Patents by Inventor Qian Shi

Qian Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130261121
    Abstract: The present invention includes compounds, pharmaceuticals and cosmetics having at least one (substituted phenyl)-propenal moiety. The compounds and compositions of the present invention are useful in the treatment or prevention of medical conditions including androgen associated conditions, androgen associated inflammation, a wound (the compounds assist with wound healing), acne, rheumatoid arthritis, psoriasis, rosacea, and alopecia; Kennedy's disease (spinal and bulbar muscular atrophy, or SBMA), polyglutamine-mediated motor neuron degeneration; cancers such as prostate cancer, bladder cancer, breast cancer, ovarian cancer, hepatocellular (liver) cancer, and pancreatic cancer; and other medical conditions described herein. Treatment of such medical conditions includes administering to an individual suffering from a medical condition describe herein, a therapeutically effective amount of any of the disclosed compounds, their derivatives, or pharmaceutical compositions thereof.
    Type: Application
    Filed: June 18, 2012
    Publication date: October 3, 2013
    Inventors: Charles C.Y. SHIH, Qian Shi, Hui-Kang Wang, Ching-Yuan Su
  • Patent number: 8318441
    Abstract: The present invention provides methods of detecting cancer using biomarkers.
    Type: Grant
    Filed: April 2, 2010
    Date of Patent: November 27, 2012
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Alexander Miron, James Dirk Iglehart, Lyndsay N. Harris, Xin Lu, Qian Shi
  • Publication number: 20120283220
    Abstract: The present invention provides compounds of Formula (I-IV): compositions containing the same, and methods of use thereof such as for the treatment of cancer.
    Type: Application
    Filed: September 22, 2010
    Publication date: November 8, 2012
    Inventors: Kuo-Hsiung Lee, Xiaoming Yang, Qian Shi, Kenneth F. Bastow, Che-Ming Teng, Tse-Ming Hong, Pan-Chyr Yang, Shuenn-Chen Yang
  • Patent number: 8276587
    Abstract: A hand-held, automated qualitative fit tester (QLFT) for establishing gas mask fit integrity. The automated QLFT may be configured to utilize a pressure source in combination with a cartridge and a nebulizer to generate aerosols having size distributions and concentrations that are substantially the same as OSHA-approved manual units. The QLFT may further include a cartridge that contains the aerosol solution used to test mask integrity. The cartridge may be configured to recapture solution that collects on the interior walls of the nebulizer. The automated QLFT may also be equipped with a microprocessor for executing sequences that are in substantive compliance with 29 CFR 1910.134 and for writing to a data storage device. The automated aspects of the invention can reduce or negate the need for operating personnel to repeatedly and manually actuate a squeeze ball and record results manually, as is required with present OSHA-approved hand-held aerosol generators.
    Type: Grant
    Filed: February 17, 2009
    Date of Patent: October 2, 2012
    Assignee: TSI, Incorporated
    Inventors: Hai Zhang, Will Zanto, Qian Shi, Greg Olson, Phillip Poeschl, Vincent Majkowski, Stuart J. Olstad
  • Publication number: 20120204268
    Abstract: The present invention discloses a method and apparatus for protecting information based on a data card, and the method comprises: selecting information which needs to be hidden in a terminal device; and storing said information which needs to be hidden in a hidden partition of the data card. The present invention makes attackers not perceive the existence of the information and increases the security of the information in the data card, so as to protect the user's private information better.
    Type: Application
    Filed: May 21, 2010
    Publication date: August 9, 2012
    Applicant: ZTE Corporation
    Inventor: Qian Shi
  • Patent number: 8236852
    Abstract: The present invention includes compounds, pharmaceuticals and cosmetics having at least one (substituted phenyl)-propenal moiety. The compounds and compositions of the present invention are useful in the treatment or prevention of medical conditions including androgen associated conditions, androgen associated inflammation, acne, alopecia, hirsutism, a wound, prostate cancer, bladder cancer, liver cancer, breast cancer and Kennedy's disease.
