Patents by Inventor Po-Wai Yuen

Po-Wai Yuen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ALKYNYL ALCOHOLS AND METHODS OF USE
    Publication number: 20160185797
    Abstract: The invention relates to compounds of Formula (0): wherein A1-A8, R4 and R5 each has the meaning as described herein. Compounds of Formula (0) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over-activation of NF-kB signaling is observed.
    Type: Application
    Filed: March 3, 2016
    Publication date: June 30, 2016
    Applicant: Genentech, Inc.
    Inventors: Nicole Blaquiere, Georgette Castanedo, Jianwen A. Feng, Baihua Hu, Steven Staben, Po-wai Yuen, Guosheng Wu, Xingyu Lin, Jason Burch
  • TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20160185780
    Abstract: Compounds of Formula 0, Formula I and Formula II and methods of use as Janus kinase inhibitors are described herein.
    Type: Application
    Filed: March 4, 2016
    Publication date: June 30, 2016
    Applicant: Genentech, Inc.
    Inventors: Nicholas C. RAY, Yun-Xing CHENG, Christine EDWARDS, Simon C. GOODACRE, Wei LI, Snahel PATEL, Matthew W. CARTWRIGHT, Mohammed SAJAD, Po-wai YUEN, Mark E. ZAK
  • 5-chloro-2-difluoromethoxyphenyl pyrazolopyrimidine compounds, compositions and methods of use thereof
    Patent number: 9346815
    Abstract: Compounds of Formula (00A) and methods of use as Janus kinase inhibitors are described herein.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: May 24, 2016
    Assignee: Genentech, Inc.
    Inventors: Mark Edward Zak, Nicholas Charles Ray, Simon Charles Goodacre, Rohan Mendonca, Terry Kellar, Yun-Xing Cheng, Wei Li, Po-Wai Yuen
  • ALKYNYL ALCOHOLS AND METHODS OF USE
    Publication number: 20160096850
    Abstract: The invention relates to compounds of Formula (0): wherein Q, A1-A8, R4 and R5 and each has the meaning as described herein. Compounds of Formula (0) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over-activation of NF-kB signaling is observed.
    Type: Application
    Filed: August 22, 2014
    Publication date: April 7, 2016
    Applicant: GENENTECH, INC.
    Inventors: Nicole Blaquiere, Georgette Castanedo, Jianwen A. Feng, Baihua Hu, Steven Staben, Po-wai Yuen, Guosheng Wu, Jason Burch
  • Substituted benzamides and their uses
    Patent number: 9296732
    Abstract: Provided herein are Substituted Benzamides, compositions, and method of their manufacture and use.
    Type: Grant
    Filed: April 11, 2013
    Date of Patent: March 29, 2016
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Auckland UniServices, Limited, Ruga Corporation
    Inventors: Amato Giaccia, Edwin Lai, Olga Razorenova, Denise Chan, Michael Patrick Hay, Muriel Bonnet, Connie Sun, Ray Tabibiazar, Po-wai Yuen
  • AMIDO SPIROCYCLIC AMIDE AND SULFONAMIDE DERIVATIVES
    Publication number: 20160002266
    Abstract: Provided are amido spirocyclic amide and sulfonamide compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.
    Type: Application
    Filed: March 1, 2013
    Publication date: January 7, 2016
    Applicants: GENENTECH, INC., FORMA TM, LLC
    Inventors: Kenneth W BAIR, Timm R BAUMEISTER, Peter DRAGOVICH, Xiongcai LIU, Snahel PATEL, Po-Wai YUEN, Mark ZAK, Guiling ZHAO, Yamin ZHANG, Xiaozhang ZHENG
  • 5-CHLORO-2-DIFLUOROMETHOXYPHENYL PYRAZOLOPYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20150336962
    Abstract: Compounds of Formula (00A) and methods of use as Janus kinase inhibitors are described herein.
    Type: Application
    Filed: May 22, 2015
    Publication date: November 26, 2015
    Applicant: Genentech, Inc.
