Abstract: Antibodies and antigen binding fragments that bind to neublastin polypeptides are disclosed. Also disclosed are methods of using the antibodies and antigen binding fragments in assays for detecting the presence or amount of endogenous and/or exogenous neublastin in a sample and in methods of antagonizing neublastin bioactivity.

Abstract: An oven apparatus for solidifying a coating on a housing includes a supporting module, a curing module, and a transporting module. The supporting module includes a frame and of periphery boards around the frame, the frame includes at least two stacked frame sections. The curing module and the heating module are respectively mounted to the frame sections, the transporting module circularly transports the housing and passes though the heating module and heating module.

Abstract: Thermochromic microparticles including vanadium dioxide (VO2) particles of a rutile crystal phase (R phase), and titanium dioxide (TiO2) particles of the rutile crystal phase (R phase), wherein at least one of the vanadium dioxide (VO2) particles of a rutile crystal phase (R phase) is grown like a rod on the titanium dioxide (TiO2) particles to be larger than sizes of the titanium dioxide (TiO2) particles.

Abstract: A method for implementing photoelectric mutex, an Ethernet photoelectric mutex interface device, and network equipment are provided. The Ethernet photoelectric mutex interface device includes a channel switching module, a first Ethernet physical layer (PHY) chip, and a second Ethernet PHY chip. The channel switching module is connected to the first Ethernet PHY chip through a first interface and connected to the second Ethernet PHY chip through a second interface respectively, and is adapted to perform data transmission through the first Ethernet PHY chip and when a presence signal of an optical interface data transmission module is detected, perform data transmission through the second Ethernet PHY chip. Thus, a cost of equipment for implementing a photoelectric mutex function in an Ethernet is reduced, and a utilization rate of transmission resources is improved.

Abstract: The invention provides methods for identifying modulators of cardiac troponin I activity as well as methods for using N-terminally truncated forms of cTnI to monitor the function of the circulatory system in general, and the heart in particular, of an organism such as man. Additionally, the invention provides methods of treating circulatory diseases, disorders or conditions, such as cardiac diseases and conditions, by administering a therapeutically effective amount of a modulator of the N-terminal structure of cTnI, such as a molecule capable of binding to the N-terminus of full-length cTnI, a molecule that modulates cTnI phosphorylation and/or N-terminal proteolytic cleavage, or by administering N-terminally truncated cTnI or a polynucleotide encoding that protein or polypeptide.

Abstract: The invention provides methods for identifying modulators of mammalian, e.g., human, h2-calponin, the calponin isoform of relatively neutral pI. H2-calponin exerts an effect on the migration and proliferation of a variety of muscle (smooth muscle) and non-muscle cells and is an actin filament-associated regulatory protein influencing the structure of the actin cytoskeleton. Modulators of the activity levels of this protein are useful in preventing, ameliorating, or treating a variety of diseases, disorders or conditions characterized by aberrant cell migration and/or cell proliferation.

Abstract: The invention provides methods for diagnosing, preventing, treating, determining the likelihood of developing, or ameliorating a symptom associated with, cardiac disease by administering a therapeutically effective amount of a modulator, such as an inducer, of the posttranslational production of N-terminally truncated forms of cardiac troponin T. An exemplary modulator in the form of an inducer is a Calpain inducer; an exemplary modulator in the form of an inhibitor is an inhibitor of aCalpain inhibitor, such as a mu-Calpain inhibitor.

Abstract: An exemplary rotary bracket system includes at least one rotary bracket (10) and at least one anti-vibration system (20). The rotary bracket has a rotary shaft (12). The anti-vibration system includes at least one fixture member (21) and at least one shock-absorber assembly (23) connected to the at least one fixture member. The at least one fixture member fits around the rotary shaft of the at least one rotary bracket such that the rotary shaft is rotatable in the at least one fixture member.

Abstract: The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here signalin-related genes, which are involved in a signal transduction induced by members of the TGF? superfamily. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.

Abstract: It is shown here that hedgehog proteins possess novel activities beyond phenotype specification. Using cultures derived from the embryonic day 14.5 (E14.5) rat ventral mesencephalon, we show that hedgehog is also trophic for dopaminergic neurons. Interestingly, hedgehog not only promotes dopaminergic neuron survival, but also promotes the survival of midbrain GABA-immunoreactive (GABA-ir) neurons.

