Abstract: A superconducting integrated circuit design method based on placement and routing by different-layer JTLs comprises: cutting a bias line at a cell data interface of a cell library, and reserving a position of a via; placing and arranging cells on a logic cell layer according to a schematic circuit logic diagram; connecting clock lines of each of the cells by using a JTL and a splitter of the logic cell layer; and performing data connection on each of the cells by using JTLs of a transverse JTL routing layer and a longitudinal JTL routing layer which are not in the same layer as the logic cell layer, wherein the JTL of the transverse JTL routing layer is used as a transverse routing cell for data between the cells, the JTL of the longitudinal JTL routing layer is used as a longitudinal routing cell for data between the cells.

Abstract: Disclosed are a method of manufacturing a polyethylene membrane comprising: stretching a polyethylene film in a first direction during a first stretching; attaching a plurality of rods on side edges of the polyethylene film; attaching a tape on the polyethylene film; stretching the polyethylene film having the rods attached thereto in a second direction during a second stretching; and annealing the polyethylene film after the second stretching. The second direction can be a transverse direction of the first direction, and the first stretching and the second stretching can be performed at the same (or higher) temperature and the same stretching speed as each other.

Abstract: Provided is a simple and easy to operate device for collecting and extracting fecal samples. The collection device of the invention comprises a top cap mounted with a sample collection means, a middle cap inserted with an elastic sealing funnel, and a bottom container having only one opening. The device can collect fecal samples with a quantitative sampling accuracy comparable to that of the conventional weighing method. It can also be easily adapted to automated multi-sample extraction and immunoassays.

Abstract: The present disclosure relates to a field of dry etching technology. The present disclosure provides an ultra-large area scanning reactive ion etching machine and an etching method thereof. The ultra-large area scanning reactive ion etching machine includes: an injection chamber (101), an etching reaction chamber (102), a transition chamber (103), and an etching ion generation chamber (104). By moving a sample holder (111) among the injection chamber (100), the etching reaction chamber (102) and the transition chamber (103) in a scanning direction, a scanning etching is performed on a sample (100) placed on the sample holder (111), which may realize a large-area, uniform and efficient etching.

Abstract: An all-solid-state battery system having a solid-state electrolyte composite is provided. The solid-state electrolyte composite includes a porous framework providing support and mechanical strength for the solid-state electrolyte composite and a plurality of ionic conductors filling voids of the porous framework for maximizing ionic conductance of the solid-state electrolyte composite. The porous framework may be made of ultra-high-molecular-weight polyethylene (UHMWPE) polymers and the plurality of ionic conductors may be made of poly(ethylene oxide)-LiN(SO2CF3)2 (PEO-LiTFSI) polymers. The all-solid-state battery system includes battery cells each including a cathode current collector, a cathode disposed beneath and connected to the cathode current collector, the solid-state electrolyte composite disposed beneath and connected to the cathode, an anode disposed beneath and connected to the solid-state electrolyte composite, and an anode current collector disposed beneath and connected to the anode.

Abstract: The present disclosure proposes an apparatus for coating photoresist and a method for coating photoresist. The apparatus for coating photoresist comprises a gas supply unit (10) configured to supply gas to a photoresist application unit (20); wherein the photoresist application unit (20) comprises: a device cavity (202) enclosed by sidewalls, a bottom plate and a cover plate (206), a rotation platform (204) configured to carry a substrate (205) and bring the substrate to rotate; a guide unit conformal with the substrate, and configured to uniformly blow the gas supplied by the gas supply unit over a surface of the substrate on which the photoresist is coated; and a gas extraction unit (203) configured to extract gas from the device cavity (202). The present disclosure realizes uniformly and rapidly coating the photoresist on a large substrate.

Abstract: The embodiments of the present disclosure propose a negative refraction imaging lithographic method and equipment. The lithographic method includes: coating photoresist on a device substrate; fabricating a negative refraction imaging structure, wherein the negative refraction imaging structure exhibits optical negative refraction in response to beam emitted by exposure source; pressing a mask to be close to the negative refraction imaging structure; disposing the mask and the negative refraction imaging structure above the device substrate at a projection distance; and light emitted by the exposure source passes through the mask, the negative refraction imaging structure, the projection gap and is sequentially projected onto the photoresist for exposure.

Abstract: This invention relates to a method and process which dynamically monitors data from an on-going randomized clinical trial associated with a drug, device, or treatment. In one embodiment, the present invention automatically and continuously unblinds the study data without human involvement. In one embodiment, a complete trace of statistical parameters such as treatment effect, trend ratio, maximum trend ratio, mean trend ratio, minimum sample size ratio, confidence interval and conditional power are calculated continuously at all points along the information time. In one embodiment, the invention discloses a graphical user interface-based method and system to early conclude a decision, i.e., futile, promising, sample size re-estimate, for an on-going clinical trial. In one embodiment, exact type I error rate control, median unbiased estimate of treatment effect, and exact two-sided confidence interval can be continuously calculated.