    Inventors: Mark Edward Zak, Nicholas Charles Ray, Simon Charles Goodacre, Rohan Mendonca, Terry Kellar, Yun-Xing Cheng, Wei Li, Po-Wai Yuen
  • SUBSTITUTED BENZAMIDES AND THEIR USES
    Publication number: 20150329503
    Abstract: Provided herein are Substituted Benzamides, compositions, and method of their manufacture and use.
    Type: Application
    Filed: July 20, 2015
    Publication date: November 19, 2015
    Inventors: Amato Giaccia, Edwin Lai, Olga Razorenova, Denise Chan, Michael Patrick Hay, Muriel Bonnet, Connie Sun, Ray Tabibiazar, Po-wai Yuen
  • Substituted benzamides and their uses
    Patent number: 9085570
    Abstract: Provided herein are Substituted Benzamides, compositions, and method of their manufacture and use.
    Type: Grant
    Filed: October 10, 2011
    Date of Patent: July 21, 2015
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Auckland UniServices Limited, Ruga Corporation
    Inventors: Amato Giaccia, Edwin Lai, Olga Razorenova, Denise Chan, Michael Patrick Hay, Muriel Bonnet, Connie Sun, Ray Tabibiazar, Po-wai Yuen
  • PYRIDINYL AND PYRIMIDINYL SULFOXIDE AND SULFONE DERIVATIVES
    Publication number: 20150175621
    Abstract: Disclosed are certain pyridinyl and pyrimidinyl sulfoxide and sulfone compounds, pharmaceutical compositions comprising such compounds and methods of treatment using such compounds.
    Type: Application
    Filed: March 1, 2013
    Publication date: June 25, 2015
    Inventors: Kenneth W Bair, Timm R Baumeister, Peter Dragovich, Francis Gosselin, Po-Wai Yuen, Mark Zak, Xiaozhang Zheng
  • AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES
    Publication number: 20150104384
    Abstract: The present invention relates to certain amido-benzyl sulfoxide and sulfone compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.
    Type: Application
    Filed: March 1, 2013
    Publication date: April 16, 2015
    Inventors: Kenneth W. Bair, Timm R. Baumeister, Alexandre J. Buckmelter, Karl H. Clodfelter, Peter Dragovich, Francis Gosselin, Janet Gunzner-Toste, Bingsong Han, Jian Lin, Xiongcai Liu, Dominic J. Reynolds, Chase C. Smith, Zhongguo Wang, Mark Zak, Yamin Zhang, Guiling Zao, Xiaozhang Zheng, Po-Wai Yuen
  • SUBSTITUTED BENZAMIDES AND THEIR USES
    Publication number: 20150072976
    Abstract: Provided herein are Substituted Benzamides, compositions, and method of their manufacture and use.
    Type: Application
    Filed: April 11, 2013
    Publication date: March 12, 2015
    Inventors: Amato Giaccia, Edwin Lai, Olga Razorenova, Denise Chan, Michael Patrick Hay, Muriel Bonnet, Connie Sun, Ray Tabibiazar, Po-wai Yuen
  • ALKYNYL ALCOHOLS AND METHODS OF USE
    Publication number: 20150065482
    Abstract: The invention relates to compounds of Formula (0): wherein Q, A1-A8, R4 and R5 and each has the meaning as described herein. Compounds of Formula (0) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over-activation of NF-kB signaling is observed.
    Type: Application
    Filed: August 22, 2014
    Publication date: March 5, 2015
    Applicant: GENENTECH, INC.
    Inventors: Nicole Blaquiere, Georgette Castanedo, Jianwen A. Feng, Baihua Hu, Steven Staben, Po-wai Yuen, Guosheng Wu, Jason Burch
  • ALKYNYL ALCOHOLS AND METHODS OF USE
    Publication number: 20150057260
    Abstract: The invention relates to compounds of Formula (0): wherein A1-A8, R4 and R5 each has the meaning as described herein. Compounds of Formula (0) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over-activation of NF-kB signaling is observed.
