Patents by Inventor Qian Liu

Qian Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200261588
    Abstract: Disclosed are an intermediate drug having synergistic anticancer activity and a polyethylene glycol-coupled synergistic anticancer drug, and a method preparing therefor and use thereof. The intermediate drug has the general structural formula of (I), and the polyethylene glycol-coupled synergistic anticancer drug has the general structural formula of (II). The drugs achieve the combined medication of various anticancer drugs and avoid the toxic reaction caused by the interaction among the drugs or by the pharmacokinetics of the drugs when taking various anticancer drugs, facilitate overcoming the multidrug resistance of cancers, have a synergistic effect, and can be used for preparing anticancer medicaments and for treating cancers.
    Type: Application
    Filed: January 22, 2018
    Publication date: August 20, 2020
    Applicant: Chongqing Upgra Biological Sci. & Tech., Ltd.
    Inventors: Gaoquan LI, Bin WANG, Dajun LI, Qian ZHANG, Lei HUANG, Maofen CHEN, Xiaodan WU, Liangyan PENG, Tingting HE, Yanyan ZHANG, Yun TANG, Huan LIU, Jvyuan SHUI, Cuifang ZHANG, Jianhuan LI
  • Patent number: 10747598
    Abstract: In various example embodiments, a system and method for synchronization of messages based on queues are presented. One or more electronic messages are received according a message order. A message queue that corresponds to the first user is generated. The one or more messages in the message queue are stored based on the received message order. A position of a next message in the generated message queue to be transmitted is determined. The message from the determined position in the message queue is transmitted to the client device operated by the first user.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: August 18, 2020
    Assignee: Beijing Yi Zhang Yun Feng Technology Co., Ltd.
    Inventors: Junyan Liu, Xiaoyu Ma, Yupeng Liang, Chunye Wang, Qian Huang
  • Patent number: 10741567
    Abstract: A memory cell includes a select device and a capacitor electrically coupled in series with the select device. The capacitor includes two conductive capacitor electrodes having ferroelectric material there-between. The capacitor has an intrinsic current leakage path from one of the capacitor electrodes to the other through the ferroelectric material. There is a parallel current leakage path from the one capacitor electrode to the other. The parallel current leakage path is circuit-parallel the intrinsic path and of lower total resistance than the intrinsic path. Other aspects are disclosed.
    Type: Grant
    Filed: February 25, 2019
    Date of Patent: August 11, 2020
    Assignee: Micron Technology, Inc.
    Inventors: Kamal M. Karda, Qian Tao, Durai Vishak Nirmal Ramaswamy, Haitao Liu, Kirk D. Prall, Ashonita Chavan
  • Patent number: 10739646
    Abstract: A reflective semiconductor device includes integrated circuitry disposed in a semiconductor layer. A first plurality of mirrors is formed in a mirror layer over the semiconductor layer, and each of the first plurality of mirrors is spaced apart from one another by at least a uniform width. A thin dielectric film layer covers sidewalls of the first plurality of mirrors and the semiconductor layer in the regions between the spaced apart first plurality of mirrors. A second plurality of mirrors are formed in the mirror layer between the thin dielectric film layer covered sidewalls of the first plurality of mirrors and over the thin dielectric film layer covering the semiconductor layer. Each one of the first and second plurality of mirrors has the uniform width, and is coupled to the integrated circuitry disposed in the semiconductor layer.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: August 11, 2020
    Assignee: OmniVision Technologies, Inc.
    Inventors: Ming Zhang, Yin Qian, Libo Weng, Dyson H. Tai, Chia-Ying Liu, Chia-Jung Liu
  • Publication number: 20200252111
    Abstract: A method for operating a communication device includes receiving a first transmission including a first signal on one or more resources associated with signal reception, deriving a receive filter in accordance with the received first transmission, deriving a transmit filter in accordance with the receive filter, precoding a second signal with the transmit filter, thereby producing a second transmission, and transmitting the second transmission.
