Abstract: A downlight includes: an outer cover; a heatsink; and a light engine located between the outer cover and the heatsink, wherein the light engine is at least partially spherical; the heatsink has a hemispherical inner surface that matches with the spherical portion of the light engine; the outer cover and the heatsink are assembled together by an elastic extension member, thereby making the hemispherical inner surface of the heatsink in contact with the spherical portion of the light engine; the downlight includes a pin provided near the elastic extension member, with one end of the pin fixed to the heatsink and the other end extending through the outer cover. Pressing the end of the pin that extends through the outer cover, the elastic extension member is further extended to separate the heatsink and the light engine so that the illumination angle of the light engine can be adjusted.

Abstract: This disclosure concerns the discovery of (R,R)- and (R,S)-fenoterol analogues which are highly effective at binding ?2-adrenergic receptors. Exemplary chemical structures for these analogues are provided. Also provided are pharmaceutical compositions including the disclosed (R,R)-fenoterol and fenoterol analogues, and methods of using such compounds and compositions for the treatment of cardiac disorders such as congestive heart failure and pulmonary disorders such as asthma or chronic obstructive pulmonary disease.

Abstract: A method for making a cooling body for a lighting device may include: a) Providing multiple aluminum nitride ceramic radiators; b) Putting the multiple aluminum nitride ceramic radiators into a mold; c) Closing the mold, and injecting a melting metal into the mold so that the metal encloses a portion of each of the aluminum nitride ceramic radiators, wherein the metal has a melting point lower than that of the aluminum nitride ceramic radiators; and d) Opening the mold, and obtaining the cooling body.

Abstract: An integrated circuit for configuring and reconfiguring a configuration shift register (CSR) partial reconfiguration region is disclosed. The integrated circuit includes a CSR chain that is partitioned into a group of CSR partial reconfiguration regions. A multiplexer circuit is added to the end of each PR region to allow the PR region to be bypassed or connected to the next PR region. Each PR region is connected to a PR circuit that facilitates the CSR configuration of the respective PR region. The PR circuit includes region enable circuitry and region control circuitry. Region enable circuitry enables the configuration of the CSR PR region. Region control circuitry generates local reconfiguration control signals to control the configuration operation of the enabled CSR PR region.

Abstract: A method for synchronizing file paths associated with computer files based on file path modifications is provided. The method may include detecting a file path modification to a referenced file path associated with a computer file. The method may also include identifying a type of the file path modification. The method may further include identifying a generated file path based on the type of the file path modification. Additionally, the method may include synchronizing the referenced file path to the generated file path. The method may also include modifying the file path information associated with the computer file. The method may further include generating association information in a file properties window associated with the referenced file path and the at least one generated file path. The method may also include validating and extracting the file path information associated with the computer file for use by at least one application.

Abstract: A method for synchronizing file paths associated with computer files based on file path modifications is provided. The method may include detecting a file path modification to a referenced file path associated with a computer file. The method may also include identifying a type of the file path modification. The method may further include identifying a generated file path based on the type of the file path modification. Additionally, the method may include synchronizing the referenced file path to the generated file path. The method may also include modifying the file path information associated with the computer file. The method may further include generating association information in a file properties window associated with the referenced file path and the at least one generated file path. The method may also include validating and extracting the file path information associated with the computer file for use by at least one application.

Abstract: The disclosure provides an arrangement structure suitable for an inverted pulverized coal boiler with ultra-high steam temperature steam parameters, including a hearth, wherein the hearth is communicated with a middle uplink flue, and the top of the middle uplink flue is communicated with that of a tail downlink flue. In the structure, the hearth is connected with the middle uplink flue by a hearth outlet horizontal flue at the bottom, so that the high-temperature gas is drained to a low elevation and then flows upwards through the middle uplink flue; a final heating surface may be arranged at the low position of the hearth outlet horizontal flue and the middle uplink flue so as to reduce the length of the high-temperature steam pipeline between the final heating surface and the steam turbine, lower the manufacturing cost of the boiler as well as the frication and radiation loss of the pipe.

Abstract: A method for making a cooling body for a lighting device may include: a) Providing multiple aluminum nitride ceramic radiators; b) Putting the multiple aluminum nitride ceramic radiators into a mold; c) Closing the mold, and injecting a melting metal into the mold so that the metal encloses a portion of each of the aluminum nitride ceramic radiators, wherein the metal has a melting point lower than that of the aluminum nitride ceramic radiators; and d) Opening the mold, and obtaining the cooling body.

Abstract: An integrated circuit for configuring and reconfiguring a configuration shift register (CSR) partial reconfiguration region is disclosed. The integrated circuit includes a CSR chain that is partitioned into a group of CSR partial reconfiguration regions. A multiplexer circuit is added to the end of each PR region to allow the PR region to be bypassed or connected to the next PR region. Each PR region is connected to a PR circuit that facilitates the CSR configuration of the respective PR region. The PR circuit includes region enable circuitry and region control circuitry. Region enable circuitry enables the configuration of the CSR PR region. Region control circuitry generates local reconfiguration control signals to control the configuration operation of the enabled CSR PR region.

Abstract: A 3D field programmable gate array (FPGA) system, and method of manufacture therefor, includes: a field programmable gate array (FPGA) die having a configurable power on reset (POR) unit; a heterogeneous integrated circuit die coupled to the FPGA die; and a 3D power on reset (POR) output configured by the configurable POR unit for initializing the FPGA die and the heterogeneous integrated circuit die.

