Patents by Inventor Qian Shi

Qian Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250042867
    Abstract: The present invention relates to a process for producing succinic anhydride by maleic anhydride hydrogenation, comprising (1) feeding a maleic anhydride solution and a hydrogen raw material respectively to a first-stage hydrogenation reactor from an upper liquid-phase feed port and a top gas-phase feed port of the first-stage hydrogenation reactor for a first-stage hydrogenation reaction to obtain a first-stage hydrogenation product; (2) feeding the first-stage hydrogenation product to a second-stage hydrogenation reactor for a second-stage hydrogenation reaction to obtain a second-stage hydrogenation product, optionally, before entering the second-stage hydrogenation reactor, subjecting the first-stage hydrogenation product to a first-stage gas-liquid separation to obtain a first-stage gas phase and a first-stage liquid phase, and then feeding the first-stage gas phase and the first-stage liquid phase respectively from a top gas-phase feed port and an upper liquid-phase feed port of the second-stage hydrogen
    Type: Application
    Filed: October 21, 2022
    Publication date: February 6, 2025
    Inventors: Changjiang WU, Guoqing WANG, Dongfeng LI, Liang GUO, Lijun ZHANG, Yan LI, Hui PENG, Shujuan LUO, Jun TIAN, Huimin SHI, Yuehui ZHU, Dongshun ZHANG, Jieming YE, Chunfang LI, Shuliang LU, Yang XU, Qian SHI
  • Publication number: 20240144119
    Abstract: Provided is a process including: determining, based on a machine learning model, a measure of outcome success for a set of job requisitions, the machine learning model trained to determine measures of outcome success for job requisitions based on a set of job requisition training data, and the set of job requisition training data comprising: a set of historical job requisitions; and job outcomes for the set of historical job requisitions; ranking, based on the measure of outcome success, the set of job requisitions to generate a ranked set of job requisitions; and providing, to a job candidate, one or more job requisitions of the ranked set of job requisitions for selection of a job requisition for application by the job candidate.
    Type: Application
    Filed: October 28, 2022
    Publication date: May 2, 2024
    Inventors: Liming Zhao, Alexander G. Nazem, Travis Sanders, Julia Karpf, Qian Shi, Lucas Calero Forero
  • Publication number: 20240109246
    Abstract: In one example in accordance with the present disclosure, an additive manufacturing system is described. The additive manufacturing system includes a build material deposition device to form a plastically deformable three-dimensional (3D) object by depositing layers of a thermoplastic build material to form a body of the plastically deformable 3D object. The additive manufacturing system also includes a heat channel forming device to form heat channels within the plastically deformable 3D object which heat channels, responsive to an applied stimulus, are to soften adjacent regions of the body. The additive manufacturing system also includes a fusing system to selectively harden layers of thermoplastic build material to form the plastically deformable 3D object.
    Type: Application
    Filed: February 19, 2021
    Publication date: April 4, 2024
    Inventors: Juha SONG, Kiesar Sideeq BHAT, Qian SHI, Muhammad Aidil BIN JUHARI, Aravind Kumar JAYASANKAR, Rui Yuan HAN, Rafael BALLAGAS, Michael John REGAN
  • Patent number: 11932734
    Abstract: Various methods of reshaping and recycling thermoset polymers and composites containing thermoset polymers are provided. The methods involve the bond exchange reaction of exchangeable covalent bonds in the polymer matrix with a suitable small molecule solvent in the presence of a catalyst. In some aspects, the methods are applied to a carbon fiber reinforced polymer or a thermoset polymer where the thermoset polymer matrix includes a plurality of ester bonds. Using a small molecule alcohol, the methods provide for recycling one or both of the carbon fiber and the polymer, for welding two surfaces, or for repairing a damaged surface in the materials.
    Type: Grant
    Filed: August 12, 2022
    Date of Patent: March 19, 2024
    Assignee: Georgia Tech Research Corporation
    Inventors: Hang Qi, Kai Yu, Qian Shi, Xiao Kuang
  • Publication number: 20220389185
    Abstract: Various methods of reshaping and recycling thermoset polymers and composites containing thermoset polymers are provided. The methods involve the bond exchange reaction of exchangeable covalent bonds in the polymer matrix with a suitable small molecule solvent in the presence of a catalyst. In some aspects, the methods are applied to a carbon fiber reinforced polymer or a thermoset polymer where the thermoset polymer matrix includes a plurality of ester bonds. Using a small molecule alcohol, the methods provide for recycling one or both of the carbon fiber and the polymer, for welding two surfaces, or for repairing a damaged surface in the materials.
    Type: Application
    Filed: August 12, 2022
    Publication date: December 8, 2022
    Inventors: Hang Qi, Kai Yu, Qian Shi, Xiao Kuang
  • Publication number: 20220306713
    Abstract: Provided is a protein comprising an antibody or antigen-binding fragment and an interleukin molecule operably linked to the antibody or antigen-binding fragment. The antibody or antigen-binding fragment specifically binds to an immune checkpoint protein. The interleukin molecule is IL-10.