Abstract: A device for the extraction of an analyte from a fecal sample, the device comprising a housing comprising a detachable cap with an integral spatula, within the housing is an extraction buffer that solubilizes feces into a liquid phase and a solid phase and a separation gel that is submerged within the extraction buffer and positioned at a bottom of the housing, wherein the separation gel when under a sufficient centrifugal force has a separating density that is equal to or greater than a liquid phase density of the liquid phase and less than a solid phase density of the solid phase, thereby permitting separation of the liquid and solid phases, further wherein the separating density is between 0.098 and 1.08 g/cm3.

Abstract: Disclosed are a method of manufacturing a polyethylene membrane comprising: stretching a polyethylene film in a first direction during a first stretching; attaching a plurality of rods on side edges of the polyethylene film; attaching a tape on the polyethylene film; stretching the polyethylene film having the rods attached thereto in a second direction during a second stretching; and annealing the polyethylene film after the second stretching. The second direction can be a transverse direction of the first direction, and the first stretching and the second stretching can be performed at the same (or higher) temperature and the same stretching speed as each other.

Abstract: The present disclosure proposes an apparatus for coating photoresist and a method for coating photoresist. The apparatus for coating photoresist comprises a gas supply unit (10) configured to supply gas to a photoresist application unit (20); wherein the photoresist application unit (20) comprises: a device cavity (202) enclosed by sidewalls, a bottom plate and a cover plate (206), a rotation platform (204) configured to carry a substrate (205) and bring the substrate to rotate; a guide unit conformal with the substrate, and configured to uniformly blow the gas supplied by the gas supply unit over a surface of the substrate on which the photoresist is coated; and a gas extraction unit (203) configured to extract gas from the device cavity (202). The present disclosure realizes uniformly and rapidly coating the photoresist on a large substrate.

Abstract: The present invention relates to novel macrocyclic sulfondiimine compounds of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).

Abstract: The present disclosure provides a secondary imaging optical lithography method and apparatus.

Abstract: An ultra high molecular weight polyethylene (UHMWPE) membrane has at least one nanoporous UHMWPE film, where each of the nanoporous UHMWPE film is biaxial oriented with a thickness of 0.1 to 12 ?m and pores that exclude particles in excess of 10 nm with a total porosity of 65 to 75 percent. The nanoporous UHMWPE film can be coated or laminated by a hydrophilic polymer to form a Janus membrane and can be made with a multilayer composite structure. The UHMWPE membrane can be used in a device for molecular distillation (MD), reverse osmosis (RO), or forward osmosis (FO).

Abstract: Provided is a simple and easy to operate device for collecting and extracting fecal samples. The collection device of the invention comprises a top cap mounted with a sample collection means, a middle cap inserted with an elastic sealing funnel, and a bottom container having only one opening. The device can collect fecal samples with a quantitative sampling accuracy comparable to that of the conventional weighing method. It can also be easily adapted to automated multi-sample extraction and immunoassays.

Abstract: Methods are provided for producing a biaxially oriented nanoporous UHMWPE membrane. The method can include combining a petroleum jelly, an ultra-high-molecular-weight polyethylene (UHMWPE), and an antioxidant, forming a suspension, feeding the suspension into an extruder to produce a gel filament, pressing the gel filament to form a gel film, subjecting the gel film to an annealing temperature, and extracting the petroleum jelly from the gel film.

Abstract: The present disclosure relates to a compound of general Formula (1) which can be used as an electrode material, an electrode comprising said compound, and a battery cell comprising at least one of said electrode.

Abstract: A magnesium halide adduct represented by the formula (I): MgX2.mROH.nE.pH2O, in which X is chlorine, bromine, a C1-C12 alkoxy, a C3-C10 cycloalkoxy or a C6-C10 aryloxy, with the proviso that at least one X is chlorine or bromine; R is a C1-C12 alkyl, a C3-C10 cycloalkyl or a C6-C10 aryl; E is an o-alkoxybenzoate compound represented by the formula (II): in which R1 and R2 groups are independently a C1-C12 linear or branched alkyl, a C3-C10 cycloalkyl, a C6-C10 aryl, a C7-C10 alkaryl or an C7-C10 aralkyl, the R1 and R2 groups are identical to or different from the R group; m is in a range of from 1.0 to 5.0; n is in a range of from 0.001 to 0.5; and p is in a range of from 0 to 0.8, is disclosed. A catalyst component useful in olefin polymerization, which comprises a reaction product of (1) the magnesium halide adduct, (2) a titanium compound, and optionally (3) an electron donor compound, is also disclosed.

Abstract: The present disclosure relates to pharmaceutical compositions of pyrimidinedione derivative compounds and methods of preparing and uses thereof. The disclosure also relates to methods of enhancing bioavailability of pyrimidinedione derivative compounds in pharmaceutical compositions administered to a subject and methods of reducing the amount of a pyrimidinedione derivative compound in a pharmaceutical composition while achieving the same bioavailability in a subject.

Abstract: The present invention relates to novel macrocyclic sulfondiimine compounds of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).