Abstract: The invention relates to the field of biomedicine. Specifically, the invention relates to a specific PD-L1 binding polypeptide and uses thereof in particular, uses m detecting and/or diagnosing PD-L1 related diseases such as cancers.

Abstract: A method for processing an account in a blockchain is provided. A freezing instruction with respect to a target account is received by a computer device. A freezing lock is generated by the computer device based on the received freezing instruction, the freezing lock including a freezing lock public key. A first freezing request is generated by the computer device based on the freezing instruction and the freezing lock public key. The first freezing request is transmitted by the computer device to a device in the blockchain. The first freezing request is a request based on which the target account is frozen by using the freezing lock and resource transfer of the target account is denied.

Abstract: The present disclosure relates to a celastrol or a pharmaceutically acceptable salt thereof, and a use thereof in the manufacture of a medicament for preventing and/or treating a cholestatic liver disease or a liver fibrosis.

Abstract: The present disclosure provides, among other things, methods and devices for single cells/particle selection and isolation from a sample in a light-curable biomatrix gel. The individual cells or particles are observed by microscopy and manipulated and isolated by accurately controlling the light transmission from a liquid crystal display (LCD) oriented under the sample to provide a detailed image of the sample. In some embodiments, selected cells or particles are then immobilized by curing the biomatrix gel with blue/violet light transmitted from a LED pixel array. In other embodiments, the selected cells or particles of interest are allowed to remain mobile. In either embodiment, the individual cells or particles of interest are segregated from and isolated from the remainder of the sample.

Abstract: Aspects of the disclosure provide methods and apparatuses for storing data. In some examples, an information processing apparatus that includes processing circuitry is provided. The processing circuitry is configured to receive data and determine a target blockchain based on an attribute associated with the data and blockchain correspondence information. The blockchain correspondence information indicates attributes associated with a plurality of blockchains. Further, the processing circuitry is configured to store a first block that is generated based on the received data in the target blockchain.

Abstract: In implementations of the subject matter described herein, a new approach for transferring content between applications is proposed. Generally speaking, in operation, a user can select an area on a user interface in order to cover content that the user wants to transfer. In response, the type of the content in the selected area will be identified. One or more options are then provided on the user interface based on the identified type, and each option may link to one or more applications. Upon a user's selection of an option, an application associated with the selected option is launched to process the content. In this way, the content can be effectively and efficiently processed across different applications, which will significantly improve the processing efficiency and user experience.

Abstract: Aspects of the disclosure provide methods and apparatuses for storing service data. In some examples, an apparatus for storing service data includes processing circuitry. The processing circuitry receives service data of a user and determines, in a plurality of blockchains, a target blockchain according to a user attribute of the user. Based on the service data and an eigenvalue of a block header of a first block in the target blockchain, the processing circuitry generates a second block in the target blockchain. The first block is a previous block of the second block. The second block is used for recording the service data.

Abstract: An electronic bill management method performed in an electronic bill management system is provided. A bill issuance request of a first user including original bill information is received. A first bill account corresponding to the first user is generated based on the original bill information, and account information of the first bill account is stored to an account table in the electronic bill management system. A second block is generated based on the bill issuance request, the first bill account, and a block header eigenvalue of a first block in a block chain in the electronic bill management system. The first block is a previous block of the second block in the block chain, and a bill issuance event of the first user is recorded based on the second block. An issuance success message is transmitted to the first user, the issuance success message including the first bill account.

Abstract: The present disclosure provides a chassis comprising a frame, two hanging units symmetrically provided at both sides of the frame, and a front guiding wheel and a rear universal wheel provided below the frame, wherein each of the hanging units comprises a mounting rack fixedly connected to the frame, a hanging rack slidably connected to the mounting rack, and a driving wheel rotatably connected to the hanging rack, and the front guiding wheel is provided with a first driving motor, and the driving wheel of each hanging unit is driven by a second driving motor, and wherein a closed loop speed control system is formed between the first driving motor and both second driving motors, such that a rotational angle of the front guiding wheel is adjustable via the first driving motor when revolving speeds of both second driving motors are changed.

Abstract: A composition comprising catalase, a preparation method and a use thereof, and a method for killing tumor cells are provided. The composition comprises a radionuclide labeled to a biomacromolecule, a soluble alginate and catalase. The composition can be injected into the tumor through an interventional treatment. A gel is formed when an alginate ion in the composition enters the tumor and encounters a calcium ion, such that the radionuclide and the catalase are uniformly confined in the tumor. The composition comprising catalase utilizes catalase to decompose dissolved oxygen generated from hydrogen peroxide in the tumor to advance the hypoxic state of the tumor cells, and the tumor cells are killed with radiation after the hypoxic state thereof has been advanced, and thus the invention has good prospects for applications in cancer therapy.