    Type: Application
    Filed: June 10, 2020
    Publication date: September 29, 2022
    Inventors: Lan YANG, Guoliang YU, Qian SHI, Zhongwei FEI, Biao MA
  • Patent number: 11421095
    Abstract: Various methods of reshaping and recycling thermoset polymers and composites containing thermoset polymers are provided. The methods involve the bond exchange reaction of exchangeable covalent bonds in the polymer matrix with a suitable small molecule solvent in the presence of a catalyst. In some aspects, the methods are applied to a carbon fiber reinforced polymer or a thermoset polymer where the thermoset polymer matrix includes a plurality of ester bonds. Using a small molecule alcohol, the methods provide for recycling one or both of the carbon fiber and the polymer, for welding two surfaces, or for repairing a damaged surface in the materials.
    Type: Grant
    Filed: November 4, 2020
    Date of Patent: August 23, 2022
    Assignee: Georgia Tech Research Corporation
    Inventors: Hang Qi, Kai Yu, Qian Shi, Xiao Kuang
  • Publication number: 20220252603
    Abstract: Provided herein is related generally to the field of molecular biology and growth factor regulation. More specifically, provided herein are methods useful for treating cancer patient using c-Met inhibitor based on the identification of an increased c-Met expression and at least one c-Met gene alteration, e.g. c-Met mutation, c-Met fusion gene and c-Met gene amplification.
    Type: Application
    Filed: June 8, 2020
    Publication date: August 11, 2022
    Inventors: Lan YANG, Qian SHI, Sanjeev REDKAR, Guoliang YU, Fabio Maurizio BENEDETTI, Xiaoling ZHANG, Biao MA
  • Publication number: 20220088016
    Abstract: Provided herein are methods of treating cancer in a patient with a tyrosine kinase inhibitor. The method comprises: a) measuring the expression level of a protein kinase in a sample obtained from the patient; b) comparing the expression level of the protein kinase to a corresponding reference expression level; c) determining a likelihood of the patient being responsive to the tyrosine kinase inhibitor; and d) treating the patient whose expression level of the protein kinase indicates that the patient will be responsive with the tyrosine kinase inhibitor.
    Type: Application
    Filed: January 2, 2020
    Publication date: March 24, 2022
    Inventors: Lan YANG, Qian SHI, Guoliang YU
  • Publication number: 20210087353
    Abstract: Various methods of reshaping and recycling thermoset polymers and composites containing thermoset polymers are provided. The methods involve the bond exchange reaction of exchangeable covalent bonds in the polymer matrix with a suitable small molecule solvent in the presence of a catalyst. In some aspects, the methods are applied to a carbon fiber reinforced polymer or a thermoset polymer where the thermoset polymer matrix includes a plurality of ester bonds. Using a small molecule alcohol, the methods provide for recycling one or both of the carbon fiber and the polymer, for welding two surfaces, or for repairing a damaged surface in the materials.
    Type: Application
    Filed: November 4, 2020
    Publication date: March 25, 2021
    Inventors: Hang Qi, Kai Yu, Qian Shi, Xiao Kuang
  • Patent number: 10829612
    Abstract: Various methods of reshaping and recycling thermoset polymers and composites containing thermoset polymers are provided. The methods involve the bond exchange reaction of exchangeable covalent bonds in the polymer matrix with a suitable small molecule solvent in the presence of a catalyst. In some aspects, the methods are applied to a carbon fiber reinforced polymer or a thermoset polymer where the thermoset polymer matrix includes a plurality of ester bonds. Using a small molecule alcohol, the methods provide for recycling one or both of the carbon fiber and the polymer, for welding two surfaces, or for repairing a damaged surface in the materials.
    Type: Grant
    Filed: July 3, 2017
    Date of Patent: November 10, 2020
    Assignee: Georgia Tech Research Corporation
    Inventors: Hang Qi, Kai Yu, Qian Shi
  • Publication number: 20190322835
    Abstract: Various methods of reshaping and recycling thermoset polymers and composites containing thermoset polymers are provided. The methods involve the bond exchange reaction of exchangeable covalent bonds in the polymer matrix with a suitable small molecule solvent in the presence of a catalyst. In some aspects, the methods are applied to a carbon fiber reinforced polymer or a thermoset polymer where the thermoset polymer matrix includes a plurality of ester bonds. Using a small molecule alcohol, the methods provide for recycling one or both of the carbon fiber and the polymer, for welding two surfaces, or for repairing a damaged surface in the materials.
