Patents by Inventor Pietro Massardo

Pietro Massardo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080033043
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: June 14, 2007
    Publication date: February 7, 2008
    Applicant: BIOAVAIL LABORATORIES INTERNATIONAL S.R.L.
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Saleh
  • Publication number: 20080033044
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: June 21, 2007
    Publication date: February 7, 2008
    Applicant: BIOAVAIL LABORATORIES
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Saleh
  • Publication number: 20070293584
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: June 21, 2007
    Publication date: December 20, 2007
    Applicant: BIOAVAIL LABORATORIES INTERNATIONAL S.R.L.
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Saleh
  • Publication number: 20070281012
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: June 13, 2007
    Publication date: December 6, 2007
    Applicant: BIOAVAIL LABORATORIES INTERNATIONAL S.R.L.
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Saleh
  • Publication number: 20070276047
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: May 22, 2007
    Publication date: November 29, 2007
    Applicant: BIOVAIL LABORATORIES INTERNATIONAL S.R.L.
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Saleh
  • Publication number: 20070269516
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: May 22, 2007
    Publication date: November 22, 2007
    Applicant: BIOAVAIL LABORATORIES INTERNATIONAL S.R.L.
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Saleh
  • Patent number: 7241805
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Grant
    Filed: June 27, 2006
    Date of Patent: July 10, 2007
    Assignee: Biovail Laboratories, Inc.
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Ashty Saleh
  • Publication number: 20070072895
    Abstract: Two novel crystalline forms, designated form A and form B of the antibacterial agent 1-cyclopropyl-7-([S,S])-2,8-diazadicyclo[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinoline carboxylic acid hydrochloride of formula, the preparation thereof, and their pharmaceutical compositions are described. These crystalline forms, which are characterized by greater stability and ease of preparation and of formulation, can be produced by industrially applicable methods which comprises the steps of: a) suspending 1-cyclopropyl-7-([S,S])-2,8-diazadicyclo-[4.3.0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinoline carboxylic acid hydrochloride in a solvent selected from an alcohol and a polyalcohol, b) heating the mixture under reflux, p1 c) cooling, d) isolating the product which is separated, (form A) and, additionally, e) reslurrying the solid at reflux in a solvent selected from alcohols and polyols or mixtures thereof, in which the resulting mixture has an overall water content of between 2.
    Type: Application
    Filed: October 28, 2004
    Publication date: March 29, 2007
    Inventors: Stefano Turchetta, Pietro Massardo, Valentina Aromatario
  • Publication number: 20070027213
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: June 27, 2006
    Publication date: February 1, 2007
    Applicant: Biovail Laboratories International S.R.L.
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Ashty
  • Patent number: 7105681
    Abstract: Process for preparing sulfinyl derivatives of Formula 2, useful as inhibitors of gastric acid secretion, comprising the selective oxidation of the corresponding sulfides of formula 1, as represented in the following scheme The oxidation is performed with hydrogen peroxide in the presence of low amounts of a rhenium compound as catalyst, at a temperature from 0° C. to room temperature.
    Type: Grant
    Filed: June 10, 2005
    Date of Patent: September 12, 2006
    Assignee: Chemi SPA
    Inventors: Stefano Tur{overscore (c)}hetta, Pietro Massardo, Angela Tuozzi
  • Publication number: 20060128971
    Abstract: Process for preparing atorvastatin calcium salt in amorphous form comprising: a) dissolving the atorvastatin calcium salt in an organic solvent miscible with water, b) gradually adding said solution to water while stirring, c) filtering and vacuum drying the solid obtained.
    Type: Application
    Filed: April 25, 2003
    Publication date: June 15, 2006
    Inventors: Stefano Turchetta, Pietro Massardo, Angela Tuozzi
  • Publication number: 20060079716
    Abstract: A process is described for the preparation of N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-propaneamine comprising substitution of the sulfonyloxy group of the compound of the formula in which the substituents R and R? have the meanings stated in the description, in a solvent comprising an ionic liquid, to yield the tertiary amine of the formula and the subsequent deprotection thereof.