    Type: Application
    Filed: April 24, 2020
    Publication date: August 6, 2020
    Inventors: Diana Maamari, Jialing Liu, Qian Cheng, Weimin Xiao, Hao Zhou, Anthony C.K. Soong
  • Publication number: 20200252117
    Abstract: Various methods and systems are provided to provide for Channel State Information (CSI) feedback of hybrid beamforming. In a first example embodiment, a method for signaling a beamforming reference signal (BFRS) is provided. A resource block is created for the BFRS, the resource block containing a plurality of resource elements, each resource element defined by a time-frequency resource within one subcarrier and one multiplexing symbol. A total number of analog transmit beams for the BFRS is then determined, along with grouping information for the analog transmit beams for the BFRS. Then, the resource block, the total number of analog beams, and the grouping information are transmitted from a first network controller to a user equipment (UE). Then the BFRS is transmitted from the first network controller to the UE.
    Type: Application
    Filed: February 4, 2020
    Publication date: August 6, 2020
    Applicant: Futurewei Technologies, Inc.
    Inventors: Qian Cheng, Weimin Xiao, Jialing Liu
  • Patent number: 10732070
    Abstract: A load-sensitive multi-path valve testing device includes the first, second, and third pressure sensors connected to the T, P, and LS ports of the load-sensitive multi-path valve; an oil outlet of an electronically controlled variable displacement pump connected to the P port of the load-sensitive multi-path valve via an oil supply pipeline; a first proportional relief valve and a first flow sensor connected on the oil supply pipeline; control oil ports of each commutation linkage respectively connected to a control oil source by two proportional pressure reducing valves; two working oil ports of each commutation linkage respectively connected to an oil tank by two proportional relief valves; flow sensors and pressure sensors arranged on two working oil ports of each commutation linkage. A testing method includes: using the device for pressure loss tests, micro-motion characteristic tests and flow saturation resistant characteristic tests.
    Type: Grant
    Filed: June 17, 2018
    Date of Patent: August 4, 2020
    Assignee: Xuzhou University of Technology
    Inventors: Lei Zhang, Chuanhui Huang, Yan Dong, Qian Wang, Lei Liu
  • Patent number: 10729337
    Abstract: The present application relates to systems and methods for non-invasively determining at least one of left ventricular end diastolic pressure (LVEDP) or pulmonary capillary wedge pressure (PCWP) in a subject's heart, comprising: receiving, by a computer, a plurality of signals from a plurality of non-invasive sensors that measure a plurality of physiological effects that are correlated with functioning of said subject's heart, said plurality of physiological effects including at least one signal correlated with left ventricular blood pressure and at least one signal correlated with timing of heartbeat cycles of said subject's heart; training a machine learning model on said computer using said plurality of signals for periods of time in which said plurality of signals were being generated during a heart failure event of said subject's heart; determining said LVEDP or PCWP using said machine learning model at a time subsequent to said training and subsequent to said heart failure event.
    Type: Grant
    Filed: May 5, 2016
    Date of Patent: August 4, 2020
    Assignees: The Johns Hopkins University, Boston Scientific Scimed Inc.
    Inventors: Qian Liu, Nichaluk Leartprapun, Jackline Wanjala, Soumyadipta Acharya, Andrew Bicek, Viachaslau Barodka, Umang Anand, Majd Alghatrif, David Kass, B. Westbrook Bernier, Chao-Wei Hwang, Peter Johnston, Trent Langston
  • Patent number: 10734415
    Abstract: Display panel and display device are provided. The display panel includes a display region; a non-display region; and a notch. Data lines are disposed in the display region. An edge of the display panel recesses toward the display region to form the notch. The display region includes a first display region and second display regions. The notch and the first display regions are disposed between two second display regions in the first direction and are adjacent in the second direction. The data lines include first data lines in each of the second display regions separated by the notch. Connection lines are disposed surrounding the at least one notch, and each connection line connects two of the first data lines in a same column and on two sides of the notch At least a portion of the connection lines includes first segments disposed in the first display region.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: August 4, 2020
    Assignee: SHANGHAI TIANMA AM-OLED CO., LTD.
