Abstract: The present invention relates to a solid form of a compound of Formula (I), a method for preparing the solid form, a pharmaceutical composition comprising the solid form, and use of the solid form in the treatment of Janus kinase (JAK) related diseases comprising, for example, inflammatory diseases, autoimmune diseases, and cancers.

Abstract: Polyurethane foams are made by curing a reaction mixture that contains an aromatic polyisocyanate, at least one isocyanate-reactive material having an average functionality of at least 2 and an equivalent weight of at least 200 per isocyanate-reactive group, at least one blowing agent, at least one surfactant and at least one catalyst, at least one cyclic 1,3-diketone compound and optionally least one antioxidant. Foams so produced emit low levels of both formaldehyde and acetaldehyde.

Abstract: A ratchet wrench includes a body, a ratchet wheel, a pawl, a ring, a top clip and a bottom clip. The body includes a through hole which defines through the top and the bottom of the body. A top recessed area and a bottom recessed area are respectively defined in the top and the bottom of the body. A recess is defined in the inner periphery of the through hole and a protrusion with a receiving slot extends from one end of the recess. A resilient member is received in the receiving slot to bias the pawl in the recess to engage with the ratchet wheel. The ring is engaged with the top recessed area. The top clip is engaged with the top recessed area and clips the ratchet wheel. The bottom clip is engaged with the bottom recessed area and clips the ratchet wheel.

Abstract: Pattern centric process control is disclosed. A layout of a semiconductor chip is decomposed into a plurality of intended circuit layout patterns. For the plurality of intended circuit layout patterns, a corresponding plurality of sets of fabrication risk assessments corresponding to respective ones of a plurality of sources is determined. Determining a set of fabrication risk assessments for an intended circuit layout pattern comprises determining fabrication risk assessments based at least in part on: simulation of the intended circuit layout pattern, statistical analysis of the intended circuit layout pattern, and evaluation of empirical data associated with a printed circuit layout pattern. A scoring formula is applied based at least in part on the sets of fabrication risk assessments to obtain a plurality of overall fabrication risk assessments for respective ones of the plurality of intended circuit layout patterns.

Abstract: The present disclosure provides a touch display panel, a flexible display panel and a display apparatus. In one embodiment, light sensitive effect-based photo-sensitive diodes and switching transistors for controlling signal output of the photo-sensitive diodes are integrated in the display panel. Once a touch operation of an object (e.g., a finger) is implemented on a surface of the display panel, the photo-sensitive diode in a corresponding position can convert a sensed light intensity difference into an electrical signal difference to achieve detection of the touch operation.

Abstract: An array electromagnetic tool is run in a borehole, and resulting signals are processed to provide at least one of real and imaginary conductivity components, ?R* and ?I*. The at least one of real and imaginary conductivity components is compared to a corresponding representative conductivity component of a plurality of different clay groups and a determination of clay type in the formation is made therefrom.

Abstract: A fixture for display module inspection is disclosed. The fixture includes a base, a lower rotatable body pivotally mounted on the base, a middle rotatable body hinged with the lower rotatable body, an upper rotatable body hinged with the middle rotatable body and a carrier fixedly connected to the upper rotatable body for carrying a display module. A rotation axis of the lower rotatable body and a rotation axis of the middle rotatable body are arranged orthogonally to each other, the rotation axis of the middle rotatable body and a rotation axis of the upper rotatable body are arranged orthogonally to each other. Rotation position locking mechanisms are respectively provided between the lower rotatable body and the base, between the middle rotatable body and the lower rotatable body, and between the upper rotatable body and the middle rotatable body.

Abstract: A method for drilling includes obtaining formation-measurement pairings, training a machine-learning model using the formation-measurement pairings, receiving measurements obtained by a tool positioned in a well formed in a formation, and generating a formation model of at least a portion of the formation using the machine-learning model and the measurements. The formation model represents one or more physical parameters of the formation, one or more structural parameters of the formation, or both.

Abstract: Embodiments of the present systems and methods may provide techniques for systematic drug repositioning that fully leverages drug-drug interactions. In embodiments, the present systems and methods may generate a drug similarity metric based on DDI data and make drug repositioning predictions by leveraging the new similarity metric. For example, in an embodiment, a computer-implemented method for conducting a drug repositioning trial may comprise receiving data relating to drug-drug interactions, generating drug interaction vectors for each drug in the received data, generating a logistic regression model to generate drug repositioning hypotheses, generating at least one drug repositioning hypothesis using the logistic regression model, and conducting a drug repositioning trial using the generated drug repositioning hypothesis.

Abstract: A method and apparatus for performing a search in a processor-in-memory (PIM) system having a first processor and at least one memory module includes receiving one or more images by the first processor. The first processor sends a query for a search of memory for a matching image to the one or more images to at least one memory module, which searches memory in the memory module, in response to the received query. The at least one memory module sends the results of the search to the first processor, and the first processor performs a comparison of the received results from the at least one memory module to the received one or more images.

Abstract: Techniques are described that facilitate determining potential cancer gene therapy targets by joint modeling of cancer survival events. In one embodiment, a computer-implemented comprises employing, by a device operatively coupled to a processor, a multi-task learning model to determine active genetic factors respectively associated with different types of cancer based on cancer survival data and patient genomic data for groups of patients that respectively survived the different types of cancer. The computer-implemented method further comprises, determining, by the device, common active genetic factors of the active genetic factors that are shared between two or more types of cancer of the different types of cancer.

