Abstract: The disclosure provides a construction method including steps of: constructing a detailed model and a simplified model of the rail vehicle using finite element method based on the three-dimensional structure of the rail vehicle; initially setting the simplified model in accordance with the detailed model, including specifying materials, mechanical properties parameters, and mass point; setting different simplification thickness ratio to obtain a plurality of sets of the simplified models, designing longitudinal and lateral collision conditions, and in each type of the collision conditions, performing collision simulations on the detailed model and each set of the simplified models under each thickness ratio to obtain respective collision response curves; calculating a total CORA value corresponding to the plurality of sets of the simplified models; selecting an optimal simplified model from n sets of the simplified models with the highest total CORA values.

Abstract: Provided are a vehicle monitoring method and a vehicle monitoring system. The vehicle monitoring method includes that: a polarization angle of polarized light in a sky image reflected by a vehicle window in a monitoring scenario is calculated, and a light-filtering polarization angle is calculated according to the polarization angle of the polarized light in the sky image reflected by the vehicle window, where the polarized light in the sky image is formed by scattered sunlight in a sky region corresponding to the sky image; the polarized light in the sky image reflected by the vehicle window in the monitoring scenario is filtered out according to the light-filtering polarization angle; and the monitoring scenario is imaged to form a monitoring image.

Abstract: The present invention proposes an apparatus (120) and method for detecting bone fracture of a subject on basis of ultrasound images. The apparatus (120) comprises a first fracture detector (122) and a second fracture detector (124). The first fracture detector (122) is configured to receive a first ultrasound image of a region of the subject, to identify a bone in the first ultrasound image, to identify at least one focus area within the region on basis of the identified bone, to generate focus area information indicating position of the at least one focus area, and to instruct an acquisition of a second ultrasound image of the region acquired based on the generated focus area information. The second fracture detector (124) is configured to receive the second ultrasound image, and to detect bone fracture on the basis of the second ultrasound image.

Abstract: According to an aspect, there is provided an apparatus for use in processing image data relating to a subject, the apparatus comprising a memory comprising instruction data representing a set of instructions; and a processor configured to communicate with the memory and to execute the set of instructions, wherein the set of instructions, when executed by the processor, cause the processor to: responsive to receiving input indicating a point in an image corresponding to an anatomical feature or sub-feature, determine if sufficient points to perform a measurement have been received based on a comparison of anatomical features and/or sub-features corresponding to the indicated point and any other indicated points with prestored anatomical data, the pre-stored anatomical data indicating for at least one measurement the anatomical features and/or sub-features required to perform the at least one measurement; and if sufficient points to perform a measurement have been received, perform the measurement.

Abstract: The present invention discloses a bacterium and an obtaining method and application thereof. The bacterium has a property of coproducing 1,3-propanediol and D-lactic acid. Further, the bacterium is Klebsiella oxytoca, including Klebsiella oxytoca PDL-5 CCTCC M 2016185. The obtaining method of the bacterium may be to obtain the bacterium by directly screening wild bacteria that satisfy conditions from the environment or performing gene engineering modification to wild bacteria. The present invention has the advantages that the bacteria can coproduce 1,3-propanediol and D-lactic acid through fermentation, the molar conversion rate and the concentration of the two products are very high, the types of byproducts are few, the concentration is low, the product extraction process is simplified, the high-efficiency biological production of 1,3-propanediol and D-lactic acid can be realized, and the industrial application prospect is very great.

Abstract: Systems, devices, and methods are provided to provide serial monitoring for a patient. An ultrasound system is provided which may include subdividing a portion of the anatomy of a patient into a number of zones. Imaging data may be received by an imaging device. This imaging data may be used to generate a severity score for each zone based on imaging parameters within the imaging data. Changes in the severity score for each zone may be displayed over time, such that a medical professional may monitor each zone in a serial manner.

Abstract: Provided are a genetically engineered strain for producing polylactic acid and a method for producing polylactic acid. The genome of the genetically engineered strain is integrated with a coding sequence of exogenous D-lactate dehydrogenase gene, a coding sequence of exogenous propionyl-CoA transferase gene, and a coding sequence of exogenous polyhydroxyalkanoate synthase gene, enabling the genetically engineered strain to express exogenous D-lactate dehydrogenase, exogenous propionyl-CoA transferase, and exogenous polyhydroxyalkanoate synthase. The method includes: providing the above genetically engineered strain of Synechococcus elongatus; introducing carbon dioxide and culturing the genetically engineered strain under light; and when a growth OD of the genetically engineered strain reaches the maximum, collecting and drying the genetically engineered strain, and recycling the polylactic acid in the strain.

Abstract: A double-channel fluid injection apparatus includes a main shaft, a bearing box, and a sealing box. The main shaft includes an outer tube and an inner tube. An internal channel of the inner tube and a vertical through channel constitute a first fluid passageway. The inner tube and the outer tube form an annular gap, and a channel D is radially formed at a lower part of the outer tube and is in communication with the annular gap, thus constituting a second fluid passageway. The bearing box is mounted on a boss of the outer tube. The sealing box includes a sealing cylinder fixedly connected to a lower end of a lower end cap of the bearing box. A channel E in communication with the second fluid passageway is radially formed at a position of the sealing cylinder corresponding to the channel of the outer tube.

Abstract: A startup stage protection device used in Electric Multiple Unit (EMU) train coupler experiment is provided between two test cars. The startup stage protection device is arranged between and tightly abuts two test cars at the starting stage of the experiment to receive a compressing force in place of the coupler. The startup stage protection device separates from the two test cars after the end of the starting stage.

