Abstract: The present invention involves new nitrons carrying a positive charge, useful in trapping of free radicals and especially the superoxide radical, of general formula:

Abstract: The invention relates to the use of a liquid or semi-solid formulation of botulinum toxin for the preparation of a medicament intended to treat a disorder characterised by bladder spasms (e.g. urinary incontinence due to unstable bladder or unstable detrusor sphincter, voiding complications due to detrusor overactivity or unstable detrusor sphincter, urinary retention secondary to spastic sphincter or hypertrophied bladder neck and neurogenic bladder dysfunction secondary to Parkinson's disease, spinal cord injury, stroke or multiple sclerosis or characterised by a spasm reflex), wherein said medicament is for administration by infusion into the bladder or by other methods that do not involve injection into the bladder wall.

Abstract: The invention concerns the use of a thienylcyclohexylamine, on its own or associated with other substances with pharmaceutical activity, for preparing a medicine designed to prevent and/or treat pain and/or nociception.

Abstract: The invention relates to the use of a pre-synaptic neuromuscular blocking substance for preparing a medicament intended to treat a gland, organ or duct obstructed by a naturally formed stone. This method can be applied notably for salivary gland, gall bladder, kidney or pancreas stones.

Abstract: This equipment includes at least one U-shaped clip (1) whose lateral branches (10) have sections and widths such that they may be inserted in the vertebral bodies (100) of two vertebrae by impaction on the intermediate branch (11) of the clip (1), so as to rest along the cortical bones of the vertebral bodies, and whose intermediate branch (11) is deformable in such a way as to allow a reduction of the distance between the lateral branches (10); the intermediate branch, before implantation, has a length such that one of the lateral branches (10) may be positioned slightly above the cortical bone forming the plate of the subjacent vertebra while the other lateral branch (10) may be positioned slightly below the cortical bone forming the plate of the subjacent vertebra, and has, after deformation, a length such that the two lateral branches (10) may be brought closer to each other.

Abstract: The present invention involves new nitrons carrying a positive charge, useful in trapping of free radicals and especially the superoxide radical, of general formula:

Abstract: The invention relates to the use of a liquid or semi-solid formulation of botulinum toxin for the preparation of a medicament intended to treat a disorder characterised by bladder spasms (e.g. urinary incontinence due to unstable bladder or unstable detrusor sphincter, voiding complications due to detrusor overactivity or unstable detrusor sphincter, urinary retention secondary to spastic sphincter or hypertrophied bladder neck and neurogenic bladder dysfunction secondary to Parkinson's disease, spinal cord injury, stroke or multiple sclerosis or characterised by a spasm reflex), wherein said medicament is for administration by infusion into the bladder or by other methods that do not involve injection into the bladder wall.

Abstract: The invention concerns an intervertebral implant that includes a spacer designed firstly to assume an implantation shape in which the spacer has two opposed channels (3, 4) bordered by retaining wings (3a, 3b, 4a, 4b), intended to receive the two spinous processes of two vertebrae, and secondly an insertion shape in which the parts of the implant forming the channels (3, 4) are separated by a value (d), and on at least one of their sides are lacking the retaining wings (3a, 3b, 4a, 4b), characterised in that the implant (1) is made from a shape-memory material, so that the implant changes to its implantation shape when it is subjected to heat, and so that, in this implantation shape, the parts of the implant forming the channels (3, 4) are separated by a value (D) that is greater than the value(d) of the insertion shape, in order to ensure the separation of the spinous processes.

Abstract: The system comprises an improved document monitoring agent in which user evaluations are used to decide whether a changed document should be saved in the system or not. The evaluation of importance of the change in a document is performed by one or more users who collaboratively monitor a networked document, typically identified by a URL. By providing a user evaluation interface, it is possible for users to indicate their evaluation of the significance of the change. As such, only significantly changed documents, as indicated by the users themselves, are saved. Thus, a more efficient saving is obtained while at the same time reducing the risk of discarding potentially interesting changed documents which would have been discarded by conventional monitoring agents.

