Abstract: Provided is a coal-containing wastewater spraying device for dust suppression during coal conveying, including a motor, a gland, a body seat, and an accelerator. The body seat includes a funnel-shaped cover, a first disc and a plurality of crushing plates. The accelerator includes a circular second disc. The end of an output shaft of the motor passes through the first disc to connect with the second disc. The cover is provided with a water retaining ring between the first disc and the second disc along its axial direction. The cover, the first disc, the second disc and the water retaining ring form a water inlet space.

Abstract: The present disclosure provides pharmaceutical combinations comprising at least one spliceosome modulator and at least one inhibitor chosen from BCL2, BCL2/BCLxL, and BCLxL inhibitors. Also provided are methods of treating cancer comprising administering a therapeutically effective amount of at least one spliceosome modulator and a therapeutically effective amount of at least one inhibitor chosen from BCL2, BCL2/BCLxL, and BCLxL inhibitors.

Abstract: The present disclosure relates to methods of treating heat shock factor 1 (HSF1)-related diseases such as cancer and viral diseases, using a therapeutically effective amount of a RNAi agent to HSF.

Abstract: Linker-drug compounds and antibody-drug conjugates that bind to human oncology targets are disclosed. The linker-drug compounds and antibody-drug conjugates comprise a splicing modulator drug moiety. The disclosure further relates to methods and compositions for use in the treatment of neoplastic disorders by administering the antibody-drug conjugates provided herein. In an embodiment, the splicing modulator comprises a pladienolide or a pladienolide derivative.

Abstract: An image processing method performed by a terminal is provided. A molybdenum target image is obtained, and a plurality of candidate regions are extracted from the molybdenum target image. In the molybdenum target image, a target region is marked in the plurality of candidate regions by using a neural network model obtained by deep learning training, a probability that a lump comprised in the target region is a target lump being greater than a first threshold, a probability that the target lump is a malignant tumor being greater than a second threshold, and the neural network model being used for indicating a mapping relationship between a candidate region and a probability that a lump comprised in the candidate region is the target lump.

Abstract: A display panel, a display device, and a method of manufacturing a display panel are provided. As an example, the display panel includes an array layer, a planarization layer, an inorganic layer, and at least one dam. The array layer includes a first region and a second region surrounding the first region. The planarization layer is at least partially located on a portion of the array layer which is at the first region. The inorganic layer is located on a portion of the array layer which is at the second region. The at least one dam is formed on the inorganic layer.

Abstract: Provided is an annular rotatable air supply device for a coal storage Eurosilo. The device includes an air duct rotatable ring and an air duct fixing ring. The air duct rotatable ring is fixedly connected with a central revolving platform of the Eurosilo by a second support bracket, the air duct fixing ring is fixedly connected with a top trestle of the Eurosilo by a first support bracket, and the air duct rotatable ring and the air duct fixing ring are arranged coaxially with the central axis of rotation of the Eurosilo. The air duct air duct rotatable ring is sealingly connected with the air duct fixing ring via a sealing assembly, and the air duct rotatable ring and the air duct fixing ring form an annular air duct therebetween.

Abstract: The present invention relates to a support device used in weighing coal of a raw coal bunker in a thermal power plant and a weighable raw coal bunker. The support device includes a base, a positioning sleeve, an upper support and a weighing sensor, a sensor groove being provided in the middle of the base, the weighing sensor being arranged in the sensor groove, the positioning sleeve being arranged on the base in a covering mode, a positioning hole being provided in the middle of the positioning sleeve, the upper support being movably inserted in the positioning hole, and a bottom surface of the upper support penetrating the positioning hole to abut against a top surface of the weighing sensor. The raw coal bunker uses the support device. Compared with the prior art, the present invention effectively meets the weighing requirement of the raw coal bunker.

Abstract: The present invention relates to a ventilating and blanking device for a coal storage Eurosilo. The ventilating and blanking device includes a top blanking pipe, an axial flow fan and a baffle door, the top blanking pipe including a first pipeline and a second pipeline, an air supply pipe is connected to a side wall of the second pipeline, and the baffle door is connected to a driving mechanism; during blanking, the driving mechanism drives the baffle door so as to make the baffle door close the air supply pipe and the axial flow fan is shut off; and during ventilation, the driving mechanism drives the baffle door so as to make the baffle door close the first pipeline, and the axial flow fan is turned on. Compared with the prior art, the present invention has the advantages of ventilation efficiency, good ventilation effect, etc.