    Type: Grant
    Filed: January 8, 2008
    Date of Patent: August 7, 2012
    Assignee: Androscience Corporation
    Inventors: Charles C. Y. Shih, Qian Shi, Hui-Kang Wang, Ching-Yuan Su
  • Patent number: 8202905
    Abstract: The present invention includes compounds, pharmaceuticals and cosmetics having at least one (substituted phenyl)-propenal moiety. The compounds and compositions of the present invention are useful in the treatment or prevention of medical conditions including androgen associated conditions, androgen associated inflammation, acne, alopecia, hirsutism, a wound, prostate cancer, bladder cancer, liver cancer, breast cancer and Kennedy's disease.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: June 19, 2012
    Assignee: Androscience Corporation
    Inventors: Charles C. Y. Shih, Qian Shi, Hui-Kang Wang, Ching-Yuan Su
  • Publication number: 20120046247
    Abstract: This invention relates to compounds of Formula (I), (II), or (III) as shown in the specification, which contain a 1,5-diphenylpenta-1,4-dien-3-one backbone. These compounds can be used to treat cancer, inflammatory disease, or autoimmune disease.
    Type: Application
    Filed: August 16, 2011
    Publication date: February 23, 2012
    Inventors: Charles C-Y Shih, Toshio Kitamura, Qian Shi, Toshiyuki Kawashima, Hui-Kang Wang
  • Publication number: 20120029018
    Abstract: The present invention provides compounds of Formula I: compositions containing the same, and methods of use thereof such as for the treatment of cancer.
    Type: Application
    Filed: August 25, 2009
    Publication date: February 2, 2012
    Inventors: Kuo-Hsiung Lee, Qian Shi, Xiaoming Yang, Kenneth F. Bastow, Jau-Chen Lin, Pan-Chyr Yang
  • Publication number: 20110275707
    Abstract: Compounds of Formulas I are described, along with methods of using such compounds for the treatment of cancer and pharmaceutical formulations thereof.
    Type: Application
    Filed: December 16, 2009
    Publication date: November 10, 2011
    Inventors: Kuo-Hsiung Lee, Yizhou Dong, Qian Shi, Kenneth F. Bastow, Pei-Chi Wu
  • Publication number: 20100292342
    Abstract: The present invention includes compounds, pharmaceuticals and cosmetics having at least one (substituted phenyl)-propenal moiety. The compounds and compositions of the present invention are useful in the treatment or prevention of medical conditions including androgen associated conditions, androgen associated inflammation, acne, alopecia, hirsutism, a wound, prostate cancer, bladder cancer, liver cancer, breast cancer and Kennedy's disease.
    Type: Application
    Filed: May 11, 2010
    Publication date: November 18, 2010
    Inventors: Charles C.Y. Shih, Qian Shi, Hui-Kang Wang, Ching-Yuan Su
  • Publication number: 20100248271
    Abstract: The present invention provides methods of detecting cancer using biomarkers.
    Type: Application
    Filed: April 2, 2010
    Publication date: September 30, 2010
    Inventors: Alexander Miron, James D. Iglehart, Lyndsay N. Harris, Xin Lu, Qian Shi
  • Publication number: 20100003415
    Abstract: A high voltage ceramic and glass insulator with a function film is provided to resist pollution flashover and a preparation method is provided to produce the high voltage insulators. It is a common high voltage insulator covered with a layer of nano meter level inorganic film with the function of raising pollution flashover resisting, and the film is formed on the high voltage ceramic and glass insulator surface and made of a solution containing the titanium dioxide base, and the solution containing the titanium dioxide base includes a pure titanium dioxide solution or a binary compound oxide solution containing the titanium dioxide. The invention is suitably used for the power transmission and the transform line in the areas with the circumstance seriously polluted or in the remote mountainous areas.
    Type: Application
    Filed: March 30, 2006
    Publication date: January 7, 2010
    Inventors: Xianzhi Fu, Wenlin Zong, Ping Liu, Qian Shi, Wenxin Dai, Fuwang Liao, Xun Chen, Han Lin, Xuxu Wang, Wenxuan Wu, Yu Shao, Xueyong Li, Lixin Sun, Hongxian Chai
  • Publication number: 20090209877
    Abstract: A hand-held, automated qualitative fit tester (QLFT) for establishing gas mask fit integrity. The automated QLFT may be configured to utilize a pressure source in combination with a cartridge and a nebulizer to generate aerosols having size distributions and concentrations that are substantially the same as OSHA-approved manual units. The QLFT may further include a cartridge that contains the aerosol solution used to test mask integrity. The cartridge may be configured to recapture solution that collects on the interior walls of the nebulizer. The automated QLFT may also be equipped with a microprocessor for executing sequences that are in substantive compliance with 29 CFR 1910.134 and for writing to a data storage device. The automated aspects of the invention can reduce or negate the need for operating personnel to repeatedly and manually actuate a squeeze ball and record results manually, as is required with present OSHA-approved hand-held aerosol generators.