Abstract: A gasket configured to seal an opening between two surfaces including at least one corner and at least one pressure relief notch in the corner. The gasket is formed of silicone and includes several magnets that are molded into the gasket or are inserted into apertures in the gasket in a mating engagement. In one example, the gasket is cut from a sheet of silicone in a flattened state by cutting a center seam, cutting first and second outside seam corner notches, cutting first and second inside seam corner notches, cutting first and second pressure relief notches on the first and second outside seam corner notches, and cutting third and fourth pressure relief notches on the first and second inside seam corner notches. The gasket is then opened up from the flattened state into a picture frame shape, and the first and second outside seam corner notches are glued.

Abstract: A JPEG encoding process may generate entropy encoded data indexing auxiliary information. With the assistance of such auxiliary information, a quick JPEG decoder is implemented to significantly improve the performance of processing large sized JPEG images on the mobile systems with limited computation power.

Abstract: This disclosure concerns the discovery of (R,R)- and (R,S)-fenoterol analogues which are highly effective at binding ?2-adrenergic receptors. Exemplary chemical structures for these analogues are provided. Also provided are pharmaceutical compositions including the disclosed (R,R)-fenoterol and fenoterol analogues, and methods of using such compounds and compositions for the treatment of cardiac disorders such as congestive heart failure and pulmonary disorders such as asthma or chronic obstructive pulmonary disease.

Abstract: The present disclosure provides a method for recombinant production of human sRAGE in mammalian cells, as well as a human sRAGE having a mammalian post-translational modification and compositions thereof. The present disclosure also provides a method of treating a vascular disease, injury, or inflammation in a mammal by administering to a mammal with a vascular disease, injury, or inflammation a composition comprising human sRAGE having a mammalian post-translational modification, thereby treating the vascular disease, injury, or inflammation in the mammal.

Abstract: Methods and systems for detection and monitoring of power supply voltage and voltage reference circuitry are provided. In one embodiment of the invention, a first signal is set to be proportional to a power supply voltage in response to a determination from control circuitry that an output voltage of bandgap voltage reference circuitry is less than a first threshold voltage. The first signal is set to a logic low level in response to a determination from control circuitry that the output voltage of the bandgap voltage reference circuit is greater than the first threshold voltage, wherein the first threshold voltage is less than a bandgap reference voltage. A value of a reset signal is determined based at least in part on the first signal.

Abstract: An encoder is provided for converting thermometer code data with bubbles to binary format. An integrated circuit may have circuitry such as digital phase-locked loop circuitry. A thermometer code data word may be used as a control signal for the circuitry. It may be desirable to monitor the thermometer code data word for testing or for downstream processing by control logic on the integrated circuit. The encoder performs thermometer code to binary encoding without requiring that the thermometer code be error corrected to remove bubbles. A bubble detection circuit may be used to detect when the thermometer code data contains bubbles. The encoder may use carry look-ahead adders and pipeline stages.

Abstract: The present disclosure provides a method for recombinant production of human sRAGE in mammalian cells, as well as a human sRAGE having a mammalian post-translational modification and compositions thereof. The present disclosure also provides a method of treating a vascular disease, injury, or inflammation in a mammal by administering to a mammal with a vascular disease, injury, or inflammation a composition comprising human sRAGE having a mammalian post-translational modification, thereby treating the vascular disease, injury, or inflammation in the mammal.

Abstract: Disclosed are a method of determining an HPV integration site in a genome of a human tissue sample and a system thereof. The method comprises: subjecting genome DNA of the human tissue sample to a first sequencing, to obtain a sequencing result; determining DNA fragments containing both HPV sequence and human genome sequence, based on the sequencing result; determining a pair of amplification primers based on the DNA fragments containing both HPV sequence and human genome sequence, subjecting the genome DNA of the human tissue sample to PCR amplification using the pair of amplification primers, to obtain PCR product; and subjecting the PCR product to a second sequencing, to determine the integration site in a genome of the human tissue sample. The method is easy to be operated with low cost, high efficiency and excellent repeatability, which may be used to detect all HPV genotypes one time, and may rapidly and accurately determine detailed sequence information and integration site.

Abstract: The disclosure provides an M-type pulverized coal boiler suitable for ultrahigh steam temperature. The pulverized coal boiler comprises a hearth of which the bottom is provided with a slag hole and a tail downward flue of which the lower part is provided with a flue gas outlet. The pulverized coal boiler further comprises a middle flue communicated between the hearth and the tail downward flue, wherein the middle flue comprises an upward flue and a hearth outlet downward flue of which the bottoms are mutually communicated and the upper ends are respectively communicated with the upper end of the hearth and the upper end of the tail downward flue to form a U-shaped circulation channel.

Abstract: This disclosure concerns the discovery of (R,R)- and (R,S)-fenoterol analogues which are highly effective at binding ?2-adrenergic receptors. Exemplary chemical structures for these analogues are provided. Also provided are pharmaceutical compositions including the disclosed (R,R)-fenoterol and fenoterol analogues, and methods of using such compounds and compositions for the treatment of cardiac disorders such as congestive heart failure and pulmonary disorders such as asthma or chronic obstructive pulmonary disease.