Abstract: The disclosure generally relates to tamper-resistant transdermal dosage forms. The dosage forms can comprise an active agent and more than one antagonist reservoir.

Abstract: A damper system for a vehicle is provided that includes a pressure tube and a piston assembly separating the pressure tube into first and second working chambers. A frequency dependent damper assembly, coupled to a piston rod at a position below the piston assembly, includes a plunger sleeve that is longitudinally moveable to transmit an adaptive force to a first valve assembly mounted to the piston assembly. The frequency dependent damper assembly includes first and second accumulation chambers that are separated by a floating piston. A second valve assembly, carried on the floating piston, controls fluid flow between the second accumulation chamber and the second working chamber. A bleed channel in the floating piston allows fluid flow between the first and second accumulation chambers, which reduces the adaptive force the plunger sleeve applies to the first valve assembly during high frequency, low velocity rebound inputs.

Abstract: A damper system for a vehicle is provided that includes including a pressure tube, a piston rod, and a piston assembly that is mounted to the piston rod and separates the pressure tube into first and second working chambers. A valve assembly, mounted to the piston assembly, controls fluid flow between the first and second working chambers. A frequency dependent damper assembly, coupled to the piston rod at a position below the piston assembly, includes a plunger sleeve that is longitudinally moveable to transmit an adaptive force to a valve assembly. A plunger travel limiter, positioned longitudinally between the frequency dependent damper assembly and the valve assembly, contacts the plunger sleeve and prevents the plunger sleeve from moving further towards the piston assembly to limit the magnitude of the adaptive force applied to the valve assembly.

Abstract: The disclosure generally relates to tamper-resistant transdermal dosage forms. The dosage forms can comprise an active agent and more than one antagonist reservoir.

Abstract: An apparatus and methods to reduce current transient during power mode transfer in uninterruptible power supply (UPS). The disclosure provides a zero-cross detection based phase width modulated (PWM) element (E3). The element (E3) is configured to delay activation of a PWM modulator, by delaying a PWM start command for a first delay time (Tdz), wherein the first delay time is the time between receiving a static switch command to the time when a positive sequence component of a phase load current crosses zero. The element (E3) is further configured to delay the activation of the PWM modulator for a second delay time (Tdi) after the end of the first delay time (Tdz), by delaying the PWM start command for the second delay time, wherein the second delay time is based on a power factor of load connected to the UPS.

Abstract: Described are transdermal drug delivery systems for the transdermal administration of levonorgestrel and ethinyl estradiol, comprising an acrylic polymer matrix. Methods of making and using such systems also are described.

Abstract: A sampler apparatus is disclosed. The sampler apparatus comprises an impactor assembly comprising a nozzle plate, an impaction plate, and a filter unit. The nozzle plate comprises a plurality of nozzles for channelling an air stream through the sampler apparatus. The impaction plate is adapted to collect particulate matter having size equal to or greater than a threshold size. The filter unit is adapted to collect particulate matter having size less than or equal to the threshold size. The sampler apparatus further comprises a control assembly coupled with the impactor assembly. The control assembly comprises one or more flow control devices to maintain a predetermined air-flow rate of the air stream within the sampler apparatus.

Abstract: In one general aspect, a computing device includes a lid, and a base coupled to the lid by a hinge, the hinge including a bi-stable hinge part including a toggle pivot and a toggle link bar, and a barrel hinge part including a hollow shaft, at least one friction element surrounding a first portion of the hollow shaft, and a casing surrounding a second portion of the hollow shaft, the casing being connected to the toggle link bar. The computing device includes a first mounting tab connected to the toggle link bar and connected to the base, and a second mounting tab connected to the at least one friction element and connected to the lid. The barrel hinge part enables the at least one friction element to rotate about the hollow shaft causing the lid to rotate relative to the base.

Abstract: Described are transdermal drug delivery compositions comprising amphetamine, methods of making transdermal drug delivery compositions comprising amphetamine, and therapeutic methods of using them. In specific embodiments, the compositions are free of components with moieties that are reactive with amphetamine. In specific embodiments, the compositions are manufactured using solvents free of components with moieties that are reactive with amphetamine. Therapeutic methods using the compositions also are described.