    Type: Application
    Filed: February 17, 2009
    Publication date: August 20, 2009
    Inventors: Hai Zhang, Will Zanto, Qian Shi, Greg Olson, Phillip Poeschl, Vincent Majkowski, Stuart J. Olstad
  • Publication number: 20090035362
    Abstract: The present invention includes methods and compositions useful for treating and preventing skin disorders, hair loss and other skin disorders. The compositions include an ARD enhancer in combination with a second compound or composition. In some embodiments the second compound is at least one of a bactericide, an antibiotic, an anti-microbial peptide, Vitamin A, a Vitamin A derivative, a retinoid, an anti-inflammatory compound, and anti-androgen compounds.
    Type: Application
    Filed: July 31, 2008
    Publication date: February 5, 2009
    Inventors: Charles C.Y. Shih, Ching-Yuan Su, Hui-Kang Wang, Qian Shi
  • Publication number: 20080188557
    Abstract: The present invention includes compounds, pharmaceuticals and cosmetics having at least one (substituted phenyl)-propenal moiety. The compounds and compositions of the present invention are useful in the treatment or prevention of medical conditions including androgen associated conditions, androgen associated inflammation, acne, alopecia, hirsutism, a wound, prostate cancer, bladder cancer, liver cancer, breast cancer and Kennedy's disease.
    Type: Application
    Filed: January 8, 2008
    Publication date: August 7, 2008
    Inventors: Charles C.Y. Shih, Qian Shi, Hui-Kang Wang, Ching-Yuan Su
  • Publication number: 20060145776
    Abstract: The voltage-controlled oscillator (VCO) in a frequency synthesizer using a phase-locked loop (PLL) is calibrated digitally during power up. The VCO has a coarse frequency control and a fine frequency control. The coarse control is a digital phase-locked loop to quantize the broad frequency range into limited number of frequency steps with a clock frequency divided from the VCO frequency, and to hold the phase-locked dc control voltage for the fine control. By limiting the number of frequency steps and clocking at a divided frequency of the VCO, the coarse control is speeded up. The fine control is [connected to the charge pump output as in] a regular PLL. By searching for the optimal control setting, the center frequency of the VCO is trimmed close to the wanted frequency for the PLL to lock. This allows small VCO gain without losing the tolerance of process and temperature variations. As a result, the PLL phase noise performance is improved.
    Type: Application
    Filed: January 5, 2005
    Publication date: July 6, 2006
    Inventors: Qian Shi, Kevin Wang
  • Patent number: 6903133
    Abstract: This invention features compounds having formula (I): wherein, R1, R2, R3, R4, R5, R6, R7, T, X, and Y are as defined herein. This invention also features a method for treating cancer. The method includes administrating to a subject in need thereof a compound of formula (I).
    Type: Grant
    Filed: October 14, 2003
    Date of Patent: June 7, 2005
    Assignee: Plantaceutica, Inc.
    Inventors: Qian Shi, Hui-Kang Wang, Masayoshi Oyama, John Robert Vance, Ming S. Chen
  • Publication number: 20050110550
    Abstract: The DCOC block is used in ZIF BB to form HPF function to cancel dc offset with a penalty of small silicon area and low power consumption. It is a LPF plus a voltage to current conversion (VIC) resistor, and can hook up with any BB opamp used in signal path, to form a feedback loop, with or without signal gain stages in the loop. The BB opamp is used as a summing point. The summing method is input current summing. The cutoff frequency of the HPF function is thus defined by the integrator, the VIC resistor, and the feedback resistor in the summing opamp. The presence of the VIC resistor can drastically reduce the integrator capacitor and resistor values and thus save silicon area or improve receiver performance.
    Type: Application
    Filed: November 24, 2003
    Publication date: May 26, 2005
    Inventors: Qian Shi, Liang Dai, Kevin Wang
  • Publication number: 20040138288
    Abstract: This invention features compounds having formula (I): 1
    Type: Application
    Filed: October 14, 2003
    Publication date: July 15, 2004
    Inventors: Qian Shi, Hui-Kang Wang, Masayoshi Oyama, John Robert Vance, Ming S. Chen