Abstract: Therapeutic or prophylactic compositions providing an active agent, such as an antigen or a vector that contains and expresses an antigen, encapsulated in or incorporated into a biodegradable polymeric particle are provided. The compositions can also provide an active agent that is not encapsulated in or incorporated into the biodegradable polymeric particle in order to provide an initial or prime delivery of the active agent. Particles or composites providing an active agent encapsulated by a first and second polymer are also provided, wherein polymers are distributed in a gradient from a core of the composite to a surface of the composite, and configured to provide a delayed release of the active agent by a period of 7 days to 6 months. Methods of producing composites are also provided.

Abstract: Techniques discussed herein relate to providing in-memory workflow management at an edge device (e.g., a computing device distinct from and operating remotely with respect to a data center). The edge device can operate as a computing node in a computing cluster of edge devices and implement a hosting environment (e.g., a distributed data plane). A work request can be obtained by an in-memory workflow manager of the edge device. The work request may include an intended state of a data plane resource (e.g., a computing cluster, a virtual machine, etc.). The in-memory workflow manager can determine the work request has not commenced and initialize an in-memory execution thread to execute orchestration tasks to configure a data plane of the computing cluster according to the intended state. Current state data corresponding to the configured data plane may be provided to the user device and eventually displayed.

Abstract: In an embodiment, a method for tracking a target using a millimeter-wave radar includes: receiving radar signals using the millimeter-wave radar; generating a range-Doppler map based on the received radar signals; detecting a target based on the range-Doppler map; tracking the target using a track; generating a predicted activity label based on the track, where the predicted activity label is indicative of an actual activity of the target; generating a Doppler spectrogram based on the track; generating a temporary activity label based on the Doppler spectrogram; assigning an uncertainty value to the temporary activity label, where the uncertainty value is indicative of a confidence level that the temporary activity label is an actual activity of the target; and generating a final activity label based on the uncertainty value.

Abstract: In an embodiment, a method of tracking includes predicting a predicted state, in a global coordinate space, of an object based on a state of the object; determining in local coordinates the predicted state; determining a plurality of measurements of the object, in the local coordinates, with first and/or second radar sensors; determining a matching of the predicted state and the plurality of measurements, in the local coordinates, for a matching result; and updating the state of the object based on the matching result. The first and second sensors are arranged along perpendicular lines which intersect at the origin of the global coordinate space.

Abstract: In an embodiment, a method for tracking a target includes: receiving raw data from a millimeter-wave radar, the raw data including a plurality of macro-Doppler frames, each macro-Doppler frame having N chirps, where each macro-Doppler frame stretches over a time interval having a first duration; generating micro-Doppler frames from the plurality of macro-Doppler frames, each micro-Doppler frame including L chirps from M macro-Doppler frames, where each micro-Doppler frame stretches over a time interval having a second duration that is longer than the first duration; detecting one or more moving targets based on the macro-Doppler frames; detecting one or more static targets based on the micro-Doppler frames; and tracking a first target as the target transitions from being detected based on the macro-Doppler frames to being detected based on the micro-Doppler frames.

Abstract: The present application provides furosemide analogues of the general formula Z having activity as anti-A? aggregation agents and/or as inhibitors of A? induced neuroinflammation. These compounds are useful in preventing, delaying and/or treating Alzheimer's Disease. Accordingly, the present application further provides pharmaceutical compositions and method for preventing, delaying and/or treating Alzheimer's Disease.

Abstract: A tire tread and a tire are provided, more particularly, a tire having a tread or other elastomeric component within enhanced composite material properties, including, but not limited to, modulus ratio, percent elongation at break, and/or tan delta, wherein the tire, tread or other elastomeric component comprise composites characterized by well dispersed reinforcing filler, which can be indicated by macrodispersion.

Abstract: Systems and method are provided for controlling a sensor of a vehicle. In one embodiment, a method includes: receiving depth image data from the sensor of the vehicle; computing, by a processor, an aleatoric variance value based on the depth image data; dividing, by the processor, the depth image data into grid cells; computing, by the processor, a confidence bound value for each grid cell based on the depth image data; computing, by the processor, an uncertainty value for each grid cell based on the confidence bound value of the grid cell and the aleatoric variance value; and controlling, by the processor, the sensor based on the uncertainty values.

Abstract: Methods, systems and computer program products for shared content management systems. In a content management system that supports multiple applications that operate on shared documents, multiple modules are operatively interconnected to make and present activity-based application recommendations. Techniques for making activity-based application recommendations include recording a series of interaction events from multiple users, which events correspond to a series of interactions performed by a plurality of applications over a shared content object. Constituent interaction events from the series of interactions are analyzed to determine a set of recommended applications. The set of recommended applications is presented to a user in a dynamically-populated user interface.

