guide wires slideably mounted thereon and a plurality of wires extend from the mandrel through each of the tubular wire guides. The first annular member rotates circumferentially relative to the second annular member. The first plurality of tubular wire guides slides radially inward to align with the second annular member, and the second plurality of tubular wire guides slides radially outward so as to align with the first annular member.

Abstract: Embodiments of the present disclosure provide a delivery apparatus for a prosthetic heart valve. Disclosed delivery apparatuses can include a housing, a steerable shaft, a slide nut, and a threaded shaft disposed over the slide nut. The slide nut can have an external threaded surface and an internal surface comprising a slot. The threaded shaft can have an internal threaded surface engaging the external threaded surface of the slide nut. The delivery apparatus can further include an elongated nut guide extending into the slot of the nut to restrain the slide nut against rotation relative to the housing, and a pull wire having a proximal end portion extending into the housing and coupled to the slide nut, and a distal end portion coupled to a distal end portion of the steerable shaft. The threaded shaft can be rotatable relative to the housing to produce axial movement of the slide nut within the threaded shaft.

Abstract: The present disclosure relates to a method, adapted to be implemented in an electronic device adapted to be powered by a power source, the method comprising monitoring a variation of an input voltage and/or an input current received from the power source while the electronic device is powered by the power source; and aborting, according to the monitored variation, a first action performed by a power consuming component of the electronic device. The present disclosure also relates to corresponding device, system, computer readable program product and computer readable storage medium.

Abstract: Embodiments of the present disclosure provide an introducer device and methods for introducing a medical device into a patient's vasculature. In one embodiment, a method of using an introducer device including a housing, a hemostatic seal mounted within the housing, and a tube extending into the housing and movable longitudinally relative to the hemostatic seal between a proximal position and a distal position, includes moving the tube to the distal position such that the distal end of the tube extends through the hemostatic seal. The method further includes inserting a distal end portion of the medical device through the tube and into the patient's vasculature without contacting the hemostatic seal.

Abstract: Embodiments of the present disclosure provide a delivery apparatus for a prosthetic heart valve. Disclosed steerable catheters can include a handle, a steerable shaft extending from the handle, and a pull wire. The shaft can include a main lumen, an inner polymeric layer surrounding the main lumen, a braided layer surrounding the inner polymeric layer, and an outer polymeric layer surrounding the braided layer, the outer polymeric layer defining a pull wire lumen. The pull wire can extend from the handle and through the pull wire lumen and can have a distal end portion coupled to a distal end portion of the shaft.

Abstract: Embodiments of the present disclosure provide a delivery apparatus for a prosthetic heart valve. Disclosed delivery apparatuses can include a handle, a first shaft extending from the handle, a second shaft disposed around the first shaft, and a valve cover. The valve cover can be coupled to a distal end portion of the first shaft and can be configured to house a prosthetic heart valve in a radially compressed state. The valve cover can have an outer diameter greater than an outer diameter of the second shaft, and the first shaft and valve cover can be movable together in an axial direction relative to the second shaft.

Abstract: Methods and devices for treatment of a patient's cerebral aneurysm is described. The device includes a permeable shell having a radially constrained elongated state configured for delivery within a catheter lumen, an expanded state with a longitudinally shortened configuration relative to the radially constrained state, and a plurality of elongate filaments that are woven together to form a mesh. The proximal ends of each of the plurality of filaments are gathered by a proximal hub and the distal ends of each of the plurality of filaments are gathered by a distal hub. The proximal portion of the permeable shell includes a swellable polymer. The method includes advancing the implant in a microcatheter to a region of interest in the cerebral vasculature, deploying the implant within the cerebral aneurysm, and withdrawing the microcatheter from the region of interest after deploying the implant.

Abstract: A device including an optoelectric circuit that is configured to provide galvanic isolation between a first circuit and a second circuit is disclosed. The optoelectric circuit includes at least one non-inverting buffer and a metal semiconductor diode. The at least one non-inverting buffer is positioned between a collector of a phototransistor and an anode of a light emitting diode. The metal semiconductor diode is positioned between the collector of the phototransistor and the at least one non-inverting buffer.

Abstract: Methods for treatment of a cerebral aneurysm within a cerebral vasculature of a patient are described. A microcatheter and a device for treatment of the aneurysm are provided. The device is a self-expanding resilient permeable shell having a plurality of elongate resilient filaments with a woven structure. The plurality of filaments includes small and large filaments. The filaments are bundled and secured to each other at a proximal end. A ratio of the total cross-sectional area of small filaments to the total cross-sectional area of large filaments may be between 0.56 and 1.89. The distal end of the microcatheter is advanced to a region of interest within a cerebral artery. The device is advanced through the lumen and out of the distal end of the microcatheter such that the permeable shell deploys and expands within the cerebral aneurysm. The microcatheter is then withdrawn from the cerebral artery.