    Type: Application
    Filed: October 6, 2005
    Publication date: April 13, 2006
    Applicant: CHEMI SPA
    Inventors: Stefano Turchetta, Umberto Ciambecchini, Pietro Massardo
  • Publication number: 20060014798
    Abstract: The present invention relates to a mild and industrially applicable process for preparing sulfinyl derivatives of Formula (II), useful as inhibitors of gastric acid secretion, comprising the selective oxidation of the corresponding sulfides of Formula (I), as represented in scheme (I) and (II) in which said oxidation is performed with hydrogen peroxide in the presence of low amounts of a rhenium compound as catalyst, at a temperature from 0° C. to room temperature.
    Type: Application
    Filed: June 10, 2005
    Publication date: January 19, 2006
    Applicant: CHEMI SPA
    Inventors: Stefano Turchetta, Pietro Massardo, Angela Tuozzi
  • Publication number: 20050288509
    Abstract: A process for preparing bisphosphonic acids, characterized in that the reaction of synthesis is conducted in a reaction consisting of bisphosphonic acids.
    Type: Application
    Filed: November 25, 2002
    Publication date: December 29, 2005
    Inventors: Lorenzo De Ferra, Stefano Turchetta, Pietro Massardo, Paolo Casellato
  • Publication number: 20050222052
    Abstract: A method for preparing high purity azithromycin is described characterised in that the intermediate 9a-deoxo-9a-aza-9a-homoerythromycin A is crystallised and obtained at very high purity, the subsequent methylation reaction effected on said intermediate proceeding with very high specificity and conversion enabling azithromycin of particularly high purity to be obtained.
    Type: Application
    Filed: June 4, 2003
    Publication date: October 6, 2005
    Inventors: Stefano Turchetta, Pietro Massardo, Paolo Casellato
  • Publication number: 20050215793
    Abstract: A process for the preparation of 3-pyridil-1-hydroxyethyliden-1,1-biphosphonic acid monosodium salt of formula in an amorphous form, preferably lyophilized, and its pharmaceutical compositions are described.
    Type: Application
    Filed: February 28, 2005
    Publication date: September 29, 2005
    Applicant: CHEMI SPA
    Inventors: Stefano Turchetta, Pietro Massardo, Umberto Ciambecchini
  • Patent number: 6897339
    Abstract: Purification process of iohexol comprising the treatment of said product with 1-methoxy-2-propanol either alone or mixed with other solvents.
    Type: Grant
    Filed: April 9, 2002
    Date of Patent: May 24, 2005
    Assignee: Chemi, S.p.A.
    Inventors: Stefano Turchetta, Pietro Massardo, Valentina Aromatario
  • Publication number: 20050014798
    Abstract: Two new polymorphous crystalline forms of rosiglitazone maleate, termed respectively form I and II, and the methods for selectively obtaining each form are described and characterized.
    Type: Application
    Filed: April 16, 2004
    Publication date: January 20, 2005
    Applicant: CHEMI SPA
    Inventors: Stefano Turchetta, Pietro Massardo, Valentina Aromatario
  • Publication number: 20040106828
    Abstract: Purification process of iohexol comprising the treatment of said product with 1-methoxy-2-propanol either alone or mixed with other solvents.
    Type: Application
    Filed: October 10, 2003
    Publication date: June 3, 2004
    Inventors: Stefano Turchetta, Pietro Massardo, Valentina Aromatario
  • Patent number: 6645742
    Abstract: The present invention relates to a purifying process for phosphatidylserine, the latter being prepared by trans-phosphatidylation of phosphatidylcholine with serine in presence of the enzyme D-phospholipase and containing as impurities hydrophilic compounds, proteins and inorganic salts.
    Type: Grant
    Filed: October 18, 2001
    Date of Patent: November 11, 2003
    Assignee: Chemi S.p.A.
    Inventors: Lorenzo De Ferra, Pietro Massardo