Abstract: It is shown here that hedgehog proteins possess novel activities beyond phenotype specification. Using cultures derived from the embryonic day 14.5 (E14.5) rat ventral mesencephalon, we show that hedgehog is also trophic for dopaminergic neurons. Interestingly, hedgehog not only promotes dopaminergic neuron survival, but also promotes the survival of midbrain GABA-immunoreactive (GABA-ir) neurons.

Abstract: The invention provides methods for identifying modulators of cardiac troponin I activity as well as methods for using N-terminally truncated forms of cTnI to monitor the function of the circulatory system in general, and the heart in particular, of an organism such as man. Additionally, the invention provides methods of treating circulatory diseases, disorders or conditions, such as cardiac diseases and conditions, by administering a therapeutically effective amount of a modulator of the N-terminal structure of cTnI, such as a molecule capable of binding to the N-terminus of full-length cTnI, a molecule that modulates cTnI phosphorylation and/or N-terminal proteolytic cleavage, or by administering N-terminally truncated cTnI or a polynucleotide encoding that protein or polypeptide.

Abstract: The present invention relates to the device for animal inspection and quarantine and the preparation method thereof. The present invention is especially applicable to the detection of the pathogen of bovine spongiform encephalopathy (BSE) (also known as “mad cow disease”). The present invention employs a piezoelectric chip, a microelectrode array and a common electrode fixed on the lower side surface and upper side surface of the piezoelectric chip, respectively, and a BSE PrP antibody array to constitute the piezoelectric biochip for the detection of the BSE pathogen. The BSE PrP antibodies are immobilized on the electrodes of the microelectrode array in a format corresponding uniquely to the electrodes of the microelectrode array by adsorbing, bonding, cross-linking, embedding or self-assembly process. The combination of the piezoelectric biochip and a detector constitutes the piezoelectric biochip detection system for the BSE pathogen.

Abstract: The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here signalin-related genes, which are involved in signal transduction induced by members of the TGF? superfamily. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.

Abstract: A switching-mode power converter includes input and output circuits. A transformer having primary and secondary windings which are respectively coupled to the input and output circuits. The secondary winding has two end terminals respectively connected to first and second switches. The first and second switches are also joined together at a common node. The secondary winding also has a mid terminal. A filter circuit is disposed between the mid terminal and the common node. The first and second switches are controlled by complementary control circuits which selectively allow current to orderly pass through the filter circuit via the switches during the forward rectification, resetting, and freewheeling modes of operation of the power converter.

Abstract: A switching-mode power converter includes input and output circuits. A transformer having primary and secondary windings which are respectively coupled to the input and output circuits. The secondary winding has two end terminals respectively connected to first and second switches. The first and second switches are also joined together at a common node. The secondary winding also has a mid terminal. A filter circuit is disposed between the mid terminal and the common node. The first and second switches are controlled by complementary control circuits which selectively allow current to orderly pass through the filter circuit via the switches during the forward rectification, resetting, and freewheeling modes of operation of the power converter.

Abstract: A power converter includes a transformer disposed between an input circuit and an output circuit. The transformer has primary and secondary windings coupled to the input and output circuit, respectively. Current passing through the input circuit is sensed and fed to a RC (Resistance-Capacitance) circuit which generates a signal proportional in magnitude to the output current sourcing out of the output circuit.

Abstract: A glass substrate a vanadium dioxide-based switchable film and a visible-light anti-reflection film. The vanadium dioxide-based switchable film and said visible-light anti-reflection film are coated on to the glass substrate. The vanadium dioxide-based switchable film has a switching temperature set approximately at a proper temperature or a target air-conditioning temperature to be controlled in an interior space in contact with said glass, thereby providing a solar switching and heat-insulating functions to said glass.

Abstract: It is shown here that hedgehog proteins possess novel activities beyond phenotype specification. Using cultures derived from the embryonic day 14.5 (E14.5) rat ventral mesencephalon, we show that hedgehog is also trophic for dopaminergic neurons. Interestingly, hedgehog not only promotes dopaminergic neuron survival, but also promotes the survival of midbrain GABA-immunoreactive (GABA-ir) neurons.

Abstract: The present invention provides a multifunctional high-performance automatic chromogenic window coating material in which a vanadium dioxide based thermochromic material is coated by sputtering or the like onto a transparent substrate such as a piece of window glass, and a titanium dioxide based photocatalytic material that also acts as an antireflection film is coated thereon as an outermost layer.