    Inventors: Xinzhao Liu, Kaihong Huang, Min Chen, Lin Cheng, Zhuan Gao, Ciyi Gu, Jing Lv, Haoshen Wang, Qingxia Wang, Xiaoyu Wang, Zi Xu, Jiayao Yang, Qian Zhang, Peng Zhang
  • Publication number: 20200239470
    Abstract: The present invention discloses a substituted pyridine compound represented by formula I, and a pharmaceutically acceptable salt, stereoisomer and tautomer thereof. The compounds of the present invention are useful in the treatment of cancers.
    Type: Application
    Filed: April 15, 2020
    Publication date: July 30, 2020
    Inventors: Guangxin XIA, Qian WANG, Chen SHI, Xiong ZHAI, Hui GE, Xuemei LIAO, Yu MAO, Zhixiong XIANG, Yanan HAN, Guoyong HUO, Yanjun LIU
  • Publication number: 20200239510
    Abstract: Provided are crystalline forms of a compound having an inhibitory effect on sodium-dependent glucose cotransporter SGLT2. The invention also provides pharmaceutical compositions, methods of preparing the crystalline compound, and methods of using the crystalline compound, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT or SGLT2 inhibition.
    Type: Application
    Filed: November 25, 2019
    Publication date: July 30, 2020
    Inventors: Mengzhuang CAI, Qian LIU, Ge XU, Binhua LV, Brian SEED, Jacques ROBERGE
  • Publication number: 20200243562
    Abstract: Display panel and display device are provided. The display panel includes a display region; a non-display region; and a notch. Data lines are disposed in the display region. An edge of the display panel recesses toward the display region to form the notch. The display region includes a first display region and second display regions. The notch and the first display regions are disposed between two second display regions in the first direction and are adjacent in the second direction. The data lines include first data lines in each of the second display regions separated by the notch. Connection lines are disposed surrounding the at least one notch, and each connection line connects two of the first data lines in a same column and on two sides of the notch. At least a portion of the connection lines includes first segments disposed in the first display region.
    Type: Application
    Filed: April 25, 2019
    Publication date: July 30, 2020
    Inventors: Xinzhao LIU, Kaihong HUANG, Min CHEN, Lin CHENG, Zhuan GAO, Ciyi GU, Jing LV, Haoshen WANG, Qingxia WANG, Xiaoyu WANG, Zi XU, Jiayao YANG, Qian ZHANG, Peng ZHANG
  • Patent number: 10722489
    Abstract: This application discloses a D-3-phosphoglycerate dehydrogenase allosteric inhibitor and the use thereof. In one class is the benzoyl hydrazine compound for the allosteric site MDL-1 of the enzyme, and the other class is the furan compound for the allosteric site MDL-2 of the enzyme. In vitro enzymatic activity tests, cell viability tests and mouse xenograft model experiments confirm that the two classes of allosteric inhibitors can specifically inhibit the activity of D-3-phosphoglycerate dehydrogenase and delay the growth of cancer cells by reducing the overexpression of the enzyme in cancer cells. Same are used alone or in combination, or in combination with other anti-cancer drugs and can treat, prevent, or inhibit tumor diseases, including breast cancer, colon cancer, melanoma and non-small cell lung cancer.
    Type: Grant
    Filed: May 7, 2019
    Date of Patent: July 28, 2020
    Assignee: Peking University
    Inventors: Luhua Lai, Ying Liu, Qian Wang, Pei Liu
  • Publication number: 20200236636
    Abstract: The present disclosure discloses a method of synchronized signal block measurement, a user equipment and a network device. The method includes: receiving auxiliary measurement information, which is transmitted by a network device and is used to assist the UE to perform synchronized signal block measurement; and, determining repetitive synchronized signal blocks according to the auxiliary measurement information. The auxiliary measurement information is used to indicate transmission configuration information of synchronized signal blocks.
    Type: Application
    Filed: August 31, 2018
    Publication date: July 23, 2020
    Applicant: VIVO MOBILE COMMUNICATION CO., LTD.