Abstract: A pontoon usable for supporting a load, the pontoon being towable on land and usable on water to support the load thereonto. The pontoon includes a hinge; a first platform attached to the hinge, said first platform including a first substantially buoyant body extending therefrom; a second platform attached to said hinge so that the first and second platforms are hingedly attached to each other, the second platform including a second substantially buoyant body extending therefrom; a first and a second wheel respectively reversibly attachable to the first and second platforms respectively substantially adjacent the first and second buoyant bodies; the first and second platforms being movable between a deployed configuration and a folded configuration wherein in the folded configuration, the pontoon is usable on water to support the load and in the folded configuration, the pontoon is towable on land.

Abstract: A pontoon usable for supporting a load, said pontoon being towable on land and usable on water to support the load thereonto. The pontoon includes a hinge; a first platform attached to said hinge, said first platform including a first substantially buoyant body extending therefrom; a second platform attached to said hinge so that said first and second platforms are hingedly attached to each other, said second platform including a second substantially buoyant body extending therefrom; a first and a second wheel respectively reversibly attachable to the first and second platforms respectively substantially adjacent the first and second buoyant bodies; the first and second platforms being movable between a deployed configuration and a folded configuration wherein in said folded configuration, the pontoon is usable on water to support the load and in the folded configuration, the pontoon is towable on land.

Abstract: The invention provides a device for holding strip sealing gaskets on a turbomachine nozzle, the nozzle being constituted by a plurality of sectors having guide vanes which extend between inner and outer platforms elements, at least one of said platform elements having a sealing strip (30) disposed radially in a space between said platform element and an adjacent structural element in order to provide fluid tightness between said elements, the corresponding strips of two adjacent sectors touching, and their joint being covered by a joint cover (31) disposed between said strips, and by a holding member for holding said strips in the sealing position.

Abstract: A method for manufacturing a FBG having improved performances and an annealing-trimming apparatus for making the same are provided. The trimming and the annealing steps are advantageously combined into a single process in order to efficiently fabricate complex FBG filters with improved performance. The method comprises the steps of UV-writing a FBG in an optical fiber prior to annealing-trimming characteristics of the FBG by performing the sub-steps of monitoring characteristic data of the FBG while generating a controlled complex temperature profile along the FBG with a heating means according to the characteristic data for providing an accurate controlled annealing process of the FBG, thereby providing an accurate trimming thereof.

Abstract: The present invention relates to an intervertebral disc prostheses that comprise at least three pieces including an upper plate (1), a lower plate (2) and a mobile core (3) at least relative to the lower plate (2), the upper surface of the core (3) being in contact with at least a part of the lower surface of the upper plate (1), limit stops (22, 31) allowing friction to be limited, while limiting or preventing the movements of the core (3) relative to the lower plate (2), in translation and in rotation, respectively, along an axis substantially parallel to the lower plate (2) and about an axis substantially perpendicular to the lower plate (2) and the lower surface of the core (3) has at least one hole (41) facilitating sliding of the core (3) relative to the upper surface of the lower plate (2) with which it is in contact.

Abstract: The invention relates to an intersomatic implant designed to be inserted in the disk space defined between two adjacent vertebrae, namely an overlying vertebra and an underlying vertebra, for the purpose of reestablishing the anatomic space between the vertebrae, the implant being in the form of a cage (1) that is generally in the shape of a rectangular block having at least two sagittal walls (2, 3) interconnected at least by an anterior transverse wall (4) and by a posterior transverse wall (5), the walls (2 to 5) presenting rims (10) extending on one surface to define a first transverse face (8) and on the other side to define a second transverse face (9). According to the invention, the implant comprises: a first transverse face (8) presenting in the sagittal plane a convex profile congruent with the sagittal anatomic profile of an overlying vertebra; and a second transverse face presenting in the frontal plane a convex profile congruent with the frontal anatomic profile of an overlying vertebra.

Abstract: The invention concerns the use of a thienylcyclohexylamine, on its own or associated with other substances with pharmaceutical activity, for preparing a medicine designed to prevent and/or treat pain and/or nociception.