Patents by Inventor Pierre Renard

Pierre Renard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • (Thia) cycloalkyl[B]indole compounds as anti-inflammatory agents
    Patent number: 5635516
    Abstract: A compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3 and A are as defined in the description.
    Type: Grant
    Filed: June 27, 1995
    Date of Patent: June 3, 1997
    Assignee: Adir et Compagnie
    Inventors: Paul Caubere, Brigitte Jamart-Gregoire, Catherine Caubere, Dominique Manechez, Pierre Renard, Gerard Adam, Catherine Nguyen
  • Tricyclic oxime ethers
    Patent number: 5627203
    Abstract: The present invention relates to compounds of formula (I): ##STR1## wherein A, x, y, R.sub.1, R.sub.2 and R.sub.3 are as defined in the description. The compounds are useful for treating diseases requiring a selective serotonin reuptake site and 5-HT.sub.2c or 5-HT.sub.3 ligand.
    Type: Grant
    Filed: December 21, 1995
    Date of Patent: May 6, 1997
    Assignee: Adir et Compagnie
    Inventors: Sylvain Rault, Max Robba, Jean-Charles Lancelot, Herv e Prunier, Pierre Renard, Bruno Pfeiffer, B eatrice Guardiola-Lemaitre, Marie-Claire Rettori
  • 1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one and oxazolo[4,5-b]pyridin-2-(3H)-one compounds
    Patent number: 5618819
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## wherein R.sub.1, W and Y are as defined in the description, its geometric and/or optical useful as anti-algies.
    Type: Grant
    Filed: July 3, 1995
    Date of Patent: April 8, 1997
    Assignee: Adir et Compagnie
    Inventors: G erald Guillaumet, Marie-Claude Viaud, Laurence Savelon, Panayota Pavli, Pierre Renard, Bruno Pfeiffer, Daniel-Henri Caignard, Jean-Guy Bizot-Espiard, G erard Adam
  • Naphthylalkylamines
    Patent number: 5616614
    Abstract: The invention relates to a compound selected from those of general formula (I): ##STR1## in which R, R.sub.1, R.sub.2 and R.sub.3 are as defined in the specification, an optical isomer, and an addition salt thereof with a pharmaceutically-acceptable base. Medicinal product which is useful in the treatment of disorders linked to abnormal melatonin activity.
    Type: Grant
    Filed: January 25, 1995
    Date of Patent: April 1, 1997
    Assignee: Adir ET Compagnie
    Inventors: Said Yous, Daniel Lesieur, Patrick Depreux, B eatrice Guardiola-Lemaitre, G erard Adam, Pierre Renard, Daniel H. Caignard
  • O-arylmethyl-N-(thio)acylhydroxylamines
    Patent number: 5612368
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which Ar, X, R.sub.1 and R.sub.2 are as defined in the description and a medicinal product containing the same in order to treat a disorder of the melatoninergic system.
    Type: Grant
    Filed: October 25, 1995
    Date of Patent: March 18, 1997
    Assignee: Adir et Compagnie
    Inventors: Jean Andrieux, Michel Langlois, Pierre Renard, Philippe Delagrange
  • Arylalkyl (thio)amides
    Patent number: 5604261
    Abstract: A compound which is selected from those of formula (I) : ##STR1## in which A, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are as defined in the description, its optical isomers, and its addition salts thereof with a pharmaceutically-acceptable acid or base,and medicinal products containing the same which are useful for treating a disorder of the melatoninergic system.
    Type: Grant
    Filed: May 22, 1995
    Date of Patent: February 18, 1997
    Assignee: Adir Et Compagnie
    Inventors: Michel Langlois, Pierre Renard, G erard Adam
  • Tricyclic pyrrolopyrazine 5-HT.sub.3 -active compounds
    Patent number: 5599812
    Abstract: The present invention relates to a compound selected from these of formula (I): ##STR1## in which A and R.sub.1 are as defined in the description, and medicinal product containing the same which is useful for treating a disorder linked to the 5-HT.sub.3 receptors.