Abstract: In one general aspect, a method of coupling a base to a lid of a computing device using a hinge can include coupling a base hinge flange to the base, the base hinge flange being connected to a base hinge part that includes a knuckle including a toggle pivot, the toggle pivot coupled to and surrounding a first portion of a first shaft, and coupling a lid hinge flange to the lid, the lid hinge flange being connected to a main hinge part that includes a first cam, the lid hinge flange including a first lid main band and a second lid main band surrounding a first portion of a second shaft, the second shaft being parallel to the first shaft.

Abstract: The disclosure generally relates to tamper-resistant transdermal dosage forms. The dosage forms can comprise an active agent and more than one antagonist reservoir.

Abstract: In one general aspect, an apparatus can include a base component including a keyed mount receptacle, and a power component including a keyed mount configured to be inserted into the keyed mount receptacle. The power component can be configured to be lockably coupled to the base component when the power component is rotated with respect to the base component.

Abstract: In one general aspect, a computing device includes a lid, and a base coupled to the lid by a hinge, the hinge including a bi-stable hinge part including a toggle pivot and a toggle link bar, and a barrel hinge part including a hollow shaft, at least one friction element surrounding a first portion of the hollow shaft, and a casing surrounding a second portion of the hollow shaft, the casing being connected to the toggle link bar. The computing device includes a first mounting tab connected to the toggle link bar and connected to the base, and a second mounting tab connected to the at least one friction element and connected to the lid. The barrel hinge part enables the at least one friction element to rotate about the hollow shaft causing the lid to rotate relative to the base.

Abstract: Described are transdermal drug delivery systems for the transdermal administration of levonorgestrel and ethinyl estradiol, comprising an acrylic polymer matrix. Methods of making and using such systems also are described.

Abstract: In one general aspect, a method of coupling a base to a lid of a computing device using a hinge can include coupling a base hinge flange to the base, the base hinge flange being connected to a base hinge part that includes a knuckle including a toggle pivot, the toggle pivot coupled to and surrounding a first portion of a first shaft, and coupling a lid hinge flange to the lid, the lid hinge flange being connected to a main hinge part that includes a first cam, the lid hinge flange including a first lid main band and a second lid main band surrounding a first portion of a second shaft, the second shaft being parallel to the first shaft.

Abstract: Described are transdermal drug delivery systems for the transdermal administration of levonorgestrel and ethinyl estradiol, comprising an acrylic polymer matrix. Methods of making and using such systems also are described.

Abstract: In one general aspect, an apparatus can include a base component including a keyed mount receptacle, and a power component including a keyed mount configured to be inserted into the keyed mount receptacle. The power component can be configured to be lockably coupled to the base component when the power component is rotated with respect to the base component.

Abstract: Described are transdermal drug delivery compositions comprising amphetamine, methods of making transdermal drug delivery compositions comprising amphetamine, and therapeutic methods of using them. In specific embodiments, the compositions are free of components with moieties that are reactive with amphetamine. In specific embodiments, the compositions are manufactured using solvents free of components with moieties that are reactive with amphetamine. Therapeutic methods using the compositions also are described.

Abstract: Described are transdermal drug delivery systems for the transdermal administration of levonorgestrel and ethinyl estradiol, comprising an acrylic polymer matrix. Methods of making and using such systems also are described.

Abstract: This invention relates to waterbone coating compositions having improved compatability with metal pigments, i.e., improved shelf life and reduced gassing and gellation. The composition comprise at least one aqueous dispersion of (1) at least one emulsion copolymer polymerized from (a) at least one ethylenically unsaturated anionic monomer and (b) at least one other olefinically unsaturated monomer, said copolymer being made using at least one phosphate surfactant having at least one phosphorus acid group or salt thereof, said copolymer being crosslinked, and (2) at least one non-water soluble metal pigment. The compositions are useful in paints and other coatings.