Abstract: A user interface is configured to present a stream of activities that arise from operation of two or more heterogeneous applications that access shared content objects of a content management system. A first application of a first type among the heterogeneous applications interoperates with a second application of a second type. Application activity records that correspond to interactions by the second application over the shared content objects are stored. Additional interactions that are raised by the first application and that pertain to a common content object are also stored. When a user requests access to a content object of the content management system, recent application activity records are selected. Some of the selected activity records are filtered out based on permissions attributes corresponding to the content object and/or based on permissions attributes corresponding to the requesting user. An application activity stream is generated based on the selected application activity records.

Abstract: In an embodiment, a method includes: obtaining depth data indicative of a time-resolved measurement of a 3-D position of a moveable target in a field-of-view of a depth sensor; and processing the depth data using an interacting multi-model (IMM) tracking algorithm, the IMM tracking algorithm providing, for each one of multiple iterations, tracking data comprising a respective estimate of the 3-D position of the moveable target, wherein the IMM tracking algorithm comprises a first model providing a first output, a second model providing a second output, and a fusion module fusing the first output and the second output to provide the tracking data, wherein the first model models a movement state of the moveable target, and wherein the second model models a rest state of the moveable target.

Abstract: Therapeutic or prophylactic compositions providing an active agent, such as an antigen or a vector that contains and expresses an antigen, encapsulated in or incorporated into a biodegradable polymeric particle are provided. The compositions can also provide an active agent that is not encapsulated in or incorporated into the biodegradable polymeric particle in order to provide an initial or prime delivery of the active agent. Particles or composites providing an active agent encapsulated by a first and second polymer are also provided, wherein polymers are distributed in a gradient from a core of the composite to a surface of the composite, and configured to provide a delayed release of the active agent by a period of 7 days to 6 months. Methods of producing composites are also provided.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for migrating from a first container runtime to a second container runtime.

Abstract: A light modulating device for modulating incident light in a given wavelength band is provided. The light modulating device may include: a first semiconductor layer; an active layer provided on the first semiconductor layer and having a multiple quantum well structure and a refractive index that is variable according to an electric field applied thereto, and a second semiconductor layer provided on the active layer and including a grating pattern in which a plurality of gratings extending in a first direction are repeatedly arranged in a second direction perpendicular to the first direction. The light modulating device may have high modulation efficiency owing to guided mode resonance by the grating pattern.

Abstract: A web conferencing system is hosted in a first computing environment and is Internet-connected with a content management system hosted in a second computing environment. Upon detection of an occurrence of a file or folder drag-and-drop event at the web conferencing system, the file or folder corresponding to the drag-and-drop event is made available to the content management system. A directory hierarchy of a file system of the content management system is generated on-the-fly. The content management system initiates operations to retrieve and store a copy of the file or folder into the director hierarchy. Access permissions corresponding to locations within the directory hierarchy where the copy of the file or folder is stored are established such that users of the web conferencing system who were not users of the content management system can access the copy of the file or folder that is stored in the content management system.

Abstract: Systems and method are provided for detecting an anomaly of a sensor of a vehicle. In one embodiment, a method includes: storing a plurality of sensor correlation groups based on vehicle dynamics; processing a subset of signals based on the sensor correlation groups to determine when an anomaly exists; processing the subset of signals based on the sensor correlation group to determine which sensor of the sensor correlation group is anomalous; and generating notification data based on the sensor of the correlation group that is anomalous.

Abstract: In an embodiment, a method for tracking targets includes: receiving data from a radar sensor of a radar; processing the received data to detect targets; identifying a first geometric feature of a first detected target at a first time step, the first detected target being associated to a first track; identifying a second geometric feature of a second detected target at a second time step; determining an error value based on the first and second geometric features; and associating the second detected target to the first track based on the error value.

Abstract: Embodiments are disclosed for perform offset editing in a digital design system. In particular, in one or more embodiments, the disclosed systems and methods comprise receiving a first input on a graphical user interface, the first input enabling an offset editing mode, displaying an offset editing tool at a first location on the graphical user interface, receiving a second input at a second location on the graphical user interface, and performing an action associated with the offset editing tool at the first location based on the second input at the second location, the second location offset from the first location.

Abstract: This disclosure describes a voice-controlled electronic device that includes a housing and a mounting component. The housing includes a translucent cover attached to a cylindrical-shaped unibody enclosure. The electronic device further includes a microphone array disposed near a first end within the housing, a speaker box disposed within the housing, and a printed circuit board assembly disposed within the housing. Additionally, the electronic device includes a camera disposed within the housing and attached to the printed circuit board assembly, and a depth sensor that includes a depth camera and a projector. In some instances, the camera and the depth sensor point substantially in a direction of the translucent cover. Furthermore, the electronic device includes a light ring that protrudes from a surface of the translucent display and surrounds a lens of the camera.

Abstract: In an embodiment, a method for tracking human targets includes: receiving radar signals using a radar sensor; generating a range-Doppler map based on the received radar signals; detecting a human target based on the range-Doppler map, where detecting the human target includes determining a range and a bounding box dimension of a bounding box bounding the detected human target, the bounding box at least partially surrounding the detected human target; and when the determined range is inside an expected region associated to a track, adding to the track a new detection point including the determined range and bounding box dimension, where the expected region is determined based on bounding box dimensions of detection points of the track.