Abstract: The present application provides a resource transfer method based on near field communication. The method includes: acquiring a user identifier of a current login user in a first resource management client by a resource transfer terminal of a target merchant in response to triggering of the first resource management client, and outputting target merchant authentication information; in response to determining that the resource transfer terminal has enabled a fixed quantity resource transfer mode, generating a resource transfer order according to a preset quantity of resources transferred by a single order; and adding a user signature and a merchant signature to the resource transfer order, and then accepting the resource transfer order with the signatures.

Abstract: A method for processing account information in a block chain is provided. A computer device receives identity information and a transfer request, the transfer request requesting to transfer a resource in an account to a target account, the target account being generated by a certificate center. The computer device obtains owner information of the account from the certificate center according to the transfer request. The computer device compares the identity information and the owner information. The computer device transmits an authentication request to the block chain in response to determining that the identity information and the owner information are consistent, the authentication request requesting the block chain to transfer the resource in the account to the target account.

Abstract: A resource transfer terminal comprises a housing and a near field communication module supported by the housing. The near field communication module is configured to be operable in a passive mode, and sense a resource transfer signal transmitted by a user device, and operates in response to the resource transfer signal. The near field communication module is provided with a resource transfer key and/or a verification key.

Abstract: This application discloses a node device operation method, a work status switching apparatus, a node device, and a medium, and relates to the field of network technologies. The method includes: receiving voting requests of a plurality of node devices, a quantity of the plurality of node devices being greater than half a quantity of node devices in a system; obtaining cycle length information and latest log indexes from the voting requests of the plurality of node devices if a current node device operates in a leader state; and switching a current work status from the leader state to a follower state or a candidate state if all the cycle length information in the voting requests of the plurality of node devices is greater than cycle length information of the current node device and all the latest log indexes in the voting requests of the plurality of node devices are not less than a latest log index of the current node device.

Abstract: This application relates to a shared data recovery method performed at a first node of a data sharing system. The first node obtains a first eigenvalue of a first node after receiving a recovery request carrying a first block height; broadcasts the first eigenvalue to at least one second node and recovery indication information to the at least one second node. After determining, based on the first eigenvalue and a plurality of second eigenvalues, that data in shared data stored by all nodes of the data sharing system is consistent, the first node recovers data within a range of the first block height in the shared data after receiving a preset quantity of a plurality of pieces of recovery indication information, thereby ensuring consistency and security of data included in a block, and reducing pressure on a node of the data sharing system to store the shared data.

Abstract: A method for processing account information in a block chain is provided. A computer device receives identity information and a transfer request, the transfer request requesting to transfer a resource in an account to a target account, the target account being generated by a certificate center. The computer device obtains owner information of the account from the certificate center according to the transfer request. The computer device compares the identity information and the owner information. The computer device transmits an authentication request to the block chain in response to determining that the identity information and the owner information are consistent, the authentication request requesting the block chain to transfer the resource in the account to the target account.

Abstract: The present disclosure provides computing systems and methods directed to active learning and may provide advantages or improvements to active learning applications for skewed data sets. A challenge in training and developing high-quality models for many supervised learning scenarios is obtaining labeled training examples. This disclosure provides systems and methods for active learning on a training dataset that includes both labeled and unlabeled datapoints. In particular, the systems and methods described herein can select (e.g., at each of a number of iterations) a number of the unlabeled datapoints for which labels should be obtained to gain additional labeled datapoints on which to train a machine-learned model (e.g., machine-learned classifier model). Generally, the disclosure provides cost-effective methods and systems for selecting data to improve machine-learned models in applications such as the identification of content items in text, images, and/or audio.

Abstract: The present disclosure provides, among other things, methods for generating antibodies against a target protein. In some embodiments, a library is provided comprising a plurality of tether antibodies comprising an antigen binding region and a ligand that binds to a target protein. In some embodiments, a library is provided comprising a plurality of candidate antibodies for binding to a target protein.

Abstract: A finger of a robotic hand includes a phalanx portion including at least two phalanxes rotatably coupled to each other, a driving device including a rotating member, a connection assembly including a housing defining a sliding groove that includes a first end and a second end defining a through hole that is in communication with the sliding groove, a cap connected to the housing at the first end, a sliding rod comprising a base slidably received in the sliding groove and a rod protruding from the base, and an elastic member received in the sliding groove and having opposite ends that respectively abut against the base and an inner surface of the second end, and a rope including two opposite ends respectively connected to the cap and one of the at least two phalanxes.

Abstract: A finger of a robotic hand includes a phalanx portion including at least two phalanxes rotatably coupled to each other, a driving device including a rotating member, a connection assembly including a housing defining a sliding groove that includes a first end and a second end defining a through hole that is in communication with the sliding groove, a cap connected to the housing at the first end, a sliding rod comprising a base slidably received in the sliding groove and a rod protruding from the base, and an elastic member received in the sliding groove and having opposite ends that respectively abut against the base and an inner surface of the second end, and a rope including two opposite ends respectively connected to the cap and one of the at least two phalanxes.