    Type: Application
    Filed: August 22, 2014
    Publication date: February 26, 2015
    Applicant: Genentech, Inc.
    Inventors: Nicole Blaquiere, Georgette Castanedo, Jianwen A. Feng, Baihua Hu, Steven Staben, Po-wai Yuen, Guosheng Wu, Xingyu Lin, Jason Burch
  • NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT
    Publication number: 20140294805
    Abstract: The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes.
    Type: Application
    Filed: September 2, 2011
    Publication date: October 2, 2014
    Inventors: Kenneth W. Bair, Timm R. Baumeister, Alexandre J. Buckmelter, Karl H. Clodfelter, Peter Dragovich, Francis Gosselin, Bingsong Han, Jian Lin, Dominic J. Reynolds, Bruce Roth, Chase C. Smith, Zhongguo Wang, Po-Wai Yuen, Xiaozhang Zheng
  • Substituted Benzamides and Their Uses
    Publication number: 20140024649
    Abstract: Provided herein are Substituted Benzamides, compositions, and method of their manufacture and use.
    Type: Application
    Filed: October 10, 2011
    Publication date: January 23, 2014
    Applicants: Auckland UniServices Limited, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Amato Giaccia, Edwin Lai, Olga Razorenova, Denise Chan, Michael Patrick Hay, Muriel Bonnet, Connie Sun, Ray Tabibiazar, Po-wai Yuen
  • NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT
    Publication number: 20130273034
    Abstract: The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes.
    Type: Application
    Filed: September 2, 2011
    Publication date: October 17, 2013
    Inventors: Kenneth W. Bair, Timm R. Baumeister, Alexandre J. Buckmelter, Karl H. Clodfelter, Bingsong Han, Jian Lin, Dominic J. Reynolds, Chase C. Smith, Zhongguo Wang, Xiaozhang Zheng, Po-Wai Yuen
  • NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND THE USES THEREOF
    Publication number: 20130184313
    Abstract: The invention relates to pyridinyl nicotinic acetylcholine receptor ligands, compositions comprising an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand and methods to treat or prevent a condition, such as depression and nicotine dependence, comprising administering to an animal in need thereof an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand.
    Type: Application
    Filed: March 7, 2013
    Publication date: July 18, 2013
    Applicants: The Board of Trustees of the University of Illinois, PsychoGenics, Inc.
    Inventors: Jayaraman Chandrasekhar, Alan P. Kozikowski, Jianhua Liu, Werner Tueckmantel, Joel R. Walker, Po-wai Yuen
  • Nicotinic acetylcholine receptor ligands and the uses thereof
    Patent number: 8445684
    Abstract: The invention relates to pyridinyl nicotinic acetylcholine receptor ligands, compositions comprising an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand and methods to treat or prevent a condition, such as depression and nicotine dependence, comprising administering to an animal in need thereof an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand.
    Type: Grant
    Filed: October 13, 2009
    Date of Patent: May 21, 2013
    Assignees: PsycoGenics Inc., The Board of Trustee of the University of IL
    Inventors: Jayaraman Chandrasekhar, Alan P. Kozikowski, Jianhua Liu, Werner Tueckmantel, Joel R. Walker, Po-wai Yuen
  • NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND THE USES THEREOF
    Publication number: 20100152450
    Abstract: The invention relates to pyridinyl nicotinic acetylcholine receptor ligands, compositions comprising an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand and methods to treat or prevent a condition, such as depression and nicotine dependence, comprising administering to an animal in need thereof an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand.
    Type: Application
    Filed: October 13, 2009
    Publication date: June 17, 2010
    Applicants: PSYCHOGENICS, INC., The Board of Trustees of the University of Illinois
    Inventors: Jayaraman Chandrasekhar, Alan P. Kozikowski, Jianhua Liu, Werner Tueckmantel, Joel R. Walker, Po-wai Yuen