    Type: Grant
    Filed: April 29, 1994
    Date of Patent: February 4, 1997
    Assignee: Adir Et Compagnie
    Inventors: Sylvain Rault, Jean-Charles Lancelot, Herv e Prunier, Max Robba, Philippe Delagrange, Pierre Renard, G erard Adam
  • Trisubstituted naphthylalkylamides for disorders of the melatoninergic system
    Patent number: 5591775
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which R, R.sub.1, R.sub.2 and R.sub.3 are as defined herein for use in the treatment of a disorder of the melatoninergic system.
    Type: Grant
    Filed: December 6, 1994
    Date of Patent: January 7, 1997
    Assignee: Adir et Compagnie
    Inventors: Patrick Depreux, Hamid A. Mansour, Daniel Lesieur, Fran.cedilla.ois Lefoulon, Pierre Renard, Gerard Adam, Philippe Delagrange
  • Alpha-amino acid compounds
    Patent number: 5585390
    Abstract: Compounds of the general formula: ##STR1## wherein m, X, Y, A, R.sub.2 and R.sub.3 are defined in the description, and medicaments containing the same.
    Type: Grant
    Filed: May 9, 1995
    Date of Patent: December 17, 1996
    Assignee: Adir Et Compagnie
    Inventors: Muriel Duflos, Sylvie Robert-Piessard, Lucien Welin, Guillaume Le Baut, Daniel-Henri Caignard, Pierre Renard, G erard Adam
  • Alkylaminoindane compounds
    Patent number: 5569669
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.2', R.sub.2", R.sub.2'", R.sub.3 and n are as defined in the description, an optical isomer, and an addition salt thereof with a pharmaceutically-acceptable acid or base,and medicinal product containing the same useful for treating a mammal afflicted with a disorder associated to 5-HT.sub.1A or 5-HT.sub.2C receptors.
    Type: Grant
    Filed: March 10, 1995
    Date of Patent: October 29, 1996
    Assignee: Adir et Compagnie
    Inventors: G erald Guillaumet, Marie-Claude Viaud, Pierre Renard, G erard Adam, Daniel-Henri Caignard, B eatrice Guardiola-Lemaitre, Marie-Claire Rettori
  • Arylalkyl(thio) amides
    Patent number: 5554642
    Abstract: A compound which is selected from those of formula (I): ##STR1## in which A, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are as defined in the description,its optical isomers and its addition salts thereof with a pharmaceuticaliy-accepable acid or base,and medicinal products containing the same which are useful for treating a disorder of the melatoninergic system.
    Type: Grant
    Filed: May 22, 1995
    Date of Patent: September 10, 1996
    Assignee: Adir et Compagnie
    Inventors: Michel Langlois, Pierre Renard, G erard Adam
  • Trisubstituted Naphthylalkylamides
    Patent number: 5552418
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which R, R.sub.1, R.sub.2 and R.sub.3 are as defined in the specification,and a medicinal product containing said compound for treating a disorder of the melatoninergic system.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: September 3, 1996
    Assignee: Adir et Compagnie
    Inventors: Patrick Depreux, Hamid Ait Mansour, Daniel Lesieur, Fran.cedilla.ois Lefoulon, Pierre Renard, G erard Adam, Philippe Delagrange
  • (Aryl(alkyl)carbonyl)-heterocyclic compounds and their use in the treatment of anxiety and depression
    Patent number: 5534517
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## wherein Ar, n, B and A are as defined in the description, to their optical isomers, and to their addition salts there of with a pharmaceutically-acceptable acid or base. The compounds are useful for treating or preventing anxiety and depression.
    Type: Grant
    Filed: August 26, 1994
    Date of Patent: July 9, 1996
    Assignee: Adir Et Compagnie
    Inventors: Ousmane Diouf, Daniel Lesieur, Patrick Depreux, Beatrice Guardiola-Lemaitre, Daniel-Henri Caignard, Pierre Renard, Gerard Adam
  • Aminoalkyl benzoxazolinones and benzothiazolinones
    Patent number: 5534511
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3, X and n are as defined in the description, the optical isomers thereof, and the addition salts thereof with a pharmaceutically acceptable acid or base and medicinal product containing the same, useful for treating a mammal afflicted with a pathology associated with the sigma receptors.