Abstract: An ultrasound imaging system may acquire an image of a liver. The liver may be segmented from the image. Parameters, such as image homogeneity map, intensity probability chart, and/or speckle size diagram, may be extracted from the liver portion of the image. The parameters may be used to determine whether fatty liver deposits are diffuse or inhomogeneous. In some examples, inhomogeneous regions may be excluded from the calculation of liver fat quantification measurements. In some examples, the inhomogeneous regions may be displayed so that a user may select a region of interest that excludes the inhomogeneous regions to calculate the liver fat quantification measurements.

Abstract: The present invention discloses a bacterium and an obtaining method and application thereof. The bacterium has a property of coproducing 1,3-propanediol and D-lactic acid. Further, the bacterium is Klebsiella oxytoca, including Klebsiella oxytoca PDL-5 CCTCC M 2016185. The obtaining method of the bacterium may be to obtain the bacterium by directly screening wild bacteria that satisfy conditions from the environment or performing gene engineering modification to wild bacteria. The present invention has the advantages that the bacteria can coproduce 1,3-propanediol and D-lactic acid through fermentation, the molar conversion rate and the concentration of the two products are very high, the types of byproducts are few, the concentration is low, the product extraction process is simplified, the high-efficiency biological production of 1,3-propanediol and D-lactic acid can be realized, and the industrial application prospect is very great.

Abstract: A transcriptional regulator specifically responding to D-2-hydroxyglutarate (D-2-HG) and its application in the biological detection of D-2-HG. Wherein the transcriptional regulator is named DhdR and the nucleotide sequence is shown as SEQ ID NO: 1. The D-2-HG biosensors BD2HG-0 and BD2HG-1 are constructed using the transcriptional regulator DhdR and can detect biological samples containing D-2-HG.

Abstract: The present invention discloses a method for calibrating controllable phase shifters in a multi-stage staggered Mach-Zehnder interferometer structure on an optical chip, aiming to solve the problem of calibrating the controllable phase shifters in a configurable optical network of the multi-stage staggered Mach-Zehnder interferometers. The technical solution is to calibrate the controllable phase shifters that can be calibrated in the optical network; and then to constitute calibration conditions for and calibrate inner phase shifters that has not been; and finally to constitute calibration conditions for and calibrate outer phase shifters that is not calibrated.

Abstract: A filter having antibacterial activity is provided. The filter comprises at least one layer of polymer nanofibers and antibacterial particles positioned on or within the at least one layer of polymer nanofibers, wherein the antibacterial particles comprise a quaternary ammonium compound grafted onto a surface of a metal-organic framework. Methods of manufacturing the filter and decontaminating a fluid are also provided.

Abstract: A point-of-interest (POI) information management method includes: obtaining a webpage link; obtaining a webpage text associated with the webpage link; obtaining at least one item of POI information matching the webpage text from a POI information repository; presenting the at least one item of the POI information; in response to a pre-determined operation being performed on a first item of the POI information of the at least one item of the POI information, presenting a route from a current location to an address indicated in the first item of the POI information and a first operable icon; and in response to detecting another pre-determined operation is performed on the first operable icon, setting the route as a target trip.

Abstract: A genetically engineered bacterial strain that produces N-acetylglucosamine, as well as a method of construction and use thereof. The genetically engineered bacterial strain can ferment N-acetylglucosamine under a condition of 40-50° C. Through knocking out genes for glucosamine 6-phosphate deaminase, N-acetylglucosamine-6-phosphate deacetylase and the N-acetylglucosamine transporter protein from a parental bacterium, an N-acetylglucosamine catabolism pathway is blocked. Moreover, overexpression genes for glucosamine 6-phosphate synthase and glucosamine 6-phosphate acetylase are introduced, enabling extra cellular accumulation of N-acetylglucosamine and high-temperature fermentation of N-acetylglucosamine at a temperature higher than 40° C.

Abstract: In a method for making a measurement of the hip in an ultrasound image, an ultrasound image of the hip is obtained. A spatial coherence map associated with one or more lags of the ultrasound waves associated with the ultrasound image is also obtained. Then a quality metric is determined based on the ultrasound image of the hip and the spatial coherence map. The quality metric indicates the suitability of the ultrasound image for making the measurement of the hip. If the quality metric indicates that the ultrasound image is above a threshold quality, then the method then comprises indicating that the ultrasound image is suitable for making the measurement of the hip.

Abstract: A motor vehicle lock comprising a locking mechanism which essentially consists of a rotary latch and a pawl, further comprising a drive and a securing element. The drive acts on the securing element via a toothed rack element that is equipped with a blocking element. According to the invention, the blocking element is in the form of a tilting lever defining at least two end positions of the toothed rack element.

Abstract: Provided are a vehicle monitoring method and a vehicle monitoring system. The vehicle monitoring method includes that: a polarization angle of polarized light in a sky image reflected by a vehicle window in a monitoring scenario is calculated, and a light-filtering polarization angle is calculated according to the polarization angle of the polarized light in the sky image reflected by the vehicle window, where the polarized light in the sky image is formed by scattered sunlight in a sky region corresponding to the sky image; the polarized light in the sky image reflected by the vehicle window in the monitoring scenario is filtered out according to the light-filtering polarization angle; and the monitoring scenario is imaged to form a monitoring image.

Abstract: The present invention provides inhibitors of fucosylation during protein expression from mammalian cells. The inhibitors are derived from rhamnose and act by inhibition of GDP-mannose 4,6-dehydratase (GMD). The invention further provides methods of making proteins with reduced level of fucosylation, such as antibodies and antibodies made by the methods of the present invention. Such hypofucosylated or nonfucosylated antibodies may find use, for example, in treatment of human disease in which is it therapeutically eneficial to direct antibody dependent cellular cytotoxicity (ADCC) mediated killing of cells expressing the antibody target on their surface, for example in depletion of Tregs in cancer patients using a hypofucosylated or nonfucosylated anti-CTLA-4 antibody.