Abstract: An external power supply converts AC power to DC Power for a device. The external power supply and the device comprise circuits that provide early AC input failure detection so that the device can take measures such as to safe keep data as long as the external power supply continues to provide DC power to the device.

Abstract: Methods of braiding using a braiding mechanism are described. The braiding machine includes first and second annular members, the second annular member being concentric with the first annular member. A mandrel extends perpendicularly to and intersects a horizontal plane defined by a substantially circular region of the second annular member substantially at the center of the circular region. Each of the annular members has a plurality of tubular guide wires slideably mounted thereon and a plurality of wires extend from the mandrel through each of the tubular wire guides. The first annular member rotates circumferentially relative to the second annular member. The first plurality of tubular wire guides slides radially inward to align with the second annular member, and the second plurality of tubular wire guides slides radially outward so as to align with the first annular member.

Abstract: A device and method for intravascular treatment of an embolism, and particularly a pulmonary embolism, is disclosed herein. One aspect of the present technology, for example, is directed toward a clot treatment device that includes a support member having a plurality of first clot engagement members and second clot engagement members positioned about the circumference of a distal portion of the support member. In an undeployed state, individual first clot engagement members can be linear and have a first length, and individual second clot engagement members can be linear and have a second length that is less than the first length. The clot engagement members can be configured to penetrate clot material along an arcuate path and hold clot material to the clot treatment device.

Abstract: An assembly includes a prosthetic heart valve and a delivery apparatus for implanting the prosthetic heart valve within the native aortic valve of a patient. The prosthetic heart valve has a radially compressible and expandable metallic stent and a flexible valvular structure mounted within the stent. The delivery apparatus has a handle, a first shaft having a proximal end portion and a distal end portion, a second shaft extending co-axially through the first shaft and having a proximal end portion and a distal end portion, the proximal end portions of the first and second shafts extending distally from the handle, a valve cover coupled to the distal end portion of the first shaft, and a nose piece coupled to the distal end portion of the second shaft.

Abstract: Embodiments of the present disclosure provide an introducer device for introducing a medical device into a patient's vasculature. In one embodiment, the introducer device comprises a housing, a distal sheath adapted to be inserted into a patient's vasculature with the housing positioned outside of the patient's vasculature, a hemostatic seal mounted within the housing, and a tube positioned within the housing and movable longitudinally relative to the hemostatic seal between a proximal position and a distal position. In the proximal position, a distal end of the tube is positioned proximal to the hemostatic seal with the hemostatic seal closed. In the distal position, the distal end of the tube extends through the hemostatic seal and permits the medical device to be inserted through the housing and into the patient's vasculature without contacting the hemostatic seal.

Abstract: Methods of braiding using a braiding mechanism are described. The braiding mechanism includes a circular array of filament engagement elements, a mandrel extending from the center of the circular array, a plurality of actuators disposed operably about the circular array, and a rotating mechanism adapted to rotate one or more filaments. The circular array of filament engagement elements and the plurality of actuators are configured to move relative to one another. The plurality of filaments are loaded onto the mandrel and extend radially toward and contact the circumferential edge of the circular array of filament engagement elements. The plurality of actuators are operated to engage a first subset of the plurality of filaments and move the engaged filaments in a generally radial direction to a position beyond the circumferential edge of the circular array. The rotating mechanism is operated to move the engaged filaments about the mandrel axis.

Abstract: Methods for forming a tubular braid are described. The method for braiding includes providing a braiding mechanism including a disc, a mandrel, and a plurality of actuators. The disc defines a plane and a circumferential edge and the mandrel extends from a center of the disc. A plurality of filaments are loaded on the mandrel, each extending radially toward the circumferential edge and contacting the disc at a point of engagement. The plurality of actuators are operated to engage and move a first subset of filaments in a generally radial direction to a position beyond the circumferential edge. The disc or the engaged first subset are rotated relative to one another, thereby crossing the first subset over a second subset of filaments. The actuators are then operated to move the first subset to a radial position on the circumferential edge different from its previous point of engagement.

Abstract: A device and method for intravascular treatment of an embolism, and particularly a pulmonary embolism, is disclosed herein. One aspect of the present technology, for example, is directed toward a clot treatment device that includes a support member having a plurality of first clot engagement members and second clot engagement members positioned about the circumference of a distal portion of the support member. In an undeployed state, individual first clot engagement members can be linear and have a first length, and individual second clot engagement members can be linear and have a second length that is less than the first length. The clot engagement members can be configured to penetrate clot material along an arcuate path and hold clot material to the clot treatment device.

Abstract: Devices and methods for treatment of a patient's vasculature with some embodiments configured for delivery with a microcatheter for treatment of the cerebral vasculature of a patient. Some embodiments may include a permeable shell and inner structure configured to occlude blood flow therethrough.