Abstract: Polyurethane foams are made by curing a reaction mixture that contains an aromatic polyisocyanate, at least one isocyanate-reactive material having an average functionality of at least 2 and an equivalent weight of at least 200 per isocyanate-reactive group, at least one blowing agent, at least one surfactant and at least one catalyst, at least one polyacetoacetate compound and least one antioxidant. Foams so produced emit low levels of both formaldehyde and acetaldehyde.

Abstract: The present disclosure provides a microfluidic device, a driving method thereof and a microfluidic system. The microfluidic device includes a first substrate and a second substrate disposed opposite to each other, and a microcavity provided between the first and second substrates for accommodating droplets. The microfluidic device further includes at least one ultrasonic layer provided between the first and second substrates. The at least one ultrasonic layer includes a plurality of ultrasonic sensors configured to perform at least one of detection operation and driving operation to the droplets accommodated in the microcavity.

Abstract: An energy-storing-type high-pressure electric fuel pump includes an electromagnetic driving apparatus and a plunger sleeve cylinder component. The plunger sleeve cylinder component includes a high-pressure volume, a plunger sleeve having a plunger hole, and a plunger capable of sliding within the plunger hole. A clearance volume of the plunger in the plunger hole is a high-pressure fuel chamber. A clearance volume between the electromagnetic driving apparatus and the plunger sleeve cylinder component forms a low-pressure fuel chamber. Under the action of the electromagnetic driving apparatus, the plunger sleeve cylinder component sucks a fuel in the low-pressure fuel chamber into the high-pressure fuel chamber and pressure-feeds the fuel into the high-pressure volume. The electromagnetic driving apparatus includes an energy storage apparatus, a movable part, and a still part.

Abstract: A ratchet wrench includes at least one ratchet mechanism. The at least one ratchet mechanism comprises a body, a ratchet wheel, a pawl, a switch unit, a ring and a top clip. The body includes a through hole, a first recess, a second recess and a top recessed area to accommodate the ratchet wheel, the pawl, the switch unit, the ring and the top clip. The ratchet wheel has a first pivotal portion, a top groove, a second pivotal portion and a restricting protrusion. The switch unit is pivoted to control the movement of the pawl in the first recess. The ring is located in the top recessed area and has a fourth pivotal portion connected to the first pivotal portion. The top clip and the restricting protrusion on two ends of the ratchet wheel restrict the ring and the ratchet wheel in the through hole.

Abstract: Provided are a temperature sensor, an array substrate, and a display device. In the temperature sensor, a low-pass filter is disposed between a ring oscillator and a comparator, so that a square-wave signal output from the ring oscillator passes through the low-pass filter and a high-frequency component in the square-wave signal output from the ring oscillator is directly filtered out by the low-pass filter, thereby improving a signal-to-noise ratio of the ring oscillator and a test accuracy of the temperature sensor.

Abstract: Predicting beneficial drug combinations mitigating adverse drug reactions identifies drug combinations and associated target adverse drug reaction from a spontaneous reporting system containing case reports of drugs and associated adverse drug reactions. Each drug combination comprises a first drug and a second drug, and a propensity score is computed for each drug in each group. This propensity score expresses a probability of being exposed to a given drug based on other co-prescribed drugs and reported indications, which reflect patient characteristics. Associations are computed for each drug as well as drug interaction. Among the associations, the sum of the associations of the second drug and the interaction effect represents the predicted beneficial score expressing whether the second drug alters the chance of developing the target adverse drug reaction for patients on the first drug.

Abstract: The embodiments of the present disclosure disclose a touch panel and a display apparatus. The touch panel includes a display unit comprising a plurality of pixel units; and a fingerprint recognition sensor disposed on one side of the display unit which is opposite to a light emitting surface of the display unit, wherein the display unit further comprises at least one via hole disposed between two adjacent pixel units, and a light divergence member disposed on one side of each via hole which is close to the fingerprint recognition sensor. The light divergence member is configured to irradiate reflected light obtained as light emitted by the pixel units is reflected by a touch body onto the fingerprint recognition sensor.

Abstract: Embodiments of the present invention disclose a method, a computer program product, and a computer system for predicting drug and food interactions. A computer identifies one or more drug similarity measures between one or more drugs and one or more food similarity measures between one or more foods. In addition, the computer identifies one or more interactions between the one or more drugs and the one or more foods, then calculates one or more drug-food feature vectors based on the one or more interactions, the one or more drug similarity measures, and the one or more food similarity measures. Furthermore, the computer calculates a first probability indicating whether a first drug of the one or more drugs will interact with a first food of the one or more foods based on a model, wherein the model is trained based on the one or more drug-food feature vectors.

Abstract: A comparator offset voltage self-correction circuit is disclosed. A comparator offset voltage which is caused by the semiconductor process parameter randomness also has randomness. Due to the randomness of the comparator offset voltage, a reference voltage of a parallel comparator in a parallel-conversion-type analog-to-digital converter is uncertain. If the comparator offset voltage is large, the parallel-conversion-type analog-to-digital converter may even have a functional error. The comparator offset voltage self-correction circuit provided in the present invention can correct a random offset voltage of a comparator to meet requirements.