Abstract: A circuit and a method for optimizing data frequency and power consumption has a circuit comprising a flip flop which comprises a plurality of latches interconnected. Each latch of the plurality of latches comprises a plurality of pairs of transistors comprising a first plurality of transistors. The at least one transistor of the first plurality of transistors is connected to ground and at least another transistor of the first plurality of transistors is connected to power supply. Further, each latch of the plurality of latches comprises a second plurality of transistors and a third plurality of transistors. The third plurality of transistors is configured between the first plurality of transistors and the second plurality of transistors. Further, each transistor of the third plurality of transistors is connected to at least one of a transistor of the first plurality of transistors or a transistor of the second plurality of transistors.

Abstract: In some implementations, a system may obtain a specification associated with an application programming interface (API). The system may generate a test object based on the specification associated with the API. The test object may include information associated with a set of test cases for the API. The system may identify a framework associated with a test suite to be generated for the API. The system may generate the test suite for the API based on the test object and the identified framework. The system may provide information associated with the test suite for the API.

Abstract: The present disclosure provides for compounds of the general Formula (I) wherein R1a, R1b, R2, R3, R4, R5, R6, R7, R8, and Ring A have any of the values defined in the specification, and pharmaceutically acceptable salts thereof.

Abstract: Various embodiments for authenticating a product associated with a batch production are disclosed. Embodiments disclosed involve scanning a tag affixed on the product and operating a processor to retrieve product identification information which includes an encrypted first chain identifier. The processor then identifies a smart contract for authenticating the product, retrieves from a genesis record stored on the blockchain a batch creation time for the product, and transmits to the smart contract, information to decrypt the smart contract to obtain a second decryption key fragment. The processor then decrypts the first chain identifier using the first decryption key fragment and the second decryption key fragment and determines whether the product is authentic based on a comparison of the batch creation times included in the first chain identifier and the genesis record. Various embodiments for generating tag information for tags affixable to products associated with a batch production are also disclosed.

Abstract: A communication network includes first switches interconnected with second switches. Each first switch includes a first integrated circuit (IC) switch chip, downlink ports, and uplink ports. Each second switch includes ports coupled to at least one uplink port of each of the first switches, and a second IC switch chip in an IC package. To permit each second IC switch chip to forward packets amongst a large number of first switches and to reduce a number of external interconnects of the IC package, each second IC switch chip includes sets of multiplexer/demultiplexer circuitry, each multiplexer/demultiplexer circuitry being coupled between an external interconnect, and a set of multiple internal network interfaces of the second IC switch chip. The multiplexer/demultiplexer circuitry demultiplexes a data stream from the external interconnect to multiple internal network interfaces, and multiplexes multiple data streams from the multiple internal network interfaces to the external interconnect.

Abstract: Systems for packet handling over a network, the systems including a client device configured to communicate over a network, the client device further including a Multi Tenant Module-Client module (MTM-Client module) having processor-readable instructions to direct at least one client device processor to determine whether a packet is a Synchronize packet and, if so, the MTM-Client module opens a pair of streams with consecutive stream IDs to communicate over the network, and the first stream of the pair carries a 5-tuple and metadata for the communication from the client device, and the second stream of the pair carries the TCP packet for the communication from the client device.

Abstract: Systems for packet handling over a network, the systems including a client device configured to communicate over a network, the client device further including a Multi Tenant Module-Client module (MTM-Client module) having processor-readable instructions to direct at least one client device processor to determine whether a packet is a Synchronize packet and, if so, the MTM-Client module opens a pair of streams with consecutive stream IDs to communicate over the network, and the first stream of the pair carries a 5-tuple and metadata for the communication from the client device, and the second stream of the pair carries the TCP packet for the communication from the client device.

Abstract: Performance of a substitute upstream processing component is tested, in order to determine whether that performance is sufficient to support a downstream processing component, within an autonomous driving system, in place of an existing upstream processing component. The existing upstream processing component and the substitute upstream processing component are mutually interchangeable in so far as they provide the same form of outputs interpretable by the downstream processing component, such that either upstream processing component may be used without modification to the downstream processing component. A direct or indirect metric-based comparison is formulated in terms of the resulting performance of the downstream processing component.

Abstract: The present disclosure provides macrocyclic compounds inspired by the immunophilin ligand family of natural products FK506 and rapamycin. The generation of a Rapafucin library of macrocycles that contain FK506 and rapamycin binding domains should have great potential as new leads for developing drugs to be used for treating diseases.