    Inventors: Siqi LIU, Yu DING, Zichao JI, Xueming PAN, Qian ZHENG
  • Publication number: 20200223970
    Abstract: A preparation method of comb structure temperature/pH-responsive polycarboxylic acid adopts acrylic ester, temperature/pH-responsive monomer and other raw materials to obtain polycarboxylic acid via acrylate monomer self-polymerization, grafting with temperature/pH-responsive monomers and hydrolyzation. In other words, acrylate is used as the reaction monomer to polymerize polyacrylate with controllable molecular weight under the action of initiator and chain transfer agent, then the graft copolymers are copolymerized with temperature/pH-responsive monomers to obtain graft copolymers with acrylate polymers main chain and temperature/pH-responsive polymer side chains. Finally, the graft copolymer is hydrolyzed to obtain the comb structure temperature/pH-responsive polycarboxylic acid with polyacrylic acid main chain and temperature/pH-responsive monomer side chain.
    Type: Application
    Filed: September 13, 2019
    Publication date: July 16, 2020
    Inventors: XIAO LIU, QIAN XU, ZIMING WANG, GUANGHONG LAI, JIANAN GUAN, SHANSHAN QIAN, XIABING BAI
  • Patent number: 10710875
    Abstract: In described examples, a device mounted on a substrate includes an encapsulant. In at least one example, an encapsulant barrier is deposited along a scribe line, along which the substrate is singulatable. To encapsulate one or more terminals of the substrate, an encapsulant is deposited between the encapsulant barrier and an edge of the device parallel to the encapsulant barrier.
    Type: Grant
    Filed: November 13, 2017
    Date of Patent: July 14, 2020
    Assignee: TEXAS INSTRUMENTS INCORPORATED
    Inventors: Jane Qian Liu, Gary Philip Thomson, Richard Allen Richter
  • Patent number: 10702500
    Abstract: One embodiment is a method of treating cancer. The method includes administering a therapeutically effective amount of a compound to a patient.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: July 7, 2020
    Assignee: MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Xiao Jun Yao, Lai Han Elaine Leung, Liang Liu, Qian Qian Wang, Jia Hui Xu, Ying Li
  • Publication number: 20200212250
    Abstract: A method for processing an integrated optical circuit chip includes securing a panel dam around a periphery of an array of integrated optical circuit chips that share a substrate. The method also includes filling an area circumscribed by the panel dam with an insulating polymer to a level below a top surface of the integrated optical circuit chips. The method further includes singulating a given integrated optical circuit chip in the array of integrated optical circuit chips.
    Type: Application
    Filed: December 27, 2018
    Publication date: July 2, 2020
    Inventors: JANE QIAN LIU, GARY PHILIP THOMSON
  • Publication number: 20200211811
    Abstract: A multi-beam inspection apparatus including an improved source conversion unit is disclosed. The improved source conversion unit may comprise a micro-structure deflector array including a plurality of multipole structures. The micro-deflector deflector array may comprise a first multipole structure having a first radial shift from a central axis of the array and a second multipole structure having a second radial shift from the central axis of the array. The first radial shift is larger than the second radial shift, and the first multipole structure comprises a greater number of pole electrodes than the second multipole structure to reduce deflection aberrations when the plurality of multipole structures deflects a plurality of charged particle beams.
    Type: Application
    Filed: December 27, 2019
    Publication date: July 2, 2020
    Inventors: Weiming REN, Qian ZHANG, Xuerang HU, Xuedong LIU
  • Publication number: 20200212125
    Abstract: A display substrate and a display device. The display substrate includes a first sub-pixel, a second sub-pixel, and a first spacer. A line connecting the center of the first sub-pixel and the center of the second sub-pixel is a center line; the center line is not perpendicular to a first direction; the first direction is at least one of the row direction or the column direction. The first spacer is disposed between the first sub-pixel and the second sub-pixel, and the extension direction of first spacer between the first sub-pixel and the second sub-pixel is not perpendicular to the first direction.
    Type: Application
    Filed: December 28, 2018
    Publication date: July 2, 2020
    Applicant: BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Libin LIU, Qian YANG, Hongli WANG, Lujiang HUANGFU