    Type: Grant
    Filed: March 21, 1995
    Date of Patent: July 9, 1996
    Assignee: Adir et Compagnie
    Inventors: Ange Mouithys-Mickalad, Patrick Depreux, Daniel Lesieur, Gerard Adam, Daniel-Henri Caignard, Pierre Renard, Marie-Claire Rettori
  • New aminoalkylchromones, processes for the preparation thereof
    Patent number: 5519023
    Abstract: The invention relates to compounds of the general formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6 and Z are as defined in the description, their optical isomers and their addition salts with a pharmaceutically-acceptable acid or base and medicaments containing the same, useful in the treatment and prevention of stress, anxiety, and related ailments.
    Type: Grant
    Filed: July 2, 1993
    Date of Patent: May 21, 1996
    Assignee: Adir et Compagnie
    Inventors: Marc Payard, Genevieve Baziard-Mouysset, Gilbert De Saqui-Sannes, Beatrice Guardiola, Daniel-Henri Caignard, Pierre Renard, Gerard Adam
  • Aminoalkyl benzothiazolinones
    Patent number: 5512569
    Abstract: The invention relates to the compounds of formula (I): ##STR1## in which R.sub.1 and R.sup.2 are as defined in the description, the optical isomers thereof,and an addition salt thereof with a pharmaceutically-acceptable acid or base, and medicinal product useful for treating a mammal afflicted with a disease associated with sigma receptors.
    Type: Grant
    Filed: March 21, 1995
    Date of Patent: April 30, 1996
    Assignee: Adir et Compagnie
    Inventors: Hamid A. Mansour, Thierry Taverne, Raymond Houssin, Isabelle Lesieur, Patrick Depreux, Geard Adam, Daniel-Henri Caignard, Pierre Renard, Marie-Claire Rettori
  • Substituted piperazines for treatment of non-insulin-dependant diabetes
    Patent number: 5500426
    Abstract: A compound selected from those of formula (I): ##STR1## in which A represents ##STR2## X represents N--R.sub.4 or oxygen, and R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, n and m are as defined in the description,useful in improving glucose tolerance in the treatment of non-insulin-dependent diabetes.
    Type: Grant
    Filed: April 19, 1995
    Date of Patent: March 19, 1996
    Assignee: Adir et Compagnie
    Inventors: Jean-Jacques Godfroid, Aazdine Lamouri, Estera Touboul, Xuan Wang, Pierre Renard, Bruno Pfeiffer, Beatrice Guardiola
  • Substituted piperazines for treatment of non-insulin dependent diabetes
    Patent number: 5492912
    Abstract: A compound selected from those of formula (I): ##STR1## in which A represents ##STR2## X represents N-R.sub.4 or oxygen, and R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, n and m are as defined in the description, useful in improving glucose tolerance in the treatment of non-insulin-dependent diabetes.
    Type: Grant
    Filed: July 21, 1994
    Date of Patent: February 20, 1996
    Assignee: Adir et Compagnie
    Inventors: Jean-Jacques Godfroid, Aazdine Lamouri, Estera Touboul, Xuan Wang, Pierre Renard, Bruno Pfeiffer, Beatrice Guardiola
  • (Thia)cycloalkyl[B]indoles
    Patent number: 5491163
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3 and A are as defined in the description, and medicinal product containing the same in order to treat a mammal afflicted with a peroxydation phenomenom.
    Type: Grant
    Filed: July 19, 1994
    Date of Patent: February 13, 1996
    Assignee: Adir et Compagnie
    Inventors: Paul Caubere, Brigitte Jamart-Gregoire, Catherine Caubere, Jean-Guy Bizot-Espiard, Pierre Renard, Gerard Adam
  • .alpha.-amino acid compounds
    Patent number: 5470864
    Abstract: Compounds of the general formula: ##STR1## wherein m, X, Y, A, R.sub.2 and R.sub.3 are defined in the description.
    Type: Grant
    Filed: June 30, 1994
    Date of Patent: November 28, 1995
    Assignee: Adir et Compagnie
    Inventors: Muriel Duflos, Sylvie Robert-Piessard, Lucien Welin, Guillaume Le Baut, Daniel-Henri Caignard, Pierre Renard, Gerard Adam