Abstract: The present disclosure provides for compounds of the general Formula (I) wherein R1a, R1b, R2, R3, R4, R5, R6, R7, R8, and Ring A have any of the values defined in the specification, and pharmaceutically acceptable salts thereof.

Abstract: The present disclosure provides macrocyclic compounds inspired by the immunophilin ligand family of natural products FK506 and rapamycin. The generation of a Rapafucin library of macrocyles that contain FK506 and rapamycin binding domains should have great potential as new leads for developing drugs to be used for treating diseases.

Abstract: A system and method for automatic optimization of user engagement on a digital platform is provided. The method comprises generating, a set of tokens for a gamified challenge on the digital platform. The method thereafter leads to associating token(s) from the set of tokens with a set of levels of the gamified challenge. Further the method encompasses providing to user(s) via the digital platform, action item(s) at least to enable the user(s) to retrieve token(s) from the set of tokens and to permit the user(s) to transition to a next level from a current level. Further the method comprises determining for each level, a probability of retrieving the token(s) by the user(s). The method thereafter encompasses automatically controlling, a number of users permitted to transition to the next level from the current level based on the determined probability, to automatically optimize the user engagement on the digital platform.

Abstract: Systems and methods for providing alternate deal structures are disclosed. A method may include: receiving an application for a loan having a loan structure comprising loan parameters from a dealer or an individual; retrieving data for the individual from a third party data source; decisioning the initial loan structure using the parameters and the cached data; returning an approval for the initial loan structure and an interest rate for the initial loan structure to the dealer or the individual; generating additional loan structures, each having a plurality of different parameters; decisioning the additional loan structures using the different parameters and the cached data; ranking the additional loan structures with the interest rate for each additional loan structure; returning approval and the interest rate for the ranked loan structures to the dealer or the individual; and receiving acceptance of the initial loan structure or one of the additional loan structures.

Abstract: The present disclosure provides for compounds of the general Formula (I) wherein R1a, R1b, R2, R3, R4, R5, R6, R7, R8, and Ring A have any of the values defined in the specification, and pharmaceutically acceptable salts thereof.

Abstract: Systems for packet handling over a network, the systems including a client device configured to communicate over a network, the client device further including a Multi Tenant Module—Client module (MTM-Client module) having processor-readable instructions to direct at least one client device processor to determine whether a packet is a Synchronize packet and, if so, the MTM-Client module opens a pair of streams with consecutive stream IDs to communicate over the network, and the first stream of the pair carries a 5-tuple and metadata for the communication from the client device, and the second stream of the pair carries the TCP packet for the communication from the client device.

Abstract: The present disclosure relates to a method for deploying an intelligent edge cluster model includes checking an application requirement and a key performance indicator at a first edge node, dynamically assigning a first resource from the resources in the virtual resource pool of the intelligent edge cluster model to the first edge node, instructing a command to another edge node to assign one or more resources to the first edge node. In particular, the intelligent edge cluster model includes edge nodes and master controller having corresponding one or more resources combined to form the virtual resource pool.

Abstract: The present disclosure provides macrocyclic compounds inspired by the immunophilin ligand family of natural products FK506 and rapamycin. The generation of a Rapafucin library of macrocyles that contain FK506 and rapamycin binding domains should have great potential as new leads for developing drugs to be used for treating diseases.

Abstract: The present disclosure provides neuroprotective compounds along with their use in treating disease such as Parkinson's disease (PD). The compounds can be used as inhibitors for Parthanatos Associated AIF (apoptosis-inducing factor) Nuclease (PAAN), also known as macrophage migration inhibitor factor (MIF).

Abstract: The present disclosure provides macrocyclic compounds inspired by the immunophilin ligand family of natural products FK506 and rapamycin. The generation of a Rapafucin library of macrocyles that contain FK506 and rapamycin binding domains should have great potential as new leads for developing drugs to be used for treating diseases.

Abstract: The present invention generally relates to a self-charging system for electric vehicles comprises at least one gearbox comprises an input end and an output end mechanically coupled to one of the wheels of a vehicle to the input end to generate a rotational energy with an increased output of one of the torque or speed (RPM) to the output end; an auxiliary generator connected to the output end of the at least one gearbox to convert the rotational energy into electrical energy; a controller equipped with a maximum power point tracker to produce maximum power output; and a charger controller coupled to the maximum power point tracker to charge a batter of the vehicle upon limiting electric current rate of the power output to protect against electrical overload, overcharging, and overvoltage.