    Type: Application
    Filed: July 3, 2017
    Publication date: October 24, 2019
    Inventors: Hang Qi, Kai Yu, Qian Shi
  • Patent number: 9816327
    Abstract: An information transmission apparatus for logging while drilling comprises a hollow drilling rod and at least one cable. The drilling rod comprises at least one first drilling rod member and at least one second drilling rod member spliced to each other alternately. The first drilling rod member comprises a through hole, and the second drilling rod member comprises a stepped hole. The cable comprises a fixed end, a connected end, and a folded portion connect the fixed end to the connected end. Each of the cables is fixed in the stepped hole through a fixed end or is connected to a connected end of an adjacent cable. The connected end may be stretched along the stepped hole, and stretched through the through hole to be electrically connected to a logging instrument or a fixed end of the adjacent cable. The apparatus provides protection for a cable through a hollow drilling rod, thereby improving the transmission reliability.
    Type: Grant
    Filed: June 18, 2013
    Date of Patent: November 14, 2017
    Assignees: CHINA NATIONAL PETROLEUM CORPORATION, CNPC DRILLING RESEARCH INSTITUTE, BEIJING PETROLEUM MACHINERY FACTORY
    Inventors: Guanghua Liu, Lianyang Zou, Xinli Liu, Yanfu Huang, Shikai Tao, Wenjing Yang, Guoxing Yan, Hongjiang Shi, Tiejun Li, Chen Wang, Qian Shi, Chengqin Sun, Chunhua Zhang, Zhiyong Zhou, Xingming Pan, Qingkui Wu, Zhangjian Li
  • Patent number: 9743646
    Abstract: The present invention provides an immuno-deficient animal useful as an animal model for a human disease associated with a first mutation of a target gene, wherein the animal comprises (a) a first human xenograft comprising the target gene comprising the first mutation; (b) a second human xenograft comprising the target gene but lacking the first mutation, wherein the first human xenograft and second human xenograft are isogenic. Also provided here are methods of producing the animal model and methods of using such animal model.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: August 29, 2017
    Assignee: CROWN BIOSCIENCE INC. (TAICANG)
    Inventors: Qian Shi, Yanmei Sun
  • Patent number: 9562025
    Abstract: The present invention relates to compounds having at least one (substituted phenyl)-propenal moiety. The compounds are useful in treating a subject suffering from an androgen receptor-associated medical condition, e.g., inflammation, acne, alopecia, hirsutism, wound, Spinal and Bulbar Muscular Atrophy (SBMA, Kennedy's Disease), unwanted immune response, immune disorder, or cancer.
    Type: Grant
    Filed: February 16, 2016
    Date of Patent: February 7, 2017
    Assignee: Allianz Pharmascience Ltd.
    Inventors: Charles Shih, Qian Shi, Hui-Kang Wang
  • Publication number: 20170026908
    Abstract: The present disclosure relates to a system and method of managing the use of power in a computing system including for example a wearable computer such as a smart watch. The computing device may include a policy agent implementing one or more stored power management policies relating to download parameters for photos or other content based in part on remaining battery life in the computing device. The stored policies indicate the size reduction for image or media files to be downloaded to the computing device.
    Type: Application
    Filed: July 21, 2015
    Publication date: January 26, 2017
    Inventors: Qian Shi, Jingping Lin, Weilin Luo, Zhiping Jia
  • Publication number: 20160367513
    Abstract: The present invention includes methods and compositions useful for treating and preventing skin disorders, hair loss and other skin disorders. The compositions include an ARD enhancer in combination with a second compound or composition. In some embodiments the second compound is at least one of a bactericide, an antibiotic, an anti-microbial peptide, Vitamin A, a Vitamin A derivative, a retinoid, an anti-inflammatory compound, and anti-androgen compounds.
    Type: Application
    Filed: August 11, 2016
    Publication date: December 22, 2016
    Applicant: AndroScience Corporation
    Inventors: Charles Shih, Ching-Yuan Su, Hui-Kang Wang, Qian Shi
  • Patent number: 9446127
    Abstract: The present invention includes methods and compositions useful for treating and preventing skin disorders, hair loss and other skin disorders. The compositions include an ARD enhancer in combination with a second compound or composition. In some embodiments the second compound is at least one of a bactericide, an antibiotic, an anti-microbial peptide, Vitamin A, a Vitamin A derivative, a retinoid, an anti-inflammatory compound, and anti-androgen compounds.
    Type: Grant
    Filed: July 31, 2008
    Date of Patent: September 20, 2016
    Assignee: AndroScience Corporation
    Inventors: Charles C. Y. Shih, Ching-Yuan Su, Hui-Kang Wang, Qian Shi
  • Publication number: 20160264539
    Abstract: The present invention relates to compounds having at least one (substituted phenyl)-propenal moiety. The compounds are useful in treating a subject suffering from an androgen receptor-associated medical condition, e.g., inflammation, acne, alopecia, hirsutism, wound, Spinal and Bulbar Muscular Atrophy (SBMA, Kennedy's Disease), unwanted immune response, immune disorder, or cancer.
    Type: Application
    Filed: February 16, 2016
    Publication date: September 15, 2016
    Inventors: Charles Shih, Qian Shi, Hui-Kang Wang
  • Patent number: D877193
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: March 3, 2020
    Assignee: ONE App Limited
    Inventors: Wei Li, Qian Shi, Huang Huang