Abstract: Provided is a micro-mist suppression device for a coal storage Eurosilo for suppressing dust within the Eurosilo, comprising a micro-mist dust suppression host and a water-gas supply module and a micro-mist generation module connected with the micro-mist dust suppression host; the water-gas supply module includes a water supply unit and an gas supply unit; the water supply unit includes an annular water tank, a variable frequency pump and a water filter which are successively connected, the micro-mist suppression host is connected with the water filter and the variable frequency pump; the gas supply unit includes an air compressor and an air reservoir, the air compressor, the air reservoir and the micro-mist dust suppression host are successively connected; the micro-mist generation module includes a first water-gas hose, a feed assembly and a water-gas distributor which are successively connected, the water-gas distributor is connected with a micro-mist spray head

Abstract: The present disclosure provides a display panel, manufacturing method thereof, and a display device. The display panel includes a substrate, a functional layer formed on the substrate, and an encapsulation layer formed on the functional layer. The encapsulation layer includes an inorganic layer on the functional layer, the inorganic layer includes a first oxide layer and a second oxide layer, and a ratio of the number of atomic layers of the first oxide layer to the number of atomic layers of the second oxide layer ranges from 1:4 to 3:1.

Abstract: A display panel, a manufacturing method thereof, and a display device. The manufacturing method includes: providing a pretreatment solution containing a water-soluble organic protective agent, and forming, on an anode, a solution layer covering the anode; drying the solution layer to form an adhesive layer; removing the adhesive layer; and drying the anode; where the pretreatment solution contains 10-30% by weight of propylene glycol methyl ether and 70-90% by weight of water.

Abstract: The present invention relates to a protection device for a belt conveyor. The protection device is arranged on a return conveyor belt, the protection device includes a rotation shaft, a foreign matter barrier plate and a rotation triggering mechanism, the rotation shaft being fixedly connected to a frame of the belt conveyor, the foreign matter barrier plate being vertically arranged, a top of the foreign matter barrier plate being fixedly connected to the rotation shaft, a bottom of the foreign matter barrier plate and the return conveyor belt being arranged at an interval, the rotation triggering mechanism being fixedly connected to the rotation shaft, and the foreign matter barrier plate driving the rotation shaft to rotate, and driving the rotation triggering mechanism to operate when the device is used.

Abstract: Linker-drug compounds and antibody-drug conjugates that bind to human oncology targets are disclosed. The linker-drug compounds and antibody-drug conjugates comprise a splicing modulator drug moiety. The disclosure further relates to methods and compositions for use in the treatment of neoplastic disorders by administering the antibody-drug conjugates provided herein. In an embodiment, the splicing modulator comprises a pladienolide or a pladienolide derivative.

Abstract: Display panel, manufacturing method thereof, and display device are provided. As an example, the display panel includes a substrate, a TFT layer formed on the substrate, and an encapsulation layer formed on the TFT layer. The TFT layer includes a thin film transistor with a source electrode, a drain electrode and a gate electrode, and further includes a first metal layer, a first inorganic layer on the first metal layer, and a second metal layer on the first inorganic layer. The second metal layer includes a first region and a second region, a hollowed-out region is formed between the first region and the second region, and the first region and the second region are electrically connected via the first metal layer. A portion of the encapsulation layer that is located in the hollowed-out region is in contact with the first inorganic layer.

Abstract: Antibodies, antigen-binding fragments, and conjugates (e.g., antibody-drug conjugates (ADCs) such as those comprising a splicing modulator) that bind to BCMA are disclosed. The disclosure further relates to methods and compositions for use in the treatment of cancer by administering a composition provided herein.

Abstract: A thin-film encapsulation structure includes a number of inorganic film layers and at least one organic film layer laminated alternately at one side of an organic light-emitting diode. The number of inorganic film layers include N inorganic film layers including first to N-th inorganic film layers arranged sequentially from inside to outside, N?2. At least the first inorganic film layer has a refractive index increasing gradually from inside to outside.

Abstract: A device for moving film-supported materials and removing the film at a process station includes a first base, a feeding tray, a driving member, a second base, a moving member, and a laser sensor. The feeding and stripping automatically conveys a raw material assembly. A gap exists between the second base and the first base, and only raw materials are passed over the gap. The raw material assembly comprises a base layer and a number of raw materials disposed on the base layer. The gap allows the raw material disposed on a bent portion of the base layer to separate from the base layer while the base layer itself is gathered to another destination.

Abstract: This disclosure relates to methods for the treatment of neoplastic disorders by administering Compound 1, or a pharmaceutically acceptably salt thereof, on its own and/or as part of a conjugate or composition, and inducing production of at least one neoantigen.

Abstract: A thin-film encapsulation structure, includes a number of inorganic film layers and at least one organic film layer laminated alternately at one side of an organic light-emitting diode. The number of inorganic film layers include N inorganic film layers including first to N-th inorganic film layers arranged sequentially from inside to outside, N?2. At least the first inorganic film layer has a refractive index increasing gradually from inside to outside.